RELAY Podcast - Dementia Researcher Vodcast

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We gratefully acknowledge the support of our funders: Alzheimer’s Association, Race Against Dementia, Alzheimer’s Research UK, Alzheimer’s Society, and the National Institute for Health and Care Research.

The views and opinions expressed by guests in this podcast are their own and do not necessarily reflect those of the producers, funders, or sponsors.

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RELAY Podcast - Diversity and Disparities PIA

Thu, 17 Jul 2025 00:00:00 +0100

In this episode, Professor Owen Carmichael talks with Dr Shana Stites, Assistant Professor at University of Pennsylvania and Chair of the ISTAART Diversity and Disparities PIA. In this discussion they explore the importance of inclusive participation in dementia research, the challenges of equitable access to research and care, and the shift toward more community-engaged approaches. The conversation highlights barriers like limited access to healthcare, the ethics of stipends, and the value of transparency, reciprocity, and representation in Alzheimer's disease and related research. They also talk about the wider work and aims of the PIA and what they have planned for the upcoming AAIC.

There are currently 30 PIAs covering a wide range of interests and fields, from the PIA to Elevate Early Career Researchers to Biofluid Based Biomarkers and everything in between.

A transcript of this show, links and show notes and profile on all our guests are available on our website at https://www.dementiaresearcher.nihr.ac.uk.

If you prefer to watch rather than listen, you will find a video version of this podcast on Apple Podcasts, YouTube, and on our website.

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The views and opinions expressed by guests in this podcast are their own and do not necessarily reflect those of the producers, funders, or sponsors.

Subscribe to our sister show 'Dementia Researcher The Blogs':

https://podfollow.com/dementia-researcher-blogs

RELAY Podcast - Nutrition, Metabolism and Dementia PIA

Wed, 16 Jul 2025 00:00:00 +0100

In this episode, Professor Natalie Phillips interviews Professor Owen Carmichael, Director of Biomedical Imaging at Pennington Biomedical Research Center and incoming chair of the ISTAART Nutrition, Metabolism, and Dementia PIA. Owen shares his journey from computer science to neuroscience, and how his imaging work investigates how diet and metabolism shape dementia risk. They explore the promise of precision nutrition, the challenges of studying lifelong dietary exposure, and the vital role of olfaction and sensory health in nutrition. The episode also discusses the importance of inclusive research and lifelong data to understand and prevent cognitive decline. The show rounds-up the PIAs upcoming work at the AAIC, and the work of the PIA.

There are currently 30 PIAs covering a wide range of interests and fields, from the PIA to Elevate Early Career Researchers to Biofluid Based Biomarkers and everything in between.

A transcript of this show, links and show notes and profile on all our guests are available on our website at https://www.dementiaresearcher.nihr.ac.uk.

If you prefer to watch rather than listen, you will find a video version of this podcast on Apple Podcasts, YouTube, and on our website.

Leave us a tip:

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Download and Register with our Community App:

The views and opinions expressed by guests in this podcast are their own and do not necessarily reflect those of the producers, funders, or sponsors.

Subscribe to our sister show 'Dementia Researcher The Blogs':

https://podfollow.com/dementia-researcher-blogs

RELAY Podcast - Sensory Health and Cognition PIA

Tue, 15 Jul 2025 00:00:00 +0100

In this episode, Dr Marta del Campo interviews Natalie Phillips, Chair of the Sensory Health and Cognition PIA and Professor of Psychology at Concordia University. Together, they discuss the role of hearing, vision, and olfaction in cognitive ageing and dementia risk. They explore mechanisms behind these links, from cognitive load to social isolation, and discuss emerging biomarker research, challenges in clinical implementation, and how this new ISTAART PIA is fostering interdisciplinary collaboration. The episode also previews upcoming activities at AAIC and highlights opportunities for early career researchers to get involved.

There are currently 30 PIAs covering a wide range of interests and fields, from the PIA to Elevate Early Career Researchers to Biofluid Based Biomarkers and everything in between.

A transcript of this show, links and show notes and profile on all our guests are available on our website at https://www.dementiaresearcher.nihr.ac.uk.

If you prefer to watch rather than listen, you will find a video version of this podcast on Apple Podcasts, YouTube, and on our website.

Leave us a tip:

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The views and opinions expressed by guests in this podcast are their own and do not necessarily reflect those of the producers, funders, or sponsors.

Subscribe to our sister show 'Dementia Researcher The Blogs':

https://podfollow.com/dementia-researcher-blogs

RELAY Podcast - Biofluid Based Biomarkers PIA

Mon, 14 Jul 2025 00:00:00 +0100

In this Relay Podcast episode, Dr Colin Groot interviews Dr Marta Del Campo, Head Fluid Biomarker Facility; Ramón y Cajal Research fellow at BarcelonaBeta Brain Research Center and chair of the ISTAART Biofluid Based Biomarkers PIA. Together, they talk about recent advances in fluid biomarkers in dementia research, and explore the growing role of plasma biomarkers, integration with clinical trials, challenges with reproducibility and diversity, and the promise of proteomics and AI. Marta also reflects on the work of ISTAART, their plans for AAIC, the value of publishing negative findings, and why ISTAART offers vital opportunities for early career researchers.

There are currently 30 PIAs covering a wide range of interests and fields, from the PIA to Elevate Early Career Researchers to Biofluid Based Biomarkers and everything in between.

A transcript of this show, links and show notes and profile on all our guests are available on our website at https://www.dementiaresearcher.nihr.ac.uk.

If you prefer to watch rather than listen, you will find a video version of this podcast on Apple Podcasts, YouTube, and on our website.

Leave us a tip:

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Download and Register with our Community App:

The views and opinions expressed by guests in this podcast are their own and do not necessarily reflect those of the producers, funders, or sponsors.

Subscribe to our sister show 'Dementia Researcher The Blogs':

https://podfollow.com/dementia-researcher-blogs

RELAY Podcast - Atypical Alzheimer's Disease PIA

Sun, 13 Jul 2025 00:00:00 +0100

In this episode, Dr Alexa Pichet-Binette interviews Dr Colin Groot, an expert in neuroimaging and atypical Alzheimer's disease from Amsterdam University Medical Centre. They discuss the clinical and biological diversity within atypical variants such as posterior cortical atrophy (PCA), language and behavioural forms, and CBSAD. Colin shares insights into ongoing studies on tau PET, mortality, subtyping PCA, and how ISTAART’s Atypical PIA is pushing forward international collaboration and inclusivity in clinical trials and diagnostic criteria.

There are currently 30 PIAs covering a wide range of interests and fields, from the PIA to Elevate Early Career Researchers to Biofluid Based Biomarkers and everything in between.

A transcript of this show, links and show notes and profile on all our guests are available on our website at https://www.dementiaresearcher.nihr.ac.uk.

If you prefer to watch rather than listen, you will find a video version of this podcast on Apple Podcasts, YouTube, and on our website.

Leave us a tip:

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Download and Register with our Community App:

The views and opinions expressed by guests in this podcast are their own and do not necessarily reflect those of the producers, funders, or sponsors.

Subscribe to our sister show 'Dementia Researcher The Blogs':

https://podfollow.com/dementia-researcher-blogs

ISTAART Relay Podcast - Nonpharmacological Interventions PIA

Fri, 19 Jul 2024 00:00:00 +0100

Welcome to the last show in this season of the ISTAART PIA Relay Podcast, presented by Dementia Researcher. In our final episode, we come full circle with Dr Keir Yong, Senior Research Fellow at UCL's Dementia Research Centre, speaking with Professor Arlene Astell, Chair of the Non-Pharmacological Interventions PIA.

Professor Astell discusses her role as a Professor of Cyber Psychology at Northumbria University and Director of the Dementia Ageing Technology Engagement Lab at the University of Toronto. She offers a comprehensive look into her journey into dementia research, sparked by early interactions with individuals living with dementia, and her commitment to understanding and mitigating the cognitive and behavioural challenges they face.

Gain insights into the innovative projects led by Professor Astell, including the development of touchscreen computer systems designed to support conversation for people with dementia. How the significance of lifestyle interventions, such as nutrition and physical activity, and the emerging potential of neuromodulation can play a role in reducing dementia risk.

The conversation also highlights the broader implications of non-pharmacological interventions, the challenges in implementing these approaches within health systems, and the importance of influencing public health policy to ensure wider adoption – and the role that the Non-Pharmacological Interventions PIA can play in fostering collaboration.

A transcript of this show, links and show notes and profile on all our guests are available on our website at https://www.dementiaresearcher.nihr.ac.uk.

If you prefer to watch rather than listen, you will find a video version of this podcast on Apple Podcasts, YouTube, and on our website.

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The views and opinions expressed by guests in this podcast are their own and do not necessarily reflect those of the producers, funders, or sponsors.

