Age Well with Dr Sophie Shotter

Why we don't have a vitamin C skincare product with Tiina Meder from Meder Beauty

Tue, 31 Mar 2026 05:00:00 +0000

“With a high concentration of retinol, you can have such a spectacular effect, but you pay the price.”

Thanks for listening to Age Well with Dr Sophie Shotter!

Follow Tiina here: https://www.instagram.com/drtiinameder/

Follow Meder Beauty here: https://www.instagram.com/meder_beauty/

You can find out more at https://uk.mederbeauty.com/

Find out more about Dr Sophie by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Co-host: https://fionamattesini.co.uk/

*****

This show is sponsored by Primeadine – a clean, natural, and science-backed spermidine supplement – proven to up-regulate a range of health markers.

Buy now at https://oxfordhealthspan.com/ and use the discount code DRSOPHIE for 20% off

*****

This show is sponsored by Microbz – harnessing good bacteria directly from UK soil which means more diversity and at least 15 strains of good bacteria in every shot.

Buy now at https://microbz.co.uk/ and use the discount code SOPHIE20 for 20% off

The content in this podcast is for general information purposes only and is not meant to serve as medical advice or to replace or substitute advice given by, or consultation with, your doctor or any other healthcare professional. Please contact your healthcare provider if you have any questions or concerns about your health. Dr Sophie Shotter, her company and any employees or representatives are not liable for any claims arising out of or in connection with this podcast.

Mentioned in this episode:

This show is sponsored by Microbz – harnessing good bacteria directly from UK soil which means more diversity and at least 15 strains of good bacteria in every shot. Buy now at https://microbz.co.uk/ and use the discount code SOPHIE20 for 20% off.

This show is sponsored by Primeadine – a clean, natural, and science-backed spermidine supplement – proven to up-regulate a range of health markers. Buy now at https://oxfordhealthspan.com/ and use the discount code DRSOPHIE for 20% off.

Hyperbaric oxygen and why people are using it - from serious disease to chronic insomnia – with Alan Trim

Tue, 24 Mar 2026 05:00:00 +0000

“I was cynical and desperate – but the results were dramatic.”

Thanks for listening to Age Well with Dr Sophie Shotter!

Follow Alan here: https://www.instagram.com/alan.trim/

Follow Oxidise here: https://www.instagram.com/oxydise.uk/

You can find out more at https://oxydise.co.uk/

The wellness centre in Cambridgeshire offers HBOT; dry floatation; IV wellness drips; cryotherapy, and red light therapy. Go to https://oxydisewellness.co.uk/

Find out more about Dr Sophie by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Co-host: https://fionamattesini.co.uk/

*****

This show is sponsored by Microbz – harnessing good bacteria directly from UK soil which means more diversity and at least 15 strains of good bacteria in every shot.

Buy now at https://microbz.co.uk/ and use the discount code SOPHIE20 for 20% off

***

This show is sponsored by Primeadine – a clean, natural, and science-backed spermidine supplement – proven to up-regulate a range of health markers.

Buy now at https://oxfordhealthspan.com/ and use the discount code DRSOPHIE for 20% off

Mentioned in this episode:

A chat with Emilie Lavinia - The Independent's Fitness and Wellbeing Editor

Tue, 17 Mar 2026 05:00:00 +0000

"I have an interesting relationship with tracking."

Thanks for listening to Age Well with Dr Sophie Shotter!

Follow Emilie at https://www.instagram.com/emilielaviniauk/

Listen to Well Enough here https://podcasts.apple.com/gb/podcast/well-enough/id1839434349

Find out more about Dr Sophie by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Co-host: https://fionamattesini.co.uk/

*****

This show is sponsored by Primeadine – a clean, natural, and science-backed spermidine supplement – proven to up-regulate a range of health markers.

Buy now at https://oxfordhealthspan.com/ and use the discount code DRSOPHIE for 20% off

*****

This show is sponsored by Microbz – harnessing good bacteria directly from UK soil which means more diversity and at least 15 strains of good bacteria in every shot.

Buy now at https://microbz.co.uk/ and use the discount code SOPHIE20 for 20% off

***

Mentioned in this episode:

The anxiety guide inc. a full CBD oil explainer + anti-anxiety supplements

Tue, 10 Mar 2026 05:00:00 +0000

“CBD users need to think about not only quality but dose.”

Thanks for listening to Age Well with Dr Sophie Shotter!

Find out more about Dr Sophie by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Co-host: https://fionamattesini.co.uk/

*****

This show is sponsored by Microbz – harnessing good bacteria directly from UK soil which means more diversity and at least 15 strains of good bacteria in every shot.

Buy now at https://microbz.co.uk/ and use the discount code SOPHIE20 for 20% off

***

This show is sponsored by Primeadine – a clean, natural, and science-backed spermidine supplement – proven to up-regulate a range of health markers.

Buy now at https://oxfordhealthspan.com/ and use the discount code DRSOPHIE for 20% off

*****

Mentioned in this episode:

Dr Louise Oliver on women and mid-life snoring

Tue, 03 Mar 2026 05:00:00 +0000

“A lot of women notice their sleep radically changes during perimenopause, and they start snoring.”

Thanks for listening to Age Well with Dr Sophie Shotter!

Find out more about Dr Sophie by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Co-host: https://fionamattesini.co.uk/

*****

This show is sponsored by Primeadine – a clean, natural, and science-backed spermidine supplement – proven to up-regulate a range of health markers.

Buy now at https://oxfordhealthspan.com/ and use the discount code DRSOPHIE for 20% off

*****

This show is sponsored by Microbz – harnessing good bacteria directly from UK soil which means more diversity and at least 15 strains of good bacteria in every shot.

Buy now at https://microbz.co.uk/ and use the discount code SOPHIE20 for 20% off.

Mentioned in this episode:

Jo Hurley on the vaginal + semen microbiome - the test, the interventions, the protocols

Tue, 24 Feb 2026 05:00:00 +0000

"The vaginal and seminal microbiomes are an emerging but really exciting field."

Thanks for listening to Age Well with Dr Sophie Shotter!

Find out more about Dr Sophie by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Co-host: https://fionamattesini.co.uk/

*****

This show is sponsored by Microbz – harnessing good bacteria directly from UK soil which means more diversity and at least 15 strains of good bacteria in every shot.

Buy now at https://microbz.co.uk/ and use the discount code SOPHIE20 for 20% off.

*****

This show is sponsored by Primeadine – a clean, natural, and science-backed spermidine supplement – proven to up-regulate a range of health markers.

Buy now at https://oxfordhealthspan.com/ and use the discount code DRSOPHIE for 20% off

Mentioned in this episode:

The nervous system ‘calm’ device that Sophie swears by - and a review of the latest health tech and wearables

Tue, 17 Feb 2026 05:00:00 +0000

“This is such an exciting and fast-moving space.”

Thanks for listening to Age Well with Dr Sophie Shotter!

Find out more about Dr Sophie by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Co-host: https://fionamattesini.co.uk/

This show is sponsored by Primeadine – a clean, natural, and science-backed spermidine supplement – proven to up-regulate a range of health markers.

Buy now at https://oxfordhealthspan.com/ and use the discount code DRSOPHIE for 20% off

*****

This show is sponsored by Microbz – harnessing good bacteria directly from UK soil which means more diversity and at least 15 strains of good bacteria in every shot.

Buy now at https://microbz.co.uk/ and use the discount code SOPHIE20 for 20% off.

Mentioned in this episode:

The UK's leading expert Dr Sharon Wong on hair loss, hair shedding, and eczema

Tue, 10 Feb 2026 05:00:00 +0000

“The diet you have for your body is the exact same diet for your hair”

Follow Sharon here >> https://www.instagram.com/drsharonwong/?hl=en

Find out more here >> https://www.drsharonwong.com/

Get DOSE here >> https://www.dosemyhair.com/

*****

This show is sponsored by Microbz – harnessing good bacteria directly from UK soil which means more diversity and at least 15 strains of good bacteria in every shot.

Buy now at https://microbz.co.uk/ and use the discount code SOPHIE20 for 20% off.

*****

This show is sponsored by Primeadine – a clean, natural, and science-backed spermidine supplement – proven to up-regulate a range of health markers.

Buy now at https://oxfordhealthspan.com/ and use the discount code DRSOPHIE for 20% off

*****

Thanks for listening to Age Well with Dr Sophie Shotter.

Find out more about Dr Sophie by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Co-host: https://fionamattesini.co.uk/

Mentioned in this episode:

"MCAS and histamine intolerance are so prevalent - yet most people have never heard of either" - Dr Tina Peers

Tue, 03 Feb 2026 05:00:00 +0000

“It’s thought that 17 to 20% of the population have abnormal mast cells.”

Follow Dr Tina on Insta here: https://www.instagram.com/drtinapeers/

Find out more at https://www.drtinapeers.com/

*****

This show is sponsored by Primeadine – a clean, natural, and science-backed spermidine supplement – proven to up-regulate a range of health markers.

Buy now at https://oxfordhealthspan.com/ and use the discount code DRSOPHIE for 20% off.

*****

This show is sponsored by Microbz – harnessing good bacteria directly from UK soil which means more diversity and at least 15 strains of good bacteria in every shot.

Buy now at https://microbz.co.uk/ and use the discount code SOPHIE20 for 20% off.

*****

Thanks for listening to Age Well with Dr Sophie Shotter.

Find out more about Dr Sophie by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Co-host: https://fionamattesini.co.uk/

Mentioned in this episode:

My incredible chat with Jo Woodhurst from Ancient and Brave

Tue, 27 Jan 2026 05:00:00 +0000

“If you can have a favourite mineral, magnesium would be mine!”

Follow Jo on Insta here: https://www.instagram.com/jo_woodhurst_nutrition/?hl=en-gb

You can also buy some of the supplements mentioned from https://ancientandbrave.earth/

Thanks for listening to Age Well with Dr Sophie Shotter!

Find out more about Dr Sophie by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

*****

This show is sponsored by Nooānce Paris - offering award winning premium skincare and next-generation LED masks.

Head to https://www.nooance-paris.com/ – and get 15% off with the code DRSOPHIE

*****

This show is sponsored by Microbz – harnessing good bacteria directly from UK soil which means more diversity and at least 15 strains of good bacteria in every shot.

Buy now at https://microbz.co.uk/ and use the discount code SOPHIE20 for 20% off.

*****

This show is sponsored by Primeadine – a clean, natural, and science-backed spermidine supplement – proven to up-regulate a range of health markers.

Buy now at https://oxfordhealthspan.com/ and use the discount code DRSOPHIE for 20% off.

*****

This podcast was produced by https://thepodcastpeople.co/

Co-host: https://fionamattesini.co.uk/

Mentioned in this episode:

This show is sponsored by NOOANCE Paris - offering next-gen LED masks and premium skincare with powerful, precisely dosed active ingredients. Buy now at https://www.nooance-paris.com and use the discount code DRSOPHIE for 15% off.

USA supplements ‘tourism’ – the latest melatonin headlines – and a possible new pathway for Alzheimer’s

Tue, 20 Jan 2026 05:00:00 +0000

"From GABA to DHEA, why are so many things not available in the UK?"

Thanks for listening to Age Well with Dr Sophie Shotter!

Find out more about Dr Sophie by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

*****

This show is sponsored by Nooānce Paris - offering award winning premium skincare and next-generation LED masks.

Head to https://www.nooance-paris.com/ – and get 15% off with the code DRSOPHIE

*****

This show is sponsored by Microbz – harnessing good bacteria directly from UK soil which means more diversity and at least 15 strains of good bacteria in every shot.

Buy now at https://microbz.co.uk/ and use the discount code SOPHIE20 for 20% off.

*****

This show is sponsored by Primeadine – a clean, natural, and science-backed spermidine supplement – proven to up-regulate a range of health markers.

Buy now at https://oxfordhealthspan.com/ and use the discount code DRSOPHIE for 20% off.

*****

This podcast was produced by https://thepodcastpeople.co/

Co-host: https://fionamattesini.co.uk/

Mentioned in this episode:

Why soil based probiotics are so different, and so powerful – with Katie Ward from Microbz

Tue, 13 Jan 2026 05:00:00 +0000

“What we find in the soil adds a breadth of highly powerful microorganisms.”

Thanks for listening to Age Well with Dr Sophie Shotter!

Find out more about Dr Sophie by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

Thanks to Katie Ward for guesting.

You can check out and buy the range at https://microbz.co.uk/

And follow Microbz on Instagram here: https://www.instagram.com/microbzprobiotics/?hl=en

This show is sponsored by Microbz – harnessing good bacteria directly from UK soil which means more diversity and at least 15 strains of good bacteria in every shot.

Buy now at https://microbz.co.uk/ and use the discount code SOPHIE20 for 20% off.

This show is sponsored by Primeadine – a clean, natural, and science-backed spermidine supplement – proven to up-regulate a range of health markers.

Buy now at https://oxfordhealthspan.com/ and use the discount code DRSOPHIE for 20% off.

This show is sponsored by NOOANCE Paris - offering next-gen LED masks and premium skincare with powerful, precisely dosed active ingredients.

Buy now at https://www.nooance-paris.com and use the discount code DRSOPHIE for 15% off.

Mentioned in this episode:

The wellness trends to watch in 2026

Tue, 06 Jan 2026 05:01:00 +0000

From social saunas to next-gen protein shakes

Thanks for listening to Age Well with Dr Sophie Shotter!

This show is sponsored by Primeadine – a clean, natural, and science-backed spermidine supplement – proven to up-regulate a range of health markers.

Buy now at https://oxfordhealthspan.com/ and use the discount code DRSOPHIE for 20% off.

This show is sponsored by Microbz – harnessing good bacteria directly from UK soil which means more diversity and at least 15 strains of good bacteria in every shot.

Buy now at https://microbz.co.uk/ and use the discount code SOPHIE20 for 20% off.

Find out more about Dr Sophie by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Co-host: https://fionamattesini.co.uk/

Mentioned in this episode:

Dr Sophie's 2025 favourite things (from skincare to supplements and everything in-between)

Tue, 30 Dec 2025 05:00:00 +0000

Thank you to everyone who listened this year - enjoy this round-up episode!

Thanks for listening to Age Well with Dr Sophie Shotter – please rate and review the show if you get a moment.

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Co-host: https://fionamattesini.co.uk/

Mentioned in this episode:

A chat with leading sleep guru Kathryn Pinkham (let's all improve our sleep in 2026!)

Tue, 23 Dec 2025 05:00:00 +0000

“This is about re-setting your natural sleep drive.”

Find out more about Kathryn – and book a consultation - at https://www.theinsomniaclinic.co.uk/

Check out some of Kathryn’s case studies and reviews here: https://www.theinsomniaclinic.co.uk/results-we-get

Follow Kathryn on Instagram here: https://www.instagram.com/theinsomniaclinic/

Thanks for listening to Age Well with Dr Sophie Shotter – please rate and review the show if you get a moment.

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Co-host: https://fionamattesini.co.uk/

Mentioned in this episode:

A super quick peptides explainer (and the peptide products that should be on your Christmas list)

Tue, 16 Dec 2025 05:00:00 +0000

“These are really clever messengers that tell your skin what to do.”

Thanks for listening to Age Well with Dr Sophie Shotter – please rate and review the show if you get a moment.

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Co-host: https://fionamattesini.co.uk/

Mentioned in this episode:

Why spermidine is the longevity supplement going mainstream in 2026 - with Primeadine’s Leslie Kenny

Tue, 09 Dec 2025 05:01:00 +0000

“Everything I have been doing for the last 21 years has been about reducing inflammation.”

You can buy Primeadine and learn more about spermidine at https://oxfordhealthspan.com

The Oxford Longevity Project can be found at https://oxfordlongevityproject.org

And do follow Leslie on Instagram https://www.instagram.com/lesliesnewprime/?hl=en

More info (inc studies) further below.

Thanks for listening to Age Well with Dr Sophie Shotter – please rate and review the show if you get a moment.

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Co-host: https://fionamattesini.co.uk/

More info (inc studies):

https://pmc.ncbi.nlm.nih.gov/articles/PMC8612618/

https://www.nature.com/articles/s41556-024-01468-x

https://www.aging-us.com/news-room/spermidine-and-protein-restriction-independently-protect-brain-and-body-from-aging-in-flies

https://www.sciencedirect.com/science/article/abs/pii/S1568163725001333

https://www.telegraph.co.uk/health-fitness/diet/weight-loss/anti-ageing-fasting-benefits-without-giving-up-eating/

Mentioned in this episode:

Why 2025 saw a blepharoplasty boom - with Dr Elizabeth Hawkes

Tue, 02 Dec 2025 05:01:00 +0000

“We're definitely going through a blepharoplasty boom.”

Follow Dr Elizabeth on Instagram here: https://www.instagram.com/dr_elizabethhawkes/

Find out more and make a booking with Dr Elizabeth here: https://drelizabethhawkes.com/

Thanks for listening to Age Well with Dr Sophie Shotter – please rate and review the show if you get a moment.

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Co-host: https://fionamattesini.co.uk/

Ayahuasca, psychedelics, and Dr Joe Tafur's journey from trained doctor to the Peruvian Amazon

Tue, 25 Nov 2025 05:00:00 +0000

"I had the opportunity to enter into a traditional ceremony and I had a major shift."

Find out more at https://www.drjoetafur.com/

Dr Joe has written two books, both available now:

‘The fellowship of the river’ and ‘Medicine song: spiritual healing and the psychedelic renaissance’

Follow Dr Joe on Insta https://www.instagram.com/dr.joetafur/

Find him on all other socials too.

Psychedelics have been used for thousands of years in traditional indigenous ceremonies – particularly in parts of South America. Research is showing very promising results for psychedelic therapy when it comes to things like treatment resistant depression, PTSD, and addiction. However despite a growing body of evidence on what psychedelic therapy can do, ayahuasca (along with other psychedelics) is classified in the UK (and in many other parts of the world) as a Schedule 1 drug. Dr Sophie is therefore not advocating the use of any illegal substances.

Thanks for listening to Age Well with Dr Sophie Shotter – please rate and review the show if you get a moment.

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Co-host: https://fionamattesini.co.uk/

Ashwagandha. Is it the ultimate stress fixer + the facts behind the Danish ban

Tue, 18 Nov 2025 05:00:00 +0000

"This is possibly a regulation problem not an ashwagandha problem."

Thanks for listening to Age Well with Dr Sophie Shotter – please rate and review the show if you get a moment.

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Co-host: https://fionamattesini.co.uk/

Sarah Bradden’s incredible story of recovery – and how this led to The Bradden Method

Tue, 11 Nov 2025 05:01:00 +0000

"I was in and out of hospital… I was misdiagnosed with bowel cancer - and something happened to me in that session."

Follow Sarah here: https://www.instagram.com/sarahbradden/?hl=en

Find out more (and make a booking) at https://www.sarahbradden.com/

Thanks for listening to Age Well with Dr Sophie Shotter – please rate and review the show if you get a moment.

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Co-host: https://fionamattesini.co.uk/

Mentioned in this episode:

What's in my kit - from make-up artist Emma Rankin

Tue, 04 Nov 2025 05:00:00 +0000

“If someone said to me 'you could only have one thing', I’d go for this…”

Follow Emma here: https://www.instagram.com/emmarankin/?hl=en

Thanks for listening to Age Well with Dr Sophie Shotter – please rate and review the show if you get a moment.

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Co-host: https://fionamattesini.co.uk/

Mentioned in this episode:

How I recovered from long COVID - Dr Tam Lewis

Tue, 28 Oct 2025 05:00:00 +0000

“A lot of people are getting different supplements in different doses from different brands - and hoping for the best.”

Find out more about Dr Tam and Wellgevity here: https://www.wellgevity.com/

Follow Dr Tam on Instagram here: https://www.instagram.com/drtam/

Thanks for listening to Age Well with Dr Sophie Shotter – please rate and review the show if you get a moment.

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Co-host: https://fionamattesini.co.uk/

Dr Nichola Conlon on ageing well - and figuring out our biological age

Tue, 21 Oct 2025 04:00:00 +0000

“Yes, trauma creates inflammation - and inflammation is a key driver of aging.”

Find out more about Dr Nichola and Nuchido Time+ here: https://nuchido.co.uk/

Follow Nichola here: https://www.instagram.com/drnicholaconlon/?hl=en

Listen to What’s My Age Again here: https://podcasts.apple.com/gb/podcast/whats-my-age-again/id1806655079

This is Nichola’s previous episode on NAD and Nuchido Time+ https://podcasts.apple.com/gb/podcast/we-now-have-hard-evidence-that-this-will-slow-cellular/id1713189123?i=1000665960901

This is Dr Sophie’s health testing episode: https://podcasts.apple.com/gb/podcast/a-review-of-at-home-health-test-kits/id1713189123?i=1000674816637

This is Dr Stacy Sim’s episode: https://podcasts.apple.com/cm/podcast/dr-stacy-sims-the-worlds-leading-voice-on-why-women/id1713189123?i=1000722600064

Thanks for listening to Age Well with Dr Sophie Shotter – please rate and review the show if you get a moment.

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Co-host: https://fionamattesini.co.uk/

Mentioned in this episode:

The truth about low testosterone and why so many men need TRT - with Dr Jeff Foster

Tue, 14 Oct 2025 04:00:00 +0000

"Testosterone deficiency is an unknown epidemic amongst men."

Dr Jeff is an NHS GP Partner and a Private GP - with a specialist interest in men’s health. He’s also the Director of Men’s Health at Manual the online men’s health clinic – and the Medical Director and founder of H3 Health, the U.K.’s first male (and female) health clinic aimed at the 40s.

Follow Jeff on Instagram here: https://www.instagram.com/drjefffoster/?hl=en

Find out more about Jeff here: https://www.drjefffoster.co.uk/

Thanks for listening to Age Well with Dr Sophie Shotter – please rate and review the show if you get a moment.

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Co-host: https://fionamattesini.co.uk/

Mentioned in this episode:

What we now know about eggs, sperm, and fertility (new data, new ideas)

Tue, 07 Oct 2025 04:00:00 +0000

“While you can’t change the *number* of eggs you’re born with, you can change the *quality*”

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Co-host: https://fionamattesini.co.uk/

Listen to the episode to get the full low-down on everything discussed. Here are a few more notes:

Polyunsaturated Fatty Acids (PUFAs) and Fish:

Studies have also suggested that PUFAs may promote fertility by improving egg quality and implantation (Gaskins & Chavarro, 2018). Several large-cohort studies have shown that women who report higher intakes of omega-3 PUFAs have higher fecundability and reduced risk of anovulation (no ovulation). Women who reported a higher intake of trans fatty acids were found to have greater risk of infertility and reduced fecundability (Chavarro et al., 2007; Mumford et al., 2016; Wise et al., 2018). (Trans fatty acids are a type of fat found primarily in fried and other foods that are made with partially hydrogenated oils, and they are known to raise cholesterol levels.)

Women who eat a lot of trans fatty acids have been found to have greater risk of fertility challenges (Chavarro et al., 2007; Mumford et al., 2016; Wise et al., 2018).

Soy:

See this comprehensive summary of the state of the research on phytoestrogens and soy by reproductive endocrinologist Amber Cooper, MD, at the Vios Fertility Institute in St. Louis, Missouri.) https://www.fertstert.org/article/S0015-0282(19)30621-1/fulltext

Quitting Drinking and Smoking:

Not only does drinking during pregnancy have significant risks for the fetus but drinking when trying to conceive can also pose problems. Alcohol has been shown to reduce female and male fertility, perhaps by impacting sperm quality (Fan et al., 2017; Karmon et al., 2017; La Vignera et al., 2013). If you’re having trouble conceiving, try reducing your alcohol intake.

Smoking can cause reproductive issues and impaired fertility. Cigarette smoking is associated with reduced ovarian function and lower pregnancy rates in women (Vanvoorhis et al., 1996). Male smoking is associated with reduced semen quality, sperm development, sperm maturation, and sperm function (Dai et al., 2015).

Recent studies have suggested that folic acid reduces the risk of miscarriage, while also conferring other benefits, such as better fertility and getting pregnant faster (Gaskins & Chavarro, 2018).

In a study lactolycopene seemed to improve sperm motility and morphology in healthy men, increasing the proportion of fast sperm and normal morphology (Williams et all, 2020).

Women who took FertilityBlend three times a day for three months had significantly more pregnancies (Lynn Marie Westphal et al., 2004). This positive finding was replicated in a subsequent larger controlled study (Westphal, Polan, & Trant, 2006).

https://www.yourfertility.org.au/sites/default/files/2018-08/Howtoavoidchemicalsthatcanreduce_fertility.pdf https://www.su.se/english/research/human-eggs-prefer-some-men-s-sperm-over-others-research-shows-1.503532

https://edition.cnn.com/2020/06/09/health/sperm-choice-female-eggs-wellness

https://www.healthline.com/health/substance-use/does-weed-affect-sperm#short-answer

https://www.glamour.com/story/foods-that-increase-fertility

Thanks for listening to Age Well with Dr Sophie Shotter – please rate and review the show if you get a moment

Mentioned in this episode:

Grounding sheets (and how an insomniac got their "best ever night's sleep")

Tue, 30 Sep 2025 04:00:00 +0000

“Just as the sun gives us vitamin D, why should it seem so strange that the Earth gives us something beyond a surface to walk and build on?”

Thanks for listening to Age Well with Dr Sophie Shotter – please rate and review the show if you get a moment.

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Co-host: https://fionamattesini.co.uk/

Mentioned in this episode:

A chat with cult facialist and skincare visionary... Sarah Chapman

Tue, 23 Sep 2025 04:00:00 +0000

“I've seen so many fads [and] what I'm interested in is evidence based results.”

Find out more and make a booking at The Skinesis Clinic here: https://www.sarahchapman.com/

Follow Sarah Chapman London on Instagram here: https://www.instagram.com/sarahchapmanlondon/?hl=en

Listen to the episode to get the full low-down on how Sarah ages well.

Thanks for listening to Age Well with Dr Sophie Shotter – please rate and review the show if you get a moment.

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Co-host: https://fionamattesini.co.uk/

Mentioned in this episode:

Metformin + ivermectin + rapamycin (etc) << a ‘longevity’ drugs explainer

Tue, 16 Sep 2025 04:00:00 +0000

“Some of these have data and others… not so much."

Thanks for listening to Age Well with Dr Sophie Shotter – please rate and review the show if you get a moment.

Some notes and studies etc:

Metformin is increasingly thought to protect against cancer, heart disease, and potentially even Alzheimer’s. Read more: https://pubmed.ncbi.nlm.nih.gov/28802803-metformin-reduces-all-cause-mortality-and-diseases-of-ageing-independent-of-its-effect-on-diabetes-control-a-systematic-review-and-meta-analysis/

Scientists have also shown that Metformin encourages the growth of certain good gut bacteria, which leads to increased production of short-chain fatty acids. Read more: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681099/

A recent longitudinal study shows we still need more research and data. Read more: https://peterattiamd.com/a-recent-metformin-study-casts-doubts-on-longevity-indications/

Dr Sophie mentioned the Targeting Aging with Metformin or TAME study.

Some studies have also shown that metformin can inhibit muscle growth. Read more: https://www.lifespan.io/news/metformin-and-resistance-training-downside-and-upside/#:~:text=Metformin%20restricts%20muscle%20building%20but%20makes%20gene%20expression%20more%20youthful.&text=A%20new%20study%20published%20in,it%20promotes%20youthful%20gene%20expression.

A 2025 American Society of Clinical Oncology Annual Meeting looked at a study of ivermectin in combination with immunotherapy for patients with breast cancer and showed no significant benefit. Read: https://www.oncologynewscentral.com/asco-conference-coverage

Dr Sophie mentioned Primeadine® Original Spermidine.