Subscribe to our sister show 'Dementia Researcher The Blogs':

https://podfollow.com/dementia-researcher-blogs

ISTAART Relay Podcast - Atypical Alzheimer's Disease PIA

Thu, 18 Jul 2024 00:00:00 +0100

Join us for another episode of the ISTAART Relay Podcast brought to you by Dementia Researcher. We’re releasing one of these shows each week in the build up to the AAIC, which this year starts on the 28th July.

In this episode, Dr Diana Karamacoska takes over the hot seat to interview Dr Keir Yong, a Senior Research Fellow at University College London, about the intricacies of Atypical Alzheimer's Disease, and the work of the Atypical Alzheimer's Disease PIA.

Discover how posterior cortical atrophy (PCA), a less common variant of Alzheimer’s, impacts patients' lives and the innovative research aiming to improve diagnosis and treatment. Get insights into the diagnostic challenges, the role of biomarkers, and the essential interdisciplinary collaborations driving advancements in this field.

Don't miss this deep dive into Keir’s work, hot topics in the field, and how their PIA is making a difference.

A transcript of this show, links and show notes and profile on all our guests are available on our website at https://www.dementiaresearcher.nihr.ac.uk.

If you prefer to watch rather than listen, you will find a video version of this podcast on Apple Podcasts, YouTube, and on our website.

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The views and opinions expressed by guests in this podcast are their own and do not necessarily reflect those of the producers, funders, or sponsors.

Subscribe to our sister show 'Dementia Researcher The Blogs':

https://podfollow.com/dementia-researcher-blogs

ISTAART Relay Podcast - Partnering with Research Participants PIA

Wed, 17 Jul 2024 00:00:00 +0100

Join us for another episode of the ISTAART Relay Podcast from Dementia Research. This time Dr Ece Bayram moves from interviewee to interviewer and chats with Dr Diana Karamacoska, the vice chair of the Partnering with Research Participants PIA.

This episode explores the challenges and breakthroughs in dementia research, with a special focus on engaging underserved communities, and public involvement. Dr Karamacoska shares her personal journey inspired by her grandparents' experiences with dementia, highlighting the gaps in services and the importance of culturally appropriate care.

Discover how the ISTAART PIAs are transforming dementia research through meaningful partnerships and inclusive practices. Learn about the global shift towards collaboration with research participants and the innovative approaches being used to address disparities in dementia care. Diana also discusses the significance of maintaining well-being while working closely with affected communities and the role of the PIA in supporting researchers.

Tune in to explore the latest trends, including the exciting initiatives planned for the upcoming Alzheimer's Association International Conference (AAIC) in Philadelphia, and understand why the Partnering with Research Participants PIA is unique in its dedication to patient and public involvement.

A transcript of this show, links and show notes and profile on all our guests are available on our website at https://www.dementiaresearcher.nihr.ac.uk.

If you prefer to watch rather than listen, you will find a video version of this podcast on Apple Podcasts, YouTube, and on our website.

Leave us a tip:

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The views and opinions expressed by guests in this podcast are their own and do not necessarily reflect those of the producers, funders, or sponsors.

Subscribe to our sister show 'Dementia Researcher The Blogs':

https://podfollow.com/dementia-researcher-blogs

ISTAART Relay Podcast - Lewy Body Dementias PIA

Tue, 16 Jul 2024 00:00:00 +0100

In this episode of the ISTAART Relay Podcast, Dr Jessica Caldwell, a neuropsychologist and director at the Cleveland Clinic, interviews Dr Ece Bayram, the newly appointed assistant professor and incoming communications chair for the ISTAART Lewy Body Dementias PIA.

They explore Ece’s research on sex differences in genetics and environmental risk factors for Lewy body dementia. Ece shares insights into her innovative projects, the work of their PIA, plans for the upcoming AAIC and the significance of understanding sex and gender differences in neurodegenerative diseases, and the importance of designing research with community involvement. They also discuss the challenges of conducting studies in diverse populations and the need for global collaboration.

Tune in to hear about the exciting developments in Lewy body dementia research and the impact of community-driven studies on advancing the field.

A transcript of this show, links and show notes and profile on all our guests are available on our website at https://www.dementiaresearcher.nihr.ac.uk.

If you prefer to watch rather than listen, you will find a video version of this podcast on Apple Podcasts, YouTube, and on our website.

Leave us a tip:

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The views and opinions expressed by guests in this podcast are their own and do not necessarily reflect those of the producers, funders, or sponsors.

Subscribe to our sister show 'Dementia Researcher The Blogs':

https://podfollow.com/dementia-researcher-blogs

ISTAART Relay Podcast - Sex and Gender Differences in Alzheimer's Disease PIA

Mon, 15 Jul 2024 00:00:00 +0100

Welcome to the fifth season of the ISTAART PIA Relay Podcast, brought to you by Dementia Researcher. In this six-part series, members of ISTAART professional interest areas (PIAs) take turns interviewing their colleagues about the latest research in Alzheimer's disease and other dementias. This episode features a Caitlyn Fastenau, a PhD candidate from the University of Texas Health Science Centre interviewing Dr Jessica Caldwell, a neuropsychologist and director of the Women’s Alzheimer’s Movement Prevention and Research Centre at Cleveland Clinic.

Dr Caldwell discusses her pioneering work at the world's only clinic designed specifically for women to reduce their Alzheimer's risk, focusing on sex and gender differences in the disease. She highlights the critical role of menopause, stress, and hormonal changes in Alzheimer's risk and shares insights into the importance of diverse research populations and the unique challenges faced by women caregivers.

Tune-in as explore hot topics of sex and gender differences in Alzheimer's research, including the impact of menopause, the need for gender-diverse studies, and the initiatives of the ISTAART Sex and Gender Differences in Alzheimer's Disease PIA and what they have planned for AAIC. Whether you're a researcher, clinician, or someone affected by Alzheimer's, this episode offers valuable perspectives on the intersections of gender, health, and dementia.

A transcript of this show, links and show notes and profile on all our guests are available on our website at https://www.dementiaresearcher.nihr.ac.uk.

If you prefer to watch rather than listen, you will find a video version of this podcast on Apple Podcasts, YouTube, and on our website.

Leave us a tip:

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The views and opinions expressed by guests in this podcast are their own and do not necessarily reflect those of the producers, funders, or sponsors.

Subscribe to our sister show 'Dementia Researcher The Blogs':

https://podfollow.com/dementia-researcher-blogs

ISTAART Relay Podcast - Immunity and Neurodegeneration PIA

Sun, 14 Jul 2024 00:00:00 +0100

Welcome to the fifth season of the ISTAART PIA Relay Podcast, brought to you by Dementia Researcher. This series features members of ISTAART, engaging in insightful interviews about groundbreaking dementia research, and the work of the ISTAART Professional Interest Areas (PIA) they represent.

As we build up to the Alzheimer’s Association International Conference in Philadelphia, join us for daily episodes that showcase the remarkable work being done in various research fields.

In this episode, Professor Arlene Astell interviews Caitlyn Fastenau, a PhD candidate in Integrated Biomedical Sciences focusing on the Biology of Ageing. Caitlyn shares her journey into dementia research, driven by personal experiences and a passion for understanding neurodegenerative diseases. Her research explores the role of immune cells, particularly microglia, in Alzheimer’s disease, using advanced techniques like single-cell RNA sequencing.

Caitlyn discusses the her work, the importance of diversity in research, highlighting efforts to include underrepresented communities in dementia studies. She also talks about the significance of translational research and the potential non-pharmacological interventions that could reduce the risk of neurodegenerative diseases.

Tune in to learn more about the Immunity and Neurodegeneration PIA, what they have planned for AAIC and the latest hot topics in the field, and the collaborative environment that ISTAART provides for researchers at all levels.

PS. Don't miss Caitlyn's presentation at the AAIC and her insights on leveraging student engagement in scientific societies.

A transcript of this show, links and show notes and profile on all our guests are available on our website at https://www.dementiaresearcher.nihr.ac.uk.

If you prefer to watch rather than listen, you will find a video version of this podcast on Apple Podcasts, YouTube, and on our website.

Leave us a tip:

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Download and Register with our Community App:

The views and opinions expressed by guests in this podcast are their own and do not necessarily reflect those of the producers, funders, or sponsors.

Subscribe to our sister show 'Dementia Researcher The Blogs':

https://podfollow.com/dementia-researcher-blogs

ISTAART Relay Podcast - The Eye As A BiomarkerFor AD PIA

Fri, 14 Jul 2023 00:00:00 +0100

The Dementia Researcher, ISTAART Relay Podcast is back for a fourth series. Five leading researchers discussing their research, their field, and the work of the Alzheimer’s Association ISTAART Professional Interest Area they represent.

EP5 – Dr Shana D Stites interviews Dr Imre Lengyel representing The Eye as a Biomarker for AD PIA.

Shana Stites is an Assistant Professor at University of Pennsylvania. As a clinical psychologist and researcher with the Penn Project on Precision Medicine for the Brain (P3MB), Shana’s research focuses on advancing diagnosis and treatment of Alzheimer’s. The goal is to understand ways to promote quality of life and psychological wellbeing. This includes understanding the impacts of the disease on individuals who may be directly affected by pathology as well as their family members. As part of this work, Shana has a special focus on better understanding how aspects of identity, such as age, gender, and race, operate as determinants in the disease experience. Shana is representing the ISTAART Diversity & Disparities PIA.

Imre Lengyel is a Reader (Associate professor) at Queen’s University Belfast. Imre is researching how we could use the eye as a less expensive, better tolerated, and faster marker to monitor the progression of neurodegeneration. He undertakes clinical eye imaging and use postmortem tissues to generate molecular and high-resolution anatomical confirmation for the changes we see in eye images. Imre is representing the ISTAART The Eye as a Biomarker for AD PIA.

The Alzheimer’s Association International Society to Advance Alzheimer’s Research and Treatment (ISTAART) convenes the global Alzheimer’s and dementia science community. Members share knowledge, fuel collaboration and advance research to find more effective ways to detect, treat and prevent Alzheimer’s and other dementias. Professional Interest Areas (PIA) are an assembly of ISTAART members with common subspecialties or interests.

There are currently 29 PIAs covering a wide range of interests and fields, from the PIA to Elevate Early Career Researchers to Biofluid Based Biomarkers and everything in between.

To sign-up to ISTAART and a PIA visit:

Note: ISTAART Membership is free for students worldwide, and for researchers of all levels based in Low- and Middle-Income Countries.

https://aaic.alz.org

A transcript of this show, links and show notes and profile on all our guests are available on our website at https://www.dementiaresearcher.nihr.ac.uk.

If you prefer to watch rather than listen, you will find a video version of this podcast on Apple Podcasts, YouTube, and on our website.

Leave us a tip:

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Download and Register with our Community App:

The views and opinions expressed by guests in this podcast are their own and do not necessarily reflect those of the producers, funders, or sponsors.

Subscribe to our sister show 'Dementia Researcher The Blogs':

https://podfollow.com/dementia-researcher-blogs

ISTAART Relay Podcast - Diversity And Disparities PIA

Thu, 13 Jul 2023 00:00:00 +0100

EP4 – Dr David Cash interviews Dr Shana D Stites representing the Diversity & Disparities PIA.

Dave Cash is a Principal Research Fellow at University College London. Dave is a biomedical engineer that has worked predominantly in imaging (never let him near your wet lab if you like your glassware). His PhD involved image guided liver surgery at Vanderbilt University, and in 2005, he picked up and moved from the southern United States to London to do a post-doc. That led him to an opportunity to get involved in Alzheimer’s disease trials. Dave is representing the ISTAART Neuroimaging PIA.

There are currently 29 PIAs covering a wide range of interests and fields, from the PIA to Elevate Early Career Researchers to Biofluid Based Biomarkers and everything in between.

To sign-up to ISTAART and a PIA visit:

Note: ISTAART Membership is free for students worldwide, and for researchers of all levels based in Low- and Middle-Income Countries.

A transcript of this show, links and show notes and profile on all our guests are available on our website at https://www.dementiaresearcher.nihr.ac.uk.

If you prefer to watch rather than listen, you will find a video version of this podcast on Apple Podcasts, YouTube, and on our website.

Leave us a tip:

Follow us on social media:

Download and Register with our Community App:

The views and opinions expressed by guests in this podcast are their own and do not necessarily reflect those of the producers, funders, or sponsors.

Subscribe to our sister show 'Dementia Researcher The Blogs':

https://podfollow.com/dementia-researcher-blogs

ISTAART Relay Podcast - Neuroimaging PIA

Wed, 12 Jul 2023 00:00:00 +0100

EP3 – Beth Eyre interviews Dr David Cash representing the Neuroimaging PIA. Beth Eyre is a PhD Student (although she recently submitted her thesis and will be defending very soon) at The University of Sheffield. Beth is investigating cognitive and neurovascular function in pre-clinical models of Alzheimer’s disease and in a mixed model of Alzheimer’s and atherosclerosis. Beth is representing the ISTAART Vascular Cognitive Disorders PIA.

There are currently 29 PIAs covering a wide range of interests and fields, from the PIA to Elevate Early Career Researchers to Biofluid Based Biomarkers and everything in between.

To sign-up to ISTAART and a PIA visit:

Note: ISTAART Membership is free for students worldwide, and for researchers of all levels based in Low- and Middle-Income Countries.

A transcript of this show, links and show notes and profile on all our guests are available on our website at https://www.dementiaresearcher.nihr.ac.uk.

If you prefer to watch rather than listen, you will find a video version of this podcast on Apple Podcasts, YouTube, and on our website.

Leave us a tip:

Follow us on social media:

Download and Register with our Community App:

The views and opinions expressed by guests in this podcast are their own and do not necessarily reflect those of the producers, funders, or sponsors.

Subscribe to our sister show 'Dementia Researcher The Blogs':

https://podfollow.com/dementia-researcher-blogs

ISTAART Relay Podcast - Vascular Cognitive Disorders PIA

Tue, 11 Jul 2023 00:00:00 +0100

EP2 – Dr Maura Malpetti interviews Beth Eyre, representing the Vascular Cognitive Disorders PIA. Maura Malpetti is a Race Against Dementia Fellow at University of Cambridge. Maura focusses on multimodal imaging techniques (multi-tracer PET and MRI) integrated with fluid markers, post-mortem validation, and prognostic modelling approaches in frontotemporal lobar degeneration. Maura is representing the ISTAART Frontotemporal Dementia PIA.

Beth Eyre is a PhD Student (although she recently submitted her thesis and will be defending very soon) at The University of Sheffield. Beth is investigating cognitive and neurovascular function in pre-clinical models of Alzheimer’s disease and in a mixed model of Alzheimer’s and atherosclerosis. Beth is representing the ISTAART Vascular Cognitive Disorders PIA.

There are currently 29 PIAs covering a wide range of interests and fields, from the PIA to Elevate Early Career Researchers to Biofluid Based Biomarkers and everything in between.

To sign-up to ISTAART and a PIA visit:

Note: ISTAART Membership is free for students worldwide, and for researchers of all levels based in Low- and Middle-Income Countries.

A transcript of this show, links and show notes and profile on all our guests are available on our website at https://www.dementiaresearcher.nihr.ac.uk.

If you prefer to watch rather than listen, you will find a video version of this podcast on Apple Podcasts, YouTube, and on our website.

Leave us a tip:

Follow us on social media:

Download and Register with our Community App:

The views and opinions expressed by guests in this podcast are their own and do not necessarily reflect those of the producers, funders, or sponsors.

Subscribe to our sister show 'Dementia Researcher The Blogs':

https://podfollow.com/dementia-researcher-blogs

ISTAART Relay Podcast - Frontotemporal Dementia PIA

Mon, 10 Jul 2023 00:00:00 +0100

EP1 – Dr Imre Lengyel interviews Dr Maura Malpetti, representing the Frontotemporal Dementia PIA. Imre Lengyel is a Reader (Associate professor) at Queen’s University Belfast. Imre is researching how we could use the eye as a less expensive, better tolerated, and faster marker to monitor the progression of neurodegeneration. He undertakes clinical eye imaging and use postmortem tissues to generate molecular and high-resolution anatomical confirmation for the changes we see in eye images. Imre is representing the ISTAART The Eye as a Biomarker for AD PIA.

Maura Malpetti is a Race Against Dementia Fellow at University of Cambridge. Maura focusses on multimodal imaging techniques (multi-tracer PET and MRI) integrated with fluid markers, post-mortem validation, and prognostic modelling approaches in frontotemporal lobar degeneration. Maura is representing the ISTAART Frontotemporal Dementia PIA.

There are currently 29 PIAs covering a wide range of interests and fields, from the PIA to Elevate Early Career Researchers to Biofluid Based Biomarkers and everything in between.

To sign-up to ISTAART and a PIA visit:

Note: ISTAART Membership is free for students worldwide, and for researchers of all levels based in Low- and Middle-Income Countries.

A transcript of this show, links and show notes and profile on all our guests are available on our website at https://www.dementiaresearcher.nihr.ac.uk.

If you prefer to watch rather than listen, you will find a video version of this podcast on Apple Podcasts, YouTube, and on our website.

Leave us a tip:

Follow us on social media:

Download and Register with our Community App:

The views and opinions expressed by guests in this podcast are their own and do not necessarily reflect those of the producers, funders, or sponsors.

Subscribe to our sister show 'Dementia Researcher The Blogs':

https://podfollow.com/dementia-researcher-blogs

ISTAART Relay Podcast - Biofluid Based Biomarkers PIA

Fri, 29 Jul 2022 00:00:00 +0100

The Dementia Researcher, ISTAART Relay Podcast is back for a third, 5-part series. Where the interviewee becomes the interviewer. With five leading researchers discussing their research, their field, and the work of the Alzheimer’s Association ISTAART Professional Interest Area they represent.