MORE STUDIES:

https://www.uea.ac.uk/about/news/article/anti-aging-drug-rapamycin-extends-lifespan-as-effectively-as-eating-less

https://www.sciencedirect.com/science/article/pii/S0531556523000876

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Co-host: https://fionamattesini.co.uk/

How to radically improve your digital nutrition - with Dr Kaitlyn Regehr

Tue, 09 Sep 2025 04:00:00 +0000

“We're not the consumers of social media – we’re the product (or rather, our time and attention is).”

Find out more about Dr Kaitlyn here: https://profiles.ucl.ac.uk/88177-kaitlyn-regehr

Follow Dr Kaitlyn on socials – she does occasionally post! – via https://www.instagram.com/kaitlynregehr/?hl=en-gb

Thanks for listening to Age Well with Dr Sophie Shotter – please rate and review the show if you get a moment.

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Co-host: https://fionamattesini.co.uk/

NEW data / thinking on insulin – from Alzheimer’s to PCOS - Prof Ben Bikman

Tue, 02 Sep 2025 04:01:00 +0000

“This insulin resistance has been shown to begin to occur in people as early as their 20s.”

Find out more about Prof Ben here: https://www.benbikman.com/

Follow Prof Ben here: https://www.instagram.com/benbikmanphd/?hl=en

Find out more about Insulin IQ here: https://insuliniq.com/

Thanks for listening to Age Well with Dr Sophie Shotter – please rate and review the show if you get a moment.

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Co-host: https://fionamattesini.co.uk/

Mentioned in this episode:

Viagra + Cialis + NEW options for female libido (and does Viagra lower the risk of Alzheimer’s?)

Tue, 26 Aug 2025 04:00:00 +0000

“There’s a lack of research into libido for women [and] this idea that we should only develop drugs that work on the brain rather than giving women a genital stimulant."

NOTES:

A study at UCL found that Viagra might help to lower the risk of Alzheimer’s disease.

Bryan Johnson quoted nearly 10 individual studies that talk about Viagra’s effects on longevity. Read more here: https://www.science.org/content/article/viagra-and-other-unlikely-candidates-lead-hunt-new-longevity-drugs

Here’s the Dr Nathan Bryan episode: https://podcasts.apple.com/gb/podcast/loss-of-nitric-oxide-is-directly-linked-to-almost/id1713189123?i=1000664439672

Here’s the Dr Tracy Gapin episode: https://podcasts.apple.com/gb/podcast/from-sex-drive-to-fertility-this-is-a-mens-health/id1713189123?i=1000666738097

Cordyceps research has found it to increase testosterone, while a review concluded that it could enhance libido and sexual performance. Read more: https://pubmed.ncbi.nlm.nih.gov/11712663/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791983/

Other references www.pharmaceutical-journal.com/news-and-analysis/infographics/three-decades-of-viagra/20202847.article

www.nhs.uk/medicines/sildenafil-viagra/

www.medicines.org.uk/emc/product/7124/pil#gref

www.medicines.org.uk/emc/product/7430/pil#gref

In 2014, a meta analysis of many studies showed cardioprotective effects of PDE5 inhibitors.

In 2018, Cialis showed improved cardiovascular dysfunction and overactive bladder in rats, and in 2019, it was shown to reverse signs of heart failure in sheep.

In 2021, a study out of Karolinska Institute in Sweden showed that PDE5 inhibitors may extend life in men with coronary artery disease. https://academic.oup.com/jsm/article/20/1/38/6986842

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

Co-host and producer https://fionamattesini.co.uk/

Mentioned in this episode:

Dr Stacy Sims - the world's leading voice on why women need to exercise differently to men

Tue, 19 Aug 2025 04:00:00 +0000

“A lot of the exercise stuff being promoted out there is based on male data [while] looking through a male lens.”

Find out more and get Dr Stacy’s FREE newsletter and articles at: https://www.drstacysims.com/

Get 15% off Dr Stacy’s online courses at https://www.drstacysims.com/product_guide using the code DRSTACYSIMS15OFF

Dr Stacy’s socials:

https://www.facebook.com/drstacysims

https://www.instagram.com/drstacysims

https://www.youtube.com/channel/UCPD55VPa1ZWx1a_nzWC2VJA

https://www.linkedin.com/in/stacy-t-sims-phd/

The below were all mentioned by Dr Stacy:

https://drgabriellelyon.com/

https://www.vaginacoach.com/ and https://www.buffmuffapp.com/

This was the other app mentioned https://www.junofem.com/femfit

Thanks for listening to Age Well with Dr Sophie Shotter – please rate and review the show if you get a moment.

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Co-host: https://fionamattesini.co.uk/

Mentioned in this episode:

Why the science world is getting so excited about post-biotics (short explainer)

Tue, 12 Aug 2025 04:00:00 +0000

“There are a few really interesting examples of postbiotics' potential in helping ward off disease”

Sophie mentions a few brands – listen in to the episode to find out more (also now adding https://myotahealth.com/ to the mix – a newer prebiotic brand).

The at-home health test eps is here: https://podcasts.apple.com/ie/podcast/a-review-of-at-home-health-test-kits/id1713189123?i=1000674816637

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

Co-host and producer https://fionamattesini.co.uk/

Mentioned in this episode:

Forget everything you know about taking magnesium and other mineral supp's - and meet Caroline Alan

Tue, 05 Aug 2025 04:00:00 +0000

“He said, ‘try these - they might help you feel better’ - and over the space of about 8 or 9 months, I just stopped getting sick.”

Head to https://www.beamminerals.com/ to find out more

Buy Beam Minerals in the UK via https://longevity-essentials.com/

Caroline mentioned OligoScan - a non-invasive method used to assess mineral deficiencies, antioxidant levels, and heavy metal accumulation in the body - using spectrophotometry. It involves a device to measure the light absorbed by tissues in the palm, providing insights into intracellular levels of these substances.

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

Co-host and producer https://fionamattesini.co.uk/

Mentioned in this episode:

Ozempic and other weight loss drugs - the headlines, the concerns, and everything you need to know

Tue, 29 Jul 2025 04:00:00 +0000

“Surely there’s an issue in that if people’s appetite is so diminished, the last thing they want to do is have huge servings of fibre-rich food - which is a key pillar of gut health?”

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

Co-host and producer https://fionamattesini.co.uk/

Mentioned in this episode:

Chemicals in personal care and cleaning products. Should we be worried?

Tue, 22 Jul 2025 04:00:00 +0000

"Some chemicals can even imitate certain hormones or potentially turn one hormone into another."

Thanks for listening to Age Well with Dr Sophie Shotter – please rate and review the show if you get a moment.

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Co-host: https://fionamattesini.co.uk/

SOURCES and articles

https://madesafe.org/blogs/viewpoint/toxic-chemicals-in-air-fresheners

https://www.independent.co.uk/extras/indybest/house-garden/kitchen-accessories/best-natural-cleaning-products-brands-home-that-work-cheap-disinfect-effective-uk-a9624281.html

https://www.forbes.com/sites/brucelee/2018/03/04/cleaning-your-house-may-be-as-bad-as-smoking-20-cigarettes-a-day/

https://www.forbes.com/sites/amywestervelt/2012/09/10/five-things-you-should-know-before-you-clean-your-house/

https://www.womenshealthmag.com/uk/beauty/skin/a706460/best-natural-deodorants/

https://www.independent.co.uk/extras/indybest/fashion-beauty/beauty/best-natural-deodorant-uk-b1804046.html

https://goop.com/beauty/skin/mineral-sunscreen-guide/?srsltid=AfmBOorUrh4myqMZLa9g3s0W8cmdm6Fc0OpuiBloJ7z8kTNV9r_KbJHn

https://www.safecosmetics.org/chemicals/formaldehyde/

https://goop.com/beauty/personal-care/6-of-the-most-common-endocrine-disruptors-and-how-to-avoid-them/

https://goop.com/wellness/detox/how-to-avoid-common-toxic-chemicals/?srsltid=AfmBOor0qXmtJxvkcJZ80uKaJ7YKrQwzURSjLgu9v5cLff-irnsq7s-d

https://www.vogue.co.uk/article/indie-perfumes#:~:text=in%20this%20article:-,Unifrom,Horace

STUDIES:

https://pubmed.ncbi.nlm.nih.gov/21313993/

https://www.ewg.org/guides/substances/22127-QUATERNARYAMMONIUMCOMPOUNDSBENZYLC818ALKYLDIMETHYLCHLORIDES/

https://www.sciencedirect.com/science/article/pii/S0045653523018374#sec3

https://www.ewg.org/news-insights/news-release/2023/09/cleaning-products-emit-hundreds-hazardous-chemicals-new-study

https://oem.bmj.com/content/74/1/39

https://www.thoracic.org/about/newsroom/press-releases/resources/women-cleaners-lung-function.pdf

https://www.sciencedirect.com/science/article/pii/S0160412023000120?via%3Dihub

https://health.ec.europa.eu/publications/sccs-opinion-ethylhexyl-methoxycinnamate-ehmc-cas-no-5466-77-383834-59-7-ec-no-226-775-7629-661-9_en

https://academic.oup.com/ieam/article-abstract/17/5/940/7727851?redirectedFrom=fulltext&login=false

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648445/#R16

https://www.niehs.nih.gov/health/topics/agents/endocrine/index.cfm

https://www.sciencedirect.com/science/article/pii/S0160412020320213#s0130

Mentioned in this episode:

All things breast surgery (and is breast implant illness a thing?) - Nora Nugent

Tue, 15 Jul 2025 04:01:00 +0000

"New technologies [mean] progress. But don't jump on the bandwagon too early - long term data is important."

Find out more and book a consultation here: https://noranugent.co.uk/

Follow Nora on Instagram here: https://www.instagram.com/noranugent/?hl=en

You can also follow: https://www.instagram.com/noranugentplasticsurgery/

Find out more about Dr Sophie by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

Co-host and producer https://fionamattesini.co.uk/

Mentioned in this episode:

Meta Cell Technology (MCT): is this the biggest skincare breakthrough in years?

Tue, 08 Jul 2025 04:00:00 +0000

“It's totally game changing technology.”

Find out more (and book an MCT treatment) by heading to https://drsophieshotter.com/

You can also book a treatment for exosome / PRP therapy - and buy exosome skincare.

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

Co-host and producer https://fionamattesini.co.uk/

Mentioned in this episode:

Signs of thyroid issues + an iodine explainer + the menopause link

Tue, 01 Jul 2025 04:01:00 +0000

"The WHO estimates that over 1.9 billion people have inadequate iodine nutrition."

According to a recent review, multiple studies have suggested a link between a lack of selenium and Hashimoto’s disease, the most common cause of hypothyroidism aside from iodine deficiency. Read more: https://www.cureus.com/articles/42327-minerals-an-untapped-remedy-for-autoimmune-hypothyroidism

Some evidence suggests that zinc is involved in regulating the production and activity of thyroid hormones. Read more: https://pubmed.ncbi.nlm.nih.gov/30982439/

Levels of zinc might be linked with our levels of thyroid hormones and TSH. Some evidence suggests that magnesium may be involved in how your body absorbs iodine. This absorption is an important step in making thyroid hormones. Read more: https://www.cureus.com/articles/42327-minerals-an-untapped-remedy-for-autoimmune-hypothyroidism

Iodine and the diet – read more here: https://www.bbc.co.uk/programmes/articles/2KTr1JPxY7JjQJ3mmSZ9f0d/what-s-the-best-way-to-get-iodine-in-your-diet

A study from the Journal of Dermato-Endocrinology also shows that depleted levels of the thyroid hormone can impact the epidermal barrier function, which helps your skin to retain moisture. Read more: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219173/

According to a study from the Journal of Hypothyroidism, over 80% of people with low thyroid hormone levels (commonly caused by low iodine) feel more sensitive to the cold. Read more: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895281/

List of functional doctors / patients-turned-influencers: Dr Alisha Knicely Dr. Katie Rothwell Dr. Rachel Vong Dr. Robin Urekar Aggie McCabe Priscilla Blevins

This is not an exhaustive list. Please do your research and check the credentials of any one claiming to be able to help with your thyroid issues - and run their advice past your GP.

Thanks for listening to Age Well with Dr Sophie Shotter – please rate and review the show if you get a moment.

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Co-host: https://fionamattesini.co.uk/

Product favourites w/ journalist and Beauty Director Alessandra Steinherr

Tue, 24 Jun 2025 04:00:00 +0000

“I've been a peptide person for as long as these were available.”

Follow Alex on Instagram here: https://www.instagram.com/alexsteinherr/?hl=en

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

Co-host and producer https://fionamattesini.co.uk/

Mentioned in this episode:

A 20 minute creatine explainer inc. new findings on mental health

Tue, 17 Jun 2025 04:00:00 +0000

“There are quite a few myths – but lots of new research” - Dr Sophie

Thanks for listening to Age Well with Dr Sophie Shotter – please rate and review the show if you get a moment.

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Co-host: https://fionamattesini.co.uk/

Relevant research and studies:

https://journals.lww.com/nsca-scj/pages/articleviewer.aspx?year=2016&issue=04000&article=00015&type=Fulltext&fbclid=IwAR3hhAHX6GycCIbI2FSgjOVC1yEZwCdIYkXGRPftp-1s8hexKx_YdiOcoec

https://pubmed.ncbi.nlm.nih.gov/11985880/

https://ajp.psychiatryonline.org/doi/full/10.1176/appi.ajp.2012.12010009

https://www.mdpi.com/2072-6643/13/3/877

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7871530/

https://pubmed.ncbi.nlm.nih.gov/28397310/

https://pubmed.ncbi.nlm.nih.gov/21394604/

https://pubmed.ncbi.nlm.nih.gov/33578876/

https://www.mdpi.com/2072-6643/17/6/1081

https://pubmed.ncbi.nlm.nih.gov/15320650/

https://www.nature.com/articles/s41398-020-0741-x#Sec9

https://www.menshealth.com/nutrition/a62567487/should-teens-take-supplements/

https://pubmed.ncbi.nlm.nih.gov/39173400/

https://journals.lww.com/nsca-scj/pages/articleviewer.aspx?year=2016&issue=04000&article=00015&type=Fulltext&fbclid=IwAR3hhAHX6GycCIbI2FSgjOVC1yEZwCdIYkXGRPftp-1s8hexKx_YdiOcoec

https://www.tandfonline.com/doi/epdf/10.1080/15502783.2025.2502094?needAccess=true

https://www.mdpi.com/2072-6643/16/16/2772

https://alz-journals.onlinelibrary.wiley.com/doi/10.1002/trc2.70101

Mentioned in this episode:

New data on snacking + protein + sweeteners + early colorectal cancer (and more) – ZOE's Prof Sarah Berry

Tue, 10 Jun 2025 04:00:00 +0000

"You can't out-supplement a crap diet."

Find out more about Prof Sarah here: https://www.kcl.ac.uk/people/sarah-berry

Follow Prof Sarah here: https://www.instagram.com/drsarahberry/?hl=en

Buy ZOE’s Daily30+ here: https://zoe.com/daily30

Learn more about ZOE here: https://zoe.com/en-gb

Listen to the ZOE podcast here (and on Apple and Spotify): https://zoe.com/learn/category/podcasts

Follow ZOE here: https://www.instagram.com/zoe/

Find out more about ZOE’s processing scale here: https://zoe.com/learn/not-all-upfs-are-equal-health

Find out more about early-onset colon cancer here: https://zoe.com/learn/zoe-prospect-early-onset-colon-cancer

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

Co-host and producer https://fionamattesini.co.uk/

Mentioned in this episode:

The ultimate guide to happy, healthy hair – Tom Smith

Tue, 03 Jun 2025 04:00:00 +0000

“There are quite a few misconceptions around colour – especially balayage.”

Find out more about Tom here: https://www.tomsmithhd.com/

Follow Tom on Instagram here: https://www.instagram.com/tomsmithhd/?hl=en

This is Tom’s YouTube channel: https://www.youtube.com/@TOMSMITHHAIR

And you can book an appointment with Tom via Billi Currie Hair in London.

This is Sophie’s previous episode on hair: https://podcasts.apple.com/gb/podcast/hair-loss-hair-thinning-hair-health/id1713189123?i=1000650450018

Listen to the episode to get the full low-down on how Tom ages well – from his skincare to his supplements.

Thanks for listening to Age Well with Dr Sophie Shotter – please rate and review the show if you get a moment.

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Co-host: https://fionamattesini.co.uk/

Mentioned in this episode:

How to build a skincare brand that blends science with soul - Annee de Mamiel

Tue, 27 May 2025 04:00:00 +0000

“The body goes through about 1400 physiological reactions when we’re stressed – and this is undoubtedly reflected in the skin.”

Buy Annee's skincare range here: https://demamiel.com/

Follow De Mamiel skin on Instagram here: https://www.instagram.com/demamielskin/

Book a facial with Annee at the Agua Spa at the Sanderson in London.

Listen to the episode to get the full low-down on how Annee ages well – from her skincare to her supplements.

Thanks for listening to Age Well with Dr Sophie Shotter – please rate and review the show if you get a moment.

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Co-host: https://fionamattesini.co.uk/

Mentioned in this episode:

A new approach to the pelvic floor + a protein powder designed for women – Rachel Prince

Tue, 20 May 2025 04:05:00 +0000

“There's so many limiting beliefs women have that lifting weights will make their pelvic floor worse.”

Follow Reborn active on Instagram here: https://www.instagram.com/rebornactive/

Follow Louco on Instagram here: https://www.instagram.com/loucohealth/

Book a session with Rachel here: https://rebornactive.com/

Buy Louco here: https://louco.co/

There are plenty of ideas around modified exercises to help protect the pelvic floor. Here’s one example: https://www.youtube.com/watch?v=IBFGr9TpSn8

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram…

https://www.instagram.com/drsophieshotter/?hl=en

…and on Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

Co-host and producer https://fionamattesini.co.uk/

Mentioned in this episode:

How I recovered from PCOS + an autoimmune disease – and became pregnant - Liberty Mills

Tue, 13 May 2025 04:00:00 +0000

"We need to seriously think about endocrine disruptors"

Liberty’s book is out now: ‘360 Fertility: A twelve-week plan for optimising your chance of conception’

Buy Liberty’s book here: https://www.amazon.co.uk/dp/1035429578?ref=cm_sw_r_ffobk_cp_ud_dp_R1DCEEKPS41F7DNXREA6&ref_=cm_sw_r_ffobk_cp_ud_dp_R1DCEEKPS41F7DNXREA6&social_share=cm_sw_r_ffobk_cp_ud_dp_R1DCEEKPS41F7DNXREA6&bestFormat=true&previewDoh=1

Follow Liberty on Instagram here: https://www.instagram.com/mills.liberty/?hl=en

Dr Sophie and Liberty discussed water filtration and endocrine disruptors – here’s a previous episode with more info and the latest data: https://podcasts.apple.com/gb/podcast/is-tap-water-ok-water-filters-explained-the-buzz/id1713189123?i=1000673942291

More on SLE here (Liberty's condition): https://www.mountsinai.org/health-library/diseases-conditions/systemic-lupus-erythematosus

Get PCOS support here: https://www.verity-pcos.org.uk/

Martha Beck's book on integrity is called "The Way of Integrity: Finding the Path to Your True Self".

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

Co-host and producer https://fionamattesini.co.uk/

Mentioned in this episode:

The Magic of Mushrooms – Part 2 – Andrew Salter (Dirtea)

Tue, 06 May 2025 04:00:00 +0000

“What was cool 10 years ago was to drink copious amounts of alcohol and wake up with a hangover – now there’s a massive shift."

Follow Andrew on Instagram here: https://www.instagram.com/andrewpsalter/?hl=en

Follow Dirtea on Instagram here: https://www.instagram.com/dirteaworld/?hl=en

Buy Dirtea here: https://www.dirteaworld.com/

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

Co-host and producer https://fionamattesini.co.uk/

Mentioned in this episode:

Lifting weights is the panacea of longevity - Claire Sanderson

Tue, 29 Apr 2025 04:00:00 +0000

“HiiT meant my cortisol and lactic acid levels were through the roof”

Follow Claire on Instagram here: https://www.instagram.com/clairesanderson/?hl=en-gb

Follow Women's Health UK here: https://www.instagram.com/womenshealthuk/?hl=en

This is the Women's Health YouTube channel: https://www.youtube.com/channel/UCwGBV6mXtBB3O-rEQpevYHA

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

Co-host and producer https://fionamattesini.co.uk/

Mentioned in this episode:

In Paris they appreciate a midlife woman – Lisa Armstrong OBE

Tue, 22 Apr 2025 04:00:00 +0000

"I never really enjoyed the party scene."

Find Lisa on Instagram here: https://www.instagram.com/misslisaarmstrong/?hl=en

Find out more about Smart Works the charity here: https://www.smartworks.org.uk/

Want to book with Dr Sophie? Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

Co-host and producer https://fionamattesini.co.uk/

Mentioned in this episode:

The Beauty Triangle, entrepreneur life - and an incredible acupuncture story - Francesca Ogiermann-White

Tue, 15 Apr 2025 04:05:00 +0000

“Have a plan, but always be prepared to flex.”

Find Fran on Insta here: https://www.instagram.com/francescaogiermannwhite/?hl=en

And the Beauty Triangle is here: https://www.instagram.com/the_beauty_triangle/?hl=en

And online here: https://www.thebeautytriangle.com/

Note that Fran is not offering advice on investments and people should seek qualified advice from a financial advisor if they wish to invest in stocks, shares, property or any other investment opportunities.

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

Co-host and producer https://fionamattesini.co.uk/

Mentioned in this episode:

Navigating a new phase of womanhood - Trish Halpin

Tue, 08 Apr 2025 04:15:00 +0000

“Life is very busy, and we could have a lot of people around us, but still feel very lonely on the inside.”

Follow Trish on Insta here: https://www.instagram.com/trishoftheday/?hl=en-gb

Listen to Postcards from Midlife here via an iPhone: https://podcasts.apple.com/gb/podcast/postcards-from-midlife/id1491922331

…and here via Spotify: https://open.spotify.com/show/0fpdt9FgWiYqOq2F8ZIYcX

This is the show's private Facebook group: https://www.facebook.com/groups/681448662400206/?locale=en_GB

Here's the substack: https://fromlorraineandtrish.substack.com/

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

Co-host and producer https://fionamattesini.co.uk/

How to reinvent when life throws a curve ball - Jo Elvin

Tue, 01 Apr 2025 04:00:00 +0000

"I am the middle aged equivalent of the little girl at the swings going ‘will you play with me?"

Follow Jo on Instagram here: https://www.instagram.com/jo_elvin?igsh=MW5mMmFyazgyOW9kZw==

This is Jo’s substack: https://joelvin.substack.com/about

This is Jo’s (brilliant) podcast on fame: https://podcasts.apple.com/gb/podcast/fame-with-jo-elvin/id1659062309

This is Jo’s (also brilliant) interview with Elizabeth Day: https://podcasts.apple.com/gb/podcast/s15-bonus-episode-how-to-fail-jo-elvin-the-charity/id1407451189?i=1000587836443

This is Jo’s ultimate k-pop hero: https://www.latimes.com/entertainment-arts/music/story/2024-08-02/taemin-kpop-eternal-new-album-eternal-kcon-interview

Listen to the episode to get the full low-down on how Jo ages well – from her skincare to her supplements.

Thanks for listening to Age Well with Dr Sophie Shotter – please rate and review the show if you get a moment.

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Co-host: https://fionamattesini.co.uk/

Mentioned in this episode:

The Magic of Mushrooms - Part 1 - Tom Baxter (Bristol Fungarium)

Tue, 25 Mar 2025 05:00:00 +0000

“We know that with dementia, there’s something within lion's lane that the body is making use of.”

Follow Bristol Fungarium on Instagram here: https://www.instagram.com/bristolfungarium/

See the range (and buy / subscribe) here: https://bristolfungarium.com/

Thanks for listening to Age Well with Dr Sophie Shotter – please rate and review the show if you get a moment.

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Co-host: https://fionamattesini.co.uk/

Mentioned in this episode:

The Priorities Method - and how to figure out what it is you really want - Lily Silverton

Tue, 18 Mar 2025 05:10:00 +0000

"As a coach, I started to realise that a goal setting approach wasn't hitting the mark"

Follow Lily on Instagram here: https://www.instagram.com/lily_silverton/

Find out more about Lily here: https://lilysilverton.com/

A few things mentioned on the show follow:

Here’s the career TED talk Fiona mentioned https://www.ted.com/speakers/emilie_wapnick

This is Magic Breakfast: https://www.magicbreakfast.com/

Here’s Sophie’s brain health ep: https://podcasts.apple.com/gb/podcast/the-latest-data-on-how-to-radically-improve-your/id1713189123?i=1000672170402

Listen to the episode to get the full low-down on how Lily ages well – from her skincare to her supplements.

Thanks for listening to Age Well with Dr Sophie Shotter – please rate and review the show if you get a moment.

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Co-host: https://fionamattesini.co.uk/

Mentioned in this episode:

How we're navigating mid-life - Annabel Rivkin and Emilie McMeekan

Tue, 11 Mar 2025 05:00:00 +0000

“We had a series of dinner parties with wonderful midlife women…and the biggest connector was anxiety”

You can find Annabel and Emilie on socials here:

https://www.instagram.com/annabelrivkin/?hl=en

https://www.instagram.com/emiliemcmeekan/

Join The Midult here https://themidult.com/

Do also follow https://www.instagram.com/themidult/

This is the I’m Absolutely Fine! podcast https://podcasts.apple.com/gb/podcast/im-absolutely-fine-by-the-midult/id1437138526

… and on Spotify: https://open.spotify.com/show/01hQ1kQyzftDFFJLrPbbKo

You can buy “I'm Absolutely Fine!: A Manual for Imperfect Women” at all the usual bookshops and on all the usual channels.

Annabel and Emilie write a column in the Saturday Telegraph Magazine and Annabel has a column in the Evening Standard’s ES Magazine.

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

Co-host and producer https://fionamattesini.co.uk/

Mentioned in this episode:

Unpacking the buzz around 'deep plane' - a more natural approach to face lifts - Marc Pacifico

Tue, 04 Mar 2025 05:00:00 +0000

“With modern face lifts, you could have a result that looks more natural, looks like you, and – inevitably - lasts longer.”

Follow Marc on Instagram here: https://www.instagram.com/marcpacifico/

Find out more about Marc here: https://www.marcpacifico.co.uk/

Marc mentioned the TRIGGERnometry podcast – listen here: https://podcasts.apple.com/gb/podcast/triggernometry/id1375568988

Marc also mentioned Caroline A. Glicksman, MD and Patricia McGuire, MD – both well-regarded surgeons in the US.

Listen to the episode to get the full low-down on how Marc ages well – from his skincare to his supplements.

Thanks for listening to Age Well with Dr Sophie Shotter – please rate and review the show if you get a moment.

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Co-host: https://fionamattesini.co.uk/

Over 35 yrs in beauty... this is my routine and my must-have products - Nadine Baggott

Tue, 25 Feb 2025 05:00:00 +0000

"There's a revolution happening in skincare"

Follow Nadine on Instagram here: https://www.instagram.com/nadinebaggott/?hl=en

This is Nadine’s YouTube channel: https://www.youtube.com/c/nadinebaggott

Find out more about Nadine here: https://nadinebaggott.com/

Listen to the episode in full to find out how Nadine ages well – from her skincare to her supplements.

Thanks for listening to Age Well with Dr Sophie Shotter – please rate and review the show if you get a moment.

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Co-host: https://fionamattesini.co.uk/

I've seen data that this is transforming women's vaginal health - Dr Zoe Williams

Tue, 18 Feb 2025 05:00:00 +0000

“You will have a weakened pelvic floor whether you've given birth vaginally or via a C section.”