Part Five – Erica Dove interviews Professor Charlotte Teunissen, representing the Biofluid Based Biomarkers PIA.

Erica Dove is a third year PhD Student, studying at University of Toronto. Her research aims to co-develop an exercise video game designed to reduce falls risk among people with dementia. Inspired to work in dementia through personal experience, when not at work, she can be found obsessing over floral patterns (Yes really). Erica is representing the ISTAART Technology and Dementia PIA.

Charlotte Teunissen is a Professor in Neurochemistry at Amsterdam UMC. Charlotte explores Biomarkers in body fluids, such as cerebrospinal fluid and blood, to understand the disease and improve care for neurological diseases, especially dementias and Multiple Sclerosis. She is representing the ISTAART Biofluid Based Biomarkers PIA.

There are currently 29 PIAs covering a wide range of interests and fields, from the PIA to Elevate Early Career Researchers to Biofluid Based Biomarkers and everything in between.

To sign-up to ISTAART (free for students worldwide, and for people of all grades in Low and Middle Income Countries) and a PIA visit www.alz.org/istaart/

To book your place at this years AAIC Confernence visit – https://aaic.alz.org/

A transcript of this show, links and show notes and profile on all our guests are available on our website at https://www.dementiaresearcher.nihr.ac.uk.

If you prefer to watch rather than listen, you will find a video version of this podcast on Apple Podcasts, YouTube, and on our website.

Leave us a tip:

Follow us on social media:

Download and Register with our Community App:

The views and opinions expressed by guests in this podcast are their own and do not necessarily reflect those of the producers, funders, or sponsors.

Subscribe to our sister show 'Dementia Researcher The Blogs':

https://podfollow.com/dementia-researcher-blogs

ISTAART Relay Podcast - Technology and Dementia PIA

Thu, 28 Jul 2022 00:00:00 +0100

Part Four – Dr Louise Ince interviews Erica Dove representing the Technology and Dementia PIA.

Dr Louise Ince is a Postdoctoral Research Associate at the University of Texas at Austin. Louise’s work focuses on circadian (daily, ~24 h) rhythms in immune function: why our body’s inflammatory response varies depending upon the time-of-day. She is particularly interested in how the dynamics of neuroimmune responses change with aging and in dementia (she is also an expert in pyrotechnics, and hails from Blackpool in the north of England). Louise is representing the ISTAART Immunity and Neurodegeneration PIA.

There are currently 29 PIAs covering a wide range of interests and fields, from the PIA to Elevate Early Career Researchers to Biofluid Based Biomarkers and everything in between.

To sign-up to ISTAART (free for students worldwide, and for people of all grades in Low and Middle Income Countries) and a PIA visit www.alz.org/istaart/

To book your place at this years AAIC Confernence visit – https://aaic.alz.org/

A transcript of this show, links and show notes and profile on all our guests are available on our website at https://www.dementiaresearcher.nihr.ac.uk.

If you prefer to watch rather than listen, you will find a video version of this podcast on Apple Podcasts, YouTube, and on our website.

Leave us a tip:

Follow us on social media:

Download and Register with our Community App:

The views and opinions expressed by guests in this podcast are their own and do not necessarily reflect those of the producers, funders, or sponsors.

Subscribe to our sister show 'Dementia Researcher The Blogs':

https://podfollow.com/dementia-researcher-blogs

ISTAART Relay Podcast - Immunity and Neurodegeneration PIA

Wed, 27 Jul 2022 00:00:00 +0100

Part Three – Dr Hamid Sohrabi, interviews Dr Louise Ince representing the Immunity and Neurodegeneration PIA

Dr Hamid Sohrabi is Director of the Centre for Healthy Ageing – Associate Professor of Psychology and Clinical Neurosciences at Murdoch University, Australia. His research is focussed on screening and clinical diagnostic measures as well as identifying dementia risk factors and resilience and resisting factors including cognitive reserve. Outside work he loves DIY (but never ask him to fit a gate in your garden). Hamid is representing the ISTAART Reserve, Resilience and Protective Factors PIA.

There are currently 29 PIAs covering a wide range of interests and fields, from the PIA to Elevate Early Career Researchers to Biofluid Based Biomarkers and everything in between.

To sign-up to ISTAART (free for students worldwide, and for people of all grades in Low and Middle Income Countries) and a PIA visit www.alz.org/istaart/

To book your place at this years AAIC Confernence visit – https://aaic.alz.org/

A transcript of this show, links and show notes and profile on all our guests are available on our website at https://www.dementiaresearcher.nihr.ac.uk.

If you prefer to watch rather than listen, you will find a video version of this podcast on Apple Podcasts, YouTube, and on our website.

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The views and opinions expressed by guests in this podcast are their own and do not necessarily reflect those of the producers, funders, or sponsors.

Subscribe to our sister show 'Dementia Researcher The Blogs':

https://podfollow.com/dementia-researcher-blogs

ISTAART Relay Podcast - Reserve, Resilience and Protective Factors PIA

Tue, 26 Jul 2022 00:00:00 +0100

Part Two – Dr Rik Ossenkoppele, interviews Dr Hamid Sohrabi representing the Resilience and Protective Factors PIA

Dr Rik Ossenkoppele is an Associate Professor of Translational Neuroscience at Amsterdam UMC and Lund University. His area of research is Alzheimer’s disease and other neurodegenerative disorders, brain imaging, biomarkers, cognition. Rik also happens to be a qualifiied PE Teacher, and he is representing the ISTAART Atypical Alzheimer’s Disease PIA.

There are currently 29 PIAs covering a wide range of interests and fields, from the PIA to Elevate Early Career Researchers to Biofluid Based Biomarkers and everything in between.

To sign-up to ISTAART (free for students worldwide, and for people of all grades in Low and Middle Income Countries) and a PIA visit www.alz.org/istaart/

To book your place at this years AAIC Confernence visit – https://aaic.alz.org/

A transcript of this show, links and show notes and profile on all our guests are available on our website at https://www.dementiaresearcher.nihr.ac.uk.

If you prefer to watch rather than listen, you will find a video version of this podcast on Apple Podcasts, YouTube, and on our website.

Leave us a tip:

Follow us on social media:

Download and Register with our Community App:

The views and opinions expressed by guests in this podcast are their own and do not necessarily reflect those of the producers, funders, or sponsors.

Subscribe to our sister show 'Dementia Researcher The Blogs':

https://podfollow.com/dementia-researcher-blogs

ISTAART Relay Podcast - Atypical Alzheimer's Disease PIA

Mon, 25 Jul 2022 00:00:00 +0100

Part One – Professor Charlotte Teunissen, interviews Dr Rik Ossenkoppele representing the Atypical Alzheimer’s Disease PIA

There are currently 29 PIAs covering a wide range of interests and fields, from the PIA to Elevate Early Career Researchers to Biofluid Based Biomarkers and everything in between.

To sign-up to ISTAART (free for students worldwide, and for people of all grades in Low and Middle Income Countries) and a PIA visit www.alz.org/istaart/

To book your place at this years AAIC Confernence visit – https://aaic.alz.org/

A transcript of this show, links and show notes and profile on all our guests are available on our website at https://www.dementiaresearcher.nihr.ac.uk.

If you prefer to watch rather than listen, you will find a video version of this podcast on Apple Podcasts, YouTube, and on our website.

Leave us a tip:

Follow us on social media:

Download and Register with our Community App:

The views and opinions expressed by guests in this podcast are their own and do not necessarily reflect those of the producers, funders, or sponsors.

Subscribe to our sister show 'Dementia Researcher The Blogs':

https://podfollow.com/dementia-researcher-blogs

ISTAART Relay Podcast - Lewy body dementia PIA

Fri, 23 Jul 2021 00:00:00 +0100

The Dementia Researcher, ISTAART PIA Relay Podcast is back for a second, 5-part series. Where the interviewee becomes the interviewer. With five leading researchers discussing their research, their field, and the work of the Alzheimer’s Association ISTAART Professional Interest Area they represent. Part Five – Dr Claudio Babiloni interviews Dr Joe Kane Dr Claudio Babiloni is an Associate Professor of Physiology at Sapienza University of Rome. Claudio is investigating the brain rhythms underlying the regulation of vigilance and cognitive functions in aging, with a particular interest in the main progressive neurodegenerative diseases leading to dementia such as Alzheimer's, Lewy body, and Parkinson's diseases. The primary methods of this research are EEG and neuroimaging techniques. Claudio is representing the Electrophysiology PIA. Dr Joe Kane is a Clinical Academic Lecturer working at Queen’s University Belfast. Joe splits his time between research and clinical work as an old age psychiatrist. Having got his taste for academia during his PhD studies working in of Lewy body dementia on the DIAMOND-Lewy programme of studies. Joe is representing the Lewy body dementia PIA. You can find out more about our panellists, and their work on our website: https://www.dementiaresearcher.nihr.ac.uk A transcript of this podcast is also available here https://www.dementiaresearcher.nihr.ac.uk/podcast-relay-one-season-2 ___________________________ The Alzheimer's Association International Society to Advance Alzheimer's Research and Treatment (ISTAART) convenes the global Alzheimer's and dementia science community. Members share knowledge, fuel collaboration and advance research to find more effective ways to detect, treat and prevent Alzheimer's and other dementias. Professional Interest Areas (PIA) are an assembly of ISTAART members with common subspecialties or interests. There are currently 27 PIA covering a wide range of interests and fields, from the PIA to Elevate Early Career Researchers to Biofluid Based Biomarkers and everything in between. To sign-up to ISTAART and a PIA visit www.alz.org/istaart/ _________________________ Finally, please review, like, and share our podcast - and don't forget to subscribe to ensure you never miss an episode. Register on our website to receive your weekly bulletin, and to access more great content – blogs, science, career support + much more. This podcast is brought to you in association with Alzheimer's Research UK and Alzheimer's Society, who we thank for their ongoing support. Finally, the views and opinions expressed by guests in this podcast represent those of the guests and do not necessarily reflect those of NIHR Dementia Researchers, PIA membership, ISTAART or the Alzheimer's Association.

ISTAART Relay Podcast - Electrophysiology PIA

Thu, 22 Jul 2021 00:00:00 +0100

The Dementia Researcher, ISTAART PIA Relay Podcast is back for a second, 5-part series. Where the interviewee becomes the interviewer. With five leading researchers discussing their research, their field, and the work of the Alzheimer’s Association ISTAART Professional Interest Area they represent. Part Four – Dr Betty Tijms interviews Dr Claudio Babiloni Dr Betty Tijms is an Associate Professor at the Alzheimer center, department of Neurology, Amsterdam UMC in the Netherlands. Jennifer’s research focusses on better understanding interindividual differences in the early stages of Alzheimer’s disease that are related to developing dementia, through MR imaging and CSF proteomic analyses. She has recently, started work on cerebrospinal fluid proteomics as one of the most comprehensive measures to get more insight into interindividual differences in underlying pathophysiological processes. Betty is representing the Neuroimaging PIA. Dr Claudio Babiloni is an Associate Professor of Physiology at Sapienza University of Rome. Claudio is investigating the brain rhythms underlying the regulation of vigilance and cognitive functions in aging, with a particular interest in the main progressive neurodegenerative diseases leading to dementia such as Alzheimer's, Lewy body, and Parkinson's diseases. The primary methods of this research are EEG and neuroimaging techniques. Claudio is representing the Electrophysiology PIA. You can find out more about our panellists, and their work on our website: https://www.dementiaresearcher.nihr.ac.uk A transcript of this podcast is also available here https://www.dementiaresearcher.nihr.ac.uk/podcast-relay-one-season-2 ___________________________ The Alzheimer's Association International Society to Advance Alzheimer's Research and Treatment (ISTAART) convenes the global Alzheimer's and dementia science community. Members share knowledge, fuel collaboration and advance research to find more effective ways to detect, treat and prevent Alzheimer's and other dementias. Professional Interest Areas (PIA) are an assembly of ISTAART members with common subspecialties or interests. There are currently 27 PIA covering a wide range of interests and fields, from the PIA to Elevate Early Career Researchers to Biofluid Based Biomarkers and everything in between. To sign-up to ISTAART and a PIA visit www.alz.org/istaart/ _________________________ Finally, please review, like, and share our podcast - and don't forget to subscribe to ensure you never miss an episode. Register on our website to receive your weekly bulletin, and to access more great content – blogs, science, career support + much more. This podcast is brought to you in association with Alzheimer's Research UK and Alzheimer's Society, who we thank for their ongoing support. Finally, the views and opinions expressed by guests in this podcast represent those of the guests and do not necessarily reflect those of NIHR Dementia Researchers, PIA membership, ISTAART or the Alzheimer's Association.

ISTAART Relay Podcast - Neuroimaging PIA

Wed, 21 Jul 2021 00:00:00 +0100

The Dementia Researcher, ISTAART PIA Relay Podcast is back for a second, 5-part series. Where the interviewee becomes the interviewer. With five leading researchers discussing their research, their field, and the work of the Alzheimer’s Association ISTAART Professional Interest Area they represent. Part Three – Professor Jennifer Whitwell interviews Dr Betty Tijms Jennifer Whitwell is a Professor of Radiology at the May Clinic, Rochester having originally grown up and trained in the UK. Jennifer’s research focuses on the investigation of neuroimaging biomarkers, including MRI and PET, in different neurodegenerative disorders, including Alzheimer’s disease and frontotemporal lobar degeneration. She is particularly focused on using neuroimaging to better understand disease mechanisms and progression in patients with atypical clinical presentations of Alzheimer’s disease, highlighting the phenotypic heterogeneity present in this disease. Jennifer is representing the Atypical Alzheimer’s Disease PIA. Dr Betty Tijms is an Associate Professor at the Alzheimer center, department of Neurology, Amsterdam UMC in the Netherlands. Jennifer’s research focusses on better understanding interindividual differences in the early stages of Alzheimer’s disease that are related to developing dementia, through MR imaging and CSF proteomic analyses. She has recently, started work on cerebrospinal fluid proteomics as one of the most comprehensive measures to get more insight into interindividual differences in underlying pathophysiological processes. Betty is representing the Neuroimaging PIA. You can find out more about our panellists, and their work on our website: https://www.dementiaresearcher.nihr.ac.uk A transcript of this podcast is also available here https://www.dementiaresearcher.nihr.ac.uk/podcast-relay-one-season-2 ___________________________ Like what you hear? Then we have a favour to ask... Dementia Researcher is nominated in the 2021 Peoples Choice Podcast Awards - to get through round one, we need your votes - please head over to https://www.podcastawards.com/app/signup - complete the short registration form, and then select Dementia Researcher in the Medicine & Science and Peoples Choice categories (don't worry, you don't have to do any of the others) - hit submit, and verify - JOB DONE Winning this award would be a great way to thank and recognise the contribution of all our hosts and guests who give up their time freely, to share their science and career tips, and to support ECRs to succeed and to raise the profile of Dementia Research. _________________________ Finally, please review, like, and share our podcast - and don't forget to subscribe to ensure you never miss an episode. Register on our website to receive your weekly bulletin, and to access more great content – blogs, science, career support + much more This podcast is brought to you in association with Alzheimer's Research UK and Alzheimer's Society, who we thank for their ongoing support. Finally, the views and opinions expressed by guests in this podcast represent those of the guests and do not necessarily reflect those of NIHR Dementia Researchers, PIA membership, ISTAART or the Alzheimer's Association.

ISTAART Relay Podcast - Neuropsychiatric Syndromes PIA

Mon, 19 Jul 2021 00:00:00 +0100

The Dementia Researcher, ISTAART PIA Relay Podcast is back for a second, 5-part series. Where the interviewee becomes the interviewer. With five leading researchers discussing their research, their field, and the work of the Alzheimer’s Association ISTAART Professional Interest Area they represent. Part One – Dr Joe Kane interviews Professor Zahinoor Ismail Dr Joe Kane is a Clinical Academic Lecturer working at Queen’s University Belfast. Joe splits his time between research and clinical work as an old age psychiatrist. Having got his taste for academia during his PhD studies working in of Lewy body dementia on the DIAMOND-Lewy programme of studies. Joe is representing the Lewy body dementia PIA. Professor Zahinoor Ismail is a Neuropsychiatrist; Professor of Psychiatry, Neurology, Epidemiology, and Pathology at the Hotchkiss Brain Institute and O’Brien Institute for Public Health; Cumming School of Medicine; University of Calgary. Zahinoor works on Dementia prognostication and early dementia detection using non-cognitive markers, treatment of neuropsychiatric syndromes across the cognitive spectrum, pharmacoepidemiology. Zahinoor is representing the Neuropsychiatric Syndromes PIA. You can find out more about our panellists, and their work on our website: https://www.dementiaresearcher.nihr.ac.uk A transcript of this podcast is also available here https://www.dementiaresearcher.nihr.ac.uk/podcast-relay-one-season-2 ___________________________ The Alzheimer's Association International Society to Advance Alzheimer's Research and Treatment (ISTAART) convenes the global Alzheimer's and dementia science community. Members share knowledge, fuel collaboration and advance research to find more effective ways to detect, treat and prevent Alzheimer's and other dementias. Professional Interest Areas (PIA) are an assembly of ISTAART members with common subspecialties or interests. There are currently 27 PIA covering a wide range of interests and fields, from the PIA to Elevate Early Career Researchers to Biofluid Based Biomarkers and everything in between. To sign-up to ISTAART and a PIA visit www.alz.org/istaart/ _________________________ Like what you hear? Then we have a favour to ask... Dementia Researcher is nominated in the 2021 Peoples Choice Podcast Awards - to get through round one, we need your votes - please head over to https://www.podcastawards.com/app/signup - complete the short registration form, and then select Dementia Researcher in the Medicine & Science and Peoples Choice categories (don't worry, you don't have to do any of the others) - hit submit, and verify - JOB DONE Winning this award would be a great way to thank and recognise the contribution of all our hosts and guests who give up their time freely, to share their science and career tips, and to support ECRs to succeed and to raise the profile of Dementia Research. _________________________ Finally, please review, like, and share our podcast - and don't forget to subscribe to ensure you never miss an episode. Register on our website to receive your weekly bulletin, and to access more great content – blogs, science, career support + much more This podcast is brought to you in association with Alzheimer's Research UK and Alzheimer's Society, who we thank for their ongoing support. Finally, the views and opinions expressed by guests in this podcast represent those of the guests and do not necessarily reflect those of NIHR Dementia Researchers, PIA membership, ISTAART or the Alzheimer's Association.