Follow Dr Zoe on Instagram here: https://www.instagram.com/drzoewilliams/?igsh=eHIyNXdjb2F4cXg1#

Here’s the Barnes Doula interview mentioned: https://www.thebarnesdoula.com/news/what-its-really-like-to-have-a-doula

Dr Zoe mentioned Professor Nargund at Create Fertility – more info here: https://www.createfertility.co.uk/about/meet-our-team/members/professor-geeta-nargund

Always do your research on egg freezing – further reading here: https://www.bbc.co.uk/news/uk-68505321

Information on the Issviva x Joylux device is here: https://issviva.co.uk/products/joylux-device?srsltid=AfmBOoo-PWy0PK6_qGRboOVJXbS4cuAkXr_86swk3fNtTkChXBBlspyl

On the fragrance side, Dr Zoe mentions https://www.franciskurkdjian.com/ and https://uk.thenueco.com/products/forest-lungs

There are several other episodes mentioned on this one – including:

On at-home health test kits – 29 Oct 2024 On vaginas and vulvas – 3 Sept 2024 On microdosing mushrooms – 30 July 2024 On mushrooms in skincare – 16 Jan 2024

Listen to the episode in full for more on Dr Zoe’s routine and skincare etc.

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

Co-host and producer https://fionamattesini.co.uk/

Avoiding fame, finding zen, and why I haven't seen myself in 'Love Actually' - Sienna Guillory

Tue, 11 Feb 2025 05:05:00 +0000

"I was all over the tabloids, and felt massively misquoted - and I found that hurtful."

Follow Sienna on Instagram here: https://www.instagram.com/guilloryguillorybe/?hl=en

Listen to the episode to get the full low-down on how Sienna ages well – from her skincare to her supplements.

This is Cilento, the part of Italy Sienna was referring to: https://www.embark.org/italy/naples/activity-type/adventures/cilento-and-vallo-di-diano-national-park

This is The Carrier Company https://www.carriercompany.co.uk/

The short film Sienna mentioned is called ‘I’m Here’ and is available on YouTube.

Here’s Maria Popova and The Marginalian https://www.themarginalian.org/

Thanks for listening to Age Well with Dr Sophie Shotter – please rate and review the show if you get a moment.

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Co-host: https://fionamattesini.co.uk/

I've tried every treatment / tweakment going; this is what works - Alice Hart Davis

Tue, 04 Feb 2025 05:05:00 +0000

“I get all sorts of people on Instagram saying, ‘but surely you wouldn't put that stuff on your face?’ Yeah, I do. I absolutely do.”

Follow Alice on Instagram here: https://www.instagram.com/alicehartdavis/?hl=en

This is The Tweakments Guide https://thetweakmentsguide.com/

Listen to the episode to get the full low-down on how Alice ages well – from her skincare to her supplements.

Here’s Allergan’s A-Z of medical aesthetics: https://media.allergan.com/actavis/actavis/media/general/AA_Consumer%20Lexicon%20Glossary_A4%20Landscape_22May24.pdf

Alice mentions a book, ‘Why We Sleep’ – this is by Dr Matt Walker – more here: https://www.sleepdiplomat.com/

Alice mentions a few things that Sophie covers off in other podcast episodes – here are some links:

On NAD and the Nuchido supplement: https://podcasts.apple.com/gb/podcast/we-now-have-hard-evidence-that-this-will-slow-cellular/id1713189123?i=1000665960901

On body treatments (e.g. the Body Ballancer): https://podcasts.apple.com/gb/podcast/cellulite-stretch-marks-stubborn-fat-and-loose-skin/id1713189123?i=1000651847475

On lasers, LED, IPL: https://podcasts.apple.com/gb/podcast/so-whats-the-deal-with-lasers-led-ipl/id1713189123?i=1000654001047

On at-home devices (inc. LED masks): https://podcasts.apple.com/gb/podcast/at-home-gadgets-and-devices/id1713189123?i=1000635505441

On RF micro-needling: https://podcasts.apple.com/gb/podcast/no-needle-anti-ageing-why-everyones-buzzing-about-sofwave/id1713189123?i=1000670480250

Thanks for listening to Age Well with Dr Sophie Shotter – please rate and review the show if you get a moment.

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Co-host: https://fionamattesini.co.uk/

Mentioned in this episode:

My ultimate make-up recommendations and tips – Caroline Barnes

Tue, 28 Jan 2025 05:05:00 +0000

“If you're using the right tools in the right way, it will make such a difference to your make-up.”

Find out more about Caroline at https://www.carolinebarnes.co.uk/

Follow her on Insta here: https://www.instagram.com/carolinebarnesmakeup/?hl=en

Buy Caroline’s make-up brushes here: https://otisbatterbee.com/collections/makeup-brush-sets/products/obxcb-12-piece-makeup-brush-set

Here’s Caroline’s YouTube channel: https://www.youtube.com/c/SpeedBeautybyCarolineBarnes

And here’s the episode she mentioned on facial cupping: https://www.youtube.com/watch?v=exp5TJ6iKmk

Find out more about Look Good Feel Better here: https://lookgoodfeelbetter.co.uk/?utm_source=google&utm_medium=paid&gad_source=1&gclid=Cj0KCQiAy8K8BhCZARIsAKJ8sfQdzKAYm2Umikbi9pLcg6JSyD7a184iCujhv--EZ2gKjlCHYU5WaQwaArp1EALw_wcB

Listen to the episode to get the full low-down on how Caroline ages well – and her full list of make-up tips and product recommendations.

Thanks for listening to Age Well with Dr Sophie Shotter – please rate and review the show if you get a moment.

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Co-host: https://fionamattesini.co.uk/

Mentioned in this episode:

What a beauty editor loves, uses, and rates - Rosie Green

Tue, 21 Jan 2025 05:05:00 +0000

"People always ask what gives the most bang for your buck - and it's these two"

Rosie mentions:

https://www.fionalamb.com/ - hypnotherapist and anxiety therapist

https://www.saradavison.com/ - divorce coach

Michelle Roques-O'Neil – aromatherapist and reiki practitioner – available at https://thefrenchpharmacy.co/

This is Dr Sophie’s rosacea episode, also mentioned in the episode: https://podcasts.apple.com/gb/podcast/a-run-down-on-rosacea-sensitive-skin/id1713189123?i=1000651142069

Listen to the episode to get the full low-down on how Rosie ages well – from her skincare to her supplements.

Buy Rosie’s book and find out more at https://www.lifesrosie.co.uk/

Follow Rosie on Instagram here: https://www.instagram.com/lifesrosie/

Thanks for listening to Age Well with Dr Sophie Shotter – please rate and review the show if you get a moment.

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en …and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Co-host: https://fionamattesini.co.uk/

Mentioned in this episode:

How I built a £30m brand with collagen as the hero - Maxine Laceby

Tue, 14 Jan 2025 05:00:00 +0000

"In business, I want to be the woman that wasn't there for me"

This is Sophie’s 2024 collagen episode – mentioned on the show:

On Apple: https://podcasts.apple.com/gb/podcast/dr-sophies-collagen-101/id1713189123?i=1000634725358

On Spotify: https://open.spotify.com/episode/6V7QZuHzM4K7vmRGQs6jSF?si=ZC-rtzODRTCHma0Rb8GKMA

This is Maxine’s We Are The City interview – also mentioned: https://www.youtube.com/watch?v=OtuPmFLW7AE

More on Josephine Butler here: https://www.theguardian.com/society/article/2024/jun/27/josephine-butler-the-forgotten-feminist-who-fought-the-uk-police-and-their-genital-inspections

More on Artemisia Gentileschi here: https://en.wikipedia.org/wiki/Artemisia_Gentileschi

More on Coppa Feel here https://coppafeel.org/

Listen to the episode to get the full low-down on how Maxine ages well – from her skincare to her supplements.

Get Absolute Collagen here: https://www.absolutecollagen.com/?utm_content=brand&gclsrc=aw.ds&&tw_source=google&tw_adid=727791043413&tw_campaign=18394523020&gad_source=1&gclid=Cj0KCQiAkJO8BhCGARIsAMkswyhzX1kLUTUDlNnWPgQDwqbpXgzsb5vVysRihlG-D9OmaMJTOPlUpaoaApdxEALw_wcB

Follow Maxine on Instagram here: https://www.instagram.com/maxinelaceby/

Follow Absolute Collagen too while you’re at it https://www.instagram.com/absolutecollagen/

Thanks for listening to Age Well with Dr Sophie Shotter – please rate and review the show if you get a moment.

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Co-host: https://fionamattesini.co.uk/

How yoga nidra transformed my nervous system - Victoria Woodhall

Tue, 07 Jan 2025 05:00:00 +0000

"20 minutes of yoga nidra is equivalent to two hours sleep - it's that profound"

Victoria mentions:

A Chinese medicine practitioner called Katie Brindle.

The Touch Tuina clinic in Camden.

Yeotown Wellness Retreat based in Devon.

Holy Carrot restaurant on London’s Portobello Road.

Victoria loves:

https://www.instagram.com/rantsandbigpants/?hl=en

https://www.instagram.com/ruthcrilly/?hl=en

https://www.instagram.com/drtaraswart/?hl=en

https://www.instagram.com/nicolesneuroscience/?hl=en

Listen to the episode to get the full low-down on how Victoria ages well – from her skincare to her supplements.

Find out more about Victoria and book a yoga class here: https://victoriawoodhall.com/

Follow Victoria on Instagram here: https://www.instagram.com/victoriawoodhall/?hl=en

This is Victoria’s (fabulous!) YouTube channel: https://www.youtube.com/@victoriawoodhallyoga

Thanks for listening to Age Well with Dr Sophie Shotter – please rate and review the show if you get a moment.

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Co-host: https://fionamattesini.co.uk/

Mentioned in this episode:

Skin tracking - is this the future of ageing well?

Tue, 31 Dec 2024 05:00:00 +0000

Prof. Mark Birch-Machin

This chat covers:

• A quick explainer on organelles, mitochondria, and DNA • The mitochondrial DNA and how this is different to our genetic DNA • How skin ages • The role of UV light • Sunscreen • Tracking skin damage • Lifestyle interventions • Mark’s story • Can lines and wrinkles be reversed?

Prof. Mark Birch-Machin is the founder of Skin Life Analytics and has been a professor in Molecular Dermatology for over 30 years. He's also the recipient of the prestigious Society of Cosmetic Scientists Lifetime Achievement Award.

Skin Life Analytics offers non-invasive testing that can test and track how our skin is ageing at its deepest cellular level – or as their website puts it, ‘making the invisible, visible’.

You can find out more at https://skinlifeanalytics.com/

And follow the team on Insta @skinlifeanalytics

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en …and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Co-host: https://fionamattesini.co.uk/

Slow down and breathe - with Rob Rea

Tue, 24 Dec 2024 05:00:00 +0000

The breathwork episode

Rob Rea is a world-renowned breathwork coach and his work has been featured everywhere from Vogue and Tatler to The Times.

This chat covers:

• The physical benefits of breathwork • What Rob has seen in practice • The different types of breathwork • Over-breathing and its implications • HRV and the vagus nerve • Pairing breathwork with meditation • Using breathwork to stay calm • Using breathwork to energise • Mouth taping • Contraindications • Breath holding • A breathwork journey

You can book Rob for workshops and one-on-ones – and he can also work with people online.

Go to https://www.robrea.co.uk/

Follow Rob on Instagram https://www.instagram.com/robrea__/?hl=en

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en …and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Co-host: https://fionamattesini.co.uk/

Mentioned in this episode:

Sugar + sweeteners (the latest thinking, gurus, products, and data)

Tue, 17 Dec 2024 05:00:00 +0000

Dr. Sophie Shotter

Dr. Sophie and Fiona discuss:

• Is sugar addictive? • A dummy’s explainer on insulin and blood sugar spikes • The glucose goddess - Jessie Inchauspé • What’s a glucose spike? • Robert Lustig and ‘Sugar: The Bitter Truth’ • What is sugar made of? • Glucose v fructose • Sugary drinks • Is sugar bad for our skin? • Do artificial sweeteners cause cancer? • Can sugar cause cancer? • Notes on sugar-free chocolate bars • New sugar elimination supplements • Reasons to give up sugar • Final tips

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/ Co-host: https://fionamattesini.co.uk/

Dr Sophie mentions a few studies and ideas – see below and press ‘episode website’ for the full list:

In a 2017 review published in the British Journal of Sports Medicine the authors compared sugar to being as addictive as cocaine. One study in Cologne concluded that foods high in sugar can rewire the brain to demand more in the future. It’s been proven that people eat sugary foods not just for the taste or for starchy calories but because they get a dopamine hit – which is the pleasure hormone – in other words we feel good when we eat sugar because our brains see it as a reward.

Sugar causes something called glycation which is when sugar molecules attach to fats and proteins, causing a loss of elasticity in the skin and potentially fine lines and dark spots.

We also have evidence to suggest that lowering your sugar intake can have a positive impact on your skin’s condition. Read more:

https://www.eatingwell.com/article/7869775/what-happens-to-your-body-when-you-cut-out-sugar/#:~:text=In%20fact%2C%20research%20suggests%20that,lots%20of%20fruits%20and%20vegetables.

Sophie mentioned SkinCeuticals A.G.E Interrupter Advanced

Last year, the World Health Organization (WHO) issued a statement to say that the artificial sweetener aspartame is “possibly carcinogenic to humans” and it’s now calling for further research. The research was done by The International Agency for Research on Cancer which is part of the World Health Organization.

In 2022 the BMJ published the findings of a study that took place in Paris that concluded all artificial sweeteners are linked to an increased risk of heart disease and “should not be considered a healthy and safe alternative to sugar.”

Evidence suggests that our liver can metabolise 6 teaspoons (or 12g) of sugar a day. Anything above that will cause problems…most people consume around 100g of sugar a day.

We also have data suggesting that high sugar is the main driver in ADD and ADHD.

Sophie mentioned Zotter which you can get from the Cocoa Runners website: https://cocoarunners.com/shop/zotter-70-milk-chocolate-dark-style/

She also mentioned the STC range of chocolate.

BioLumen have launched a product called Monch Monch - a plant-based fibre powder that you mix with water and this is designed to expand in the stomach like a sponge and soak up any sugar in food, so it can’t be absorbed. The idea is that, once it’s locked in the “sponge”, a significant amount of the sugar will simply pass through the digestive tract. It can apparently absorb six grams of sugar.

Researchers at Harvard have been working in collaboration with Kraft Heinz on a process that takes a plant-based enzyme that has the ability to convert sugar to fibre in the gut.

A UK startup called Zya is doing something similar.

Mentioned in this episode:

Sure, give up caffeine – but not coffee. Here’s why.

Tue, 10 Dec 2024 05:00:00 +0000

Dr. Sophie Shotter

Dr. Sophie and Fiona discuss:

• Why are some experts suddenly saying that coffee is healthy? • What about caffeine? • The healthiest way to drink coffee • Is there a case for giving up caffeine? • How is decaf made / the filtration systems to look out for • Decaf brand thoughts and recommendations • Half caf coffee • Can you drink too much coffee? • Is coffee addictive? • Does adding milk change the health benefits?

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Co-host: https://fionamattesini.co.uk/

Dr Sophie and Fiona mention the Decadent Decaf Coffee Company. Find out more here:

https://www.decadentdecaf.com/

The caffeine sensitivity test Sophie mentioned is here:

https://www.reachforhealth.co.uk/dnafit/

Sophie mentioned a study at the University of Gothenburg and Professor Dag Thelle.

In 2017 the British Medical Journal published a study that looked at over 200 meta-analyses of the health benefits of coffee and that found drinking three to fours cups of black coffee a day provides the most health benefits overall. These included lowering the risk of heart disease; numerous types of cancer; and neurological, metabolic and liver disorders; as well as overall mortality. Other studies have found coffee reduces the risk for melanoma, heart disease, multiple sclerosis, type 2 diabetes, liver disease, prostate cancer, Alzheimer’s.

Some smaller studies have shown caffeine can cause dyspepsia, which is poor digestion – plus heartburn and nausea.

One study found that people who consumed more caffeine had a higher risk of IBS, especially women and people who were overweight or obese.

Caffeine can increase gastric acid production, which can contribute to GERD.

Bath oils | PJs | CBD | candles | hair | make-up | skincare > Dr Sophie's favourite things

Tue, 03 Dec 2024 05:00:00 +0000

The Christmas Gift Guide

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/ Co-host: https://fionamattesini.co.uk/

Here’s Dr Sophie’s list of favourite things (press ‘episode website’ for the full list):

Clinical Skin - gentle cream cleanser Revision’s cleansers Romilly Wilde’s Light + Energy balm cleanser Revision DEJ daily boosting serum – and eye creams (esp the DEJ) and Body Firm Meder Beauty skincare – Salva hand and Circa hand creams Meder Beauty Circa Night Cream HA Immerse and the Restorative Skin Complex from Elastin Skinbetter Science - AlphaRet Overnight Cream Clinical Skin’s rejuvenating eye balm Clinical Skin’s polypeptide firming serum, and collagen boosting moisturiser Intradermology Synergy 6 sunscreen Neova Silc Sheer sunscreen Murad’s clear SPF sunscreen Meder Beauty sheet masks – the full range – esp the Hydra-Fill and Enzy-Peel Exuviance’s peel pads AP25 Pureology for hair K18 for hair Act+Acre for hair GLOV hair towel Sweaty Betty gym wear Panache sports bras Tumi luggage The N101 supplement from Dr Nathan Bryant Earth Resonance’s lion’s mane Dreem Distillery CBD oil EverNutri supplements Nuchido Time+ (NAD) Clear Whey Protein from FoodSpring – esp the Raspberry Mojito flavour Victoria Beckham eye liners Pat McGrath eye shadows Natasha Denona eye shadows Chantecaille Cheek Gelée and their Longest Lash Mascara Giorgio Armani's Luminous Silk Foundation Oxygenetics concealer Hourglass’s Voyeur Waterproof Liquid Eyeliner Revision’s Youthful Lip Replenisher (tinted) Augustinus Bader tinted lip balm Clarins – tinted shea butter lip balm Dyson Air Straight Thomas Kosmala Après l'Amour Chanel Coromandel Aqua Allegoria Pera Granita by Guerlain Baccarat Rouge 540 fragrance 8Sleep mattress Oura Ring – device Sensate – device Apollo wristband – device Nurosym – device Rowland Earthing grounding sheet HigherDose Infrared PEMF mat Dermalux flex Emerald Laser Body Ballancer Loop Earplugs Respire mouth taping Eberjey nightwear Yves Delormes bed linen Olverum bath oil De Mamiel bath salts L’Occitane Shea Butter bath soak Shower cap by Kitsch Luxe Drowsy Sleep Mask AirPods Max The Bertioli Water Meadow Breathing Balm Dipytique candles Jo Malone candles Neom candles Nike MetCon trainers APL trainers Freddie’s Flowers FLOWERBX Perrier Jouet champagne Truth Coffee Lo Bros kombucha 1 Living kombucha Sophie also loves her Stanley Cup Dr Joe Dispenza - Becoming supernatural (book) and The Source (doc) Maria Tash's ear jewellery Jo Malone’s soaps - English Pear and Freesia is Sophie’s current fave

Mentioned in this episode:

Meet Prof David Nutt and find out how cannabis is radically changing lives

Tue, 26 Nov 2024 05:00:00 +0000

The medicinal cannabis episode

In the UK, cannabis is illegal for recreational use and is classified as a Class B drug.

Dr Sophie is not endorsing recreational drug use – and people should chat to their GP for guidance on any disease or disorder.

Dr. Sophie and Prof David discuss:

• Alfie Dingley’s story • Cannabis and multiple sclerosis • Cannabis and cancer • CBD / THC ratios • Cannabis and glaucoma • Funding and studies • Getting a UK prescription • Supply chain • GP training • Dosing • The T21 Clinic • Risks and side effects • The financial discussion • Big pharma • Costs • Support and guidance

Here’s are some links to David’s book “Cannabis (seeing through the smoke): The New Science of Cannabis and Your Health”

https://www.yellowkitebooks.co.uk/titles/professor-david-nutt/cannabis-seeing-through-the-smoke/9781529360509/

https://www.amazon.co.uk/Cannabis-seeing-through-smoke-Science/dp/1529360498/ref=tmm_hrd_swatch_0?_encoding=UTF8&qid=&sr=

TIMES review https://www.thetimes.com/article/cannabis-seeing-through-the-smoke-by-david-nutt-review-bmxrws3n8

Here’s the Drug Science website:

https://www.drugscience.org.uk/

Follow Prof David on Twitter / X here: https://x.com/ProfDavidNutt?ref_src=twsrc%5Egoogle%7Ctwcamp%5Eserp%7Ctwgr%5Eauthor

Follow / listen to the Drug Science podcast here: https://podcasts.apple.com/gb/podcast/the-drug-science-podcast/id1474603382

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

Find out more by heading to https://drsophieshotter.com/

This podcast was produced by https://thepodcastpeople.co/

Co-host: https://fionamattesini.co.uk/

Mentioned in this episode:

Meet Nick Birch and find out why women need to take their bone health way more seriously

Tue, 19 Nov 2024 05:00:00 +0000

The bone health episode

Nick Birch is a Consultant Spine and Bone Health Specialist and the founder of Osteoscan UK - the first company in Britain to offer access to bone mineral density and bone fragility measurement using REMS technology.

Find out more and book an appointment with Nick via https://www.osteoscanuk.com/

Dr. Sophie and Nick discuss:

• Why bones are integral to our health and wellbeing • Bone loss at peri / post menopause • Osteoporosis as a silent / hormone related disease • Oestrogen receptors • HRT as a treatment for osteoporosis • Bisphosphonates • Bone elasticity • Fractures • DEXA scans v REMS screening • GP resistance to refer for scans • How we can empower ourselves • Vitamin D (‘hormone’ D) • Diet • Exercise • The calcium question • HRT again – inc. for women unable to take it • Medication options • Support • Can you reverse osteoporosis?

Nick mentioned:

https://www.drlouisenewson.co.uk/

frax.shef.ac.uk/FRAX/

An APPG report which is here https://strwebprdmedia.blob.core.windows.net/media/mfql3b50/appg-on-osteoporosis-and-bone-health-inquiry-report-into-primary-care-2022.pdf

Prof Belinda Beck’s programme which is here https://theboneclinic.com.au/onero/

The moringa leaf – more info here https://www.webmd.com/vitamins-and-supplements/health-benefits-moringa

An analysis by Paola pasani and her team, published in 2023 – read more here https://pubmed.ncbi.nlm.nih.gov/36752950/

Doug Lucas, and his patients who've reversed their osteoporosis – read more here https://www.optimalhumanhealth.com/

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Co-host: https://fionamattesini.co.uk/

Mentioned in this episode:

Meet Smita Sinha and find out how she's transforming women's vaginal and vulval health

Tue, 12 Nov 2024 05:00:00 +0000

The gynaecology episode

Dr. Sophie and Miss Smita discuss:

• Vulval and vaginal skin conditions – an explainers • The BTL Emsella chair for pelvic floor strength • The BTL EmFemme 360 radio frequency device • Pelvic floor lifts – exactly how to do them • Vaginal polynucleotides • Vaginal and vulval skincare protocols – and why this is needed • Chronic UTIs • Vaginal and vulval exams

Find out more about Smita here:

https://www.serenitywomensclinic.co.uk/

Follow Smita on Instagram here: https://www.instagram.com/miss_smitasinha/

Follow the Serenity Clinic on Instagram here: https://www.instagram.com/serenity.womensclinic/

Smita works from Somerset and London.

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

Find out more by heading to https://drsophieshotter.com/

This podcast was produced by https://thepodcastpeople.co/

Co-host: https://fionamattesini.co.uk/

Mentioned in this episode:

Meet Dr Bita Fox and find out why her work on oral health has become so important

Tue, 05 Nov 2024 05:00:00 +0000

The holistic dentistry episode

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

Dr Bita Fox runs Munro Hall, a holistic dentist practice in Weybridge, Surrey.

Munro Hall offers a full suite of dental care spanning a range of holistic alternatives but also a range of conventional treatments including cosmetic dentistry.

You can find out more via https://weybridgebiodentist.co.uk/

Follow Munro Hall here https://www.instagram.com/munrohallclinic/?hl=en-gb on Instagram

Co-host and producer https://fionamattesini.co.uk/

Mentioned in this episode:

A review of at-home health test kits

Tue, 29 Oct 2024 05:00:00 +0000

Dr. Sophie Shotter

Dr. Sophie and Fiona discuss:

• The GlycanAge test • What are glycans? • Nuchido NAD+ and how this decreases biological age • Thriva health testing • Blood collection / pin prick tests • Gary Brecka • Body Fabulous testing (and genetic tests) • The MTHFR gene • The COMT gene • Methylation / the MTHFR mutation / B9 (folate) and B12 • How to manage the MTHFR mutation • Sure Screen Health microbiome / gut health testing • ZOE • Sure Screen Health omega 3 testing • The DUTCH test • Medichecks • Trucheck Intelli cancer markers in-clinic test • Health anxiety • Long-term health tracking vs. one-off health checks • Other at-home test kits • NHS test kits inc. bowel health tests

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/ Co-host: https://fionamattesini.co.uk/

Dr Sophie mentions a few studies and ideas – see below and press ‘episode website’ for the full list.

Note that Dr Sophie and Fiona’s experiences and decision-making was personal to them and any advice was personal to them – for example, not everyone should up the dose of any supplements such as magnesium.

With all testing, note that physical symptoms don’t always match test results – e.g. inflammation in the digestive system might show up in a calprotectin test ahead of any physical symptoms.

If you’re having oestradiol testing, please note the sensitivity and specificity around this kind of testing – e.g. certain herbs can impact the results.

If you have any symptoms or worries, your GP should always be your first port of call.

Dr Sophie references a Guardian podcast episode on home test kits with the health journalist Emma Wilkinson.

Dr Sophie also mentioned a range of other health test providers including:

Smart Nutrition

Lloyds Pharmacy

Forth

Manual

Vitall

The Chuckling Goat Microbiome Test – designed in partnership with scientists at Cambridge Genomics at Cambridge University.

Let’s Get Checked – which does a test to tell women how many eggs they have left in their ovaries by testing the anti-Müllerian hormone.

Tesco’s at-home HIV test kit.

The NHS makes use of at-home tests – for example they send out bowel cancer screening home test kits to everyone over 50. It also now offers at-home HPV tests as part of their cervical screening programme. You’ll also often see home-test chlamydia kits within many surgeries.

Is tap water ok? + water filters explained + the buzz around 'wellness water'

Tue, 22 Oct 2024 04:00:00 +0000

Dr Sophie Shotter

Dr. Sophie and Fiona discuss:

• Media stories about water quality in the UK • An idiot’s guide to how tap water is cleaned • The chemicals water boards use to clean and filter water • Chlorine • Fluoride • The issue with microplastics and nanoplastics • BPA (bisphenol A) • ‘Forever chemicals’ - phthalates / PFAS • Drugs and chemicals that make their way into the water system • Pesticides and herbicides and their impact on health • Chemical fertilisers and their impact on health • Heavy metals and their impact on health • How to filter our water effectively • Retaining water’s calcium, magnesium, and potassium • The process of remineralising • Reverse osmosis filters • Alkaline water filters • Activated carbon filters • Different brands and recommendations • Wellness water • Hydrogen water – is there any data? • What’s hard water? • Understanding bottled water • Re-usable / non plastic water bottles • Travel water bottles / drinking water abroad • Tips, advice • Water testing kits

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/ Co-host: https://fionamattesini.co.uk/

Dr Sophie mentions a few studies and ideas – see below and press ‘episode website’ for the full list:

Most UK water companies use chlorine or chloramine (a compound of chlorine and ammonia) as a disinfectant. While chlorine does disinfect water, it can also react with various organic matter in the water and this forms these disinfection by-products such as trihalomethanes, and these have been linked to various health concerns. Read more here: https://jech.bmj.com/content/57/3/166

Excess amounts fluoride has been linked to arthritis, bone damage, osteoporosis, muscular damage, fatigue, and joint-related problems. Read more here: https://pubmed.ncbi.nlm.nih.gov/34597567/

The World Health Organisation has regulated 1.5mg fluoride per litre as the upper limit.