ISTAART Relay Podcast - Perioperative Cognition and Delirium PIA

Fri, 24 Jul 2020 00:00:00 +0100

A five-part special relay podcast series, where the interviewee becomes the interviewer. With five leading researchers discussing their research, their field, and the work of the Alzheimer’s Association ISTAART Professional Interest Area they represent. Part Five - Dr Sietske Sikkes interviews Professor David Scott Dr Sietske Sikkes is a Clinical Neuropsychologist and Epidemiologist and Assistant professor at the Alzheimer Centre Amsterdam at Amsterdam University Medical Centre & VU University, Netherlands. Sietske’s is researching Neuropsychology, cognition, instrument development, psychometrics and non-pharmacological interventions. She is representing the Non-pharmacological Interventions PIA and Subjective Cognitive Decline PIA. David Scott is Director of the Department of Anaesthesia and Acute Pain Medicine, St. Vincent’s Hospital Melbourne and Professor, School of Medicine, University of Melbourne, Australia. David is researches Perioperative Neurocognitive Disorders – in particular, delirium and cognitive decline associated with anaesthesia and surgery. He is representing the Perioperative Cognition and Delirium PIA. ______________________________________________ This podcast series is brought to you by Dementia Researcher. You can find out more about our panellists, and their work on our website www.dementiaresearcher.nihr.ac.uk. A transcript of this podcast is also available here https://www.dementiaresearcher.nihr.ac.uk/podcasts ______________________________________________ The Alzheimer's Association International Society to Advance Alzheimer's Research and Treatment (ISTAART) convenes the global Alzheimer's and dementia science community. Members share knowledge, fuel collaboration and advance research to find more effective ways to detect, treat and prevent Alzheimer's and other dementias. Professional Interest Areas (PIA) are an assembly of ISTAART members with common subspecialties or interests. There are currently 25 PIA covering a wide range of interests and fields, from the Alliance of Women Alzheimer's Researchers (AWARE) PIA to Biofluid Based Biomarkers and everything in between. To sign-up to ISTAART and a PIA visit www.alz.org/istaart/ ______________________________________________ Throughout July 2020, Dementia Researcher is giving you a chance to win a pair of Beats Studio Headphones. To be in with a chance to win, complete three east steps: 1. Leave us a review on iTunes 2. Register and attend one of our webinars 3. Register on our website. Winner will be chosen at random on the 1st August, and announced via Twitter follow-us @Dem_Researcher For more information visit www.dementiaresearcher.nihr.ac.uk ______________________________________________ Finally, the views and opinions expressed by guests in this podcast represent those of the guests and do not necessarily reflect those of NIHR Dementia Researchers, PIA membership, ISTAART or the Alzheimer's Association.

ISTAART Relay Podcast - Subjective Cognitive Decline PIA

Thu, 23 Jul 2020 00:00:00 +0100

A five-part special relay podcast series, where the interviewee becomes the interviewer. With five leading researchers discussing their research, their field, and the work of the Alzheimer’s Association ISTAART Professional Interest Area they represent. Part Four - Dr Cécilia Samieri interviews Dr Sietske Sikkes Dr Cécilia Samieri is an Epidemiologist and Senior researcher at INSERM (French National Institute for Health), in Bordeaux, France. Cécilia’s research looks at Nutritional epidemiology, lifestyle risk factors, exposome. She is representing the Nutrition and Metabolic Disorders PIA. Dr Sietske Sikkes is a Clinical Neuropsychologist and Epidemiologist and Assistant professor at the Alzheimer Centre Amsterdam at Amsterdam University Medical Centre & VU University, Netherlands. Sietske’s is researching Neuropsychology, cognition, instrument development, psychometrics and non-pharmacological interventions. She is representing the Non-pharmacological Interventions PIA and Subjective Cognitive Decline PIA. ______________________________________________ This podcast series is brought to you by Dementia Researcher. You can find out more about our panellists, and their work on our website www.dementiaresearcher.nihr.ac.uk. A transcript of this podcast is also available here https://www.dementiaresearcher.nihr.ac.uk/podcasts ______________________________________________ The Alzheimer's Association International Society to Advance Alzheimer's Research and Treatment (ISTAART) convenes the global Alzheimer's and dementia science community. Members share knowledge, fuel collaboration and advance research to find more effective ways to detect, treat and prevent Alzheimer's and other dementias. Professional Interest Areas (PIA) are an assembly of ISTAART members with common subspecialties or interests. There are currently 25 PIA covering a wide range of interests and fields, from the Alliance of Women Alzheimer's Researchers (AWARE) PIA to Biofluid Based Biomarkers and everything in between. To sign-up to ISTAART and a PIA visit www.alz.org/istaart/ ______________________________________________ Throughout July 2020, Dementia Researcher is giving you a chance to win a pair of Beats Studio Headphones. To be in with a chance to win, complete three east steps: 1. Leave us a review on iTunes 2. Register and attend one of our webinars 3. Register on our website. Winner will be chosen at random on the 1st August, and announced via Twitter follow-us @Dem_Researcher For more information visit www.dementiaresearcher.nihr.ac.uk ______________________________________________ Finally, the views and opinions expressed by guests in this podcast represent those of the guests and do not necessarily reflect those of NIHR Dementia Researchers, PIA membership, ISTAART or the Alzheimer's Association.

ISTAART Relay Podcast - Nutrition and Metabolic Disorders PIA

Wed, 22 Jul 2020 00:00:00 +0100

A five-part special relay podcast series, where the interviewee becomes the interviewer. With five leading researchers discussing their research, their field, and the work of the Alzheimer’s Association ISTAART Professional Interest Area they represent. Part Three - Dr Prashanthi Vemuri interviews Dr Cécilia Samieri Dr Prashanthi Vemuri is Associate Professor of Radiology at The Mayo Clinic College of Medicine and Science, Rochester, USA. Prashanthi’s research is focused on imaging biomarkers of Neurodegenerative and Cerebrovascular Disease. She is representing the Reserve, Resilience, and Protective Factors PIA. Dr Cécilia Samieri is an Epidemiologist and Senior researcher at INSERM (French National Institute for Health), in Bordeaux, France. Cécilia’s research looks at Nutritional epidemiology, lifestyle risk factors, exposome. She is representing the Nutrition and Metabolic Disorders PIA. ______________________________________________ This podcast series is brought to you by Dementia Researcher. You can find out more about our panellists, and their work on our website www.dementiaresearcher.nihr.ac.uk. A transcript of this podcast is also available here https://www.dementiaresearcher.nihr.ac.uk/podcasts ______________________________________________ The Alzheimer's Association International Society to Advance Alzheimer's Research and Treatment (ISTAART) convenes the global Alzheimer's and dementia science community. Members share knowledge, fuel collaboration and advance research to find more effective ways to detect, treat and prevent Alzheimer's and other dementias. Professional Interest Areas (PIA) are an assembly of ISTAART members with common subspecialties or interests. There are currently 25 PIA covering a wide range of interests and fields, from the Alliance of Women Alzheimer's Researchers (AWARE) PIA to Biofluid Based Biomarkers and everything in between. To sign-up to ISTAART and a PIA visit www.alz.org/istaart/ ______________________________________________ Throughout July 2020, Dementia Researcher is giving you a chance to win a pair of Beats Studio Headphones. To be in with a chance to win, complete three east steps: 1. Leave us a review on iTunes 2. Register and attend one of our webinars 3. Register on our website. Winner will be chosen at random on the 1st August, and announced via Twitter follow-us @Dem_Researcher For more information visit www.dementiaresearcher.nihr.ac.uk ______________________________________________ Finally, the views and opinions expressed by guests in this podcast represent those of the guests and do not necessarily reflect those of NIHR Dementia Researchers, PIA membership, ISTAART or the Alzheimer's Association.