BPA, phthalates and PFAs can mimic human hormones, and exposure to these has been shown to increase the risk of cancer, thyroid disease, autoimmune conditions and fertility problems.

Dr Sophie mentioned:

Tracey Woodruff, a microplastic researcher
Evolve, a 'plastic negative' beauty brand
The Prevented Ocean Plastic (POP) scheme

37% of water courses tested in England and Wales contain medium or high-risk levels of two types of forever chemicals. Read more here: https://www.rsc.org/policy-evidence-campaigns/environmental-sustainability/sustainability-reports-surveys-and-campaigns/cleaning-up-uk-drinking-water/

Tests in London showed levels of PFAS at 1.4 times the maximum limit. Read more here: https://www.independent.co.uk/news/uk/home-news/london-tap-contaminated-chemicals-b2514829.html

Here’s the interactive map so people can check for PFAS levels in their area: https://www.envirotech-online.com/news/pfas-analysis/105/international-environmental-technology/take-a-look-at-this-map-of-pfas-pollution-across-the-uk-and-europe/59840

Researchers from Jinan University in China have discovered that boiling water then filtering it with a coffee filter was able to remove almost 90% of harmful plastics.

Dr Sophie mentioned various systems including:

https://www.uk-water-filters.co.uk/products/reverse_osmosis_system_with_pump

The Aqua system or the Phox system

https://healf.com/collections/aarke

The British Berkefeld Water Filter system

Water2

Brita

The Jolie Filtered Showerhead

Aquathin's Whole Home Filtration system

Here’s one article with reviews: https://www.standard.co.uk/shopping/esbest/home-garden/kitchen/best-under-sink-water-filters-b1160992.html

Harvey Water Softeners have good reviews.

Hydrogen water is said to decrease inflammation, boost athletic performance, and even potentially slows the ageing process. But research is very limited. Try Hydro Water as a brand.

Here’s a review on re-usable water bottles:

https://www.gq-magazine.co.uk/gallery/best-reusable-water-bottles

Dr Sophie uses a Stanley Cup.

Dr Sophie mentioned Grayl travel bottles as well as the Sawyer Mini.

Dr Sophie mentioned the drinking water inspectorate website – and mentioned you can also view the water quality for your area via your water board’s website.

Mentioned in this episode:

Infrared explained

Tue, 15 Oct 2024 04:05:00 +0000

Dr. Sophie Shotter

Dr. Sophie and Fiona discuss:

• What is infrared? • What’s the difference between a regular sauna and an infrared sauna? • Infrared’s benefits • Data and research • Infrared sauna blankets • Infrared mats • Brands to look out for • PEMF mats • The use of EMFs • Infrared sauna blanket protocols • Tips and final thoughts

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/ Co-host: https://fionamattesini.co.uk/

Dr Sophie mentions a few studies and ideas – see below and press ‘episode website’ for the full list:

There’s some research on infrared saunas but it’s limited. This could be because infrared saunas are still quite new. It’s also been studied in very small sample sizes – but it’s found comparable benefits to traditional saunas, including for people with heart disease and chronic heart failure, plus recovery from strength training and relief of pain and stiffness in patients with rheumatoid arthritis. These studies are linked in below.

https://www.sciencedirect.com/science/article/pii/S0735109701018241?via%3Dihub

https://pubmed.ncbi.nlm.nih.gov/27001189/

https://www.scitechnol.com/peer-review/effects-of-far-infrared-heat-on-recovery-in-power-athletes-iTXW.php?article_id=3736

https://go.skimresources.com/?id=114047X1572903&url=https%3A%2F%2Flink.springer.com%2Farticle%2F10.1007%2Fs10067-008-0977-

There’s some research that suggests that PEMF devices can help repair and improve cellular function2 and it’s becoming popular to treat pain by reducing inflammation. See study here: https://www.sciencedirect.com/topics/medicine-and-dentistry/pulsed-electromagnetic-field-therapy

Mentioned in this episode:

The latest data on how to radically improve your brain health (inc. 'menopause brain')

Tue, 08 Oct 2024 04:05:00 +0000

Dr. Sophie Shotter

Dr. Sophie and Fiona discuss:

• How we can tell if our brain function is starting to decline • Emerging data on the critical role of exercise • The impact of learning new things • The role of stress • The impact of how we sleep – and how we wake up • Smart phones and digital dementia • The role of hearing loss • The role of oral bacteria • Eyesight and visual ‘gyms’ • Intermittent fasting • Nitric oxide and breathwork • Is day-dreaming good for brain health? • Relaxation anxiety / the inability to switch off • At what age should people think about their brain health? • Brain changes in peri-menopause and menopause
• A deep dive into supplements that claim to support brain health • Nootropics and off-licence drugs • Coffee / caffeine • The brain and water • Alcohol • Diet • Are there ways we can measure our brain health? • Brain training games

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/ Co-host: https://fionamattesini.co.uk/

Dr Sophie mentions a few studies and ideas – see below and press ‘episode website’ for the full list:

One study showed the pandemic led to an acceleration in memory loss and cognitive decline among the over-50s, regardless of whether or not they’d caught COVID – and the researchers have suggested that the depression, loneliness, increased alcohol use and reduced exercise (all during lockdowns) are the reason why.

A study called the MacArthur Studies of Successful Aging showed that, on average, certain lifestyle habits are more important than genetics in determining how well and how long we live – including brain health.

A study between the University of California and the University of British Columbia in 2022 showed that exercise, later in life, seems to protect the brain synapses where memories are made.

In the UK, a study of nearly 80,000 people found that the risk of dementia was halved in people who did 10,000 steps a day.

According to Dr. Damian Bailey, squats are the best exercise to boost your brain health.

A BBC journalist used meditation as part of an experiment to positively re-wire her brain – find out more here https://www.bbc.com/future/article/20230912-how-i-hacked-my-brain

Dr Sophie mentions Dr Matt Walker’s ‘Why We Sleep’

Dr Sophie mentions Jim Kwik and digital dementia. This is a phenomenon where we're outsourcing our memory to our devices.

Research shows that deep, intellectual thinking (as opposed to multitasking) activates the prefrontal cortex in a very positive way with reduced distraction and better concentration.

Some researchers have said hearing loss accounts for about 8% of dementia. With hearing loss, the temporal lobes, which focus on sound processing, emotions and memories seem to shrink.

A recent study in the US found that people with gum disease and mouth infections were more likely to develop Alzheimer’s, the most common cause of dementia. So work is now under way to check whether certain bacteria such as Porphyromonas gingivalis can cause or accelerate dementia.

Fiona mentioned Dr Dale Bredesen’s book, The End of Alzheimer’s.

Intermittent fasting might improve cognitive function by increasing the production of brain-derived neurotrophic factor (BDNF), which promotes the growth and survival of brain cells.

Nasal breathing can stimulate the production of nitric oxide, which improves blood flow and oxygen delivery to the brain. Dr Sophie mentioned the episode over the summer with Dr Nathan Bryan which talks more about this.

Researchers at Pennsylvania State University have been studying the concepts of “relaxation anxiety” and “relaxation sensitivity,” which relates to the discomfort some people feel when they slow down.

In 2020, 28 world leading experts published a major report called the Lancet Commission on dementia – and this identified a dozen “potentially modifiable” factors that affect our risk of developing dementia – including, for children, using their brains at school. This creates what researchers call cognitive reserve and resilience. So if you build up brain capacity early in life that may be a shield against future damage. In midlife, the key factors were not having too much alcohol and controlling blood pressure. In later life, not smoking, exercising regularly and keeping socially engaged all come into play.

Dr Lisa Mosconi looks at women’s brains during peri-menopause and how changes peak in the 3-7 years before and after menopause – but, for most women, their brain function does then revert back to its normal baseline.

Research shows that eating fish only once a week is associated with a 70% reduced risk of Alzheimer’s.

Studies have found an association between higher intake of fish and a lower risk of cognitive decline BUT omega-3 supplements haven't shown the same effect. So any brain health benefit seems to come from actually eating fish rather than taking fish oil supplements.

Dr Sophie mentioned the Ginkgo Evaluation of Memory (GEM) study – and the results found that ginkgo biloba did NOT lower the overall rate of developing dementia. The Queensland Brain Institute is supporting a study on lion’s mane and memory and it appears promising but we do need more evidence. Bear in mind, lion’s mane can interfere with the body’s blood clotting abilities so it should be avoided in people preparing for surgery or who take blood thinning medications.

L-theanine, particularly in combination with caffeine, is one of the more studied natural nootropics for brain health. There are a few studies that suggest it can improve attention, memory and distraction levels. The combination of L-theanine and the caffeine in green tea seems to be key.

In 2019, the Global Council on Brain Health suggested that no supplement could help brain health but they did concede that a lack of vitamins B9 and B12 appear to be linked to problems with cognitive function and brain health.

Vitamin D deficiency is linked to dementia, depression, autism and schizophrenia. Note that long term vitamin D supplementation can create high calcium levels in the blood and this can block blood vessels or cause kidney stones. So try and ensure you get your vitamin D levels checked from time to time so you’re supplementing for the right reasons and in the right way.

Resveratrol is an antioxidant polyphenol – you’ll find it in things like grapes and red wine. Some studies show it could prevent deterioration of the hippocampus, an important part of the brain associated with memory. But the jury’s still out. Bear in mind, like lion’s mane, resveratrol can also slow blood clotting.

Theobromine is a natural stimulant found in chocolate. While animal and in vitro studies suggest it may be effective at enhancing cognitive performance by improving blood flow to the brain, much more research is needed.

In a 2021 study, with 12 weeks of probiotics, brain function improved. Again, we need more studies.

There are several studies suggesting low magnesium is associated with higher risk of cognitive impairment and dementia. But as always, more quality research is needed.

Emerging research suggests ashwagandha may help improve cognitive function. In one small but well-regarded 2017 study in the Journal of Dietary Supplements, those taking ashwagandha experienced significant improvements in memory and general cognitive function. NOTE: since recording this podcast there have been concerns around ashwagandha – e.g. Denmark has now banned ashwagandha because of its potential negative impacts on hormones and its ability to induce abortion. We know that its long-term safety isn’t known, and large doses could lead to gastrointestinal issues or, rarely, liver problems.

Some people take phosphatidylserine (PS) a type of lipid found in brain tissue. Studies suggest supplementing with PS can help protect brain health, lower the risk of diseases like Alzheimer’s and Parkinson’s disease, and improve cognitive function by reducing inflammation in the brain.

According to a 2022 research, creatine might aid recovery from concussion and mild traumatic brain injury, ease symptoms of depression, improve cognition and help protect against neurodegenerative diseases. However it’s important to stick to the recommended dosages as taking too much creatine at once can cause damage to the liver or kidneys.

Animal studies have shown that Noopept speeds up how quickly the brain forms and retrieves memories by boosting a compound that promotes the growth of brain cells. But a lot more studies are needed.

During the 1970s, a few studies suggested that piracetam may improve memory in healthy adults, but these were very small studies that some people have questioned in terms of how the studies were done.

Modafinil’s stimulating effects are similar to those of amphetamines and it’s said to enhance executive functioning.

Adderall is a prescription medication that contains highly stimulating amphetamines. It’s most commonly prescribed to treat attention deficit hyperactivity disorder (ADHD) and narcolepsy, but it’s increasingly taken by healthy adults to improve attention and focus. Apparently its very popular with students. Adderall works by increasing the availability of the brain chemicals dopamine and noradrenaline within your prefrontal cortex, an area of your brain that controls working memory, attention and behaviour. The amphetamines found in Adderall also make people feel more awake, attentive and optimistic. They also reduce appetite.

But these are all prescription drugs for a reason and they do have side effects. Never take anything without consulting your GP.

A 2016 research review in the journal Practical Neurology suggests caffeine can increase alertness, improve concentration and help alleviate depression. The study also suggested a reduced risk of cognitive decline and Alzheimer’s disease. BUT too much caffeine can cause insomnia and heart palpitations.

About 73% of the brain and central nervous system is made up of water – and hydration is key for allowing nutrients into the brain and for toxins to get out of the brain.

A recent meta-analysis of studies, involving nearly 35,000 people, found that strict adherence to the Mediterranean diet was associated with a 21% lower risk of cognitive disorders and a 40% lower risk of Alzheimer’s.

Another study showed that Alzheimer’s in Japan increased from 1% in 1985 to 8% in 2008 and cited the increased consumption of a western-style diet as the cause. What low-dementia rate nations have in common is a moderate intake of fish and seafood, plenty of vegetables and beans, fermented foods.

Dr Sophie mentions the Alzheimer’s prevention clinic in New York.

One study found that just a few days on a high ultra processed food diet caused damage to the hippocampus – linking this to reduced memory. Though we are still in the early days of this research, evidence is showing that higher consumption of ultra processed food is linked to increased risk of depression and harmful changes in the regions of the brain linked to learning and memory.

Dr Sophie mentions the Protect study run by the University of Exeter and Kings College, in partnership with the NHS. https://www.protectstudy.org.uk/

Dr Sophie mentions WAVi, a brain measurement platform developed by doctor with a background in astrophysics.

More studies and sources here:

https://www.thelancet.com/journals/lanhl/article/PIIS2666-7568(23)00187-3/fulltext

https://jamanetwork.com/journals/jamaneurology/fullarticle/2795819

https://www.theguardian.com/society/2023/nov/01/brain-health-six-key-questions-answered#:~:text=%E2%80%9CThe%20best%20ways%20to%20protect,social%20interaction%2C%E2%80%9D%20says%20Corbett.

https://www.bbc.co.uk/programmes/articles/2gjGgWygH4G8nS0VSJ0D72G/eight-ways-to-boost-your-brain-power#:~:text=Exercise%20makes%20your%20brain%20bigger,and%20removing%20any%20nasty%20toxins.

https://www.forbes.com/sites/jesscording/2024/03/18/brain-experts-share-whats-killing-your-focus-and-what-to-do-about-it/

Mentioned in this episode:

Cold water therapy (and how it's transforming menopausal mood swings, anxiety, and hot flushes)

Tue, 01 Oct 2024 04:00:00 +0000

Dr. Sophie Shotter

Dr. Sophie and Fiona discuss:

• Do the claims match the data? • What is cold therapy? • Hormetic stress – an explainer • The mental health benefits • Cold-water therapy, the menopause and menstrual symptoms • Wim Hof – the protocol, the claims, and the science • Tips for wild swimming • DIY plunge pools • Ice bath and cold shower protocols • The risks associated with cold water therapy • A documentary, a book, and a TV series

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

Co-host and producer https://fionamattesini.co.uk/

Dr. Sophie mentions…

This study linking hormetic stress and longevity: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7520385/

It’s been shown that the shock of cold water can stimulate the blood cells that fight off infection (leukocytes). One Dutch study for example found that people who took a daily cold shower (after a warm shower) had nearly a third fewer days off work ‘sick’ than those who had a warm shower only.

Prof Mike Tipton found that people who went outdoor swimming suffered fewer respiratory tract infections than their partners, who were not swimmers. But the same benefits were also seen in people who went swimming indoors. So he said this points to the swimming being the beneficial thing rather than the extreme cold.

Sophie mentioned the writer Tim Clare who said in a newspaper article that cold water therapy healed him from panic attacks.

Sophie mentioned Dr Mark Harper, the author of a book called “Chill: The Cold Water Swim Cure.” Dr Harper says we have preliminary evidence that regular cold-water swimming or bathing reduces inflammation, reduces the stress response, and has positive effects on mood and inflammatory-related conditions such as fibromyalgia, Crohn’s, and arthritis.

Prof Mike Tipton says his lab oversaw cold water immersion sessions for a woman with severe depression who credited these sessions for her recovery.

A study from University College London led by Prof Joyce Harper found that swimming in cold water can “significantly reduce symptoms of the menopause such as mood swings and hot flushes.” It worked with over a thousand women aged 16-80, with an average age of 49. Among the study group, 785 women were going through the menopause at the time. Half the women said cold-water swimming significantly reduced their anxiety, while large minorities said it also helped tackle mood swings, low mood, and hot flushes. More than 60% said they swam specifically to address menopausal symptoms.

Professor Peter Pickkers found Wim Hof’s cold water and breathwork protocol created major changes in levels of oxygen and CO2 plus an increase in adrenaline to extremely high levels. It’s thought that this super high adrenaline resulted in the production of an anti-inflammatory cytokine called IL-10 (a cytokine is a protein that acts as a chemical messenger in the body’s immune system to control the growth and activity of other cells).

Sophie mentioned the Safer Seas Service app created by Surfers Against Sewage.

Sophie reinforced the findings of Prof Greg Whyte of Liverpool John Moores University…safety is paramount.

The British Heart Foundation has said people with heart conditions should check with medical professionals before using cold water therapy.

Surfers Against Sewage have published a safety guide – as has The Outdoor Swimming Society.

Sophie mentioned a documentary called The Ponds.

Fiona mentioned the book ‘Waterlog’ by Roger Deakin and a BBC series with Alice Roberts who wild swam across the UK.

Mentioned in this episode:

No-needle anti-ageing? Why everyone's buzzing about Sofwave (+ the lowdown on other in-clinic 'energy' devices)

Tue, 24 Sep 2024 04:05:00 +0000

Dr. Sophie Shotter

Dr. Sophie and Fiona discuss:

• Radio frequency (RF) • Radio frequency brands • Radio frequency microneedling • Why RF microneedling is more powerful than RF alone • Evolving with the latest tech • Ultrasound, HIFEM and EMS • Why Sofwave is different [as an ultrasound device] • Plasma devices • Sofwave clinical data • How Sofwave works • Sofwave’s safety profile • Who Sofwave’s best suited for • Collagen • What Sofwave wont deal with • What a Sofwave treatment is like • Sofwave downtime post treatment • Sofwave results • Combining Sofwave with other treatments • So which energy device treatment is best? • The devices Dr Sophie is excited by

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

Co-host https://fionamattesini.co.uk/

Produced by https://thepodcastpeople.co/

Dr Sophie mentions:

Thermage radiofrequency

The Venus range

Exilis radiofrequency with ultrasound

Profound RF

Morpheus 8

Secret RF by Cutera

The Profound Matrix by Candela – a device that’s coming to the UK imminently

Emsculpt; Emsculpt Neo; and Emface

Plaxar Plasma Pen

NeoGen plasma

NeoGen is what Shirley Ballas had – read (and see more) here https://www.getthegloss.com/beauty/shirley-ballas-non-surgical-facelift-neogen-plasma

AgeJET plasma

The Emerald laser

The Resonic device which uses high-frequency sound waves, designed to improve the appearance of cellulite

The Cellfina System, designed to improve the appearance of cellulite

The Body Balancer device

The Venus legacy skin contouring and tightening device

Sofwave has been cleared by the FDA for lifting the eyebrows; the submentum (the area under the chin); the neck – plus for acne scarring, and for improving the appearance of cellulite. On clinical studies, the average eyebrow lift achieved was 3-4 millimetres.

Mentioned in this episode:

Skin peels - how they've evolved and why they're still an 'A' lister's favourite, in-clinic

Tue, 17 Sep 2024 04:00:00 +0000

Dr. Sophie Shotter

Dr Sophie and Fiona discuss:

• What is a skin / chemical peel? • Types of chemical exfoliants • What peels can treat • An explainer on the different types of peel • Can they damage the skin? • What happens during a treatment • Do’s and Dont’s • What to expect after treatment • How often does Sophie recommend people have a peel? • The difference between a chemical peel and microdermabrasion • Would it ever be appropriate for a younger teen to have a peel? • Can you have a skin peel on the body? • Advice and recommendations on at-home skin peel kits • Skin peels and the skin’s microbiome • Enzyme peels

Dr Sophie mentions:

Skin Better Science’s AlphaRet peel pads
Neostrata’s peel pads - either PHA or glycolic acid
Neo Strata’s Citriate peel pads
Exuviance’s peel pads
Oxygenetix post procedure foundation

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

Co-host https://fionamattesini.co.uk/

Produced by https://thepodcastpeople.co/

Mentioned in this episode:

Fake tan for grown-ups (how to keep that summer glow going + loads of new tips)

Tue, 10 Sep 2024 04:05:00 +0000

Dr Sophie Shotter

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

Co-host and producer https://fionamattesini.co.uk/

Several brands and products were mentioned in this episode – here they all are:

The James Read range. The Amanda Harrington range. The Tan Luxe range. St Tropez’s Express Bronzing Mousse. Bare by Vogue. Sunny Honey Bali Bronzing Foam. Bondi Sands Technocolor 1 Hour Express Self Tanning Foam. Ultra Violette’s Queen Screen SPF50 Glow Drops. Isle of Paradise self tan drops. The Saltyface range. Butter by Tan-Luxe. Isle of Paradise's Self-Tanning Butter. James Read H20 Tan Mist. The Skinny Tan Dual Tanning Mitt.
Skinny Tan Coconut Water Tanning Mist - this doesn’t have a colour guide which is the bit that can sometimes stick in those little post-shave dots. Amanda Harrington’s Body Base Pre-Colour Primer. The Bondi Sands Back Applicator.
Isle of Paradise's Hyglo Hyaluronic Self-Tan Serum for Face. James Read's Glow20 Facial Tanning Serum. St Tropez's Self Tan Purity Bronzing Water Face Mist. Amanda Harrington’s Face Buffer Brush. Skinny Tan Dry Mist Finishing Spray.
Skinny Tan Gradual Tanner. Soap & Glory Sugar Crush Body Scrub Lusso Tan's Bath Bomb. Isle of Paradise's Over-It Remover. The St.Tropez Tan Remover & Primer Mousse. Bondi Sands Self Tan Eraser. The Rose & Caramel Purity Excel 60 Second Self Tan Removing Scrub. Tan-Luxe Glyco Water Self-Tan Eraser Exfoliating Tan Remover & Primer. The Institut Esthederm suncare range.

Mentioned in this episode:

The vaginas + vulvas episode

Tue, 03 Sep 2024 04:05:00 +0000

Dr. Sophie Shotter

Dr Sophie and Fiona discuss:

• The education gap with female genitalia • Porn and female body shame • Do vulvas / vaginas need washing? • Vaginal discharge • Thrush / candida • The vaginal microbiome • What vaginas are meant to smell like • Recurrent and painful UTIs / peri-meno • D-mannose • Pelvic floor / bladder weakness • Pelvic floor devices and trainers • Sophie’s views on vaginal weight lifting • Vaginal oestrogen and the role of HRT • Pelvic floor training devices • The Emsella Chair • Vaginal atrophy inc. severe pain • PRP for the vagina / the ‘O’ shot • Vaginal rejuvenation and labiaplasties • The language around vaginal procedures • Skincare considerations for the vulva and vagina • How the vulva ages – e.g. labia bigger / vaginas smaller • Vaginal laser devices • Vaginal radio frequency devices • Jade eggs in the vagina – yes or no?

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

Co-host and producer https://fionamattesini.co.uk/

All the other links and notes are here:

Vaginas have their own pH which is somewhere between 3.8 and 4.5 - a healthy vaginal microbiome should be dominated by a good bacteria called lactobacilli, especially the species called lactobacillus crispatus. If you notice a foul-smelling odour, that could be a sign of an overgrowth of one of our vaginal bacteria called gardnerella.

Dr Sophie mentioned Dr. Amy Myers, a functional medicine doctor in the USA - plus Dr Jen Gunter and Dr Kelly Casperson (Dr Gunter says she uses a gentle Cerave cleanser as a vulval wash).

Find out more about The Eve Appeal’s Know Your Body education programme here https://eveappeal.org.uk/news-awareness/know-your-body-education-programme/

Dr Sophie mentioned caprylic acid (found in coconut oil) and a supplement called Candifense which contains enzymes that break down the parasitic and fungal cell walls.

Some people say that a yeast called saccharomyces boulardii really helps candida –a yeast that fights yeast — but while it’s helpful for some, others don’t tolerate it well.

Optibac do a specialist women’s probiotic with lactobacillus paracasei, Lactobacillus rhamnosus, and Lactobacillus reuteri - which are all good bacteria for the vagina.

Fi mentioned Symprove, the liquid supplement.

Dr Sophie mentioned Dr Rachel Rubin who’s a urologist in the US and is doing a lot of campaigning on women’s behalves – e.g. re-naming peri-menopausal UTIs as Genitourinary Syndrome of Menopause (GSM).

Vaginal oestrogen plumps the tissue back up, feeds the vaginal microbiome and according to one study, reduces UTIs by 50%. Read more here: https://www.contemporaryobgyn.net/view/vaginal-estrogen-effective-against-recurrent-utis

Dr Sophie mentioned Professor Chris Harding, a consultant urologist at Newcastle upon Tyne Hospitals NHS Foundation.

Dr Sophie mentioned an NHS-approved hormone based treatment called Prasterone which contains DHEA.

Dr Sophie mentioned an article by the novelist Nina Stibbe which is here https://www.theguardian.com/society/2023/nov/04/nina-stibbe-on-menopause-and-hrt-i-was-glad-to-note-that-my-friend-was-much-worse-than-me-weeing-herself-wise

Dr Sophie mentioned pelvic floor trainers – the Kegel8 is one of the best known.

Dr Sophie talked about the Elvie app and the NHS Squeezy app.

Dr Sophie talked about the Emsella Chair which she offers at her Kent clinic https://illuminateskinclinic.co.uk/condition/urinary-incontinence

Dr Sophie mentioned various women’s health physios including Clare Bourne, Maria Elliott, Kate Walsh, and Caitlin O’Malley.

Diastasis Recti is where the abdominal (tummy) muscles have separated.

The private vaginal atrophy support group is here https://www.facebook.com/groups/1505719029448248/?locale=en_GB

Dr Kelly Casperson has a great podcast on all things gynae.

Intrarosa contains three different types of hormones (inc. testosterone)

Dr Sophie mentioned the YES range of moisturisers – inc. the vaginal Ph gel which can be used internally with a lube applicator.

Dr Sophie mentioned Cheryl Iglesia, a professor of obstetrics, gynecology, and urology at Georgetown University School of Medicine - a leading researcher on energy-based devices.

She says that some preliminary small studies have found slight improvements in vaginal dryness and tightness 6 or 12 months after three treatments of laser or radio frequency. In one study she reviewed, it was found that erbium-YAG lasers may improve dryness slightly more than topical oestrogen – this is promising but she also said that women would need follow-ups over the course of many years to determine how effective and safe the treatments are, especially as women age. Some manufacturers are starting to conduct clinical trials and there have been a few promising, slightly larger placebo-controlled studies – one focused on investigating the link between a radio-frequency therapy called Viveve-1 and sexual satisfaction and found it might improve the collagen, fibroblasts, and connective tissue of the clitoris after menopause, which could lead to enhanced sensation and arousal.

This suggests lasers could be a better option for vaginal dryness while radio frequency might be better for urinary incontinence along with “sexual functioning” – so tightening of the vaginal muscles.

There’s also now Morpheus8 V – this is showing signs of helping with vaginal dryness, weak pelvic floor muscles, incontinence, vaginal wall laxity, recurrent vaginal infections such as candida - and something called lichen sclerosis which is a chronic, inflammatory skin condition more common in women who’ve been through menopause, but it can impact any gender or age. It’s been FDA cleared but at the moment we have no long term data.

Dr Sophie mentioned the Issviva Joylux at-home device – this uses light technology to rebuild collagen and elastin to rejuvenate the vaginal tissues.

Mentioned in this episode:

“From sex drive to fertility – this is a men's health pandemic." – Dr Tracy Gapin guest ep

Tue, 27 Aug 2024 04:05:00 +0000

The men's hormones episode

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

Dr. Tracy Gapin is a trained doctor, Board-certified urologist, and founder of the Gapin Institute in Florida, USA.

He brings over 20 years’ experience focused on men’s health – from sexual performance to stem cell therapy - but has a particular specialism in men’s hormones and hormone optimisation.

His work has been featured in all kinds of places from NBC to TED.

He’s also the author of two best-selling books Male 2.0 and Codes of Longevity.

Head to https://gapininstitute.com/ to find out more and to view his TED talk The Men’s Health Crisis. You can also get a free one pager.

Head to https://drtracygapin.com/ and follow https://www.instagram.com/drtracygapin/

Bookings with Dr Tracy are available online or in-person.

Co-host and producer https://fionamattesini.co.uk/

Mentioned in this episode:

“We now have hard evidence that THIS will slow cellular ageing" - Dr Nichola Conlon guest ep

Tue, 20 Aug 2024 04:05:00 +0000

The cellular ageing episode

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

Dr. Nichola Conlon is a molecular biologist, a leading expert on cellular ageing, and founder of Nuchido NAD+ a unique supplement technology that’s now taking the world by storm – scroll the link to find out more https://info.nuchido.com/dr-nichola-conlon

Dr Nichola is also a highly awarded female founder in the tech space https://www.uktech.news/news/2021s-coolest-uk-female-founders-20210305

Read more about the clinical studies and hard evidence that Dr Nichola mentions on the podcast https://nuchido.com/pages/clinical-evidence

You can find out more by heading to https://nuchido.com/

Follow Dr Nichola on Insta https://www.instagram.com/drnicholaconlon/?hl=en

You can also follow Nuchido here https://www.instagram.com/nuchido/

Dr Nichola mentions Glycanage and Thriva as part of her own healthcare management routine.

Co-host and producer https://fionamattesini.co.uk/

Mentioned in this episode:

"Yes, I take sides in couples therapy. Here's why..." - Terry Real guest ep

Tue, 13 Aug 2024 04:02:00 +0000

The relationship episode

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

Co-host https://fionamattesini.co.uk/

Terry Real is a family therapist who specialises in couples therapy.

He’s considered a leading, innovative voice when it comes to approaching intimacy and relationships.

You can find out more by heading to https://terryreal.com/

Terry is also a best-selling author, and founder of https://relationallife.com/ - this not only trains other therapists but offers workshops for couples, individuals, and parents who want to develop deeper, better relationships.

His books include:

Us: Getting Past You and Me to Build a More Loving Relationship

The New Rules of Marriage: What You Need to Know to Make Love Work

How Can I Get Through to You? Reconnecting Men and Women

I Don’t Want to Talk About It: Overcoming the Secret Legacy of Male Depression

Follow Terry on Insta https://www.instagram.com/realterryreal/?hl=en

Mentioned in this episode:

“Loss of nitric oxide is directly linked to almost every chronic disease” – Dr Nathan Bryan guest ep

Tue, 06 Aug 2024 04:05:00 +0000

The nitric oxide episode

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

Co-host https://fionamattesini.co.uk/

Dr Nathan Bryan trained as a biochemist and physiologist and works as a professor in Molecular and Human Genetics. He’s published over 100 peer-reviewed scientific papers and both written and edited five highly acclaimed books. But he’s perhaps best known as a global pioneer in something called nitric oxide, a critically important gas produced in the body and one considered so essential to our health that in 1998 three scientists won a Nobel Prize for its discovery and Dr Nathan had the unique opportunity to work directly alongside one of those scientists.

To find out more about Dr. Nathan Bryan and his work, you can head to his website: https://drnathansbryan.com/

You can follow him on Instagram https://www.instagram.com/drnathansbryan/?hl=en

…and on Twitter / X: https://x.com/drnitric?lang=en

Plus he has an active YouTube channel https://www.youtube.com/@DrNathanSBryanNitricOxide

Dr Nathan’s supplements and skincare range can be bought via https://n1o1.com/shop/?v=3e8d115eb4b3

For the latest product news, please also follow https://www.instagram.com/n1o1.by.pneuma.nitric.oxide/

Mentioned in this episode:

“Psychedelic drugs are creating profound change for trauma and addiction” – Tracey Tee guest ep

Tue, 30 Jul 2024 04:02:00 +0000

The microdosing episode

IMPORTANT NOTES: This podcast is for information and / or entertainment purposes only.

Dr Sophie is not advocating the use of any illegal substances.

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Co-host https://fionamattesini.co.uk/

Tracey Tee is the founder of Moms on Mushrooms an online community that offers advice, community, and guided micro-dosing courses.

To find out more, head to https://www.momsonmushrooms.com/

Follow Moms on Mushrooms on Instagram https://www.instagram.com/momsonmushroomsofficial/?hl=en

We mention “A Really Good Day: How Microdosing Made a Mega Difference in My Mood, My Marriage, and My Life” by Ayelet Waldman.

You can read about one of the NHS / King’s College London trials here (there are others, ongoing): https://slam.nhs.uk/pressreleases/new-multicentre-clinical-trial-to-investigate-psilocybin-therapy-in-anorexia-nervosa-2659

We mention Dr Himmerich, Consultant Psychiatrist at the South London and Maudsley NHS Foundation Trust and co-lead of the trial.

We also mention Grace Blest-Hopely, a neuroscientist and psychedelic researcher affiliated with King’s College.

Magic mushrooms are a naturally occurring psychedelic plant that contains psilocybin. Taken in large doses, psychedelics will cause a person to hallucinate - seeing or hearing things that don’t exist or are distorted. In smaller doses, which we mostly talk about here, they tend to work in a different way.

In the UK and most other parts of the world, psilocybin (along with LSD) is classified as a Schedule 1 drug – i.e. it’s illegal, and officially defined as having 'no therapeutic benefit'. Advocacy groups are pushing for change in the UK but (at the time of writing) it appears the government has no immediate plans to review or change the status.

In some countries, on the basis research, positive clinical outcomes, and shifts in cultural attitudes, psilocybin has been decrimimalised. In the US, Colorado and Oregon have decriminalised the use of magic mushrooms. Tracey lives in Colorado.

Mentioned in this episode:

"Do not bring your phone into the bedroom!" - Boniface guest ep

Tue, 23 Jul 2024 04:10:00 +0000

The stress and trauma episode

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

Co-host https://fionamattesini.co.uk/

Boniface is one of the world’s most talked-about and in-demand osteopaths, frequently described as a trailblazer and someone reshaping the connection between mind and body – in particular because of his powerful work on what he refers to as body psychology (including a pioneering approach to stress, trauma, and the vagus nerve).

You can find out more or make a booking via https://www.bonifaceosteopath.com/

Please do also follow him on Instagram https://www.instagram.com/boniface_vc/?hl=en-gb

This is Arizona’s foundation: https://www.dirt.charity/

We also mention ‘The Hidden Life of Trees’ by Peter Wohlleben.

Mentioned in this episode:

"This is how to train your brain - and improve your memory" - Prof Mark D'Esposito guest ep

Tue, 16 Jul 2024 04:05:00 +0000

The brain health episode

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en …and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

Co-host https://fionamattesini.co.uk/

Professor Mark D'Esposito is a highly acclaimed neurologist and distinguished professor of neuroscience and psychology at the University of California, Berkeley.

You can find out more by looking at his lab here: https://sites.google.com/berkeley.edu/desposito-lab

Professor Mark mentions, among other things:

The work of https://ianrobertson.org/

Brain HQ https://www.brainhq.com/

The Brain Health Project - find out more via https://centerforbrainhealth.org/

Read more about this in the USA https://www.alzheimers.gov/clinical-trials/brainhealth-project

Professor Mark also talks about Goal Management Training https://gmt.learnworlds.com/

A bit more information on goal management training is here:

https://www.sciencedirect.com/topics/psychology/goal-management-training

This may be of interest to UK listeners:

https://www.kcl.ac.uk/events/launch-of-centre-for-brain-health

Mentioned in this episode:

"I shot up to 1 million - then 2 million followers" - Danae Mercer on going viral guest ep

Tue, 09 Jul 2024 04:02:00 +0000

The self esteem episode

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en …and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

Co-host https://fionamattesini.co.uk/

Find Danae Mercer on her socials @danaemercer as well as on her website https://danaemercer.com/

Danae on Insta quick link > https://www.instagram.com/danaemercer/

We mention that it was only in 2023 that researchers tested period products using blood as opposed to water.

We namecheck another influencer Alex Light – find her on socials @alexlight_ldn

The book Danae mentions is “Eve: How The Female Body Drove 200 Million Years of Human Evolution” by Cat Bohannon.

Dr Sophie mentions a mediation by Dr Joe Dispenza.

Danae mentions a podcast - we checked and it's this one: https://open.spotify.com/episode/36v2KWpyUBK1MYkv3YqjF6?si=llXrEXYFS7WhkkkFz73qkA&nd=1&dlsi=1997fc5a09724b77

Danae mentions she takes prenatal vitamins; ashwagandha; and a @womensbest super green smoothie powder and a @womensbest collagen supplement.

Support for eating disorders is here: https://www.beateatingdisorders.org.uk/ - follow on socials @beatedsupport

Support for body dysmorphia is here: https://bddfoundation.org/ - follow on socials @bddfoundation

"This is why our poop matters" - ZOE's Dr Will Bulsiewicz guest ep

Tue, 02 Jul 2024 04:05:00 +0000

The gut health episode - Dr Sophie Shotter x Dr Will Bulsiewicz

Live the ZOE way with Dr. Will Bulsiewicz – find out more here >> https://zoe.com/willb

Follow Will on socials >> @theguthealthMD

Find out more about 38tera here >> https://38tera.com/

Dr. Will Bulsiewicz – aka Dr B - is a doctor, a gastroenterologist, a researcher, and US Medical Director at https://zoe.com/ He's won multiple awards and contributed to over 20 published articles. He qualified as a medic at Georgetown; got his Masters from Northwestern; and trained in nutrition at Cornell. He's also a New York Times best-selling author. His books include Fiber Fuelled and the Fiber Fuelled Cookbook.

For more, head to https://theplantfedgut.com/

Find out more about Dr Sophie by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Co-host https://fionamattesini.co.uk/

Mentioned in this episode:

At-home biohacking that actually works

Tue, 25 Jun 2024 04:05:00 +0000

Dr Sophie Shotter

Dr. Sophie and Fiona discuss:

• The Sensate • Vagus nerve toning • New research on the vagus nerve • The parasympathetic system • The Eight Sleep mattress • Data around sleep • Dr Matthew Walker • The Oura ring • The Whoop tracker • Sauna blankets • Portable ice baths • Budget options • Weighted blankets • Acupressure mats • Cuddle parties

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Dr Sophie and Fiona mention a few devices, people, ideas and studies – all the links are here (press ‘episode website’ for the full list):

The Sensate The Eight Sleep mattress The Oura ring Whoop Apollo Myzone Aeyla weighed blankets

vBloc have FDA approval for a pacemaker-like device that can be implanted in patients with high body mass index.

Another company have created a wire you could wrap around the vagus nerve in the neck, potentially helping to reduce the frequency of seizures in people with epilepsy.

There’s also an earbud device that stimulates a part of the vagus nerve that branches out into the middle of the ear to help reduce anxiety.

There are even some schools of thoughts that vagus nerve stimulation – or vagal toning - might improve brain health.

There’s emerging data that if you pair vagal nerve stimulation with certain behaviours, you can improve “plasticity.” For example, one study has been pairing vagal stimulation through the ear with teaching babies how to breastfeed. It could also potentially help stroke patients who are trying to gain mobility in parts of their bodies – or even someone trying to learn a new skill such as learn a new language.

There’s emerging science from Dr Joe Dispenza on the health benefits of mediation.

Dr Sophie mentions Dr Matthew Walker and ‘Why we sleep’ inc. the data he’s amassed – for example:

After one week of short sleep, blood sugar levels are disrupted so significantly that your GP would classify you as pre-diabetic. Men who are limited to just four or five hours of sleep a night in just one week will have a level of testosterone usually seen in someone 10 years older. Lack of sleep can increase risk of diabetes, obesity and dementia. A lack of sleep will cause you to eat more during the day. Because when you’re tired your body produces more of a hormone call ghrelin, which tells you you’re hungry. That can lead to people who are not getting sufficient sleep eating somewhere between an extra 280 to 400 calories every single day.

The show briefly mentions Sleepme’s Chilipad Dock Pro; BedJet 3; and Sleep Number Climate360.

The Oura can be paired with the Natural Cycles app.

The show mentions Aeyla’s weighted blankets and acupressure mats from Bed of Nails.

More on cuddle parties here: https://en.wikipedia.org/wiki/Cuddle_party

Microneedling for beginners

Tue, 18 Jun 2024 04:05:00 +0000

Dr. Sophie Shotter

Dr Sophie and Fiona discuss:

• What is microneedling and how does it work? • Derma roller versus Skin Pen • What Victoria Beckham posted on socials • What can microneedling treat? • Does it hurt? • What’s the downtime like? • Do’s and Don’t’s post treatment • How soon can results be seen? • How to amplify the results with serums / PRP • Can you microneedle your body? • Microneedling and scarring / stretch marks • How often should we get it done? • Combining with other treatments • Who shouldn’t microneedle? • Dr Sophie’s thoughts on at home micro needling devices

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Dr Sophie mentioned the Skin Pen’s FDA clearance as a de Novo technology.

She also mentioned combining microneedling with Profound RF or Morpheus 8.

Mentioned in this episode:

Necks, knees, hands, jowls (+ other tricky areas)

Tue, 11 Jun 2024 04:00:00 +0000

Dr. Sophie Shotter

Dr. Sophie and Fiona discuss:

• Crepey skin on the knees • Profhilo Body • New techniques with bio-stimulators • What surgery entails • Thread lift procedures • Wrinkle relaxers • A holistic approach • Excess fat on the knees • AirSculpt • The Emerald Laser • Fat dissolving injections • Nail staining (+ DIY hacks) • Hand creams • Prominent veins on the hands • Filler on the hands • HArmonyCa in the hands • Specialist surgery • Chemical peel techniques + laser treatments • Excess fat on the arms • Profhilo • RF microneedling • CoolSculpting • An arm lift/brachioplasty • Lines and wrinkles on the decolletage • Injectables • Energy-based tech • Microneedling • Necks and non-surgical solutions • Skincare for the neck and decolletage • Jowls (and the options available) • Volux • Options for a double chin

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Dr Sophie and Fiona mention a few studies – all the links are here (press ‘episode website’ for the full list):

The various treatments and tweakments Dr. Sophie mentioned include:

Profound RF microneedling

SkinPen microneedling

BELKYRA fat dissolving (Kybella in the US)

CoolSculpting (plus the CoolMini and Cool Petite)

The Emerald laser

The liposuction procedure Dr. Sophie mentioned is called Air Sculpt - developed by Dr. Aaron Rollins.

HarmonyCa

Profhilo

Juvelook

Sofwave

PhilArt (skin booster)

VOLUX from Juvederm

Dr Sophie recommended:

BodiFirm by Revision Skincare

Sally Hanson’s Tinted Colour Correcting Nail treatment

Creative Nail Design’s Rescue Daily Keratin Treatment

Meder beauty ‘s Salva Hand Cream and their Circa Hand Cream

Otto’s CBD hand balm

La Roche Posay’s Cicaplast hand cream

Revision Skincare’s Nectifirm Advance

Skin Better Science’s Techno Neck Perfecting cream

Alastin’s Restorative Neck Compex

Absolute Collagen’s Deep Lift Neck and Dec cream

Fiona mentioned the Nora Ephron book, “I Feel Bad About My Neck: And Other Thoughts on Being a Woman”

Mentioned in this episode:

A crib sheet on fillers

Tue, 04 Jun 2024 04:00:00 +0000

Dr. Sophie Shotter

Dr Sophie and Fiona discuss:

• What are fillers? • The different types of filler (inc. hybrid injectables) • What results can be achieved with fillers? • So much choice – is it different brands or different products? • Fillers and skin boosters – what’s the difference? • HArmonyCA v Radiesse • Which is better for lines – fillers or wrinkle relaxers? • What’s the experience like (and does it hurt)? • Do’s and Don’ts before treatment • How soon to see results – and what’s the downtime like? • Risks and side effects • Post treatment protocols • Lip filler / baby lip filler / staying natural • Results – and how long it lasts • Where does filler go once it’s worn off? • The Alice Hart-Davies report on extended longevity • Getting filler dissolved • Post-Hyaluronidase Syndrome • How to stay looking natural • Regulations and safety in the UK • Is there anyone who can’t have fillers? • Final thoughts and tips

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Dr Sophie mentions a few brands plus a study and an article – all the links are here (press ‘episode website’ for the full list):

These are some of the key brands Dr Sophie uses in clinic (some are fillers – some are skin boosters or hybrid products):

HArmonyCa

VOLBELLA, VOLUMA, VOLUX, VOLIFT (in the USA: Vollure) and VOLITE (in the USA: SKINVIVE) – all from Juvéderm

JUVELOOK & LENISNA

Profhilo

Viscoderm Hydrobooster

Dr Sophie also mentioned using fillers in conjunction with Profound RF or Sofwave.

Dr Sophie also mentions these brands:

Restylane Teoxane Sculptra Ellansé Radiesse MaiLi IBSADERMA Aliaxin

Dr Sophie mentions these products:

Alastin’s Immerse serum SkinCeuticals HA Intensifier Serum The Youthful Lip Replenisher from Revision Skincare

The study Dr Sophie mentioned is here: https://pubmed.ncbi.nlm.nih.gov/38655103/

More on the Alice Hart-Davies report Dr Sophie mentioned can be found here: https://thetweakmentsguide.com/blog/how-much-filler-did-alices-mri-reveal/

In the UK, there are resources including:

https://www.jccp.org.uk/ and https://www.saveface.co.uk/

Plus you can check the regulatory register to find out if your practitioner is a registered healthcare provider. This includes the General Medical Council, the General Dental Council and the Nursing and Midwifery Council.

Mentioned in this episode:

Teen skin

Tue, 28 May 2024 04:05:00 +0000

Dr. Sophie Shotter

Dr. Sophie and Fiona discuss:

• The issue with young people using actives • The role of sugar (and cortisol) • What happens during puberty • Teenage spots versus acne • A good basic skincare routine • Do pre-teens need skincare? • Dr Sophie’s recommended products and brands • What can a doctor prescribe? • Lymecycline (and other antibiotics) • Azelaic acid and benzoyl peroxide • Adapalene • The pill • Roaccutane – the full lowdown • Final tips

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Dr Sophie mentions a few products and brands:

Heliocare 360 Oil-Free gel

Byoma skincare

Indu skincare

Sam Farmer skincare

Cerave skincare

La Roche-Posay’s Effaclar range

Oxygenetix Acne Control Foundation

Mentioned in this episode:

Taking a holistic approach to cancer - part 2

Tue, 21 May 2024 04:00:00 +0000

Dr. Sophie Shotter

Dr Sophie and Fiona discuss:

• Spontaneous tumour regressions • The role of the immune system • The work of Dr. Joe Dispenza • Off licence meds • Early cancer detection tests • Gut health in relation to cancer • Autophagy and theories on cancer as a metabolic disease • The role of glucose • Dental health • Environmental chemicals / heavy metals • Obesity - insulin resistance - inflammation • The role of alcohol / exercise / diet

The podcast is for entertainment / information purposes only. Always seek medical advice from a registered doctor.

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Dr Sophie and Fiona mention a few studies – all the links are here (press ‘episode website’ for the full list):

This ep mentions the stories of:

Ole Nielsen Schou, a Danish pharmaceutical production manager (when his abdominal cancer tumour was removed, they found lots of white blood cells, the lead weapon in the body's immune system).

Sharon Belvin from North Carolina.

Joseph Rick from LA.

GlaxoSmithkline is in final-stage tests of a vaccine to prevent lung cancer from coming back after surgery. In an early trial it slashed the probability of cancer recurrence by 27%.

More recently, there was a peer reviewed publication showing that meditation can block the COVID virus from entering cells. It examined how blood plasma can limit viral infection in cultured lung cells.

Another interesting discovery is that meditation can elevate a protein called SERPINA5.

Fiona mentioned the work of Jane McClelland and her book ‘How to starve cancer’ - Jane has an active Facebook group.

Meds discussed include herceptin, ivermectin, resveratrol, merformin, herceptin, LDN, and melatonin. Never take meds without a doctor's advice.

Erbitux discussed re colon cancer – designed to disrupt the growth of cancer. Might perform a second role which is flagging the immune system to actually kill cancer.

Ivermectin - used to treat parasitic infections. It’s been linked to treatment for various cancers as well as COVID 19 – but we have no firm data (there’s also concern about whether it causes infertility in men).

Resveratrol (found in grape skins) has anti-inflammatory, antioxidant and cardio-protective effects – potentially has anti-cancer properties by activating or deactivating molecular pathways. But no hard data - much more research is needed.

Metformin, this is a medication that helps the insulin you produce work better. It's for people with type 2 diabetes or gestational diabetes. A series of epidemiological studies have suggested that metformin may prevent cancer – on the Cancer Research UK site, it mentions a study on metformin and breast cancer. We don’t have the results yet.

Interesting article here https://sperlingprostatecenter.com/biohacking-with-metformin/

Re MSM (methylsulfonylmethane). Some research suggests MSM may help slow the spread of certain cancers and even promote cancer cell death. One study showed MSM inhibited (HER2) in breast cancer cells. Another study suggests MSM may improve the way chemotherapy drugs affect cancer cells and may itself induce endometrial cancer cell death. But no firm data.

MSM supplements might also decrease the appearance of wrinkles and improve skin firmness and elasticity. This was a small 2022 study in the International Journal for Vitamin and Nutrition Research. We think this is due to its antioxidant and anti-inflammatory effects.

There are also products called PC-HOPE, PC-CARE and PC-PLUS - all very similar products and research on PC-HOPE and PC-SPES showed they might be active against prostate cancer cells and PC-HOPE might kill pancreatic cancer cells or help people with pancreatic cancer to live longer. But no firm data.

True Check Intelli mentioned - available at Dr Sophie's Kent clinic.

Alzheimers and Dr Dale Bredesen’s work mentioned.

There is data that probiotics (in particular a strain called Escherichia coli) could amplify cancer immunotherapies such as CAR T therapy – which is a treatment for certain blood cancers. There’s an interesting study on this published in Science – here: https://www.science.org/doi/10.1126/science.add7034? BUT this study has been on mice and it’s not yet known how this experimental combination might work in humans.

There’s emerging data on fructose receptors in cancer tissue.

Dr Mindy Peltz mentioned.

Autophagy has been associated with cancer because studies show that fasting reduces insulin growth factor (IGF-1) levels, a marker for increased cancer risk - but there’s no clear-cut data. For instance, some studies have shown that autophagy may prevent tumours from forming in the early stages of cancer. As just one example, pre-clinical findings from a pancreas research team in the US indicates that fasting could play a role in preventing liver and prostate cancer. But other research has shown that autophagy may encourage tumor growth by helping cancer cells function more efficiently. Also, most studies about the relationship between autophagy and disease haven’t been performed on humans.

It is true that autophagy is essential for healthy cells. It’s also true that problems with autophagy are associated with some diseases. But there’s not enough research to support inducing autophagy as a wellness strategy.

Studies involving animals suggest that autophagy begins somewhere between 24 to 48 hours of fasting. Some researchers believe it takes longer but we don’t have enough research on the ideal timing to trigger human autophagy.

One study concluded that intermittent fasting consistently showed powerful anti-cancer effects when used in combination with conventional treatments. The fasting appeared to amplify the effects of chemo, radiotherapy and TKI cancer therapy. But as a standalone approach, this study says that fasting would probably show limited efficacy against established tumours. In fact, the researchers said it rarely matched the benefits they saw in this combined approach. That said, some people have used fasting as a stand-alone therapy with powerful results – including spontaneous remission from cancer.

Here’s one study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6938162/

Maggie Jones story is here https://drmindypelz.com/ep184/

Dr Mark Hyman mentioned.

Dr. Thomas Seyfried – his work is on the metabolic theory of cancer plus the role of oxidative stress, mitochondrial health, and the role of glucose in the development and progression of cancer. His theory says cancer cells need glucose and glutamine to fuel their growth and therefore why we need to deprive cancer cells of glucose. He endorses using a ketogenic diet - whereas someone like Dr Mindy Peltz endorses using intermittent fasting (which has the benefit of not needing to cut any food groups). They both get to the same end result but using different approaches.

Chemicals discussed including pesticides, phthalates, bisphenol A, flame retardants, and heavy metals such as mercury, lead, and arsenic.

Exposure to asbestos increases risk of lung cancer.

Dr Sophie mentions the benefits of a plant-based diet especially foods with sulforaphane. This is a chemical that’s made when chewing cruciferous vegetables such as broccoli, cauliflower, and broccoli sprouts. A chemical in these vegetables called glucoraphanin mixes with an enzyme in humans called myrosinase, which produces sulforaphane.

Alcohol is linked to certain cancers, particularly breast cancer. Even small amounts.

Many people also believe that daily exercise, both cardio and resistance training, is imperative for cancer prevention. There’s emerging data here.

The role of sleep and reducing stress levels is interesting – data emerging too.

Dr. Patrick Soon-Shiong is creating targeted therapies to treat cancer in every patient individually.

Some scientists are making strides in cancer treatment by focusing on metabolic pathways – in particular with work on the enzyme SHMT with aggressive cancers.

Dr. Dean Ornish endorses a whole-foods, plant-based diet.

Mentioned in this episode:

Taking a holistic approach to cancer - part 1

Tue, 14 May 2024 04:00:00 +0000

Dr. Sophie Shotter

Dr Sophie and Fiona discuss:

• Taking vitamins / supplements while in treatment • Chinese herbs and UK oncology • Dr Sophie’s blood tests in clinic • Do B vitamins play a protective role? • Vitamin C • Vitamin D • Bromelain • Essiac • Laetrile • Dame Deborah James • Turmeric • Ginger • Selenium • Garlic • Green tea • Vitamin E • Iodine • The immune system • Functional mushrooms / adaptogens • Soy (and the breast cancer discussion) • NAD+ • Glutamine

The podcast is for entertainment / information purposes only.

Always seek medical advice from a registered doctor.

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Dr Sophie and Fiona mention a few studies – all the links are here (press ‘episode website’ for the full list):

In December 2019, a study of over 1,000 women with breast cancer found that certain nutritional supplements could reduce women’s chance of survival and even increase the chance that breast cancer would recur after treatment. The research was published in the Journal of Clinical Oncology and led by scientists at the SWOG cancer research institute.

The main findings were:

• Patients who reported taking any antioxidant - vitamins A, C, E plus carotenoids and Coenyzme Q10 - were 41% more likely to have their breast cancer return when they took the supplements both before and during chemotherapy treatment.

• Patients had a similar, but weaker, increased risk of death when taking those antioxidants.

• Patients taking vitamin B12, iron, and omega-3 fatty acid supplements were at significantly greater risk of breast cancer recurrence and loss of life.

• Patients taking multivitamins showed no signs of poorer or better outcomes after chemotherapy.

• But it found no evidence that taking multivitamins or vitamin D is harmful.

Half a million people were behind Johns Hopkins research which concluded that multivitamins did not decrease the risk of cancer, heart disease or help with any cognitive decline. But there are other studies that state the exact opposite – more research and data is needed.