ISTAART Relay Podcast - Reserve, Resilience, and Protective Factors PIA

Tue, 21 Jul 2020 00:00:00 +0100

A five-part special relay podcast series, where the interviewee becomes the interviewer. With five leading researchers discussing their research, their field, and the work of the Alzheimer’s Association ISTAART Professional Interest Area they represent. Part Two - Professor Henrik Zetterberg interviews Dr Prashanthi Vemuri Henrik Zetterberg is Professor of Neurochemistry, Senior Consultant in Clinical Chemistry and Head of Department at The Sahlgrenska Academy within the University of Gothenburg, Sweden, and University College London, UK. Henrik’s work is focused on Fluid biomarkers for neurodegenerative dementias. He is representing the Biofluid-based biomarkers PIA. Dr Prashanthi Vemuri is Associate Professor of Radiology at The Mayo Clinic College of Medicine and Science, Rochester, USA. Prashanthi’s research is focused on imaging biomarkers of Neurodegenerative and Cerebrovascular Disease. She is representing the Reserve, Resilience, and Protective Factors PIA. ______________________________________________ This podcast series is brought to you by Dementia Researcher. You can find out more about our panellists, and their work on our website www.dementiaresearcher.nihr.ac.uk. A transcript of this podcast is also available here https://www.dementiaresearcher.nihr.ac.uk/podcasts ______________________________________________ The Alzheimer's Association International Society to Advance Alzheimer's Research and Treatment (ISTAART) convenes the global Alzheimer's and dementia science community. Members share knowledge, fuel collaboration and advance research to find more effective ways to detect, treat and prevent Alzheimer's and other dementias. Professional Interest Areas (PIA) are an assembly of ISTAART members with common subspecialties or interests. There are currently 25 PIA covering a wide range of interests and fields, from the Alliance of Women Alzheimer's Researchers (AWARE) PIA to Biofluid Based Biomarkers and everything in between. To sign-up to ISTAART and a PIA visit www.alz.org/istaart/ ______________________________________________ Throughout July 2020, Dementia Researcher is giving you a chance to win a pair of Beats Studio Headphones. To be in with a chance to win, complete three east steps: 1. Leave us a review on iTunes 2. Register and attend one of our webinars 3. Register on our website. Winner will be chosen at random on the 1st August, and announced via Twitter follow-us @Dem_Researcher For more information visit www.dementiaresearcher.nihr.ac.uk ______________________________________________ Finally, the views and opinions expressed by guests in this podcast represent those of the guests and do not necessarily reflect those of NIHR Dementia Researchers, PIA membership, ISTAART or the Alzheimer's Association.

ISTAART Relay Podcast - Biofluid Based Biomarkers PIA

Mon, 20 Jul 2020 00:00:00 +0100

A five-part special relay podcast series, where the interviewee becomes the interviewer. With five leading researchers discussing their research, their field, and the work of the Alzheimer’s Association ISTAART Professional Interest Area they represent. Part One - Professor David Scott interviews Professor Henrik Zetterberg David Scott is Director of the Department of Anaesthesia and Acute Pain Medicine, St. Vincent’s Hospital Melbourne and Professor, School of Medicine, University of Melbourne, Australia. David is researches Perioperative Neurocognitive Disorders – in particular, delirium and cognitive decline associated with anaesthesia and surgery. He is representing the Perioperative Cognition and Delirium PIA. Henrik Zetterberg is Professor of Neurochemistry, Senior Consultant in Clinical Chemistry and Head of Department at The Sahlgrenska Academy within the University of Gothenburg, Sweden, and University College London, UK. Henrik’s work is focused on Fluid biomarkers for neurodegenerative dementias. He is representing the Biofluid Based Biomarkers PIA. ______________________________________________ This podcast series is brought to you by Dementia Researcher. You can find out more about our panellists, and their work on our website www.dementiaresearcher.nihr.ac.uk. A transcript of this podcast is also available here https://www.dementiaresearcher.nihr.ac.uk/podcasts ______________________________________________ The Alzheimer's Association International Society to Advance Alzheimer's Research and Treatment (ISTAART) convenes the global Alzheimer's and dementia science community. Members share knowledge, fuel collaboration and advance research to find more effective ways to detect, treat and prevent Alzheimer's and other dementias. Professional Interest Areas (PIA) are an assembly of ISTAART members with common subspecialties or interests. There are currently 25 PIA covering a wide range of interests and fields, from the Alliance of Women Alzheimer's Researchers (AWARE) PIA to Biofluid Based Biomarkers and everything in between. To sign-up to ISTAART and a PIA visit www.alz.org/istaart/ ______________________________________________ Throughout July 2020, Dementia Researcher is giving you a chance to win a pair of Beats Studio Headphones. To be in with a chance to win, complete three east steps: 1. Leave us a review on iTunes 2. Register and attend one of our webinars 3. Register on our website. Winner will be chosen at random on the 1st August, and announced via Twitter follow-us @Dem_Researcher For more information visit www.dementiaresearcher.nihr.ac.uk ______________________________________________ Finally, the views and opinions expressed by guests in this podcast represent those of the guests and do not necessarily reflect those of NIHR Dementia Researchers, PIA membership, ISTAART or the Alzheimer's Association.

Relay Podcast - Technology and Dementia PIA

Mon, 29 Jun 2026 08:00:00 +0100

Welcome to the seventh season of the Dementia Researcher X ISTAART PIA Relay Podcast. Across six episodes, leading early career and senior researchers hand the mic from one ISTAART PIA to the next, giving you an honest, peer-to-peer tour of where dementia research is actually heading, from wearables and biomarkers to policy and trial design, in the run-up to AAIC.

Sleep might be one of the earliest windows we have into brain health, and Dr Vanessa Young thinks the way we measure it is about to change. Fresh from finishing her PhD in May, Vanessa is a postdoc at the Glenn Biggs Institute and Communications Chair of the Technology and Dementia PIA. She studies sleep and the ageing brain, where the relationship seems to run both ways: as dementia develops, sleep gets worse, and poor sleep may feed back into the disease. With host Dr Carla Abdelnour, she gets into digital biomarkers, why wearables let you capture sleep continuously at home rather than in a one-off sleep study, and the move from wearables to "nearables", bed sensors and room radar that ask nothing of the participant at all. They also cover the analysis headache that comes with years of continuous data, the equity problem when a study needs home Wi-Fi, and what the PIA has planned for its full-day AAIC preconference on AI.

Takeaways

Sleep and dementia feed each other, so sleep is worth studying as somewhere we might actually step in and help.
Wearables capture sleep night after night at home, which reaches people who live nowhere near a big sleep centre.
The field is shifting from wearables to "nearables", sensors in the mattress or radar in the room, to cut participant burden and bias.
Years of continuous data brings its own problem: telling meaningful signal apart from background noise.
If a study needs Wi-Fi to send its data, it quietly excludes people, so digital equity has to be designed in.

There are currently 30 PIAs covering a wide range of interests and fields, from Neuroimaging to Diversity and Disparities and everything in between.

Find out more at https://istaart.alz.org/

A transcript of this show, links and show notes and profile on all our guests are available on our website at https://www.dementiaresearcher.nihr.ac.uk.

If you prefer to watch rather than listen, you will find a video version of this podcast on Apple Podcasts, YouTube, and on our website.

Leave us a tip:

Follow us on social media:

Download and Register with our Community App:

The views and opinions expressed by guests in this podcast are their own and do not necessarily reflect those of the producers, funders, or sponsors.

Subscribe to our sister show 'Dementia Researcher The Blogs':

https://podfollow.com/dementia-researcher-blogs

Relay Podcast - Health Policy PIA

Tue, 30 Jun 2026 08:00:00 +0100

If we cured Alzheimer's tomorrow but did no work on cost, distribution or access, we would have cured it only for the richest people in the world. That line from Lillian Morgado sits at the centre of this episode. Lillian is a research coordinator at Georgia State University and Communications Chair of the ISTAART Health Policy PIA, working mainly in qualitative research and legal epidemiology. With host Dr Vanessa Young, she talks through what qualitative work actually involves, her research on caregivers and people with dementia in the justice system, and the question that opened up next: what happens to someone with no caregiver to advocate for them. They get into why AI and blood-based biomarkers are as much policy problems as scientific ones, how regulation differs across borders, and why policy is the bridge that decides whether science reaches the people it was meant for. Lillian also runs through the Health Policy PIA's busy week at AAIC, from PIA Day to a featured research session on dementia care across countries.

Takeaways

Policy is the bridge from the lab to the patient; without it, a breakthrough only reaches the few who can already afford care.
Qualitative interviews and coding surface the right questions before the big quantitative money goes in.
Caregivers matter enormously when someone with dementia meets the justice system, which raises the question of those who have none.
AI and blood-based biomarkers carry legal and access questions, and the rules differ between, say, the US and Europe under GDPR.
You do not join a PIA because you already belong; you belong because you get involved, and you need not be an expert to contribute.

There are currently 30 PIAs covering a wide range of interests and fields, from Neuroimaging to Diversity and Disparities and everything in between.