Dr Bav Shergill of the British Association of Dermatologists has suggested oral niacinamide (vitamin B3) might reduce the rates of some types of non-melanoma skin cancer (as well as reduce skin redness and uneven pigmentation). Read more here: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9125143/

In one study, fish oil was shown to possibly reduce the effectiveness of chemotherapy. https://jamanetwork.com/journals/jamaoncology/article-abstract/2212208

According to some research folate and other B vitamins like B12 might offset increased risk of cancer in people who drink alcohol. Again, more research is needed.

Cancer Research UK cites two studies suggesting vitamin C’s potential as a cancer treatment. However, the researchers were injecting [either mice or cancer patients] with very high doses of vitamin C – much higher than you could get from food or supplements directly. The results tentatively support the idea that high-dose vitamin C has potential as a cancer treatment. But it’s far from clear-cut because other studies suggest vitamin C could interfere with some anti-cancer drugs, with one study showing it may even stop the anti-breast cancer drug tamoxifen. So far, we don’t have enough quality research. One study is here: https://jeccr.biomedcentral.com/articles/10.1186/s13046-021-02134-y

Research continues to look at the role of vitamin D in the development and recurrence of different cancers. Some early studies suggest that there is a link between low levels of vitamin D and the development of cancer.

One study found that vitamin K2 was effective at inhibiting the pro-inflammatory iNOS in the spinal cord and the brain immune system (this was in rats that had multiple sclerosis symptoms). Read more here: https://www.ncbi.nlm.nih.gov/pubmed/16146654

Note: MK-4 is thought to play a role in cancer protection and sexual health.

Laboratory and animal studies have showed that bromelain might reduce inflammation for certain skin conditions and even osteoporosis. Some studies show that bromelain might prevent or treat certain cancers and that it might stop them from growing. Very limited data available.

Several studies and reviews found that Essiac had no anti cancer effects. Likewise there’s no reliable scientific evidence to show that laetrile or amygdalin can help treat cancer.

The main active ingredient in turmeric is curcumin or diferuloyl methane. Laboratory studies have shown curcumin seems to be able to kill cancer cells and prevent more from growing. There have been some clinical trials looking at curcumin in people with colorectal cancer, prostate cancer and other cancer types. It’s best to take it with black pepper to increase absorption.

In 2006, researchers from the University of Michigan Comprehensive Cancer found that ginger not only killed ovarian cancer cells, it also prevented them from building up resistance to cancer treatment. More research is needed.

Too much selenium can be toxic, but doses as high as 300 micrograms (mcg) have been shown to reduce certain kinds of cancer, including lung, liver and colon. Read more here: https://www.pcrm.org/health/cancer-resources/diet-cancer/nutrition/how-selenium-helps-protect-against-cancer

One trial showed that selenium might protect against the overall risk of prostate cancer in men with a history of non melanoma skin cancer. However a later systematic review found that selenium supplements had no benefit. In fact, some randomised controlled trials showed a higher incidence of high grade prostate cancer and type 2 diabetes in people taking selenium. So research in this area has produced very mixed results.

There are some studies that suggest garlic has properties that block the activation of cancer-causing substances and reduce the growth of cancer cells.

There are several studies that show the compounds in green tea could help protect against certain kinds of cancer. It contains chemicals called polyphenols that have antioxidant and anti-inflammatory properties. But green tea does have antioxidant properties so you do really need to check with your oncology team. Read more here: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3142888/

Studies show vitamin E can decrease the risk of prostate, colon, and lung cancers. In fact, low amounts of vitamin E is shown to increase the risk of cancer. Again, be careful with taking antioxidants while in active cancer treatment. Read more here: https://www.pcrm.org/health/cancer-resources/diet-cancer/nutrition/how-vitamin-e-helps-protect-against-cancer

There are theories around other supplements such as iodine.

Adaptogenic mushrooms and herbs have been shown to have a balancing effect on the hypothalamic-pituitary-endocrine axis. This controls hundreds of pathways that are responsible for inflammation. And because chronic inflammation is linked to cancer (along with many other health issues), adaptogenic mushrooms have potential (though as yet unproven) benefit. Read more here: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396833/

There are several studies that show impressive results with cancer patients – including shiitake, himematsutake - also known as God’s mushroom, chaga, maitake, and turkey tail (which also has data to help SIBO and candida / yeast overgrowth).

Current research says that foods containing natural isoflavones are safe. Early studies show that isoflavones may have some benefits in certain cancers. In breast and prostate cancer isoflavones may actually reduce the risk of cancer coming back. This is because isoflavones are similar to the hormone oestrogen and bind to the oestrogen receptors on cells. By doing so, it blocks cancer cells from absorbing oestrogen.

While there is no research to show NAD+ can cause cancer, studies show if you cut off the NAD+ supply cancer cells die. The same applies to glucose and oxygen - but this does not mean glucose, oxygen or NAD+ cause cancer, nor is it a sensible approach to restrict any of these critical molecules.

There appears to be a link between glutamine and cancer. On the flip side, glutamine supplementation may improve the overall outcome of certain cancer cases. In fact, glutamine is believed to be such an important part of tumour progression that some researchers have studied it as a potential cancer treatment. It has great potential for immune-enhancing effects which may, in part, be because glutamine acts as primary fuel in lymphocytes, a type of white blood cell that helps your body’s immune system fight viruses and bacteria. And doctor-supervised glutamine supplementation may be of value in healing of tissues affected by chemotherapy or radiotherapy. It’s also been shown to have potential cognitive benefits. Plus some research indicates that higher blood glutamine levels may actually be protective against cardiovascular disease. But it’s complicated because (like NAD+) both healthy cells and cancerous cells need glutamine. NB. The body makes its own glutamine so dietary changes are likely to have little effect. It’s also found in a range of foods. Much more research is needed. Read more below.

https://www.healthline.com/health/glutamine-and-cancer

https://pubmed.ncbi.nlm.nih.gov/8257221/

Mentioned in this episode:

The pregnancy and breastfeeding episode

Tue, 07 May 2024 04:00:00 +0000

Dr. Sophie Shotter

Dr. Sophie and Fiona discuss:

• The reasons women need to re-think their usual routine when pregnant • Can pregnant / breast feeding women have wrinkle relaxing injections? • Can pregnant / breast feeding women have fillers and skin boosters? • Skincare alternatives • Dissolving filler while pregnant • Can pregnant / breast feeding women have lasers / IPL / microneedling? • Using topical numbing agents like lidocaine • Can pregnant / breast feeding women have a chemical peel? • Salicylic acid while pregnant • Safe chemical acids while pregnant • Topical vitamin C • Other things to avoid while pregnant • Prescription drugs used for acne - spironolactone / Roaccutane • Parabens • Physical positioning during a facial • Melasma • Crepey tummies post pregnancy / stretch marks / pelvic floor • Diastasis Recti • Skin changes during pregnancy • Spider Nevus • Self-care after pregnancy / managing expectations

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Dr Sophie and Fiona mention a few studies – all the links are here (press ‘episode website’ for the full list):

Below is a study to reassure women who had botulinum toxin before knowing they were pregnant (but this wasn’t a placebo controlled ‘quality’ study so again, far more evidence needed – and Dr Sophie would never knowingly treat a pregnant woman – nor should anyone else). This is purely to reassure.

https://pubmed.ncbi.nlm.nih.gov/26635276/#:~:text=Conclusions%3A%20A%2024%2Dyear%20retrospective,rates%20in%20the%20general%20population

Various studies show that alpha hydroxy acids can be beneficial in treating hyperpigmentation, and they’re generally safe to use in pregnancy.

Bakuchiol is a retinol alternative that’s safe in pregnancy – it’s a plant-based ingredient and in one study performed just as well as retinol from an anti-aging standpoint. This is a good article that compares both ingredients: https://www.bareluxeskincare.com/blogs/elevated-simplicity/bakuchiol-vs-retinol

Chemical sunscreens that contain oxybenzone, avobenzone, octisalate, octocrylene, homosalate, or octinoxate should be avoided as these will absorb into the bloodstream and there are concerns about hormone disruption.

Look out for phthalates / formaldehyde / toluene in perfume and nail polishes. Research is being carried out to assess a possible link with birth defects.

Also look out for ammonia found in some hair dyes – several studies show this has carcinogenic properties.

Spironolactone has been liked to birth defects so should be avoided.

Research published by the University of Reading in 2012 found parabens and aluminium in women who’d had breast cancer – although no definite causal link has been identified. But some women choose to avoid them during pregnancy. Parabens are often used as preservatives in things like shampoo.

Many essential oils increase the skin’s sensitivity to UV light or have the potential to over-stimulate and encourage menstruation. The ones to avoid are basil, rosemary, juniper berry, jasmine, cypress and chamomile blue plus camphor, peppermint extract, and mint oil.

After 16 weeks, pregnant women should avoid sleeping on their back. And after 28 weeks, data tells us that back sleeping doubles the risk of stillbirth.

Research has found that pregnancy can accelerate cellular ageing. Read more here: https://www.healthline.com/health-news/having-a-baby-can-age-you

Dr. Sophie and Fiona discussed (but didn't recommend) Kim Anami, the so-called vaginal weight lifter.

Dr. Sophie recommends:

Skin Better Science Interfuse lines (contains a filler grade HA to work inside-out).

Meder Beauty Lipo-Oval products - concentrate and face masks.

The Bionic laser.

Meder Beauty facials.

HydraFacial (although Dr. Sophie may avoid using the peel component in some people).

Nailberry - nail varnishes formulated to be "12 chemical free".

Revision Skincare Body Firm cream (for stretch marks).

The Elvie for the pelvic floor.

The Emsella chair for the pelvic floor.

Mentioned in this episode:

So what's the deal with lasers (+ LED / IPL)?

Tue, 30 Apr 2024 04:05:00 +0000

Dr. Sophie Shotter

Dr. Sophie and Fiona discuss:

• What do lasers do best? • An explainer on the different brands • Brand hype versus actual technology • Ablative lasers • Non-ablative lasers / ‘fractional’ technology • Impacts on the skin barrier • What’s the difference between IPL, laser, and LED? • LED’s ability to treat rosacea / psoriasis and other autoimmune disease • What Dr. Sophie uses in-clinic • What’s the experience like? • Results • Treatment protocols • Could people with sensitive skin have a laser treatment? • Maintenance (how many sessions needed)? • Darker skin tones • Post-inflammatory hyperpigmentation (PIH) • Hyped lasers (are they worth the hype?) • At-home laser devices

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Dr. Sophie and Fiona mention a few studies – all the links are here (press ‘episode website’ for the full list):

One study found that red and blue light therapy helped clear plaque psoriasis and there’s hefty anecdotal support for red light helping to reduce the inflammation that leads to rosacea flushes. Read more here: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5756569/

Dr. Sophie uses the Byonik and the Emerald

There are various laser technologies (or types of laser) - a few examples Dr. Sophie mentions are:

The Aviclear Ruby Alexandrite Diode ND:Yag KTP (but this isn’t an exhaustive list).

Dr. Sophie recommends the Dermalux Flex at-home LED device.

The Baby Face refers to a non-ablative treatment from Lutronic.

The Endolift and Lyma were also mentioned in the chat - as was Dr. Priya Verma in London (for the Endolift).

Mentioned in this episode:

16 things you need to know about sunscreen

Tue, 23 Apr 2024 04:05:00 +0000

Dr. Sophie Shotter

Dr. Sophie and Fiona discuss:

• The sunscreen reapplication issue • A reapplication tip • Mineral v chemical sunscreens (and an explainer) • UVA and UVB – what you really need • Is there that much of a difference between Factor 30 and 50? • Can we tan safely? (+ a brand with a different approach) • Does SPF makeup offer enough protection? • What about skincare with a built in SPF? • How effective is water resistant sunscreen? • Do sunscreens block pores? • How to wear makeup and sunscreen • The science behind using antioxidants as sun protection • Astaxanthin (and the TikTok influencer) • Supplementing melatonin • Does being in the sun give health benefits? • What about vitamin D? And S.A.D.? • The PA+ ratings on sunscreens – an explainer • Should we wear sunscreen when flying / driving? • Sunscreens and the issue of coral reefs • Is there anything we can do to reverse sun damage? • Dr. Sophie’s product ‘loves’ and recommendations • Polarised sunglasses • Do any meds mean you need more sun protection? • UV clothing • How to store sunscreen • Dr. Sophie’s MOST IMPORTANT TIP! • And finally…do YOU know this song?

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Dr Sophie and Fiona mention a few brands, ideas, studies and individuals – all the links are here (press ‘episode website’ for the full list):

The stickers that Dr. Sophie mentions are described in this article https://www.allure.com/story/uv-stickers-reapply-sunscreen-tiktok

More on Institut Esthederm’s approach to tanning https://www.sweetcare.com/gb/sweet-mag/institut-esthederm-suncare-i-1568

Here’s the make-up compact Dr. Sophie mentions https://www.skinbetter.com/shop-skincare/product-category/sunscreens/sunbetter-tone-smart-spf-68-sunscreen-compact-M024.html

Here are the powders https://colorescienceuk.com/products/sunforgettable-total-protection-brush-on-shield-spf-50?variant=7076584751169

The Kate Somerville SPF make-up spray seems to be out-of-stock in the UK. There are others – for example this one from E.l.f. [note: Dr. Sophie hasn’t used this one so this is an example only]: https://www.elfcosmetics.co.uk/suntouchable-all-set-for-sun-spf-30/81514EU.html

There are emerging studies on astaxanthin – such as this one: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6073124/

And a study to read on supplementing melatonin is here: https://pubmed.ncbi.nlm.nih.gov/24164339/

Some research has shown a class of antioxidants in certain fruit and bark has a dual protective effect against damage from UVA rays. Read more here: https://www.mdpi.com/2076-3921/11/3/471

These are the capsules Dr. Sophie takes https://heliocare.co.uk/products/oral-supplements

Check if your sunscreen is environmentally sound here: https://savethereef.org/about-reef-save-sunscreen.html

Some of the sunscreen brands mentioned and recommended include:

La Roche-Posay Anthelios

EltaMD UV Clear

Intradermology Synergy 6

Revision Intellishade TruPhysical

The Heliocare range

The Institut Esthederm range

A couple of round up articles here:

https://www.elle.com/uk/beauty/skin/g11759/best-spf-suncreens/

https://www.elle.com/uk/beauty/skin/g32735/best-face-sun-cream-spf-acne-spots-non-comedogenic/ < this one for people with acne

More on polarised sunglasses here https://www.verywellhealth.com/polarized-sunglasses-3422163#:~:text=Polarized%20sunglasses%20are%20designed%20to,%2C%20boating%2C%20or%20playing%20sports.

And finally, here’s that Baz Luhrmann song (enjoy) https://www.youtube.com/watch?v=sTJ7AzBIJoI (and wear sunscreen!)

Mentioned in this episode:

Everything you wanted to know about wrinkle relaxers

Tue, 16 Apr 2024 04:05:00 +0000

Dr. Sophie Shotter

Dr. Sophie and Fiona discuss:

• How wrinkle relaxers (toxins) work • Can wrinkle relaxers be used on all lines and wrinkles? • Can wrinkle relaxers be used on the body? • Do wrinkle relaxers prevent lines from forming / getting worse? • The in-clinic experience • What happens immediately after a treatment • Trends / dosage / the natural look • Protocols and advice • Myth-busting • Can you cleanse your face that night? • Skincare • Does exercise make it wear off more quickly? • Combining wrinkle relaxers with filler • Risks and challenges • Can it cause bags under the eyes / make these worse? • Lymphatic drainage • Safety and efficacy • Different brands (and industry issues) • Is there such a thing as a ‘clean’ toxin? • Finding the right practitioner • What happens if you suddenly stop using them?

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Dr Sophie and Fiona mention a few studies – all the links are here (press ‘episode website’ for the full list):

One study showed that botulinum toxin can boost levels of collagen in the skin (while it’s active in the skin): https://pubmed.ncbi.nlm.nih.gov/22742715/

Alastin’s post-procedure product is here: https://alastin.com/products/inhance-post-injection-serum

A study conducted in 2012 found that toxin’s longevity increased by 30% in patients who took 50mg of zinc daily. Read more here: https://pubmed.ncbi.nlm.nih.gov/22453589/

In the UK, head to BCAM or BACN to find a reputable practitioner.

A 2008 paper published in the Journal Of The European Academy of Dermatology showed that when you remove the wrinkles from a photo, a person is perceived as ten years younger than they really are, but when you remove the wrinkles AND even out the pigmentation, the person is perceived as almost 16 years younger.

Mentioned in this episode:

Cellulite, stretch marks, stubborn fat and loose skin

Tue, 09 Apr 2024 04:05:00 +0000

Dr. Sophie Shotter

Dr. Sophie and Fiona discuss:

• Body positivity and personal choice • What causes cellulite? • The role of diet and exercise • Lotions and potions • Body brushing / lymphatic drainage • Clinic grade treatments and devices • What to do about stretch marks • Pockets of stubborn fat • Loose skin following pregnancy / weight loss • Body positivity influencers • A new technique pioneered by an American surgeon • Cellulite is very common and very normal!

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Dr Sophie and Fiona mention a few studies – all the links are here (press ‘episode website’ for the full list):

Dr. Sophie recommends:

https://www.paulaschoice.co.uk/skin-smoothing-retinol-body-treatment/m5800.html

https://bodyballancer.co.uk/

https://www.flaviamorellato.co.uk/

https://dimple-amani.com/pages/body

She also discusses:

https://www.healthline.com/health/cellfina

Morpheus8 microneedling

Venus Viva radiofrequency skin resurfacing

Profound RF microneedling

Profhilo Body

AirSculpt at Elite Body Sculpture (Dr Aaron Rollins)

Data is still emerging on acoustic wave therapy – here’s one study https://www.beamedtrading.com/wp-content/uploads/storz_aesthetics_pdf/Adatto_AWT__Volume_Reduction.pdf

Meet Chessy King https://www.stylist.co.uk/people/chessie-king-instagram-influencer-body-positivity-love-your-body/274717

…and Danae Mercer https://danaemercer.com/

Mentioned in this episode:

A run-down on rosacea / sensitive skin

Tue, 02 Apr 2024 04:05:00 +0000

Dr. Sophie Shotter

Dr. Sophie and Fiona discuss:

• Is it sensitivity or rosacea? • The symptoms of sensitivity (possible links to other issues) • The different types (and symptoms) of rosacea • The importance of managing symptoms asap • Fiona’s experience and how it cleared up • Perimenopause and the link with acne rosacea • Rosacea triggers • Will HRT help? • What causes rosacea? • A link between rosacea and a stomach bacteria • The role of stress • Rosacea skincare / product recommendations
• Products labelled “hypoallergenic” • What to look for in a skincare range • Can you use acids? • Can you use retinoids? • Thoughts on SPF • Topical antibiotics • Ivermectin • Roaccutane • Low dose (oral) antibiotics • Laser treatment • Facials • Peels • LED light • Prescription creams for flushing • How muscle relaxants can help • Gut health and rosacea • Foods that could be a trigger • Make-up • Is taking skincare samples home…theft?! • Who is most prone to rosacea? • Darker skin types and rosacea

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Dr Sophie and Fiona mention a few brands, ideas, studies and individuals – all the links are here (press ‘episode website’ for the full list):

The cream Fiona was prescribed: https://www.mayoclinic.org/drugs-supplements/ivermectin-topical-application-route/side-effects/drg-20075441?p=1#:~:text=Ivermectin%201%25%20topical%20cream%20is,only%20with%20your%20doctor%27s%20prescription.

Sophie’s On Stella article https://www.onstella.com/the-latest/dryness-itchiness/a-guide-to-rosacea-menopause-treatment/

Research that shows a possible link between rosacea and a bacteria called helicobacter pylori https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042414/

Sophie recommends:

Revision Skincare Gentle Cleansing Lotion

Meder Beauty Net-Apax Prebiotic Cleansing Mask

The Byoma range https://byoma.com/uk/

CeraVe Hydrating Cleanser

La Roche-Posay Toleriane range

Sophie also recommended PHAs - Polyhydroxy acids

NeoStrata’s Restore range

Sophie talked about azelaic acid

Sophie also flagged granactive retinoids

She talked about Elizabeth Arden Retinol + HPR Ceramide cream

Byoma’s Retinol oil with granactive retinoids

Meder Beauty Red Apex Concentrate

SkinCeuticals PhytoCorrective Serum

Synchrorose by SkinMed

La Roche-Posay’s Rosaliac Anti-Redness Intense Serum

Obagi Hydrate

Meder Beauty Salva Derm moisturiser

Sente Ultranourishing Cream

Heliocare Mineral Tolerance Fluid or their A-R Emulsion

Intradermology Synergy 6

La Roche-Posay Anthelios SPF50+

The Vichy range of sunscreens

This is the Sali Hughes article Fiona mentions: https://www.theguardian.com/fashion/2015/aug/29/rosacea-treatments-that-work-sali-hughes

Clarins’ Sensitive Skin Beauty Repair Concentrate is mentioned

Sophie mentions the Byonik laser https://illuminateskinclinic.co.uk/treatment/byonik-laser

We do have clinical studies that show a link between gut health and rosacea – here’s one https://www.dermatologytimes.com/view/skin-microbiota-linked-with-systemic-disease-rosacea

Lex Gillies on Insta is @talontedlex

Try Oxygenetix's foundation

Also… Rosalique 3 in 1 Anti-Redness Miracle Formula SPF 50

You could also try Avène Tinted Mineral Fluid SPF50+

Mentioned in this episode:

Hair loss | hair thinning | hair health

Tue, 26 Mar 2024 05:05:00 +0000

Dr. Sophie Shotter

Dr Sophie and Fiona discuss:

• What causes alopecia? • Genetic hair loss • The role of dihydrotestosterone (DHT) • The role of diet and medications • Over-processing / styling • Traction alopecia / braids • Dyson’s new range of dryers and straighteners • The role of hormones: childbirth, (peri)menopause, PCOS • The role of stress • Trichotillomania • Hair loss caused by auto immune disease • The work of Angela Christiano • JAK inhibitors • The role of the immune system • Isolated white patches of hair / trauma / shock • Gut health (see study info below) • COVID and hair loss • Hair re-growth after chemotherapy • Treatments – including… • Minoxidil • Finasteride • Laser therapy • Home LED devices • PRP • Stem cell therapy • The Trichotest (advanced DNA testing) • Blood tests to check for micronutrient deficiencies • The Keravive by HydraFacial • Hair transplants • Biotin • Viviscal Hair Growth Supplements • Do hair growth shampoos work? • How often should we wash our hair? • Scalp massage • Products available • Olaplex and lilial (what we know so far) • Dr Sophie’s favourite hair products and hairdresser

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Dr Sophie and Fiona mention a few brands, people, and studies – all the links are here (press ‘episode website’ for the full list):

The Manta hairbrush

Dyson’s range of products

Luke Hersheson’s products

Philip Kingsley’s Tricho 7 Scalp Drops

More on the work of Dr Angela here: https://magazine.medlineplus.gov/article/close-to-home-nih-researcher-and-alopecia-patient-seeks-a-cure#:~:text=Treatment%20breakthroughs-,Dr.,But%20not%20all%20people.

There have been reports linking hair loss to dust mites, cytomegalovirus, or Epstein-Barr virus – and the role of the microbiome. Read more: https://www.actasdermo.org/en-alopecia-microbiome-a-future-therapeutic-articulo-S1578219021001487

Dr Sophie offers:

The Trichotest (advanced DNA testing)

Calecim Professional stem cell therapy

Viviscal Hair Growth supplements (has around 10 published clinical studies)

She highly recommends https://giellygreen.co.uk/ in London – especially Jordan Favier

Dr Sophie recommends:

MONPURE’s Follicle Boost Hair Density Serum

The K18 hair range

Dr Sophie also mentions…

KeraHealth that uses a patented technology ingredient

Philip Kingsley's PK4 – a soya-based supplement

Nue Co's hair growth supplement

More on the Olaplex story here: https://www.bbc.co.uk/news/health-64662934

Mentioned in this episode:

How to get the best night’s sleep of your life

Fri, 15 Mar 2024 14:47:00 +0000

Dr. Sophie Shotter

Dr. Sophie and Fiona discuss:

• New data on the link between poor sleep and poor health • What happened when the light bulb was invented • Bright light and the circadian rhythm • Burn-out / work / sleep deprivation • How much sleep we really need • Sleep deprivation and the skin / accelerated ageing • What is good sleep hygiene? • Caffeine • Alcohol • Evening exercise and cortisol • Body temp • Blue light / screen time / melatonin • Devices in the bedroom • Circadian rhythm • Night owls / morning larks • REM sleep • The Oura ring (+ Kim Kardashian + Gwyneth Paltrow on socials) • Sleep apps • Insight Timer’s sleep stories • Weighted blankets • Sunrise alarm clocks and other types of alarm • Sleep ear buds • Temp controlled mattresses • VR sleep head sets / Therabody Smart Goggles • Space masks • Sensate (+ the vagus nerve) • The Apollo wristband • Magnesium • CBD • Dreem Distillery • 5 HTP • Ashwagandha • The role of glycine • The availability of melatonin in the UK (versus the US) • Blue light / amber light / device use • The Dodow device • ASMR • Lofi ASMR • Coloured noises (white noise etc) • Nature / forest / rainfall sounds • Sleep and hormones • Progesterone • The DUTCH test • Silk pillowcases – and sleep lines / bed head • Napping – good for longevity • Dr. Sophie’s espresso nap hack! • Working night shifts • Jet lag • Black-out blinds • The Time shift app

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Dr Sophie and Fiona mention a few studies – all the links are here (press ‘episode website’ for the full list):

The link between good sleep and good health. Read more: https://medicine.yale.edu/news-article/poor-sleep-may-increase-markers-of-poor-brain-health-new-study-finds/#:~:text=Poor%20Sleep%20May%20Increase%20Markers%20of%20Poor%20Brain%20Health%2C%20New%20Study%20Finds,-January%2029%2C%202024&text=Sleeping%20too%20much%20or%20too,life%2C%20a%20new%20study%20suggests.

How much sleep do we really need? Read more: https://www.sleepfoundation.org/how-sleep-works/how-much-sleep-do-we-really-need#:~:text=Most%20healthy%20adults%20need%20at,happy%2C%20healthy%2C%20and%20sharp.

Napping and longevity. Read more: https://www.theguardian.com/science/2023/jun/20/short-daytime-naps-may-keep-brain-healthy-as-it-ages-study-says

Mentioned in this episode:

Active skincare proven to work on lines and wrinkles

Tue, 12 Mar 2024 05:05:00 +0000

Dr. Sophie Shotter

Dr. Sophie and Fiona discuss:

• What causes lines and wrinkles? • Peptides – a brief intro • Retinoids • Peptides – more info • How peptides work and the different types • Peptides v retinoids • x2 peptide creams Dr. Sophie loves • How peptide creams can work where injectables can’t • Ceramides (why it’s important) • Understanding the role of hyaluronic acid • AHAs and BHAs and other acids • Protecting the skin barrier (esp with acids / retinoids) • PHAs and bionic PHAs (gentler acids) • Bakuchiol (a gentler exfoliant) • Ceramide supplements • The data on peptides v retinoids • Alastin’s unique approach to skincare • Different peptides will do different things • Dr. Sophie’s recommendations • Is this product worth the huge TikTok hype? • Is there a ‘hero’ product out there?! • Product overwhelm / the choices available • How the medical brands work (versus big-name brands) • A brand working uniquely on peri-meno skin • Can you get away with using just skincare actives? • A focus on ageing healthily

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Dr Sophie and Fiona mention a few brands, ideas, studies and individuals – all the links are here (press ‘episode website’ for the full list):

A 2019 study on women over the age of 40 found that the topical application of peptides created "significant improvements in skin wrinkles" in just two weeks. Read more here: https://www.mdpi.com/1422-0067/21/1/73

Dr. Sophie recommends:

Meder Beauty Mio Fix

Revision Skincare Revox Line Relaxer

[these next ones are mentioned later in the podcast but we’re putting all the recommendations in one place]

Skin Better Science AlphaRet Overnight Cream (plus the eye version)

Skin Better Science Interfuse Intensive Treatment LINES

SkinCeuticals HA intensifier

This is Indeed Labs’ best-seller with the snoxin that Dr. Sophie mentions https://indeedlabs.com/collections/fine-lines-wrinkles/products/snoxin-ii

Vichy – Mineral 89

Medik8’s retinoids

Dr. Sophie LOVES https://www.revisionskincare.co.uk/products/d-e-j-face-cream?gad_source=1&gclid=CjwKCAiAi6uvBhADEiwAWiyRdvi5K1-F5sxZHLRVvfOZp2A4MLXkx_PCLrAbHXKwmGLhLOrQXvT6AhoClxIQAvD_BwE

Dr. Sophie mentioned two particular PHAs called gluconolactone and lactobionic acid (the latter derived from milk) – these are gentler alternatives to AHAs, BHAs, retinoids and even glycolic and salicylic acid.

Bakuchiol is an antioxidant found in the leaves and seeds of the psoralea corylifolia plant. This is also an alternative to AHAs, BHAs, retinoids etc.

This is the Alastin skincare technology Dr. Sophie mentioned: https://alastin.com/pages/trihex-ingredient

Dr. Sophie responds to the hype re this product from The Ordinary https://theordinary.com/en-gb/argireline-solution-10-serum-100403.html?gad_source=1&gclid=CjwKCAiAi6uvBhADEiwAWiyRdhg0oHPH2QS-4-EzAp7_7jEKh1QUYWunkBW58Di58oHlZERfryTgCRoCEh8QAvD_BwE&gclsrc=aw.ds

A quick guide from Elle UK on the different types of peptides https://www.elle.com/uk/beauty/skin/a45735491/peptides/

The brand Dr. Sophie mentions that has a unique action with oestrogen and MEP technology https://emepelle.co.uk/pages/the-science-of-emepelle-and-mep

Mentioned in this episode:

Are you ready for skin boosters yet?

Tue, 05 Mar 2024 05:05:00 +0000

Dr. Sophie Shotter

The American Elle magazine article Fiona mentions:

https://www.elle.com/beauty/makeup-skin-care/a43552346/what-is-profhilo/

Some of the brands Dr. Sophie offers include:

Profhilo

Croma PhilArt

Volite (SKINVIVE in the USA)

Viscoderm Hydrabooster (great for the forehead and around the mouth)

Other brands Dr. Sophie offers:

Sunekos (with amino acids)

Sculptra

Dr. Sophie personally uses Profhilo (inc on her decolletage) and polynucleotides around the eyes and she loves / uses Volite (inc. around her neck).

Dr. Sophie talks about biostimulators for the body including Sculptra; Lanluma; and Lenisna.

Some more useful information: https://drsophieshotter.com/everything-you-need-to-know-about-polynucleotides/

Mentioned in this episode:

All-things EYES (wrinkles / supp's / peri-meno + vision)

Tue, 27 Feb 2024 05:05:00 +0000

Dr. Sophie Shotter

Dr. Sophie and Fiona discuss:

• The cause(s) of crow's feet • Crow's feet and…the role of muscle relaxing injections • Crow's feet and…the role of poly nucleotides and / or fillers • Crow's feet and…what devices can achieve • The cause(s) of bags under the eyes • Bags under the eyes and…hyaluronic acid fillers • Bags under the eyes and…what devices can achieve • Bags under the eyes and…budget / at-home remedies • Bags under the eyes and…the role of sleep • The cause(s) of dark circles • Dark circles and… eye creams • Retinoid-based eye creams (and other actives) • Dark circles and make-up hacks • Dark circles and…laser treatments • Dark circles and…chemical peels • Eye surgery • The results Dr. Sophie sees in clinic • Face lifts (in relation to the eyes) • The causes of puffiness around the eyes • Puffiness and… budget / at-home remedies • Puffiness and…eye creams • Dr. Sophie’s eye cream regime (and product recommendations) • How we sleep / pillow hygiene • Sunken eyes (and when to contact a GP) • Sunken eyes and…fillers • The importance of eye tests • An anecdote on why they’re so critical / emergency laser treatment • Droopy eye brows / eye lids • Droopy brows and…blepharoplasty surgery • Droopy brows and… ultrasound (and DATA) • Droopy brows and…muscle relaxing injections • Droopy brows and…fillers • Thread lifts (and why care is needed) • ‘Spocking’ / heaviness after muscle relaxing injections • Why some people aren’t suited to muscle relaxing injections • How hormones impact the eyes (lots of examples + tips) • Perimenopause and the eyes (lots of info + tips) • x2 more anecdotes – floaters + a bang to the head (delayed eye impact) • Things you can do at home • Lymphatic drainage • How to use eye creams • Supplements – and data • Carrots and vitamin A • How to look after your eyes • Screen time / sunglasses / sleep

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en …and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Dr Sophie and Fiona mention a few brands, ideas, studies and individuals – all the links are here (press ‘episode website’ for the full list):

Bobbi Brown has a range of colour correctors – match to your shade then apply concealer on top: https://www.bobbibrown.co.uk/product/14018/15905/makeup/face-and-cheek/corrector-and-concealer/corrector#/shade/Light_Bisque

Dr. Sophie’s eye routine:

In the morning:

She alternates between

https://shop.illuminateskinclinic.co.uk/product/revox-line-relaxer-20ml/

https://shop.illuminateskinclinic.co.uk/product/myo-fix-frown-control-concentrate-15ml/

Then she’ll use https://shop.illuminateskinclinic.co.uk/product/d%c2%b7e%c2%b7j-eye-cream/ on top of either of the above.

At night:

https://www.skinbetter.com/shop-skincare/product-category/eye-care/eyemax-alpharet-overnight-cream-M009.html#tab=description

There are studies to say that sleeping on your back is better. If that feels uncomfortable, try a medical-grade pressure-release pillow, like the Envy pillow. https://www.envypillow.com/

Dr. Sophie recommends:

https://ziipbeauty.com/products/ziip-halo

https://www.flaviamorellato.co.uk/

In one study, Vitamin E has been shown to help reduce the onset of cataracts – read more here https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3051399/#:~:text=Vitamin%20E%20is%20a%20lipid,membranes%20(12%2D15).

There have been several studies on some of the B Vitamins which have shown their benefit to eye health. Especially Vitamin B12, Vitamin B9 and Vitamin B6. These may play a role in conditions such as AMD (age-related macular degeneration), this was highlighted in the Women’s Antioxidant and Folic Acid Cardiovascular Study (WAFACS).

Thiamine (also known as Vitamin B1) has been shown to reduce and slow down the rate of developing cataracts.

Omega 3 oils have been shown to be effective in treating dry eyes by helping the natural production of a healthy tear film.

Lutein and zeaxanthin are the only dietary carotenoids found in the retina. According to a 2006 study, people who consume a diet that’s low in lutein and zeaxanthin may be at a higher risk for developing cataracts. https://pubmed.ncbi.nlm.nih.gov/16936087/

According to a 2016 study, lutein may help reduce dry eye symptoms. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4800098/

Vitamin A - along with beta carotene - has been studied in relation to reducing the development of cataracts and AMD.

This is the brand Fiona uses (as recommended by her optician) https://www.boots.com/hycosan-extra-preservative-free-eye-drops-7-5ml-10172236

Dr Sophie mentioned this laser treatment https://lumenis.co.uk/vision/products/optilight/

Studies show there’s been an increase in myopia in children since COVID. It’s thought this is because of increased screen time and children developing a focal plane that’s only close up. Read more: https://bjo.bmj.com/content/early/2021/07/15/bjophthalmol-2021-319307

Mentioned in this episode:

'Regenerative aesthetics': the next-gen of skincare

Tue, 13 Feb 2024 05:05:00 +0000

Dr. Sophie Shotter

Dr. Sophie and Fiona discuss:

• What is regenerative aesthetics? • New data - ageing skin releases inflammatory mediators into the bloodstream • NEW - treatments that stimulate collagen and elastin • Harmonyca – how it goes beyond traditional fillers / bio stimulators • Bio stimulators – an explainer • NEW - devices that stimulate collagen and elastin • Sofwave • Radiofrequency micro-needling • The role of collagen supplements • NEW injectable – polynucleotides – stimulates stem cells • Juvalook – hyaluronic acid and PDLLA – and the eyes • NEW – gene therapy (and early-stage trials) • NEW – stem cell therapy (and products) • Human stem cells skincare versus plant ‘stem cell’ skincare • Growth factors as ‘stem cells’ in plant-based products • Synthetic products • What do human-based stem cell skincare products actually contain? • How many of the treatments are permanent? • What about downtime? • NEW - using exosomes in skincare • Exosomes – an explainer • Studies on exosomes – how they can regenerate skin and hair growth • Exosomes – topical versus injectables • Exosome skincare brands • South Korea – stem cell banking • NEW – how wrinkle relaxers are evolving • NEW – skincare ingredients to look out for • Sunflower sprout extract – how it works • Skincare that changes how a cell behaves • Dr Sophie’s go-to product • NAD+ as a skincare ingredient • How best to biohack your skin • Dr Sophie’s skincare protocols • Skincare with vitamin C and niacinamide • The role of sleep • The treatments Dr Sophie has • Skincare trends • ‘Prejuvenation’ • Body-care • High-performing plant-derived active ingredients • Microbiome-based skincare • Sustainability in skincare – formulations and packaging • Suncare innovations • AI in aesthetics (robots that inject wrinkle relaxers) • How AI can enhance the industry • The importance of human expertise • Neuro-glow (and mental health)

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en …and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Dr Sophie and Fiona mention a few brands, ideas, studies and individuals – all the links are here:

First, this is the Harpers Bazaar article that Dr Sophie contributed to: https://www.harpersbazaar.com/uk/beauty/a46114525/2024-beauty-trends/

There are several studies that indicate how ageing skin releases inflammatory mediators into the bloodstream – here’s one example:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082169/

https://drsophieshotter.com/harmonyca-is-this-injectable-the-future-of-fillers/

https://juvelook.uk/ (Dr Sophie later talks about results here with the eye area)

https://lenisna.uk/

More on the new types of filler (e.g. PLLA and PCL) here: https://drsophieshotter.com/what-is-a-collagen-stimulating-filler/

https://www.sculptrausa.com/

https://ellanse.com/

https://radiesse.com/how-it-works/

Dr Sophie uses >> https://sofwave.com/

https://inmodemd.com/workstation/morpheus8/

https://candelamedical.com/products/profound/

https://cutera.co.uk/secretRF#:~:text=secrectRF%20%7C%20Non%2DSurgical%20Facial%20Resurfacing%20%7C%20CUTERA (Secret RF)

Dr Sophie uses >> https://candelamedical.com/products/matrix/

https://drsophieshotter.com/everything-you-need-to-know-about-polynucleotides/

Dr Sophie uses >> https://www.cromapharma.com/uk/about-croma/press-and-downloads/croma-pharma-further-strengthening-its-portfolio-with-biostimulators/

Studies on exosomes include:

https://www.sciencedirect.com/science/article/abs/pii/S1389172323003262 (hair) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10296902/ (skin)

Dr Sophie uses >> https://aestheticmanagementpartners.com/exo-e/ (EXO-E)

Also mentioned > https://en.drsturm.com/exoso-metic-face-serum/

https://morphiya.com/

On sunflower sprout extract >> https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5622016/#:~:text=The%20sunflower%20seed%20and%20sprout,%2C%20and%20vitamins%20%5B2%5D.

Dr Sophie uses >> https://www.revisionskincare.co.uk/products/d-e-j-daily-boosting-serum%E2%84%A2

Dr Sophie uses >> https://nuchido.com/blogs/news/meet-dr-nichola-conlon-the-founder-of-nuchido

The Swedish sleep study https://www.bmj.com/content/341/bmj.c6614

Some brands mentioned:

https://luna-daily.com/

https://www.biojuve.co.uk/

https://www.laroche-posay.co.uk/

https://go.redirectingat.com/?id=127X618962&url=https%3A%2F%2Fdcypher.me%2F&xs=1&xcust= (Dcypher – AI-powered foundation brand)

https://renude.co/ - AI-trained to identify a range of skin concerns

The skincare platform https://klira.skin/ offers epigenetic skin typing.

Mentioned in this episode:

The supplements ep - a new approach to vitamins, adaptogens, nootropics + herbs

Tue, 30 Jan 2024 05:10:00 +0000

Dr. Sophie Shotter

Dr. Sophie and Fiona discuss:

• Vit C and liposomal delivery • Vit C as a therapeutic supplement • The link between Vit C and collagen • Vit C and telomeres • Vit D and MS / long COVID • Types of vitamin D (and taking with vitamin K) • Magnesium (inc the link with stress / good sleep) • B vitamins – challenges with a plant-based diet • B12 and mental health • Omegas • Alpha-ketoglutarate • Ashwagandha (and stress) • CBD • Glutathione • MCT – the brain and memory • Creatine • Amino acids • Black cohosh and red clover (HRT alternatives?) • Women who’ve had breast cancer • Phyto-oestrogens • Milk thistle • St. John's wort • Spermidine • NAD+ • Resveratrol • Smart drugs (nootropics) • L-theanine and the brain / creativity (+ calming impacts?) • Bacopa Monnieri and memory • Curcumin and quercetin (and cancer) • Berberine • Iodine • Charcoal

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en …and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Dr Sophie and Fiona mention a few brands, ideas, studies and individuals – all the links are here:

Supplement / brands mentioned and used / recommended by Dr Sophie…

https://www.surreycentrefornaturalhealth.com/evernutri-supplements.html

https://www.altrient.com/

https://www.allergyresearchgroup.com/vitamin-d3-complete-veggie-softgels/

https://www.metagenics.com/omegagenics-epa-dha-1000

https://oxfordhealthspan.com/#:~:text=Recommended%20by%20world%2Dleading%20longevity,concentrated%20Japanese%20wheat%20germ%20extract.

https://nuchido.com/pages/nad-supplements

https://timehealth.co.uk/product/ca-akg/

https://dreemdistillery.co.uk/

https://otowellbeing.com/pages/spa

https://strongnutrients.com/products/pure-creatine?variant=36449563508901

https://www.symprove.com/ (probiotics not mentioned in this ep as it was covered in December but this is the brand Sophie always recommends)

Other stuff including further reading and studies…

Dr. Sophie’s Get The Gloss article: https://www.getthegloss.com/health/live-longer-tips-sophie-shotter

The link between vitamin C and collagen https://lpi.oregonstate.edu/mic/health-disease/skin-health/vitamin-C#:~:text=Specifically%2C%20vitamin%20C%20has%20been,response%20to%20photodamage%20(48)

Studies on therapeutic vitamin C:

https://www.imperial.nhs.uk/about-us/news/latest-remap-cap-results

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9295384/

https://jeccr.biomedcentral.com/articles/10.1186/s13046-021-02134-y

https://www.frontiersin.org/articles/10.3389/fnut.2023.1025936/full

Studies on therapeutic vitamin D:

https://www.mssociety.org.uk/research/explore-our-research/emerging-research-and-treatments/vitamin-d

https://www.theguardian.com/lifeandstyle/2021/jan/10/does-vitamin-d-combat-covid

https://www.thelancet.com/journals/landia/article/PIIS2213-8587(18)30265-1/fulltext#:~:text=Our%20findings%20suggest%20that%20vitamin,lower%20doses%20of%20vitamin%20D.

Magnesium and anxiety https://www.healthdirect.gov.au/blog/can-magnesium-help-to-reduce-anxiety#:~:text=The%20good%20news%20is%20that,calming%20effect%20on%20the%20body.

Oxford study on B12 deficiency in male vegans https://www.bdi.ox.ac.uk/publications/65908

B12 deficiency and mental health / depression / dementia https://pubmed.ncbi.nlm.nih.gov/35337631/#:~:text=Vitamin%20B12%20deficiency%20can%20have,screening%20of%20at%2Drisk%20populations.

A good article on omegas (inc. advice for those on a plant-based diet) https://www.vogue.in/beauty/content/what-do-you-really-need-to-look-for-in-your-omega-3-supplement

The link between omega 3’s, mood, and cognitive function https://bmjopen.bmj.com/content/9/6/e027167

Metformin as a supplement https://fortune.com/well/2023/05/04/metformin-anti-aging-longevity-risks-side-effects/

The Bradley Cooper film discussed is https://en.wikipedia.org/wiki/Limitless_(film)

This is an interesting supplement (NOTE: not tried or verified by Dr Sophie): https://www.wildnutrition.com/products/pure-strength-omega-3

And this is also an interesting supplement (NOTE: not tried or verified by Dr Sophie) https://www.thenakedpharmacy.com/products/saffrosun-calm-1

Info on ashwagandha:

https://www.healthline.com/nutrition/ashwagandha#safety-and-side-effects

This is an interesting supplement with both ashwagandha and magnesium (NOTE: not tried or verified by Dr Sophie) https://lifearmour.co.uk/products/super-me-capsules

One of many CBD studies: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6326553/#:~:text=At%20the%20first%20monthly%20assessment,in%20anxiety%20and%20sleep%2C%20respectively.

This is an interesting CBD alternative with PEA (NOTE: not tried or verified by Dr Sophie) https://youthandearth.com/collections/cbd-alternative/products/pea-60-capsules?variant=43663716679893

Lots of great info and resources on fasting and autophagy are online via Dr. Mindy Pelz - get googling!

Coconut oil contains numerous MCTs and this has been shown in an older in-vitro study to reduce the growth of Candida (which causes thrush) by 25%. MCT has also been shown to have antimicrobial and antifungal effects. Some researchers suggest it might have certain anti-inflammatory effects, but more studies are needed. Read more here: https://www.healthline.com/nutrition/mct-oil-benefits#TOC_TITLE_HDR_2

In one study, people who supplemented with 8 grams of creatine per day for five days reduced mental fatigue during mathematical calculations, compared to those taking a placebo. Similarly, a review of 6 studies found that 5–20 gram doses could improve short-term memory.

Info on creatine loading

https://www.menshealth.com/nutrition/a28339030/creatine-loading/

Plus read https://www.womenshealthmag.com/uk/fitness/strength-training/a42178665/creatine/

Text that follows below is from this article:

https://drsusanloveresearch.org/alternatives-to-hrt-complementary-care/

A study found that 70% of postmenopausal women who took 40mg black cohosh for 12 weeks reported a decrease in menopausal symptoms, including hot flashes but was no placebo group to compare this with and it was only 150 women taking part. The question for breast cancer survivors is whether it is estrogenic. On this front we actually have some data. Firstly, there’s no known phytoestrogen in black cohosh – and there’s no evidence that black cohosh binds to the estrogen receptor. In a petri dish, breast cancer cells were exposed to black cohosh in the absence of estrogen, in the presence of estrogen, and in the presence of tamoxifen. They found that the black cohosh given alone inhibited cell growth. When estrogen was added it blunted the growth usually seen and it enhanced the effects of tamoxifen. This effect has been replicated in four other studies on cell lines. Studies in women have confirmed this lack of estrogenic effect.

NOTE: The Cancer Research UK site tells us you shouldn’t take black cohosh if you: • have breast cancer • have liver or kidney problems • have blood pressure problems or take medicines for your blood pressure • are pregnant or breastfeeding • And it lists several meds so do check with your GP or look at their website

Red Clover is another commonly used herb marketed for hot flashes and menopausal symptoms. There have been two randomized controlled studies comparing it to placebo but neither study found that red clover was better than the placebo. There is concern about its ability to stimulate breast cancer, but this has not been studied.

Some research suggests that St John's wort works in a similar way to standard antidepressant medication, by increasing the activity of brain chemicals such as serotonin and noradrenaline (thought to play an important part in regulating our mood). But some research suggests that it can make feelings of anxiety worse for some people. Experiences vary from person to person and more research needs to be done.

Milk thistle info: https://www.healthspan.co.uk/advice/body/the-effects-of-milk-thistle-on-the-menopause/

L-Theanine firstly is a naturally occurring amino acid found in tea, but it can also be taken as a supplement. L-theanine is even more effective when taken with caffeine and taking even just 50 mg — the amount found in roughly two cups of brewed tea — has been found to increase alpha-waves in the brain, which are linked to creativity. Several studies have also shown that taking 200 mg of L-theanine has a calming effect, without causing drowsiness.

Bacopa monnieri is a herbal supplement that has been shown to improve memory and information processing when taken for several months.

Panax ginseng root is an ancient medicinal plant used to boost brain function. Taking a single dose of 200–400 mg of Panax ginseng has been shown to reduce brain fatigue and significantly improve performance on difficult tasks like mental math problems. Some longer-term studies have found that your body may adapt to ginseng, making it less effective after several months of use. So more research is needed on its long-term nootropic effects.

This supp is interesting https://youthandearth.com/collections/anti-aging/products/preservage?variant=36505456738467 (NOTE: not tried or verified by Dr Sophie)

Info on Jane McLelland and her approach to cancer (she used various supplements but also off-licence meds) – mentioned by Fiona – this is for information only (not endorsed by Dr Sophie) https://www.lifeextension.com/magazine/2020/1/wellness-profile

Iodine. This brand talks about the fact that (quoting) “recent research shows the UK is one of just two high-income countries with iodine deficiency issues, and has a worse rate than some developing countries. This is largely linked to diet and poor intake of iodine rich foods (white fish, dairy and seaweeds of the right kinds).” – here is its range: https://doctorseaweed.com/collections/supplements (NOTE: not tried or verified by Dr Sophie)

This is also interesting https://youthandearth.com/collections/improved-skin-complextion/products/irish-sea-moss-bladder-wrack?variant=43757230948565 (NOTE: not tried or verified by Dr Sophie)

Mentioned in this episode:

The surprising magic of mushrooms

Tue, 16 Jan 2024 05:10:00 +0000

Dr. Sophie Shotter

Dr. Sophie and Fiona discuss:

• How mushrooms help skin • Beta glucan • Adaptogens • Kojic acid and hyperpigmentation • Reishi’s anti-inflammatory (and hydrating) properties • Tremella (snow mushroom) and hyaluronic acid • Reishi • Mycelium and sustainable beauty • Stella McCartney’s mushroom leather bag • Origins and the iconic Mega Mushroom treatment oil • Other brands using mushrooms • Mushrooms as a supplement – inc. the immune system / cognitive function • Mushrooms and glutathione (antioxidant) – plus liver function • Lion’s mane – and anxiety and depression / sleep • Mushroom extraction processes • Different supplementation brands • Understanding reishi’s potential side effects • Curcumin and cellular health • Green tea and EGCG

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en …and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Dr Sophie and Fiona mention a few brands, ideas, studies and individuals – all the links are here:

Reishi inhibits the melanin-producing enzyme tyrosinase so is helpful in reducing skin pigmentation and discoloration.

A 2016 study found that mushrooms helped combat ageing, reduce skin disease inflammation and correct hyperpigmentation.

A 2019 study found that the beta-glucan in mushrooms helps improve the skin barrier and fight ageing with antioxidants.

https://www.sciencedirect.com/science/article/abs/pii/S092666901630396X

https://digitalaesthetics.co.uk/news/news/mushrooms-in-the-beauty-industry#:~:text=A%202016%20Study%20on%20Industrial,and%20fight%20ageing%20with%20antioxidants.

In the UK, a company called Magical Mushroom uses mycelium to create packaging for various brands.

Boots Botanicals range uses mushrooms in its micellar water.

Kiehl’s uses sustainably grown chaga to help even out skin tone and boost radiance in its Super Multi-Corrective Cream.

Charlotte Tilbury used mushroom extract in her foundation back in 2016.

Meder Beauty’s Red-Apax Concentrate contains a truffle called Albatrellus ovinus extract, also called northern truffle, and this has been formulated to combat redness / rosacea, and has been proven to reduce discoloration and calm skin. Meder also have mushrooms also in their Equaderm cream.

SkinBetter has tremella in its TechNO neck perfecting cream and white mushroom extract in its EyeMax cream.

The Neostrata Dark Spot Corrector has Kojic acid.

Murad has mushrooms in their Invisiblur Perfecting Shield SPF 30.

Paula’s Choice has mushrooms in the Super Hydrate Overnight Mask.

And there’s an interesting looking cleanser by Kora - milky mushroom cleansing oil. There are also niche, boutique brands such as FRWRD Skincare whose hero product is the Organic Mushroom Super Serum which also promises to calm sensitive skin, reducing redness and breakouts.

Shroom Skincare have blended four mushroom extracts into its Mycelium Glow: Vitamin C & Mushroom Brightening Serum.

Neon Hippie uses a proprietary seven-mushroom complex for its range.

Youth to the People’s Adaptogen Deep Moisture Cream uses fermented reishi and ashwagandha.

Herbar is another new mushroom-based skincare brand.

A.P. Chem is an interesting one as it uses what it calls Alt-Pharma ingredients including Polyglutamic Acid and GABA (both found in mushrooms). Their MicroDose Magical Moisturizer has a bit of a cult following and received coverage from Oprah.

We mentioned K beauty on our skincare episode - BioRepublic is a Korean beauty–inspired skincare brand that uses snow mushrooms in its organic sheet masks.

Alicia Keys has mushrooms in her skincare range which has been developed by dermatologists. Her Promise Serum uses snow mushroom, with zinc and vitamin B3.

Q+A Zinc PCA Facial Serum is made with reishi and shiitake and it’s (currently) only £9 so good for a budget buy.

Ren’s Redness Relief Serum uses white mushroom extract and is very popular with those who have rosacea.

More info…

Mushrooms are high in glutathione, an antioxidant and detoxifying nutrient, as well as ergothioneine, which protects DNA from oxidative damage. Plus mushroom polysaccharides have a significant impact on the immune system and are even said to fight viruses, bacteria and other pathogens.

Reishi has been shown to help de-stress and create deeper, better sleep – but only if used regularly.

Lion's mane has typically been used in supplements for brain health, but Origins are said to be looking at developing formulations for topical use because of its antioxidant benefits.

Some other hero ingredients include:

Ashwaganda – it’s been claimed it can reduce anxiety by up to 44%. Chaga - contains vast amounts of antioxidants and is praised for boosting immunity and slowing down the ageing process. Maca - is linked to libido and sexual function. Shilajit – is said to balance sex hormones.

Lots of these are available in powders that can be added to smoothies or coffee or foods.

Always look for certified organic mushrooms that have been “extracted” – that’s key to making sure you’re getting the highest quality with maximum efficacy.

Wunder Workshop combine different adaptogens for their super powders.

GROWN liquid supplements can either be added to drinks or placed straight onto the tongue.

Other brands include: Bristol Fungarium

Dirtea

The Nue Co Nootro Focus

Kiki Health Organic Lion’s Mane Extract Mushroom

Inessa Immunity Complex

WelleCo The Super Elixir - Daily Greens Pouch Refill

Indi Supplements

Grass and Co

Research demonstrates that curcumin activates certain proteins that help delay cellular senescence and promote longevity. Plus, some studies demonstrate that it combats cellular damage and significantly increases life span, postponing age-related disease and symptoms.

Green tea contains a polyphenol called Epigallocatechin gallate (EGCG). EGCG restores mitochondrial function in cells and acts on pathways involved in aging. It also induces autophagy, the process by which the body removes damaged cellular material.

Plus, there may be an association between green tea intake and protection against aging skin, as well as reduced hyperpigmentation caused by ultraviolet (UV) light.

Aesthetics + self-esteem + feminism + new regulations (and more)

Tue, 02 Jan 2024 11:57:00 +0000

Dr. Sophie Shotter

Dr. Sophie and Fiona discuss:

• The ‘male gaze’ in films and TV • Is it possible to be a feminist and have injectables? • The language of looking good [for your age] • Self esteem • Body dysmorphic disorder • The critical importance of a consultation • New attitudes to ageing • Saying no to a client • Managing clients’ expectations • Avoiding the overdone or ‘done’ look • Are aesthetic treatments too accessible? • A serious lack of UK regulations in aesthetics • Cheap packages that aren’t (always) safe • Does everyone want to look the same? • The role of social media and filters • Celebrities and surgery (their right to privacy?) • Robbie Williams • Affordability • People’s fear of injectables • Keeping treatments and tweakments a secret • Men and aesthetics • Body dysmorphic disorder (see below for support)

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en …and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

The gut + the skin + the vaginal microbiome + cellular ageing

Tue, 19 Dec 2023 05:10:00 +0000

Dr. Sophie Shotter

Dr. Sophie and Fiona discuss:

• The connection between good gut health and skin • The skin’s microbiome – should we really be double cleansing? • The impact of skin treatments such as Roaccutane / antibiotics • Gut health and longevity / cellular ageing • Probiotics (the strains you need) • Candida… and IBS • Spore based / soil based probiotics • The vaginal microbiome • Prebiotics • Digestive enzymes • Eating bread • Taking probiotics while on antibiotics • Gut health testing / Zoe / the SIBO test • Acupuncture • Fasting, autophagy, mitophagy • The vagus nerve • Cold water therapy

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en …and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Dr Sophie and Fiona mention a few brands, ideas, studies and individuals – all the links are here:

Research linking gut dysbiosis to acne, rosacea, eczema, psoriasis, and other skin conditions. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7916842/

Gut health and acne https://zoe.com/learn/gut-health-and-acne

Two thirds of our immune system lives in our gut https://www.uclahealth.org/news/want-to-boost-immunity-look-to-the-gut

A study that indicates isotretinoin (another name for Roaccutane) has no significant (negative) impact on gut microbes https://pubmed.ncbi.nlm.nih.gov/28689869/

Research suggests the health of our gut microbiome largely determines how we will age and the diseases we will either acquire or avoid. https://www.nature.com/articles/nature25973

PLUS

https://link.springer.com/article/10.1007/s12602-021-09903-3#:~:text=Studies%20have%20shown%20that%20gut,disorders%20is%20also%20becoming%20apparent

Re probiotics: the two main strains you want to look for are: lactobacillus and bifidobacterium. Within these two, there are a lot of different strains.

https://www.symprove.com/ < Dr. Sophie's recommendation

A healthy vaginal microbiome should be dominated by a good bacteria called lactobacilli, especially the species called lactobacillus crispatus. Some people say that Saccharomyces boulardii really helps candida – it’s a yeast that fights yeast but while it’s helpful for some, others don’t tolerate it well. Read more: https://www.optibacprobiotics.com/uk/professionals/latest-research/gut-health/probiotics-best-for-candida#:~:text=S.,from%20the%20digestive%20tract2%20.

Fiona's acupuncturist: John Chadwick (Sidmouth, Devon): johnchadwick@ymail.com

An interesting listen: https://podcasts.apple.com/gb/podcast/the-junk-food-doctor-this-food-is-worse-than-smoking/id1291423644?i=1000632239649

https://www.hollandandbarrett.com/the-health-hub/vitamins-and-supplements/supplements/inulin-powder-supplement/

https://www.verywellhealth.com/the-benefits-of-digestive-enzymes-89446

https://zoe.com/

SIBO testing is available in several places such as here: https://healthpath.com/sibo-breath-test/?utm_term=sibo%20test&utm_campaign=SIBO+-+Exact&utm_source=adwords&utm_medium=ppc&hsa_acc=5004928523&hsa_cam=6449023587&hsa_grp=77317475015&hsa_ad=382201416429&hsa_src=g&hsa_tgt=kwd-306464899573&hsa_kw=sibo%20test&hsa_mt=e&hsa_net=adwords&hsa_ver=3&gad_source=1&gclid=Cj0KCQiA67CrBhC1ARIsACKAa8QSdxixKMR9ftSiPCJVan_quuR1D9cn4X_LjE07Yn0Nzv0AmJOqj3EaAnAfEALw_wcB

Vagus nerve ear massage https://www.youtube.com/watch?v=9uZ1rnKF5DU

Mentioned in this episode:

Dr Sophie’s acne protocol

Tue, 05 Dec 2023 05:10:00 +0000

Dr. Sophie Shotter

Dr. Sophie and Fiona discuss:

• Is acne on the increase (if so, why)? • Girls, women, hormones - and acne • Testosterone / HRT regimes • Cortisol • Dairy • GI loads in diet • The gut health connection • Skin care products • Fungal acne • Niacinamide • Budget skincare ranges • Soolantra • Roaccutane • Antibiotics • Spironolactone • In-clinic treatments • Scarring • DIM (diindolylmethane) • Emergency spot treatments • The mental health factor

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en …and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Dr Sophie and Fiona mention a few brands, ideas, studies and individuals – all the links are here:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788264/

https://www.jaad.org/article/S0190-9622(16)30480-7/fulltext#sec4

https://www.health.com/condition/acne/stress-acne

https://clinisoothe.com/?utm_source=google&utm_medium=cpc&utm_campaign=13952991541&gclid=Cj0KCQiAr8eqBhD3ARIsAIe-buPEDl7J_6KDoM_OwRxFMoC3U92ATvlSdQJH90NGnsCmsXT5wq45nk4aAj5bEALw_wcB

https://www.aad.org/public/diseases/acne/causes/diet

https://zoe.com/learn/gut-health-and-acne

https://www.cerave.com/skincare/acne

https://www.laroche-posay.co.uk/en_GB/effaclar-2

https://www.bioderma.co.uk/skincare/sebium

https://www.nhs.uk/medicines/isotretinoin-capsules/

https://practicaldermatology.com/articles/2014-jan/on-dosage-and-diet-isotretinoin-101

https://www.rosacea.org/patients/causes-of-rosacea/demodex-mites-and-microbes

https://www.bmj.com/content/381/bmj.p1114

https://aviclear.com/

https://www.allure.com/story/aviclear-review

https://zitsticka.co.uk/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8354339/#:~:text=Many%20studies%20showed%20high%20prevalence,psychiatric%20comorbidities%20in%20chronic%20diseases. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8354339/

Further studies and reading

https://jddonline.com/articles/the-role-of-benzoyl-peroxide-in-the-new-treatment-paradigm-for-acne-S1545961613S0073X/#:~:text=Combining%20BP%20with%20a%20topical,resistant%20strains%20of%20P%20acnes.

https://www.theguardian.com/fashion/2019/oct/05/the-best-emergency-spot-treatments

https://www.theguardian.com/lifeandstyle/2011/aug/19/sali-hughes-acne-treatments

Mentioned in this episode:

Skincare products, ingredients - and heroes

Tue, 28 Nov 2023 05:10:00 +0000

Dr. Sophie Shotter

Dr. Sophie and Fiona discuss:

• Squalane • Single ingredient products • Vitamin C (inc. stability and dose / formulations) • Niacinamide • Budget friendly vitamin C products • Exfoliating acids (inc. what Dr Sophie uses) • How to exfoliate • Hyaluronic acid • Serums - the lowdown • Dr Sophie’s favourites • Cult products • Alcohol denat • SPF (mineral and chemical) • Neck creams, decolletage, eye creams, night creams • Retinol – the explainer • New molecules and developments in skincare • Exosomes • Dr. Sophie’s skincare heroes • New business models / Beauty Pie • Multitasking skincare v single ingredient products • Skin cycling • Korean skincare • Dr Sophie’s routine • Can any skincare remove wrinkles? The data • A holistic approach

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en …and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Dr Sophie and Fiona mention a few brands, ideas, studies and individuals – all the links are here:

https://biossance.com/products/100-squalane-oil

https://www.laroche-posay.co.uk/en_GB/toleraine-1?start=0&sz=24

https://www.paulaschoice.co.uk/clinical-ultra-rich-moisturizer/m5570.html?dwvar_m5570_size=fullsize&cgid=pregnancy-skincare&reviews=&pr_rd_page=1&aw_account=1510415071&aw_campaign=19592213249&aw_adgroup=&aw_creative=&aw_dev=c&aw_target=&&utm_content=performance_max&gad_source=1&gclid=CjwKCAjw7oeqBhBwEiwALyHLM-cNYfOib6WC4dTz2P8-zmzBfKm7GXFJG5czLgQdm9NIIL8hKKKc9hoCxT8QAvD_BwE

https://www.revisionskincare.co.uk/?gad_source=1&gclid=CjwKCAjw7oeqBhBwEiwALyHLMzsnmPxDtNDdrQn4jtjMDvshIja52__h9o6MQer4ZrRe67IqJmiBjhoCe7sQAvD_BwE

https://skindiligent.com/products/vitamin-c-serum-in-oil

https://www.medik8.com/products/c-tetra

https://www.vichy.co.uk/en_GB/liftactiv-supreme-15-pure-vitamin-c-brightening-serum-20ml/VICUK-140.html

https://www.neostrata.com/products/collections/restore

https://mederbeauty.com/products/enzy-peel-double-action-exfoliating-mask?variant=44619262263570

https://www.vichy.co.uk/en_GB/mineral-89-hyaluronic-acid-hydrating-serum---hypoallergenic-for-all-skin-types/VICUK-014.html

https://www.vichy.co.uk/en_GB/mineral-89-probiotic-serum/VICUK-135.html

https://mederbeauty.com/products/hydra-fill-concentrate

https://www.revisionskincare.co.uk/products/hydrating-serum

https://www.neostrata.com/products/aging/tri-therapy-lifting-serum/F30159XA.html

https://www.skinbetter.com/shop-skincare/product-category/antioxidants/alto-advanced-defense-and-repair-serum-M006.html

https://www.skinceuticals.co.uk/en_GB/c-e-ferulic-vitamin-c-antioxidant-serum-for-visible-signs-of-ageing-30ml/S17.html

https://www.esteelauder.co.uk/product/689/77491/product-catalog/skincare/repair-serum/advanced-night-repair-serum/synchronized-multi-recovery-complex

https://www.clarins.co.uk/double-serum/C070400090.html

https://www.drunkelephant.co.uk/gb/en/collections/serums/

Sophie references avoiding alcohol denat. Here’s a useful article from Paula’s Choice (referencing data and science): https://www.paulaschoice.co.uk/alcohol-in-skincare-the-facts

The efficacy and safety of sunscreen use for the prevention of skin cancer - PMC (nih.gov)

https://heliocare.co.uk/products/mineral-tolerance-fluid

https://www.esthederm.com/en/suncare/by-range/solar-range.html

https://www.laroche-posay.co.uk/en_GB/sun-care-face

https://www.revisionskincare.co.uk/collections/treat-neck/products/nectifirm-advanced

https://www.skinbetter.com/shop-skincare/product-category/neck-care/techno-neck-perfecting-cream-M013.html

The Medik8 range in three sections:

https://www.medik8.com/collections/shop-by-retinol https://www.medik8.com/collections/shop-by-retinaldehyde https://www.medik8.com/collections/shop-by-retinyl-retinoate

A retinol alternative if you’re pregnant:

https://edit.sundayriley.com/alternatives-to-retinol-during-pregnancy/ https://www.skinbetter.com/shop-skincare/product-category/anti-aging/alpharet-overnight-cream-M001.html

https://amp-uk.co.uk/exoe/

https://www.obagi.com/

Two new skincare launches to look out for:

https://sentelabs.com/

https://www.biojuve.co.uk/

https://www.beautypie.com/

The ones Sophie always has in the rotation:

https://www.revisionskincare.co.uk/products/d-e-j-daily-boosting-serum%E2%84%A2?_pos=1&_sid=35655adf0&_ss=r&gad_source=1&gclid=CjwKCAjw7oeqBhBwEiwALyHLM1LXfuwrcGrGrOW05wulykZ99fQc6Nq6_IXid-51ppcNNNXS8nS5XhoCJMsQAvD_BwE https://www.revisionskincare.co.uk/products/c-correcting-complex-30?gad_source=1&gclid=CjwKCAjw7oeqBhBwEiwALyHLM0qGLtVUmk3X_rTk_tLIvFzLrqhaSAL3m7EZk8bdZRd3nrrJ-qioUhoCVEsQAvD_BwE

https://www.revisionskincare.co.uk/products/c-correcting-complex-30?gad_source=1&gclid=CjwKCAjw7oeqBhBwEiwALyHLM0qGLtVUmk3X_rTk_tLIvFzLrqhaSAL3m7EZk8bdZRd3nrrJ-qioUhoCVEsQAvD_BwE

https://www.neostrata.com/products/aging/tri-therapy-lifting-serum/F30159XA.html

https://www.skinbetter.com/shop-skincare/product-category/anti-aging/alpharet-overnight-cream-M001.html

https://www.skinbetter.com/shop-skincare/product-category/eye-care/eyemax-alpharet-overnight-cream-M009.html

https://www.revisionskincare.co.uk/collections/treat-neck/products/nectifirm-advanced

https://mederbeauty.com/collections/sheet-masks

https://mederbeauty.com/products/enzy-peel-double-action-exfoliating-mask?_pos=2&_sid=4094c872b&_ss=r&variant=44619262263570

The alternatives to injectables:

https://mederbeauty.com/products/myo-fix-concentrate?variant=44619261870354

https://revisionskincare.com/products/revox%E2%84%A2-line-relaxer-0-68-fl-oz

https://www.skinbetter.com/shop-skincare/product-category/anti-aging/interfuse-intensive-treatment-lines-M005.html

Mentioned in this episode:

At-home gadgets and devices

Tue, 21 Nov 2023 05:10:00 +0000

Dr. Sophie Shotter

Dr. Sophie and Fiona discuss:

• LED masks – in-clinic versus at-home (and the data) • Sophie’s preferred at-home option • Different LED lights and what they do • The Dermalux Flex • LED hype v LED data • Budget options for LED • At home microcurrent devices • What microcurrent can and can’t do • Taking a multi-pronged approach with gadgets and injectables • Radiofrequency – at home versus in-clinic • The Body Balancer – and cellulite • Budget options • Jade rollers, gua sha, ice wands, rollers • Lymphatic drainage massage (and a recommendation) • Body brushing and bamboo tappers • Buccal massage • Micro-needling at home? • The cult behind of the Clarisonic • The skin’s microbiome • Dr Sophie’s recommendations

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en …and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Dr Sophie and Fiona mention a few brands, ideas, and individuals – all the links are here:

https://dermaluxled.com/device/flex-md/

https://www.lustreclearskin.com/

https://www.newabeauty.co.uk/products/newa-starter-kit

https://bodyballancer.co.uk/

https://www.charlottetilbury.com/uk/product/cryo-recovery-face-mask

https://dimple-amani.com/

https://dimple-amani.com/products/kansa-wand

Mentioned in this episode:

Dr. Sophie's collagen 101

Tue, 14 Nov 2023 05:00:00 +0000

Dr. Sophie Shotter

Dr Sophie and Fiona discuss:

• Collagen – a simple explainer • The different types of collagen • The real impact of collagen loss • How stress impacts collagen production (see links below) • What type of collagen should we use? • Dosage information and guidance • Brand recommendations • Hydrolysed collagen • Sources • Is vegan collagen a thing? • The role of vitamin C • Injectables • Other recommendations • Collagen banking • What you can do in-clinic • How long before you'll start seeing results? • When to take collagen • Can pregnant women take it? • Men and collagen • Face creams

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en …and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Dr Sophie and Fiona mention a few brands, ideas, studies and individuals – all the links are here:

An independent study from 2019 that found collagen supplements do show promise in terms of improving skin elasticity and dermal collagen density > https://jddonline.com/articles/dermatology/S1545961619P0009X

Dr Sophie’s recommendations:

https://evernutri.com/products/evercol

https://www.absolutecollagen.com/

https://feelingenious.com/

https://www.altrient.com/liposomal-vitamin-c

https://www.doseandco.com/uk

This is the collagen that’s only available through nutritionists (with a type 2) https://evernutri.com/products/omnicol%E2%84%A21-10-hydrolysed-collagen TO BUY, PLEASE USE THIS CODE: SophieSREvernutri

Mentioned in this episode:

The ultimate guide to biohacking

Mon, 23 Oct 2023 16:42:17 +0000

Dr Sophie Shotter

Dr Sophie and Fiona discuss:

• Biohacking – an explainer • What’s evidence-based (or not)? • The role of influencers versus expert knowledge • Light therapy (infrared / LED) • Collagen supplements • Clean beauty • Micro needling • Oxygen therapy / hyperbaric oxygen • Skin cell therapy • Oestrogen • IV vitamin C and long COVID • NAD+ (brand linked in below) • Sleep • Vitamin D3 • Magnesium • Oura Ring (linked in below) • Glucose monitoring • Meditation • Nutrition and alcohol • Forest bathing • Fasting and Dr Mindy Peltz / John Hopkins (linked in below) • Perimenopause • Cryotherapy • Home DNA analysis • The Dutch test

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en …and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Dr Sophie and Fiona mention a few brands, ideas and individuals – all the links are here:

https://nuchido.com/pages/nad-supplements

https://ouraring.com/

https://drmindypelz.com/

https://www.hopkinsmedicine.org/health/wellness-and-prevention/intermittent-fasting-what-is-it-and-how-does-it-work

The content in this podcast is for general informational purposes only and is not meant to serve as medical advice or to replace or substitute advice given by, or consultation with, your doctor or any other healthcare professional. Please contact your healthcare provider if you have any questions or concerns about your health. Dr Sophie Shotter, her company and any employees or representatives are not liable for any claims arising out of or in connection with this podcast.

Mentioned in this episode:

How to slow down ageing

Mon, 23 Oct 2023 16:36:23 +0000

Dr Sophie Shotter

Dr Sophie and Fiona discuss:

• Health span over life span • How to measure your biological age (link below) • The longevity discussion in-clinic • Adjacent positive impacts of exercise • Good sleep hygiene • Dr Sophie’s evening routine… • … and supplements • Vitamin C’s link to collagen production (research below) • NAD+ • Magnesium • Vitamin D3 • Omega 3’s, inflammation and cognitive function (study below) • Vegan options with omega oils • Resveratrol • Metformin (details of study below) • Spermidine - and autophagy (brand linked in below) • Gut health and skincare (study below) • We can intervene in the ageing process (see Dr David A Sinclair site below) • Epigenetics • DNA tests that calculate our biological age • Telomeres – an explainer • Mental health and micro dosing (TED talk linked in below) • Meditation • Dr. Joe Dispenza (info below)

Find out more by heading to https://drsophieshotter.com/

Follow Dr Sophie on Instagram… https://www.instagram.com/drsophieshotter/?hl=en

…and Tik Tok https://www.tiktok.com/@drsophieshotter?lang=en

This podcast was produced by https://thepodcastpeople.co/

Dr Sophie and Fiona mention a few brands, ideas and individuals – all the links are here:

The link between vitamin C and collagen https://lpi.oregonstate.edu/mic/health-disease/skin-health/vitamin-C#:~:text=Specifically%2C%20vitamin%20C%20has%20been,response%20to%20photodamage%20(48)

The link between omega 3’s, mood, and cognitive function https://bmjopen.bmj.com/content/9/6/e027167

Metformin https://fortune.com/well/2023/05/04/metformin-anti-aging-longevity-risks-side-effects/

Spermidine supplement https://oxfordhealthspan.com/#:~:text=Recommended%20by%20world%2Dleading%20longevity,concentrated%20Japanese%20wheat%20germ%20extract.

The link between gut health and good skin https://www.sciencedirect.com/science/article/pii/S2352647515000155

Bio Kult probiotics https://www.bio-kult.com/

Symprove probiotic https://www.symprove.com/

Read about Dr David A Sinclair’s work https://lifespanbook.com/

Test your biological age https://glycanage.com/

‘Why We Sleep’ by Matthew Walker https://www.waterstones.com/book/why-we-sleep/matthew-walker/9780141983769

TED talk on microdosing https://youtu.be/vQuuY9xmzjg?si=k85jak3T2YQW02PU

Michael Pollan's How to Change Your Mind https://michaelpollan.com/books/how-to-change-your-mind-uk/#:~:text=%E2%80%9CHow%20to%20Change%20Your%20Mind%E2%80%9D%20is%20a%20calm%20survey%20of,%2Dreporting%2C%20a%20giant%20square.

Dr Joe Dispenza https://drjoedispenza.com/

Mentioned in this episode:

Age Well with Dr Sophie Shotter: NOW LIVE!

Mon, 23 Oct 2023 15:44:44 +0000

Conversations with the award-winning Dr Sophie Shotter covering the latest trends and developments in skincare, longevity, and aesthetics - bringing a science-based approach, and a focus on inner health and wellness.

Mentioned in this episode:

Age Well with Dr Sophie Shotter

Why we don't have a vitamin C skincare product with Tiina Meder from Meder Beauty

Hyperbaric oxygen and why people are using it - from serious disease to chronic insomnia – with Alan Trim

A chat with Emilie Lavinia - The Independent's Fitness and Wellbeing Editor

The anxiety guide inc. a full CBD oil explainer + anti-anxiety supplements

Dr Louise Oliver on women and mid-life snoring

Jo Hurley on the vaginal + semen microbiome - the test, the interventions, the protocols

The nervous system ‘calm’ device that Sophie swears by - and a review of the latest health tech and wearables

The UK's leading expert Dr Sharon Wong on hair loss, hair shedding, and eczema

"MCAS and histamine intolerance are so prevalent - yet most people have never heard of either" - Dr Tina Peers

My incredible chat with Jo Woodhurst from Ancient and Brave

USA supplements ‘tourism’ – the latest melatonin headlines – and a possible new pathway for Alzheimer’s

Why soil based probiotics are so different, and so powerful – with Katie Ward from Microbz

The wellness trends to watch in 2026

Dr Sophie's 2025 favourite things (from skincare to supplements and everything in-between)

A chat with leading sleep guru Kathryn Pinkham (let's all improve our sleep in 2026!)

A super quick peptides explainer (and the peptide products that should be on your Christmas list)

Why spermidine is the longevity supplement going mainstream in 2026 - with Primeadine’s Leslie Kenny

Why 2025 saw a blepharoplasty boom - with Dr Elizabeth Hawkes

Ayahuasca, psychedelics, and Dr Joe Tafur's journey from trained doctor to the Peruvian Amazon

Ashwagandha. Is it the ultimate stress fixer + the facts behind the Danish ban

Sarah Bradden’s incredible story of recovery – and how this led to The Bradden Method

What's in my kit - from make-up artist Emma Rankin

How I recovered from long COVID - Dr Tam Lewis

Dr Nichola Conlon on ageing well - and figuring out our biological age

The truth about low testosterone and why so many men need TRT - with Dr Jeff Foster

What we now know about eggs, sperm, and fertility (new data, new ideas)

Grounding sheets (and how an insomniac got their "best ever night's sleep")

A chat with cult facialist and skincare visionary... Sarah Chapman

Metformin + ivermectin + rapamycin (etc) << a ‘longevity’ drugs explainer

How to radically improve your digital nutrition - with Dr Kaitlyn Regehr

NEW data / thinking on insulin – from Alzheimer’s to PCOS - Prof Ben Bikman

Viagra + Cialis + NEW options for female libido (and does Viagra lower the risk of Alzheimer’s?)

Dr Stacy Sims - the world's leading voice on why women need to exercise differently to men

Why the science world is getting *so* excited about post-biotics (short explainer)

Forget everything you know about taking magnesium and other mineral supp's - and meet Caroline Alan

Ozempic and other weight loss drugs - the headlines, the concerns, and *everything* you need to know

Chemicals in personal care and cleaning products. Should we be worried?

All things breast surgery (and is breast implant illness a thing?) - Nora Nugent

Meta Cell Technology (MCT): is this the biggest skincare breakthrough in years?

Signs of thyroid issues + an iodine explainer + the menopause link

Product favourites w/ journalist and Beauty Director Alessandra Steinherr

A 20 minute creatine explainer inc. new findings on mental health

New data on snacking + protein + sweeteners + early colorectal cancer (and more) – ZOE's Prof Sarah Berry

The ultimate guide to happy, healthy hair – Tom Smith

How to build a skincare brand that blends science with soul - Annee de Mamiel

A new approach to the pelvic floor + a protein powder designed for women – Rachel Prince

How I recovered from PCOS + an autoimmune disease – and became pregnant - Liberty Mills

The Magic of Mushrooms – Part 2 – Andrew Salter (Dirtea)

Lifting weights is the panacea of longevity - Claire Sanderson

In Paris they appreciate a midlife woman – Lisa Armstrong OBE

The Beauty Triangle, entrepreneur life - and an incredible acupuncture story - Francesca Ogiermann-White

Navigating a new phase of womanhood - Trish Halpin

How to reinvent when life throws a curve ball - Jo Elvin

The Magic of Mushrooms - Part 1 - Tom Baxter (Bristol Fungarium)

The Priorities Method - and how to figure out what it is you really want - Lily Silverton

How we're navigating mid-life - Annabel Rivkin and Emilie McMeekan

Unpacking the buzz around 'deep plane' - a more natural approach to face lifts - Marc Pacifico

Over 35 yrs in beauty... this is my routine and my must-have products - Nadine Baggott

I've seen data that this is transforming women's vaginal health - Dr Zoe Williams

Avoiding fame, finding zen, and why I haven't seen myself in 'Love Actually' - Sienna Guillory

I've tried every treatment / tweakment going; this is what works - Alice Hart Davis

My ultimate make-up recommendations and tips – Caroline Barnes

What a beauty editor loves, uses, and rates - Rosie Green

How I built a £30m brand with collagen as the hero - Maxine Laceby

How yoga nidra transformed my nervous system - Victoria Woodhall

Skin tracking - is this the future of ageing well?

Slow down and breathe - with Rob Rea

Sugar + sweeteners (the latest thinking, gurus, products, and data)

Sure, give up caffeine – but not coffee. Here’s why.

Bath oils | PJs | CBD | candles | hair | make-up | skincare > Dr Sophie's favourite things

Meet Prof David Nutt and find out how cannabis is radically changing lives

Meet Nick Birch and find out why women need to take their bone health *way* more seriously

Meet Smita Sinha and find out how she's transforming women's vaginal and vulval health

Meet Dr Bita Fox and find out why her work on oral health has become so important

A review of at-home health test kits

Is tap water ok? + water filters explained + the buzz around 'wellness water'

Infrared explained

The latest data on how to radically improve your brain health (inc. 'menopause brain')

Cold water therapy (and how it's transforming menopausal mood swings, anxiety, and hot flushes)

Why the science world is getting so excited about post-biotics (short explainer)

Ozempic and other weight loss drugs - the headlines, the concerns, and everything you need to know

Meet Nick Birch and find out why women need to take their bone health way more seriously

“From sex drive to fertility – this is a men's health pandemic." – Dr Tracy Gapin guest ep

“We now have hard evidence that THIS will slow cellular ageing" - Dr Nichola Conlon guest ep

"Yes, I take sides in couples therapy. Here's why..." - Terry Real guest ep

“Loss of nitric oxide is directly linked to almost every chronic disease” – Dr Nathan Bryan guest ep

“Psychedelic drugs are creating profound change for trauma and addiction” – Tracey Tee guest ep

"Do not bring your phone into the bedroom!" - Boniface guest ep

"This is how to train your brain - and improve your memory" - Prof Mark D'Esposito guest ep

"I shot up to 1 million - then 2 million followers" - Danae Mercer on going viral guest ep

"This is why our poop matters" - ZOE's Dr Will Bulsiewicz guest ep

The supplements ep - a new approach to vitamins, adaptogens, nootropics + herbs