Find out more at https://istaart.alz.org/

A transcript of this show, links and show notes and profile on all our guests are available on our website at https://www.dementiaresearcher.nihr.ac.uk.

If you prefer to watch rather than listen, you will find a video version of this podcast on Apple Podcasts, YouTube, and on our website.

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The views and opinions expressed by guests in this podcast are their own and do not necessarily reflect those of the producers, funders, or sponsors.

Subscribe to our sister show 'Dementia Researcher The Blogs':

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Relay Podcast - Down Syndrome and Alzheimer's Disease PIA

Wed, 01 Jul 2026 08:00:00 +0100

Almost everyone born with Down syndrome overproduces the amyloid precursor protein from birth, which makes it one of the clearest natural windows we have into how Alzheimer's begins. Dr Patrick Lao, Assistant Professor at Columbia and Programmes Chair of the ISTAART Down Syndrome and Alzheimer's Disease PIA, comes from a medical physics background and uses multimodal neuroimaging to map the disease across its genetic and sporadic forms. With host Lillian Morgado, he explains amyloid and tau PET, Thal phases and Braak staging, and how chronological age can stand in for disease stage in this population, with a typical symptom onset around 54. They talk about why people with Down syndrome were long left out of anti-amyloid trials and how that is now changing, and the risk and resilience research asking why some people fall off the expected timeline. Patrick also previews the PIA's AAIC PIA Day session on returning results, plus the separate DSAD/ADAD conference coming to London next year.

Takeaways

Genetic forms of Alzheimer's, including Down syndrome, let researchers study the earliest disease pathways before symptoms appear.
In Down syndrome, chronological age can approximate disease stage, with symptoms typically expected around age 54.
Imaging shows where amyloid and tau sit in the brain, the spatial detail a blood test cannot give.
People with Down syndrome were historically excluded from anti-amyloid trials; that is shifting, with a lecanemab safety extension now underway.
Not everyone follows the population timeline, and risk and resilience work asks what pushes onset earlier or later.

There are currently 30 PIAs covering a wide range of interests and fields, from Neuroimaging to Diversity and Disparities and everything in between.

Find out more at https://istaart.alz.org/

A transcript of this show, links and show notes and profile on all our guests are available on our website at https://www.dementiaresearcher.nihr.ac.uk.

If you prefer to watch rather than listen, you will find a video version of this podcast on Apple Podcasts, YouTube, and on our website.

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The views and opinions expressed by guests in this podcast are their own and do not necessarily reflect those of the producers, funders, or sponsors.

Subscribe to our sister show 'Dementia Researcher The Blogs':

https://podfollow.com/dementia-researcher-blogs

Relay Podcast - Lewy Body Dementias PIA

Thu, 02 Jul 2026 08:00:00 +0100

Lewy body pathology shows up in roughly 30% of the brains of people who had dementia, yet it gets diagnosed in only about 5% of cases. Closing that gap has shaped much of Dr Joe Kane's career. Joe is a geriatric psychiatrist at Queen's University Belfast and outgoing Chair of the ISTAART Lewy Body Dementias PIA, and with host Dr Patrick Lao he traces his work from the Diamond Lewy programme to consensus diagnostic guidelines built by Delphi process. They discuss the symptoms clinicians often miss because they don't think to ask, from constipation to loss of smell, the cardiac scans and seed amplification assays now detecting pathology in CSF and even skin, and the TOP HAT trial repurposing an anti-sickness drug for hallucinations. Joe makes the case for a Lewy body specific rating scale, explains why the prodrome may be psychiatric or delirium rather than cognitive, and runs through the PIA's biggest AAIC programme in years, including a PIA Day panel on seed amplification assays.

Takeaways

Lewy body dementia is heavily underdiagnosed: pathology appears in about 30% of brains but is diagnosed in around 5%.
Much of the disease shows outside the brain, in constipation, blood pressure and smell, so it gets missed if nobody asks.
Seed amplification assays, now usable on CSF and even a small skin biopsy, are changing how the pathology is detected.
Trials can fail on the wrong yardstick, which is why the PIA is building a Lewy body specific rating scale.
The prodrome is not only cognitive; the first sign can be depression, psychosis or delirium, and those gaps need data.

There are currently 30 PIAs covering a wide range of interests and fields, from Neuroimaging to Diversity and Disparities and everything in between.

Find out more at https://istaart.alz.org/

A transcript of this show, links and show notes and profile on all our guests are available on our website at https://www.dementiaresearcher.nihr.ac.uk.

If you prefer to watch rather than listen, you will find a video version of this podcast on Apple Podcasts, YouTube, and on our website.

Leave us a tip:

Follow us on social media:

Download and Register with our Community App:

The views and opinions expressed by guests in this podcast are their own and do not necessarily reflect those of the producers, funders, or sponsors.

Subscribe to our sister show 'Dementia Researcher The Blogs':

https://podfollow.com/dementia-researcher-blogs

Relay Podcast - PIA to Elevate Early Career Researchers

Fri, 03 Jul 2026 08:00:00 +0100

Most people with hypertension after 50 never develop dementia, so what separates those who do? That is the question driving Dr Sindhuja Tirumalai Govindarajan, a neuroimaging researcher and outgoing Chair of the ISTAART PEERs PIA, recorded as she moves from a postdoc at the University of Pennsylvania to an assistant professorship at the Karolinska Institute. With host Dr Joe Kane she explains how machine learning on tens of thousands of MRI scans can pick up subtle brain changes years before symptoms, and why scans from different scanners have to be harmonised first. The conversation then turns to PEERs itself, a PIA built not around one research area but around early career researchers everywhere, and the work of levelling opportunity across borders through local routes like Neuroscience Next, WYLD and INTERDEM Academy. Sindhuja runs through the PIA's AAIC workshops, from narrative CVs to social bingo for ECRs, and closes with practical advice on getting people involved: make the ask specific.

Takeaways

Machine learning on large MRI datasets can detect brain changes years before any cognitive symptoms show.
Scans from different scanners must be harmonised first, stripping out machine noise so only the biology remains.
PEERs exists to level opportunity for early career researchers wherever they are, across every research area.
Local routes such as Neuroscience Next, WYLD and INTERDEM Academy widen access for those who cannot get to the big conference.
Interest among ECRs is common but clarity often is not, so make the ask specific and people will step up.

There are currently 30 PIAs covering a wide range of interests and fields, from Neuroimaging to Diversity and Disparities and everything in between.

Find out more at https://istaart.alz.org/

A transcript of this show, links and show notes and profile on all our guests are available on our website at https://www.dementiaresearcher.nihr.ac.uk.

If you prefer to watch rather than listen, you will find a video version of this podcast on Apple Podcasts, YouTube, and on our website.

Leave us a tip:

Follow us on social media:

Download and Register with our Community App:

The views and opinions expressed by guests in this podcast are their own and do not necessarily reflect those of the producers, funders, or sponsors.

Subscribe to our sister show 'Dementia Researcher The Blogs':

https://podfollow.com/dementia-researcher-blogs

Relay Podcast - Clinical Trials Advancement and Methods PIA 2026

Sat, 04 Jul 2026 08:00:00 +0100

Series closer, and the relay comes full circle: Carla Abdelnour, who hosted episode one, returns as the guest. Carla is a clinician scientist in Barcelona and incoming Chair of the ISTAART Clinical Trials Advancement and Methods PIA, working on mixed neurodegenerative disease, particularly Lewy body and Alzheimer's pathology together. With host Sindhuja Tirumalai Govindarajan she explains why co-pathology is so common and what it means for treatment: does someone with both alpha-synuclein and Alzheimer's pathology respond to an anti-amyloid drug the same way as someone without? They discuss why she leans on fluid biomarkers, the wish for a synuclein PET tracer, and how trials might stratify or include people by co-pathology. Carla makes a useful point for anyone designing research, that clinical trial methods translate straight to observational studies, and previews the CTAM PIA's AAIC programme, including a panel and featured session on global representation in trials.

Takeaways

Mixed pathology is common, and co-occurring alpha-synuclein and Alzheimer's pathology may change how people respond to treatment.
Trials could stratify or include people by co-pathology, but alpha-synuclein is currently detectable only in CSF, which limits that.
Fluid biomarkers offer the specificity to track different proteinopathies and, potentially, response to treatment.
Clinical trial design transfers straight to observational research: the same inclusion criteria, outcomes and sample-size thinking.
Global representation in trials is a live priority, with a CTAM panel launching at AAIC.

There are currently 30 PIAs covering a wide range of interests and fields, from Neuroimaging to Diversity and Disparities and everything in between.

Find out more at https://istaart.alz.org/

A transcript of this show, links and show notes and profile on all our guests are available on our website at https://www.dementiaresearcher.nihr.ac.uk.

If you prefer to watch rather than listen, you will find a video version of this podcast on Apple Podcasts, YouTube, and on our website.

Leave us a tip:

Follow us on social media:

Download and Register with our Community App: