The Michael J. Fox Foundation Parkinson's Podcast

Sleep and Parkinson’s: What’s Going On (and What Can Help) (Webinar Audio)

Wed, 25 Mar 2026 11:45:00 -0400

Sleep is an important part of physical and mental health, but Parkinson’s symptoms and medication side effects can make a good night’s sleep hard to find. Insomnia, nocturia, medication wearing off, REM sleep behavior disorder (RBD) and more can interrupt sleep. Tune into audio from this month’s Third Thursdays Webinar to hear our panel of experts discuss the latest research on the connection between sleep and Parkinson’s disease (PD) and share practical strategies for setting yourself up for the best rest possible.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0

Whether you have Parkinson’s or not, you can help move research forward. Join the study that’s changing everything at michaeljfox.org/podcast-ppmi

Mentioned in this episode:

April is Parkinson’s Awareness Month, and it comes with a chance for you to make a real difference. For people living with Parkinson’s and their loved ones, progress can’t wait — every new discovery, every step forward in research and every bit of your support matters. Visit our website to learn how you can get involved. http://bit.ly/48bPdM3

Catalyzing Community to End Parkinson’s

Wed, 18 Mar 2026 12:00:00 -0400

A world without Parkinson’s will only be made possible through the work and energy of the Parkinson’s community — people living with the disease and their loved ones, researchers, clinicians, industry leaders, lawmakers and others. Catalyzing that community towards productive action is one of The Michael J. Fox Foundation’s (MJFF) four main areas of research focus in its Strategic Research Agenda, along with more clearly defining Parkinson’s disease, building better treatment pipelines and speeding clinical trial decision-making.

In this episode of The Michael J. Fox Foundation Parkinson’s Podcast, part of its award-winning Parkinson’s Science POV series, Maggie Kuhl, vice president of patient engagement at MJFF, leads a conversation about these efforts with two veteran scientists: Brian Fiske, PhD, chief scientist, MJFF and Mark Frasier, PhD, chief scientist, MJFF.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0

There are so many ways to get involved in Parkinson’s community, whether it’s becoming an advocate, joining Team Fox or participating in research. Learn more at michaeljfox.org

The Foundation’s landmark study, the Parkinson’s Progression Markers Initiative, also known as PPMI, is recruiting volunteers. Join the study that’s changing everything at michaeljfox.org/podcast-ppmi

Mentioned in this episode:

In This Together: Care Partnership and Parkinson’s (Webinar Audio)

Tue, 24 Feb 2026 12:45:00 -0400

How can I show up for my partner with Parkinson’s? How can I best support my parent with PD from afar? How can my loved one and I work together to make decisions as symptoms change?

Our community has many questions about how to best support a loved one with Parkinson’s disease. Tune in to audio from this month’s Third Thursdays Webinar to hear our panel of experts — including care partners, a person living with PD, a social worker and a psychologist — discuss strategies for effective communication and shared decision-making to keep a partnership strong through Parkinson’s.

This webinar received support from Acadia Pharmaceuticals. Learn more at: moretoparkinson’s.com

Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0

Whether you have Parkinson’s or not, you can help move research forward. Join the study that’s changing everything at michaeljfox.org/podcast-ppmi.

Mentioned in this episode:

Dishing on Diet for Parkinson’s (Ask the MD Podcast)

Mon, 09 Feb 2026 09:20:00 -0400

Diet is a useful tool to feel and live better, whether you live with Parkinson’s or not. But putting healthy eating into practice can be tricky. In audio from this popular Ask the MD video, movement disorder specialist, lifestyle medicine physician and MJFF Principal Medical Advisor Rachel Dolhun, DipABLM, speaks with Erin Presant, DO, movement disorder and culinary medicine specialist. Together, they answer common questions about how diet can support brain health and help manage disease.

Listen now or watch the video. You can also check out our page on lifestyle strategies for living well with Parkinson’s.

Rather listen on the go? Subscribe to our Michael J. Fox Foundation Parkinson’s Podcast wherever you get your podcasts.

Mentioned in this episode:

Exploring the Link Between Parkinson’s and Alzheimer’s (Webinar Audio)

Mon, 26 Jan 2026 09:14:00 -0400

How does research into Parkinson’s and Alzheimer’s overlap, and what insights are being revealed? Tune into audio from this month’s Third Thursdays Webinar to hear our panel of experts discuss what scientists are learning about how these diseases affect the brain and how understanding their links may lead to better care for people living with a disease.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0

Whether you have Parkinson’s or not, you can help move research forward. Join the study that’s changing everything at michaeljfox.org/podcast-ppmi

Mentioned in this episode:

Lifestyle Strategies to Boost Brain Health (Ask the MD Podcast)

Tue, 20 Jan 2026 09:21:00 -0400

No matter your age, whether you have Parkinson’s or not, there are steps you can take today to boost your brain health. In this extended version of a popular Ask the MD video, movement disorder specialist, life medicine physician and MJFF Principal Medical Advisor Rachel Dolhun, MD, DipABLM, sits down with Ayesha Sherzai, MD, and Dean Sherzai, MD, PhD, known as The Brain Docs. Together they answer community questions and share tips for using lifestyle medicine to help your brain.

Mentioned in this episode:

Stress and Parkinson’s: Strategies to Manage the Strain (Webinar Audio)

Tue, 30 Dec 2025 10:07:00 -0400

Experiencing some stress is a normal part of life, but many people living with Parkinson’s notice stress may worsen symptoms and make medication less effective. And chronic stress can cause lasting impacts to mental and physical health. Tune into audio from this Third Thursday’s Webinar to hear our panel of experts discuss how stress affects the body and how to reduce its harm.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0

Whether you have Parkinson’s or not, you can help move research forward. Join the study that’s changing everything at michaeljfox.org/podcast-ppmi

Mentioned in this episode:

"Building on Breakthroughs" Research Roundtable (Event Audio)

Wed, 17 Dec 2025 11:45:00 -0400

Earlier this year, The Michael J. Fox Foundation hosted its 2025 Research Roundtable, “Building on Breakthroughs.” Tune into audio from this event to hear Parkinson’s experts and MJFF staff discuss the latest in lifestyle medicine and treatments in the pipeline, as well as the power of advocating for Parkinson’s policy.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0

Whether you have Parkinson’s or not, you can help move research forward. Join the study that’s changing everything at michaeljfox.org/podcast-ppmi

Mentioned in this episode:

Parkinson’s Research and Artificial Intelligence

Tue, 09 Dec 2025 12:10:00 -0400

What is AI? How do scientists use it? Where does the data come from? Can AI help find a cure for Parkinson’s?

As the use of artificial intelligence, or AI, becomes more widespread, our community has asked us many questions about how scientists may be using the technology to further Parkinson’s research. In this episode of The Michael J. Fox Foundation Parkinson’s Podcast, in its award-wining "Parkinson’s Science POV" series, Maggie Kuhl, vice president of patient engagement at MJFF, leads a conversation to answer some of those questions with:

Bradford Casey, PhD, senior scientific portfolio manager, MJFF
Brian Fiske, PhD, chief scientist, MJFF
Mark Frasier, PhD, chief scientist, MJFF

Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0

Mentioned in this episode:

Catalyzing Change: Parkinson’s Research Progress in 2025 (Webinar Audio)

Mon, 24 Nov 2025 11:01:00 -0400

Parkinson’s research has had a transformative year as researchers have built on breakthroughs to learn more about the disease and how to treat it. Tune into audio from this Third Thursday’s Webinar to hear our panel of experts discuss how Parkinson’s research has advanced in 2025 and what the future could look like.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0

Whether you have Parkinson’s or not, you can help move research forward. Join the study that’s changing everything at michaeljfox.org/podcast-ppmi

Read more about this year in research at https://viewer.joomag.com/2025-year-in-review/0030141001760361264

Mentioned in this episode:

Genetics and Parkinson’s: Understanding the Role of Gene Therapy in a Cure (Webinar Audio)

Wed, 05 Nov 2025 12:00:00 -0400

What do you know about gene therapy and its potential for treating Parkinson’s? In this audio from our Third Thursdays Webinar, you’ll learn what exactly gene therapy is and how it works, who gene therapy might work for and the role of genetic testing. You’ll also get a status report on investigations into gene therapy for Parkinson’s. Panelists include experts in the field as well as a person with Parkinson’s and her care partner.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your network. https://apple.co/3p02Jw0 

Whether you have Parkinson’s or not, you can help move research forward. Join the study that’s changing everything. Find out more at michaeljfox.com/podcast-ppmi

Mentioned in this episode:

New Treatment Options for Progressing Parkinson’s (Webinar Audio)

Wed, 22 Oct 2025 12:00:00 -0400

As Parkinson’s symptoms change over the years, different treatments may be needed to best manage symptoms and side effects. Since last fall, the U.S. Food and Drug Administration has approved five new options for people living with the disease, including two continuous, under-the-skin infusion pumps. Tune into audio from this Third Thursday’s Webinar to hear our panel of experts discuss these options and other strategies to treat progressing Parkinson’s disease.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0

Whether you have Parkinson’s or not, you can help move research forward. Join the study that’s changing everything at michaeljfox.org/podcast-ppmi.

Mentioned in this episode:

Easing Into Retirement with Parkinson’s

Tue, 07 Oct 2025 10:41:00 -0400

Stepping back from the workforce is a milestone event in any life, and Parkinson’s disease (PD) adds an emotional and logistical layer. Many people living with the disease think differently about when and how to retire as they balance symptoms, their financial and health needs and their plans and interests. Tune into this episode of The Michael J. Fox Foundation’s Parkinson’s Podcast to listen to our expert panel of a person living with Parkinson’s, a care partner and people who work with the Parkinson’s community discuss retirement and Parkinson’s. They share advice from their own lives and tips for people entering a new phase of their life.

Check out our free employment guide. https://www.michaeljfox.org/news/workplace-challenges

Like our podcasts? Rate or review the show and share the series with your community. https://apple.co/3p02Jw0

Mentioned in this episode:

Talking About Disease-modifying Therapies for Parkinson’s (Webinar Audio)

Tue, 23 Sep 2025 14:21:00 -0400

While there have been improvements in therapies to treat Parkinson’s symptoms, people living with the disease and their loved ones await a treatment that will slow the progression of Parkinson’s disease (PD) or stop it entirely. These therapies, called disease-modifying therapies, have the potential to change how PD is treated and experienced. Tune into audio from this Third Thursdays Webinar to listen to our panel of experts discuss disease-modifying therapies and the latest in Parkinson’s research.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0

Whether you have Parkinson’s or not, you can help move research forward. Join the study that’s changing everything at michaeljfox.org/podcast-ppmi.

This webinar was produced with support from Biohaven. https://www.biohavenclinicaltrials.com/clinical-studies/parkinsons-disease/

Mentioned in this episode:

Navigating Employment with Parkinson's

Wed, 10 Sep 2025 12:00:00 -0400

A Parkinson’s disease (PD) diagnosis can impact many areas of life, including how you get work done and think about your career. It can lead to questions like: Should I disclose my diagnosis to my employer and colleagues? How do I adapt my work around my symptoms? What legal protections do I have? Tune into this episode of The Michael J. Fox Foundation’s Parkinson’s Podcast to listen to our expert panel of people living with PD, a care partner, and an employment consultant discuss employment and Parkinson’s. They share their stories and offer the tips they’ve learned along the way.

Check out our free employment guide. https://www.michaeljfox.org/news/workplace-challenges

Like our podcasts? Rate or review the show and share the series with your community. https://apple.co/3p02Jw0

Mentioned in this episode:

Advances in Stem Cell Science for Parkinson’s (Webinar Audio)

Tue, 26 Aug 2025 15:40:00 -0400

Researchers are investigating many options to treat Parkinson’s disease (PD) with stem cells, including reprogramming them to replace lost dopamine-producing neurons and creating supportive brain cells to keep neurons healthy. Tune into audio from this Third Thursdays Webinar to listen to our panel of experts discuss the latest stem cell research and answer audience questions.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0

Whether you have Parkinson’s or not, you can help move research forward. Join the study that’s changing everything at michaeljfox.org/podcast-ppmi.

This webinar was produced with support from BlueRock Therapeutics.

Mentioned in this episode:

Ask Us Anything About Parkinson’s and Relationships

Tue, 19 Aug 2025 09:56:00 -0400

How do I tell my children about my Parkinson’s disease (PD) diagnosis? How do I explain a tremor to my grandkids? How can I support my parent with Parkinson’s from a distance? How can my spouse and I communicate around a symptom of apathy?

Every year our community submits thousands of questions online and at in-person events. Many are about Parkinson’s symptoms, treatment options and the latest research, but we’re also asked questions about relationships and how to maintain connection with loved ones with Parkinson’s in the picture. In this episode of The Michael J. Fox Foundation’s Parkinson’s Podcast, our expert panel tackles questions on relationships and shares their personal experiences and advice.

To connect with others for support and community, join the Parkinson’s Buddy Network. https://parkinsonsbuddynetwork.michaeljfox.org/

Like our podcasts? Rate or review the show and share the series with your community. https://apple.co/3p02Jw0

Mentioned in this episode:

Finding the Right Tech Tools for Your Parkinson’s Journey (Webinar Audio)

Tue, 22 Jul 2025 16:16:00 -0400

Technology can offer people living with Parkinson’s disease (PD) much needed support in several areas of life, from apps to keep track of medication timing, wearables to help smooth gait, websites to monitor symptoms and more. Tune into audio from this Third Thursdays Webinar to listen to our panel of experts discuss how tech tools can be incorporated in daily living with PD and how to find your best options. They also share personal tips and experiences and answer audience questions.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0

Whether you have Parkinson’s or not, you can help move research forward. Join the study that’s changing everything at michaeljfox.org/podcast-ppmi

Mentioned in this episode:

What Imaging Tech Can Reveal About Parkinson's

Wed, 16 Jul 2025 09:29:00 -0400

Advances in imaging technology offer researchers a window into how Parkinson’s disease affects the brain, which could reshape how the disease is diagnosed and treated. In this episode of The Michael J. Fox Foundation Parkinson’s Podcast, in its award-winning Parkinson’s Science POV series, David Kumbroch, senior science writer at MJFF, lead a conversation with:

Jamie Eberling, PhD, senior vice present of research resources at MJFF.
Roger Gunn, PhD, chief science officer at Xing Imaging.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0

Learn more about the many ways to get involved today at michaeljfox.org

Whether you have Parkinson’s or not, you can help move research forward. Join the study that’s changing everything at michaeljfox.org/podcast-ppmi

Mentioned in this episode:

Building Your Best Parkinson’s Care Team (Webinar Audio)

Wed, 09 Jul 2025 10:25:00 -0400

Having a network of health care professionals, loved ones and community members as part of a care team has shown to improve the quality of life for those living with Parkinson’s disease (PD) and their loved ones. Tune into audio from this Third Thursdays Webinar to listen to our panel of experts discuss how to make the most of your appointments, find specialists and coordinate care to best support the person living with the disease.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0

Whether you have Parkinson’s or not, you can help move research forward. Join the study that’s changing everything at michaeljfox.org/podcast-ppmi

Mentioned in this episode:

Understanding the Experience of LGBTQ+ People Living with Parkinson’s Disease

Wed, 18 Jun 2025 09:13:00 -0400

Life with Parkinson’s disease (PD) is shaped by myriad factors, including sexual orientation and gender identity that shape access to care, lifestyle decisions and more. In this episode of The Michael J. Fox Foundation’s Parkinson’s Podcast, our expert panel shares their personal stories and discusses the ongoing research into the health concerns and needs of LGBTQ+ people living with PD.

To connect with others for support and community, join the Parkinson’s Buddy Network. https://parkinsonsbuddynetwork.michaeljfox.org/

Like our podcasts? Rate or review the show and share the series with your community. https://apple.co/3p02Jw0

Mentioned in this episode:

Changing the Narrative: Destigmatizing Parkinson’s Disease (Webinar Audio)

Wed, 28 May 2025 07:04:00 -0400

The beliefs and perceptions that friends, family, employers and even strangers hold about Parkinson’s disease (PD) shape the experience of living with the disease. Facing misperceptions and stigma can cause isolation and worsen symptoms. Tune into audio from this Third Thursdays Webinar to listen to our panel of experts have a candid and compassionate conversation about times they’ve faced stigma, how they’ve navigated it and how they’re working to change misperceptions of Parkinson’s to improve life for everyone living with the disease.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0

Whether you have Parkinson’s or not, you can help move research forward. Join the study that’s changing everything at michaeljfox.org/podcast-ppmi.

Mentioned in this episode:

How Engagement Helps Your Journey with Parkinson's

Tue, 20 May 2025 11:38:00 -0400

There are so many ways to get involved with Parkinson’s disease, from community building to advocacy, research participation to fundraising. Taking that first step toward involvement can be daunting, but many people say it’s a critical part of living well with the disease. In this episode of The Michael J. Fox Foundation Parkinson’s Podcast, members of the Foundation’s Patient Council share stories of their own first steps, explore how engagement has impacted their journeys and offer advice and perspective to others who are looking for ways to make meaningful change. Tune in to hear guest hosts Jimmy Choi, diagnosed with Parkinson’s in 2003, and Hadley Ferguson, diagnosed with multiple system atrophy (MSA-P), an atypical Parkinsonism in 2014, reflect on those stories, recorded live in the MJFF offices.

Learn more about the many ways to get involved today at michaeljfox.org.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0

The Foundation’s landmark study, the Parkinson’s Progression Marker’s Initiative, also known as PPMI, is recruiting volunteers. Join the study that’s changing everything at michaeljfox.org/podcast-ppmi.

Mentioned in this episode:

How Do You Feel with Parkinson’s? A Special Edition Webinar on Emotions (Webinar Audio)

Wed, 23 Apr 2025 10:04:00 -0400

Life with Parkinson’s comes with a vast range of emotions, wherever you are in your disease journey. Shock, grief, optimism, fear, denial, hope, humor and more can all be a part of the emotional landscape for people living with the disease and their loved ones. Tune into audio from this special edition Third Thursdays Webinar to listen to our panel of experts have a frank and deep conversation about how they’ve navigated their feelings over the years, how they’ve managed challenging emotions and what lifts them up and brings them hope.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0

Mentioned in this episode:

Sniff Test: Surprising New Learnings About Smell Loss and Parkinson’s (Webinar Audio)

Wed, 26 Mar 2025 13:32:00 -0400

Smell loss can be among the earliest signs of Parkinson’s disease (PD) and other neurodegenerative diseases, signaling changes in the brain years before other symptoms are noticeable. Because of the link between smell and brain health, researchers are very interested in understanding more about how people with smell loss go on to either develop a disease or not, and why some people with PD still are able to smell. To learn more about the latest research, tune into audio from this Third Thursdays Webinar and listen to expert panelists discuss the science of smell and what scientists are learning about its connection to disease.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0

Mentioned in this episode:

What Parkinson’s Genetics Mean for Personal Experience and Research

Mon, 17 Mar 2025 14:14:00 -0400

You could take any two humans on earth and their genetic code will be roughly 99 percent the same — it’s the small differences in code that lead to different experiences and outcomes, including the risk of developing diseases like Parkinson’s. Scientists are learning more about which genetic changes are linked to Parkinson’s disease, revealing important insights into disease biology and progression. Tune into this episode of our award-winning “Parkinson’s Science POV” series to learn how researchers are using genetics to better understand the disease and work toward better treatments for all.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0

This episode was made possible by Prevail Therapeutics. Partner support allows us to furnish high-quality educational content to the Parkinson's community while maintaining our commitment to allocate donor dollars to high-impact research. Editorial control of all Michael J. Fox Foundation-published content rests solely with the Foundation.

Mentioned in this episode:

The Path to a Parkinson’s Drug Approval (Webinar Audio)

Wed, 26 Feb 2025 10:52:00 -0400

With three new Parkinson’s treatments approved in the last year, there are more options than ever before for people living with the disease. Tune into audio from this Third Thursdays Webinar to hear movement disorder specialists, research experts and a person living with Parkinson’s answer community questions about the new treatments available, explain how therapies make it through FDA approval and share the latest on treatments in the pipeline.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0

Mentioned in this episode:

What’s in Your Parkinson’s Medicine Cabinet (Ask the MD Podcast)

Tue, 11 Feb 2025 10:14:00 -0400

Movement disorder specialist, lifestyle medicine physician and MJFF Principal Medical Advisor Rachel Dolhun, MD, DipABLM, shares tips on medication management for people at every stage of the disease journey.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0

Mentioned in this episode:

Managing the Hidden Symptoms: Mood and Motivation Changes in Parkinson’s (Webinar Audio)

Wed, 22 Jan 2025 10:15:00 -0400

If depression, anxiety or apathy occur as part of a Parkinson’s journey, it can be easy to feel alone, isolated or unsure of what might bring relief. But there are ways to manage these symptoms. Tune into audio from this Third Thursdays Webinar to hear people living with Parkinson’s share their stories of coping with mood changes as well as a movement disorder specialist and psychiatrist discuss pharmacological and non-pharmacological treatments options.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0

Mentioned in this episode:

Your Top Questions on Parkinson’s and Exercise Answered (Ask the MD Podcast)

Wed, 15 Jan 2025 12:00:00 -0400

Movement disorder specialist, lifestyle medicine physician and MJFF Principal Medical Advisor Rachel Dolhun, MD, DipABLM, answers community questions on Parkinson’s and exercise with physical therapist and rehab scientist Cristina Colón-Semenza, PhD.

Listen to the audio or watch the video.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0

Mentioned in this episode:

Parkinson’s Care Partners: Not Another “Self-Care” Discussion (Webinar Audio)

Wed, 08 Jan 2025 11:55:00 -0400

Being a care partner to someone with Parkinson’s disease (PD) can be a shifting and complex role, as symptoms and life circumstances change. And sometimes, this can lead to stress and even burnout for the care partner. Tune into audio from this Third Thursdays Webinar to hear expert panelists discuss how to navigate care partnership, including everyday strategies to de-stress and find supportive community.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0

Mentioned in this episode:

The Role of Diet and Nutrition in Parkinson’s Disease and Brain Health with Puja Agarwal

Tue, 31 Dec 2024 03:00:00 -0400

It is widely known that a healthy diet can provide essential nutrients and lead to a multitude of benefits, but growing evidence has highlighted important links between diet, nutrition, and brain health, particularly related to neurodegenerative disease. In this episode, Dr. Puja Agarwal discusses her research investigating the role that diet and nutrition may play in Parkinson’s disease and other neurodegenerative conditions. Evidence from her studies and the work of others suggests that certain diets, including the Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet, are associated with brain health and may have the potential to delay the onset or slow progression of Parkinson's disease or other neurodegenerative conditions. We hear more about her ongoing MJFF-funded research project examining the role of diet in the progression of parkinsonian signs and its association with Lewy body pathologies, as well as future directions for this exciting line of research. Puja is an Assistant Professor in the Department of Internal Medicine at Rush University.

Mentioned in this episode:

This podcast episode was part of a limited series created by The Michael J. Fox Foundation in 2023 and 2024 for clinicians and researchers in our audience. These episodes provide a deeper dive into exciting new scientific research in Parkinson’s disease, as well as innovative tools and valuable resources, through conversations with a variety of experts in the field. We hope you enjoy the conversation.

Developing a Novel App to Improve Speech Intelligibility in Parkinson's Disease with Gemma Moya-Galé

Tue, 17 Dec 2024 03:00:00 -0400

Parkinson's disease significantly impacts various aspects of communication, and this can make it challenging for people with the disease to communicate effectively, be understood by others, and engage in social situations. Dr. Gemma Moya-Galé joins this episode to talk about her work on voice and communication in people with Parkinson’s disease. In particular, she discusses a novel app she and her team are developing, with funding from The Michael J. Fox Foundation, to help people with Parkinson’s improve how well their speech is understood. The app uses evidence-based principles from speech therapy and noise-augmented automatic speech recognition to provide speech training and feedback. She also shares her recent research on linguistically and culturally responsive methods for addressing communication challenges in both English- and Spanish-speaking individuals with Parkinson's disease, and how this approach has the potential to improve clinical care. Gemma is an Assistant Professor of Communication Sciences and Disorders, as well as the Director of the Communication, Technology, and Language Diversity Lab at Teachers College, Columbia University.

Mentioned in this episode:

MJFF Scientists Share How Their Work Could Transform Parkinson's Care

Wed, 11 Dec 2024 12:00:00 -0400

Understanding the biology of Parkinson’s disease (PD) and turning that knowledge into better treatments is a complex undertaking. In this episode of the award-winning Parkinson’s Science POV series, scientists at The Michael J. Fox Foundation (MJFF) discuss how they are tackling this problem from every angle. Whether it’s using cutting-edge imaging to get a picture of the disease in the brain or working with the community to develop better options to treat walking difficulties, our researchers are collaborating to discover the next wave of treatment options and close in on a cure.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0

Watch our webinar or read our Year in Review at michaeljfox.org.

Mentioned in this episode:

Increasing Diversity in Research and Addressing Brain Health Inequities with Monica Rivera-Mindt

Tue, 03 Dec 2024 03:00:00 -0400

Certain populations are disproportionately affected by neurological diseases, including Parkinson's and other neurodegenerative diseases. A lot of work remains to be done to improve brain health outcomes and promote healthy brain aging across the lifespan, particularly for minoritized, underrepresented populations. Including participants from diverse backgrounds in research helps ensure that the results from studies and clinical trials in the field are valid, generalizable, and representative of all individuals affected by these diseases.

In this episode, Dr. Monica Rivera-Mindt discusses brain health inequities in neurodegenerative diseases, her work using culturally informed community-engaged research methods to improve representation in research studies, important gaps in the literature, lessons learned from the Alzheimer's Disease Neuroimaging Initiative (ADNI) Diversity Task Force that could be applied in Parkinson's disease research, and more. Monica is Professor of Psychology, Latinx studies, and African and African American studies at Fordham University, and she has a joint appointment as Professor of Neurology at the Icahn School of Medicine at Mount Sinai. She is also a board-certified neuropsychologist.

Mentioned in this episode:

Year of Momentum: What Parkinson’s Research Accomplished in 2024 (Webinar Audio)

Wed, 27 Nov 2024 12:00:00 -0400

With two new drugs approved by the FDA, a National Plan signed into law and many advances in our understanding of Parkinson’s disease, 2024 has been a transformative year in Parkinson’s research. Tune into audio from this month’s Third Thursdays Webinar to hear research experts from industry and academia talk with MJFF staff about the latest research on disease biology and emerging therapies.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0

Mentioned in this episode:

The Development and Application of the Alpha-Synuclein Seed Amplification Assay with Claudio Soto

Tue, 19 Nov 2024 03:00:00 -0400

Alpha-synuclein plays a key role in the pathophysiology of Parkinson's disease, and researchers have been investigating this protein as a therapeutic target and also as a potential biomarker for the disease. The alpha-synuclein seed amplification assay, developed by Dr. Claudio Soto and colleagues, leverages the self-replicating nature of the misfolded alpha-synuclein proteins that form aggregates in Parkinson's disease. Amplifying misfolded alpha-synuclein can allow researchers and clinicians to detect the presence of the pathological form of the protein in biospecimens, even when the amount of misfolded alpha-synuclein in a sample is very low. In this episode, Claudio discusses his work in this area and how it has opened the doors for a variety of potential uses of the alpha-synuclein seed amplification assay, including applications in diagnosis, clinical trials, and drug development for Parkinson's disease.

This year, Claudio received the 2024 Robert A. Pritzker Prize for Leadership in Parkinson’s Research for his substantial contributions to research and his commitment to mentoring the next generation of scientists in the field. Claudio is the Huffington’s Distinguished University Chair, Professor of Neurology, and Director of the George and Cynthia Mitchell Center for Alzheimer’s Disease and Related Brain Disorders at The University of Texas Medical School in Houston. He is also the Founder, Vice-President, and Chief Scientific Officer at AMPRION Inc.

Mentioned in this episode:

Ask Us Anything About Deep Brain Stimulation Surgery Day

Wed, 13 Nov 2024 12:00:00 -0400

Each person living with Parkinson’s disease (PD) will have a unique journey with their treatments, including the decision to have deep brain stimulation (DBS), which is a surgical procedure to treat Parkinson’s motor symptoms. While DBS isn’t suitable for everyone, it can be helpful in the right person, and it’s a complex, lifelong choice. And although the experience goes far beyond surgery day, brain surgery often looms large in people’s minds as they are contemplating DBS. In this episode, our expert panelists tackle community-sourced questions on DBS surgery day: what to wear, how loved ones can support, what it feels like to be awake during brain surgery and more. Tune in to hear from two people who have had DBS, a neurosurgeon and a movement disorder specialist and learn more about the realities of surgery day.

For more information on deep brain stimulation, download our newly updated, comprehensive guide or check out our webinar at michaeljfox.org.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your community: https://apple.co/3p02Jw0

The Foundation’s landmark study, the Parkinson’s Progression Marker’s Initiative, also known as PPMI, is recruiting volunteers. People from all backgrounds with and without Parkinson’s can help move research forward. Join the study that’s changing everything at michaeljfox.org/podcast-ppmi.

Mentioned in this episode:

An Inside Look at the Edmond J. Safra Fellowship in Movement Disorders with Marcelo Merello and Sergio Castillo-Torres

Tue, 05 Nov 2024 03:00:00 -0400

To help meet the growing global need for more movement disorders specialists, The Michael J. Fox Foundation created the Edmond J. Safra Fellowship in Movement Disorders in collaboration with longtime partner the Edmond J. Safra Foundation. This program supports the training of movement disorders specialists who will provide expert care and drive advances in Parkinson's research. The program is positively impacting early-career clinician-researchers, as well as the centers where they train. These impacts will continue to grow over the years as more fellows are trained. In this episode, Dr. Marcelo Merello and Dr. Sergio Castillo-Torres share their insights and perspectives as a Fellowship Director and a Fellow in the program, respectively.

Marcelo is Director of the Department of Neurosciences and Chief of the Movement Disorders Clinic at the Institute for Neurological Research or Fleni Hospital. He is fellowship Director at Fleni and the University of Buenos Aires. In addition, Marcelo is Principal Investigator with the National Council for Scientific and Technical Research and Professor of Neurodegenerative Diseases at the Pontifical Catholic University of Argentina. Sergio is an Associate Professor in Neurology and Internal Medicine at the Dr. Jose E. Gonzales University Hospital of the Autonomous University of Nuevo Leon. He was an Edmond J. Safra Fellow in Movement Disorders at Fleni Hospital. Visit michaeljfox.org/fellowship to learn more about the Edmond J. Safra Fellowship in Movement Disorders.

Mentioned in this episode:

Hitting Stride: Research Advances on Walking with Parkinson’s (Webinar Audio)

Wed, 23 Oct 2024 12:00:00 -0400

Troubles with gait – slow walking, shuffling steps and foot dragging and more – can be symptoms of Parkinson’s. In audio from this Third Thursdays Webinar, our experts explore the robust research efforts underway to understand and treat gait issues, from physical rehab interventions to deep brain stimulation modifications to wearable robots designed to smooth gait.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0

Mentioned in this episode:

Creating Alpha-Synuclein Cell Lines and Supporting Open Science with Birgitt Schüle

Tue, 15 Oct 2024 03:00:00 -0400

Stem cell models derived from patients with Parkinson’s disease are valuable tools that are helping researchers around the world to better understand the underlying causes of neurodegeneration and to develop biomarkers and new therapies. To maximize the potential impacts of these tools, it is critical that they are developed and shared according to the principles of open science. In her interview, Dr. Birgitt Schüle discusses her work developing alpha-synuclein cell lines, challenges and opportunities in the field, and important considerations surrounding open science. She goes in-depth on how the cell lines were developed, characterized, and deposited with the American Tissue and Cell Collection (ATCC) with funding support from The Michael J. Fox Foundation, as well as how these cells can be used to fuel future discoveries. Birgitt is an Associate Professor in the Department of Pathology at Stanford University School of Medicine and Co-Director of the Alzheimer’s Disease Research Center, Neuropathology, and Induced Pluripotent Stem Cell (iPSC) Core.

Mentioned in this episode:

Perspectives on Navigating Racial Bias and Stigma in Parkinson's Disease

Wed, 09 Oct 2024 12:00:00 -0400

In this podcast, four people from different backgrounds have a candid conversation on race, stigma and Parkinson’s. They share their experiences trying to find culturally competent medical professionals, overcoming the barriers to research participation, and communicating with their communities about their diagnosis. And they offer tips and advice on finding empowerment through education and advocacy.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your community: https://apple.co/3p02Jw0

The Foundation’s landmark study, the Parkinson’s Progression Marker’s Initiative, also known as PPMI, is recruiting volunteers. People from all backgrounds with and without Parkinson's can help move research forward. Join the study that’s changing everything at michaeljfox.org/podcast-ppmi.

Mentioned in this episode:

Developing FLEXISyn to Identify and Measure Changes in Alpha-Synuclein in Parkinson's Disease with Judith Steen

Tue, 01 Oct 2024 03:00:00 -0400

New qualitative and quantitative tools are being developed to measure and track changes in proteins relevant for neurodegenerative disease, and these tools have the potential to accelerate drug discovery and clinical trials. In this episode, Dr. Judith Steen discusses her work creating novel qualitative and quantitative tools and workflows at the interface of proteomics and transcriptomics, including their novel FLEXI platform. This platform uses targeted, high- throughput quantitative mass spectrometry to isolate, quantify, and identify molecular changes in proteins. She describes her ongoing project, funded by The Michael J. Fox Foundation, to develop FLEXISyn, which aims to track post-translational changes in alpha-synuclein to better understand how the protein becomes dysfunctional and begins misfolding and forming toxic aggregations in Parkinson's disease. Judith is Associate Professor of Neurology at Harvard Medical School, a member of the Harvard Stem Cell Institute, and Director of the Neuroproteomics Laboratory in the F.M. Kirby Neurobiology Center at Boston Children's Hospital.

Mentioned in this episode:

A Conversation on Parkinson’s-Related Hallucinations and Delusions (Webinar Audio)

Wed, 25 Sep 2024 12:00:00 -0400

Parkinson’s disease brings with it many potential symptoms, including hallucinations (seeing things that are not there) and delusions (believing things that are not true). Not everyone will experience these symptoms and not everyone who does will find them bothersome, but it can be a source of uncertainty and concern for people living with the disease. In audio from this Third Thursdays Webinar, our expert panel discusses navigating life with these symptoms and medication and non-medication strategies to manage them.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0

Mentioned in this episode:

Clinical Applications of Biomarkers and Large-Scale Collaborative Research with Charles Adler

Tue, 17 Sep 2024 03:00:00 -0400

Substantial research has focused on identifying biomarkers for the diagnosis of Parkinson's disease (PD) as well as monitoring progression of the disease. In developing these biomarkers, it is critical for scientists to consider how the biomarkers will ultimately be used in the clinic and in clinical trials research. In this interview, Dr. Charles (Chuck) Adler shares his perspectives on how biomarkers are currently being used in clinical and research contexts, and what it would take for him to use them more often in clinical practice. He also discusses how groundbreaking collaborative research studies, including the Arizona Study of Aging and Neurodegenerative Disorders and the Parkinson's Progression Markers Initiative (PPMI), are having major impacts on the field. Chuck is Consultant and Professor of Neurology in the Department of Neurology and The Wayne and Kathryn Preisel Professor of Neuroscience Research at the Mayo Clinic Alix School of Medicine at the Mayo Clinic in Arizona.

Mentioned in this episode:

Investigating Light Therapy For Sleep and Motor Function in People with PD with Beatrix Feigl

Tue, 03 Sep 2024 03:00:00 -0400

Sleep disturbances, such as insomnia, sleep fragmentation, excessive daytime sleepiness, and REM sleep behavior disorder are common in people with Parkinson's disease (PD). Poor sleep quality can also impact other domains of function, including motor function. Prior research has shown that a type of photoreceptor cell in the retina, called melanopsin cells, provide the main light signals to the brain to initiate sleep, and function of these cells is impaired in PD. Dr. Beatix Feigl and her colleagues developed a novel light therapy intervention that selectively activates the melanopsin photoreceptor cells, and in this episode, she discusses the results of a recent randomized controlled trial evaluating the efficacy of this melanopsin photoreceptor-directed light therapy on sleep and circadian rhythm, as well as motor behaviors. She also discusses her earlier work on melanopsin cells that led to the development of standard measures to assess their function. Beatrix is an Ophthalmologist and an Associate Professor in the School of Biomedical Sciences and Center for Vision and Eye Research, as well as the Faculty of Health, at the Queensland University of Technology.

Mentioned in this episode:

Your Daily Dose: Managing Parkinson’s Medications (Webinar Audio)

Wed, 21 Aug 2024 12:00:00 -0400

Finding the right Parkinson’s treatment plan can be a trial-and-error process. The kind of medication, the dosage, the timing and lifestyle factors are all important pieces of the puzzle. In audio from this Third Thursdays Webinar, our expert panel made up of people living with Parkinson’s disease (PD), a movement disorder specialist and a researcher discuss different medication options, practical tips for finding what works best for you and the latest research on emerging treatments.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0

Mentioned in this episode:

The Autophagy-Lysosomal Pathway and Development of Relevant PD Biomarkers with Zhenyu Yue

Tue, 20 Aug 2024 03:00:00 -0400

Though existing evidence supports that dysfunction in the clearing of cellular debris plays an important role in the development of Parkinson's disease, many unanswered questions remain regarding the mechanisms of the autophagy-lysosomal pathway involved in this process. In particular, research in the field has been limited by a lack of reliable, quantitative tests for monitoring autophagy-lysosome activity. In this interview, Dr. Zhenyu Yue describes his research investigating the cellular and molecular mechanisms for Parkinson's disease and other neurodegenerative diseases, focusing on their work examining the regulation of the autophagy-lysosomal pathway, potential therapeutic targets, and MJFF-funded research that aims to develop sensitive, robust autophagy-lysosome assays to facilitate the discovery of biomarkers for PD using stem cell-derived neurons and biofluids. Zhenyu is the Aidekman Research Professor in the Department of Neurology and Friedman Brain Institute at the Icahn School of Medicine at Mount Sinai. He is also the Director of the Center of Parkinson’s Disease Neurobiology and Director of Basic Research of Movement Disorders at Mount Sinai.

Mentioned in this episode:

Breathing Through: Mindfulness as a Parkinson's Treatment Tool

Wed, 14 Aug 2024 12:00:00 -0400

Research shows mindfulness and meditation can improve some Parkinson’s (PD) symptoms and help people live a better life with the disease, but it can be tricky to put into practice. In this podcast, you’ll hear from people whose lives have been touched by PD and who use mindfulness to reduce symptoms and stress, and from a researcher who is studying how mind-body strategies can be used to treat Parkinson’s. Tune in for practical tips, advice and a guided meditation you can try at home.

You can find links to the resources mentioned in the episode on our website: michaeljfox.org/podcast/breathing-through-mindfulness-parkinsons-treatment-tool

You can also download our free guide on exercise and Parkinson’s disease, which includes tips for incorporating meditation into your daily routine at michaeljfox.org/exerciseguide

Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0

Mentioned in this episode:

Studying CSF Element Profiles and Tear Fluid as Potential Biomarkers, and Novel and Combined Therapies for PD with Paul Lingor

Tue, 06 Aug 2024 03:00:00 -0400

Evidence supports that dysfunction in the homeostasis of iron and other elements likely contributes to the pathophysiological mechanisms of Parkinson's disease, but we have yet to develop suitable elemental biomarkers for use in diagnosing and monitoring the progression of Parkinson's disease. Dr. Paul Lingor discusses his work in this area to identify patterns of bioelements in CSF that could serve as PD biomarkers. Beyond CSF, he is also examining tear fluid as a potential biomarker source that is easier to collect. In addition to work on biomarkers, Paul has been involved in developing and evaluating new treatments for Parkinson's disease. In this episode, he discusses an ongoing phase II clinical trial evaluating the ROCK inhibitor Fasudil, as well as research examining combinations of advanced therapies for people with later-stage Parkinson's disease. Paul is Professor of Neurology at the Technical University of Munich and head of the outpatient clinics for motor neuron disease and co-head of the outpatient clinics for Parkinson’s disease.

Mentioned in this episode:

Considering Deep Brain Stimulation: What to Know and Expect (Webinar Audio)

Wed, 24 Jul 2024 12:00:00 -0400

The decision-making process around deep brain stimulation (DBS) to treat Parkinson’s motor symptoms can be a complex and emotional journey. People often have questions about when – and whether – to have the procedure and what the experience is like, from the months of evaluation pre-surgery to surgery day to life with the device. In audio from this Third Thursdays Webinar, our panel of people living with Parkinson’s disease (PD) and a movement disorder specialist share their DBS stories and answer audience questions about their choices and experiences.

Learn more about deep brain stimulation and download our free guide on our website: https://bit.ly/4cTOT52

Like our podcasts? Please consider leaving a rating or review and sharing the series with your community.

Mentioned in this episode:

Current and Emerging Imaging Biomarkers for Diagnosis and Prognosis of PD and Atypical Parkinsonism with Antonio Strafella

Tue, 23 Jul 2024 03:00:00 -0400

Identifying reliable biomarkers for the diagnosis and prognosis of Parkinson's disease and atypical parkinsonism would have substantial impacts on clinical trials and clinical practice. A particularly active area of research is the development of novel molecular imaging biomarkers that can be used in combination with common neuroimaging approaches. Dr. Antonio Strafella discusses current practices for using molecular imaging biomarkers in research and in the clinic, the process of developing new biomarkers, as well as promising biomarkers that are in development. He also discusses limitations, implementation challenges, and the potential use of AI to enhance diagnostics in the future. Antonio is the Krembil-Rossy Chair in Molecular Imaging of Neurodegenerative Diseases and Professor in the Department of Medicine within the Division of Neurology at the Toronto Western Hospital (University Health Network, University of Toronto). He also serves as Director of Clinical Research and Translation with the Temerty Faculty of Medicine at the University Toronto, and he is a movement disorder neurologist in the Edmond J. Safra Program in Parkinson’s Disease and Morton & Gloria Shulman Movement Disorders Clinic at the Toronto Western Hospital.

Mentioned in this episode:

Building on the Biomarker Breakthrough: What We’re Working on Now

Wed, 10 Jul 2024 12:00:00 -0400

Just over a year ago, there was a major breakthrough in Parkinson’s disease (PD) research – a tool that could detect abnormal alpha-synuclein protein in the spinal fluid of people living with PD even before onset of symptoms. This discovery is already impacting the ways scientists conduct and think about Parkinson’s research. Tune into this episode of our award-winning “Parkinson’s Science POV” series to learn how researchers are using the test to better understand disease biology and what the future holds.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0

Mentioned in this episode:

Examining Links Between Environmental Exposure, Poor Olfaction, and Parkinson's Disease with Honglei Chen

Tue, 09 Jul 2024 03:00:00 -0400

Prior studies have established links between poor olfaction and Parkinson's disease, and impaired sense of smell is a common prodromal symptom of Parkinson's disease. The causes and mechanisms of prodromal neurodegeneration are actively being researched. However, environmental exposure to pesticides or other chemicals may trigger or modify the course of neurodegeneration, potentially leading to the development of Parkinson's disease over time. In this episode, Dr. Honglei Chen shares his research on environmental causes of neurodegenerative diseases, focusing particularly on evidence linking olfaction, environmental exposure, and Parkinson’s disease. Better understanding how environmental factors may contribute (alone or in combination with genetic factors) to the pathogenesis of Parkinson's disease may lead to new approaches to prevent or slow the progression of neurodegeneration. Honglei is the MSU Research Foundation Professor of Epidemiology and Biostatistics at Michigan State University.

Mentioned in this episode:

You Want to Volunteer for Parkinson’s Research: Now What? (Webinar Audio)

Wed, 26 Jun 2024 12:00:00 -0400

You might be interested in stepping forward for science to play a role in the next breakthrough in Parkinson’s research, but still have questions about how to actually participate. How do you pick the right study for you? How do you balance your life logistics and your medical care considerations? What rights do you have when you participate in a study? In audio from this Third Thursdays Webinar, our panel of people living with Parkinson’s and research experts discuss the practicalities and benefits of volunteering for research.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0

Mentioned in this episode:

Developing Interventions to Improve Gait and Increase Physical Activity in Parkinson’s Disease with Gammon Earhart

Tue, 18 Jun 2024 03:00:00 -0400

Gait impairments such as slow speed, small steps, and high variability from step to step are common in people with Parkinson's disease, and these changes begin to occur early in the course of disease. Freezing of gait may develop later for some individuals, and it has been linked to falls and other adverse outcomes. When the quality of walking declines, it can lead to a reduction in the quantity of walking and overall physical activity, which is also related to poorer health outcomes. To prevent this cascade of events, Dr. Gammon Earhart is developing and evaluating interventions to improve gait and increase physical activity in People with Parkinson's disease. In this episode, she discusses how she and collaborators are conducting studies on different approaches, including a mobile health application, self-generated rhythmic cues in the form of singing, and mindfulness training, to improve aspects of walking and physical activity in people with Parkinson's disease. Gammon is Professor of Physical Therapy, Neurology, and Neuroscience, Associate Dean for Physical Therapy, and Director of the Program in Physical Therapy at Washington University School of Medicine in St. Louis.

Mentioned in this episode:

Studying Basal Ganglia Circuits and Developing Deep Brain Stimulation Protocols for Longer-Lasting Effects with Aryn Gittis

Tue, 04 Jun 2024 03:00:00 -0400

Improving our understanding of the complex neural circuits involved in normal function of the basal ganglia and other parts of the brain impacted by Parkinson's disease is critical for developing more targeted and more effective treatment approaches. In this episode, Dr. Aryn Gittis discusses her research examining how the activity of specific basal ganglia circuits relates to motor control in both health and pre-clinical models of movement disorders like Parkinson's disease. She describes new research on basal ganglia circuits that expands upon existing theoretical frameworks and provides important insights that can be leveraged to improve current therapies for Parkinson's disease by better targeting specific cell types in relevant circuits. Aryn also shares details about her ongoing project evaluating the impacts of stimulus location for a novel pattern of deep brain stimulation (DBS) that has been shown to provide long-lasting therapeutic effects in pre-clinical models. Aryn is Professor of Biological Sciences and the Neuroscience Institute at Carnegie Mellon University.

Mentioned in this episode:

When Parkinson’s Hurts: Treatments for Managing Pain (Webinar Audio)

Wed, 29 May 2024 12:00:00 -0400

Many people living with Parkinson’s disease (PD) experience pain as a non-motor symptom. Pain can arise from stiff muscles, dystonia, nerve pain and even the disease progression itself. It’s a symptom that some find difficult to talk about, but there are options for people to find relief. In audio from this Third Thursdays webinar, listen to our expert panel of people living with PD, movement disorder specialists, and an integrative pain specialist discuss pain and Parkinson’s – why it happens, treatments to reduce it, and practical tips you can start incorporating today.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your community. https://apple.co/3p02Jw0

Mentioned in this episode:

Innovative Fellowship Program is Training Tomorrow's Parkinson's Leaders with Rachel Dolhun

Tue, 21 May 2024 03:00:00 -0400

Demand for movement disorder specialists continues to grow, but not enough neurologists are receiving focused training in Parkinson’s and related conditions in order to meet the current and projected needs in the U.S. and around the world. In collaboration with longtime partner the Edmond J. Safra Foundation, The Michael J. Fox Foundation created the Edmond J. Safra Fellowship in Movement Disorders with the goal of growing the global base of movement disorders specialists. In this episode Dr. Rachel Dolhun shares more about this fellowship program, the application process, and how the program supports the training of movement disorders clinician-researchers who will become leaders in Parkinson's care and advance science in the field. Rachel is Senior Vice President of Medical Communications at The Michael J. Fox Foundation for Parkinson's Research. Visit michaeljfox.org/funding to learn more about the Edmond J. Safra Fellowship in Movement Disorders.

Mentioned in this episode:

What I Wish I Had Known at Diagnosis

Wed, 15 May 2024 12:00:00 -0400

In this episode, hosted by Larry and Rebecca Gifford, members of The Michael J. Fox Foundation’s Patient Council and their care partners share their honest reactions to their diagnosis — from panic and denial to sadness and loneliness. This group of men and women of different ages and backgrounds offers words of wisdom about what to consider, what they’ve lost and what they’ve gained – and you’ll be surprised to hear how, for some, what they’ve gained is more than what they lost.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your network. https://apple.co/3p02Jw0   

If you or a loved one was recently diagnosed and you’re wondering where to start, visit https://www.michaeljfox.org/newlydiagnosed to find helpful resources, including an educational guide, support groups and videos.

Whether you’ve been newly diagnosed or have been living with Parkinson’s for many years, The Michael J. Fox Foundation’s Parkinson’s Buddy Network is a free, online platform that helps you find new connections, access educational resources and engage in important dialogue. Join our community today at parkinsonsbuddynetwork.org. 

Mentioned in this episode:

Real Talk from Women Living with Parkinson’s

Wed, 08 May 2024 12:00:00 -0400

In this raw and emotional conversation, four women with Parkinson’s living in four different countries discuss the challenges faced because of delayed diagnosis, hormonal changes, lack of information and treatment, research inequity and gender biases. They share how they live better with the disease by advocating for themselves with their health care team and how they empower other women through awareness and activism.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your network. https://apple.co/3p02Jw0   

Connect with other women who share your experiences with Parkinson’s. The Michael J. Fox Foundation’s Parkinson’s Buddy Network is a free, online platform that helps you find new connections, access educational resources and engage in important dialogue. Join our community today at parkinsonsbuddynetwork.org.

Mentioned in this episode:

Evidence Linking Parkinson's Disease Risk and Environmental Exposure to Trichloroethylene (TCE) with Sam Goldman

Tue, 07 May 2024 03:00:00 -0400

Trichloroethylene (TCE) and related chemicals like perchloroethylene (PCE) have been used widely for a variety of commercial purposes over the past century, and these chemicals are prevalent in the air, water, and soil. Over the past several decades, mounting evidence has been published linking exposure to TCE/PCE with adverse health effects, including cancer and Parkinson's disease. In this episode, Dr. Sam Goldman discusses his research on environmental risk factors for Parkinson’s disease, focusing on recently published studies examining Parkinson's disease risk in Veterans at Camp Lejeune and also a cluster analysis investigating parkinson's disease diagnoses in people who worked near a contaminated site. Sam is a Professor in the Division of Occupational, Environmental, and Climate Medicine and the Departments of Medicine and Neurology at the University of California, San Francisco (UCSF). He is also a Principal Investigator in the San Francisco Veterans Affairs Medical Center.

Mentioned in this episode:

Let’s Talk Taboos: Hard-To-Discuss Parkinson’s Symptoms (Webinar Audio)

Wed, 24 Apr 2024 12:00:00 -0400

Living with Parkinson’s comes with a variety of symptoms, some of which can be unexpected, and frankly, embarrassing. Drooling, bladder issues and sexual dysfunction are hard to talk about, even with loved ones or your doctor – and can affect your self-image, your intimate relationships or the way you move through the world. In audio from this Third Thursdays webinar, listen to our expert panel of people living with Parkinson’s, a care partner and a movement disorder specialist discuss Parkinson’s taboo topics and ways that you can navigate hard conversations and embarrassment.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your network. https://apple.co/3p02Jw0

Mentioned in this episode:

New Advances in Neurosurgical Interventions for Parkinson's Disease with Doris Wang

Tue, 16 Apr 2024 03:00:00 -0400

For over a century, different surgical interventions have been explored to address symptoms of Parkinson's disease, and researchers are continuing to innovate and improve surgical treatments today. With new technology and an ever-expanding understanding of the function of the nervous system and the pathophysiology of Parkinson's disease, neurosurgical interventions are becoming more effective and more personalized. Dr. Doris Wang joins us in this episode to discuss her work using focused ultrasound and deep brain stimulation (DBS) as treatments for Parkinson’s disease and other movement disorders. She discusses some of the benefits and limitations of focused ultrasound treatment, comparisons of traditional versus asleep interventional MRI-guided deep brain stimulation surgery, advances in adaptive deep brain stimulation, and the development of gait-related biomarkers that could drive adaptive DBS. Doris is a neurosurgeon and Associate Professor in the Department of Neurological Surgery at the University of California, San Francisco (UCSF).

Mentioned in this episode:

Accelerating Discovery by Developing and Distributing Research Tools with Nicole Polinski

Tue, 02 Apr 2024 03:00:00 -0400

The Michael J. Fox Foundation for Parkinson's Research established its Research Tools Program to address gaps in the field and common challenges surrounding the development of reagents and models that slowed the initial stages of promising research projects. In collaboration with many partners and stakeholders, the Research Tools Program helps ensure that scientists around the world have access to high-quality reagents, models, and more. These tools have been instrumental in launching novel research projects to better understand Parkinson's disease and to develop promising new treatment strategies. This episode features Dr. Nicole K. Polinski, Director of Research Resources at The Michael J. Fox Foundation for Parkinson’s Research. In our conversation, she discusses her role in the organization, the wide variety of tools available through the Research Tools Program, and how academic and industry researchers can share their insights and feedback on current tools and future directions for tool development.

Mentioned in this episode:

Everyday Exposures to Parkinson’s: Environmental Connections to the Disease (Webinar Audio)

Wed, 27 Mar 2024 12:00:00 -0400

The biology behind what causes Parkinson’s is complex, with only about a quarter of cases with clear genetic drivers. The environment – where you live, the air you breathe, the food you eat, the world around you – plays a key role in PD. Emerging research is showing environmental exposures to things like pesticides and pollution may interact with a person’s genetics and contribute to the disease. And there’s a myriad of other factors still being investigated, from the forces that drive your access to neighborhoods with clean air and water, good doctors and healthy living opportunities to psychosocial factors like stress and discrimination. In audio from this Third Thursdays Webinar, listen to our expert panel discuss the latest research and ways you can get involved to end preventable exposures and advocate for Parkinson’s policy.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your network. https://apple.co/3p02Jw0  

Mentioned in this episode:

The Importance of Sex and Gender Factors in Neurodegenerative Disease Research and Care with Antonella Santuccione Chadha

Tue, 19 Mar 2024 03:00:00 -0400

Increasing evidence supports the presence of sex and gender differences in neurodegenerative conditions, including Alzheimer's disease and Parkinson's disease. There is a critical need to more closely examine sex and gender differences in all stages of research, therapeutic development, and clinical treatment to enable better outcomes through precision medicine approaches. This episode focuses on the relevance of sex and gender factors in Parkinson's disease and efforts to transform scientific research, policy, and healthcare to identify and address needs based on sex and gender. Our guest Dr. Antonella Santuccione Chadha discusses her work with the Women’s Brain Project, their recent roundtable on enhancing care in Parkinson’s disease, and the organization's goals for the future. Antonella is a medical doctor with experience spanning positions in clinical care, academic research, the Swiss Agency for Therapeutic Products (regulatory), and industry leadership and consultation for large pharmaceutical companies and smaller start-up companies. She is currently Co-Founder and Pro Bono Chief Executive Officer of the Women’s Brain Project, an international non-profit organization studying sex and gender determinants to brain and mental health.

Mentioned in this episode:

Understanding Genetics, Pathology, and Progression in Parkinson's Disease and Atypical Parkinsonian Syndromes with Huw Morris

Tue, 05 Mar 2024 03:00:00 -0400

Atypical Parkinsonian Syndromes, such as progressive supranuclear palsy (PSP), multiple system atrophy (MSA), corticobasal degeneration (CBD), and dementia with Lewy bodies are often initially diagnosed as Parkinson's disease. Incorrect, incomplete, or delayed diagnoses are barriers to beginning the most appropriate treatment early in the disease course. More research is needed to facilitate early diagnoses, understanding of disease pathogenesis, and monitoring of disease progression. However, largescale, collaborative initiatives are making meaningful progress in understanding genetic contributors to disease pathology and progression in Parkinson's disease. Our guest in this episode, Dr. Huw Morris, has spent more than twenty five years researching Parkinson's disease and parkinsonian syndromes, and he shares highlights from recent work, including studies on the genetics and pathogenesis of Parkinson’s disease and other parkinsonian syndromes. Huw is Professor of Clinical Neuroscience at University College London Institute of Neurology, as well as an Honorary Consultant Neurologist at the Royal Free Hospital and the National Hospital for Neurology and Neurosurgery Queen Square.

Mentioned in this episode:

Therapies for Tomorrow: How Better Clinical Trial Design Leads to Better Treatments (Webinar Audio)

Wed, 28 Feb 2024 12:00:00 -0400

The drug development pipeline is key to bringing new therapies to people with Parkinson’s disease (PD). With major breakthroughs in research in the past year, including a new biomarker for PD, The Michael J. Fox Foundation’s Parkinson’s Progression Markers Initiative (PPMI) study and other initiatives can be leveraged to create better designed trials. This audio from our Third Thursdays Webinar features a conversation about all the ways clinical trial design is changing, and why leaders in the space believe those changes will lead to better treatments. The webinar includes contributions from a person with PD, a researcher and an industry leader.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your network. https://apple.co/3p02Jw0

Whether you have Parkinson’s or not, you can help move research forward. Join the study that’s changing everything. Find out more at michaeljfox.org/podcast-ppmi.

Mentioned in this episode:

Examining the Proposed Biological Definition of Neuronal Alpha-Synuclein Disease and Staging System with Lana Chahine

Tue, 20 Feb 2024 03:00:00 -0400

For many years, Parkinson's disease and dementia with Lewy bodies have been defined using clinical features. With recent advances in biomarkers, particularly the alpha-synuclein seed amplification assay that allows us to detect misfolded and aggregated alpha-synuclein in cerebrospinal fluid, it is now possible to identify the presence of pathological neuronal alpha-synuclein in living patients. With input from diverse stakeholders, a new biological definition of neuronal alpha-synuclein disease (NSD) has been proposed, along with an integrated staging system (NSD-ISS). In this interview, we discuss the development of this biologic definition for Parkinson’s disease and the staging system with Dr. Lana Chanine, one of the lead authors of the recently published manuscript in The Lancet Neurology that describes this work. It is important to note that the NSD and NSD-ISS are for research purposes only right now, and they are not ready to be implemented in the clinic. Lana is a Movement Disorders Neurologist and Associate Professor of Neurology at the University of Pittsburgh.

Mentioned in this episode:

Dating and New Relationships after a Parkinson’s Diagnosis

Wed, 14 Feb 2024 12:00:00 -0400

Dating and beginning new relationships with Parkinson’s involve distinct challenges, joys and fears. In this frank and funny podcast, our experts discuss how they face considerations like building and maintaining confidence, disease disclosure, and the importance of self-knowledge and self-care in new relationships. They remind us all that no matter what we’re facing, dating and finding love can be fun and fulfilling.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your network. https://apple.co/3p02Jw0  

Mentioned in this episode:

Managing Risk for Drug Discovery and Development in Parkinson's Disease with Kalpana Merchant

Tue, 06 Feb 2024 03:00:00 -0400

There is a pressing need to develop safe and effective disease-modifying and symptomatic treatments for Parkinson's disease. Through improvements in our understanding of the pathophysiology of the disease, as well as genetic risk factors, new potential treatment targets have emerged. However, bringing a promising new compound from the lab through all of the steps of drug development is a long, difficult, and resource-intensive process. In recent years, collaborative efforts and advances in biomarkers have led to important breakthroughs that have the potential to facilitate the development of new drugs for Parkinson's disease. In this episode, Dr. Kalpana Merchant draws from over two decades of pharmaceutical industry experience to share progress in drug discovery and development for Parkinson’s disease and other neurodegenerative conditions. Kalpana is President and Chief Scientific Officer at TransThera Consulting, which provides guidance on drug discovery and translational strategies to biopharma startup companies. She is also an Adjunct Professor at Northwestern University’s Feinberg School of Medicine, a member of the Oregon Innovation Council, a Scientific Advisor at The Michael J. Fox Foundation, and she serves on advisory panels at the National Institutes of Health.

Mentioned in this episode:

New Year, New Moves! Explore Exercise for Life with Parkinson’s (Webinar Audio)

Wed, 24 Jan 2024 12:00:00 -0400

We know exercise is important for people with Parkinson’s. Once you’ve decided to move more, what next? In this audio from our Third Thursdays Webinar, our experts discuss strategies for making exercise a meaningful part of your life. They present ways to make time for exercise and to make the most of it, including being aware of different types, frequencies and intensities. This discussion will help you find a way to get moving and stay motivated.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your network. https://apple.co/3p02Jw0 

Join a Foundation-hosted run/walk event. Or register for the Unity Walk. Every mile moves us one step closer to a cure for Parkinson's. Learn more at michaeljfox.org.

Whether you have Parkinson’s or not, you can help move research forward. Join the study that’s changing everything. Find out more at michaeljfox.org/podcast-ppmi.

Mentioned in this episode:

How MJFF “De-Risks” PD Drug Development Pipeline

Wed, 17 Jan 2024 12:00:00 -0400

One key pillar of The Michael J. Fox Foundation’s research strategy is a focus on “de-risking" potential treatments for Parkinson’s disease. This episode of our award-winning “Parkinson’s Science POV” series explains how lowering the risk associated with developing new therapies leads to a more robust pipeline of treatments. The episode details several recent successes of the strategy.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your network. https://apple.co/3p02Jw0

Join a study today to help speed progress toward better treatments and a cure for Parkinson’s disease. To search for studies in your area, visit Fox Trial Finder at foxtrialfinder.org.

Whether you have Parkinson’s or not, you can help move research forward. Join the study that’s changing everything. Find out more at michaeljfox.org/podcast-ppmi.

Mentioned in this episode:

Using Neuroimaging and Biomarkers to Improve Neurodegenerative Disease Diagnosis and Assessment with John Seibyl

Tue, 16 Jan 2024 03:00:00 -0400

In neurodegenerative conditions such as Parkinson's disease (PD), patients often do not receive a diagnosis until the hallmark motor symptoms begin to manifest. This can be a decade or more after substantial changes start occurring in the brain. A major goal of the PD research field has been to develop methods for earlier detection and intervention. Over the years, there have been substantial advances in neuroimaging techniques and biological biomarkers that have allowed us to more accurately identify patients with Parkinson's disease, including the recent development of the alpha-synuclein seed amplification assay. In this episode, Dr. John Seibyl discusses his early work on neuroimaging in Parkinson's disease through to the groundbreaking, large-scale clinical trials he is involved with for assessing the impacts of neuroprotective drugs for Parkinson's disease as well as Alzheimer's disease. He also shares his perspectives as a researcher and a patient with Parkinson's disease. John is Chairman of the Board, Co-Founder, and Senior Scientist of the Institute for Neurodegenerative Disorders in New Haven, Connecticut. He is also a board-certified physician in both Psychiatry and Nuclear Medicine, and he is an Adjunct faculty member in Neurology at Yale University School of Medicine.

Mentioned in this episode:

Tools for Diagnosing and Visualizing Parkinson’s Disease (Webinar Audio)

Wed, 03 Jan 2024 12:00:00 -0400

Doctors have been using DaTscan brain imaging as a tool to help diagnose the Parkinson’s disease (PD) for more than a decade, but even people who know a lot about the disease often still have questions about its role — and the role of other imaging tools — in diagnosis and care. What’s a DaTscan, and how does it relate to PET, SPECT and MRI? When is a DaTscan or other brain imaging tool used in PD? Are there any risks?

In this audio from our Third Thursdays Webinar, experts and people with PD offer listeners an impromptu course in Brain Imaging 101. You’ll learn to differentiate the different types of imaging used to visualize the brain and how they are used in PD research and care. You’ll also learn the latest in efforts to visualize alpha-synuclein, the protein that misfolds and clumps in Parkinson’s, and what its selective imaging in the living brain will mean for PD clinical trials and care.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your network. https://apple.co/3p02Jw0 

Whether you have Parkinson’s or not, you can help move research forward. Join the study that’s changing everything. Find out more at michaeljfox.org/podcast-ppmi.

Mentioned in this episode:

Impacts and Goals of the Global Parkinson's Genetics Program with Christine Klein

Tue, 02 Jan 2024 03:00:00 -0400

A substantial portion of people with Parkinson's disease (PD) have a family history of the disease, and new findings continue to improve our understanding of relevant genetic variants. These discoveries are key for clarifying the mechanisms that lead to Parkinson's disease as well as the development of new therapies. The Global Parkinson's Genetics Program (GP2) was established to gather and integrate genetic and clinical data from diverse participants around the world to expand our knowledge of the genetic architecture of PD. In this episode, Dr. Christine Klein discusses her experiences as Co-Leader of the Monogenetic Network of GP2, including the early days of setting up this large-scale collaboration, important achievements to date, and priorities and considerations going forward. She also shares recent findings from her own research on genetic variants related to Parkinson's disease. Christine is Director of the Institute of Neurogenetics and of the Section of Clinical and Molecular Neurogenetics at the Department of Neurology, as well as the Schilling Professor of Neurology at the University of Lübeck in Germany. She is also Co-Director of the Monogenetic Network of GP2.

Mentioned in this episode:

Having Happy Holidays with Parkinson’s

Wed, 20 Dec 2023 12:00:00 -0400

The holidays can be a time of joyful celebration with those we love. They may also come with the stress of travel, disruptions to your regular routine or even loneliness. For those living with Parkinson’s disease (PD), or those taking care of someone they love with the disease, these feelings can be intensified. This podcast offers tips to people living with PD, as well as their care partners, friends and family, for how to prepare — mind, body and suitcase — to make your holidays happy. 

Like our podcasts? Please consider leaving a rating or review and sharing the series with your network. https://apple.co/3p02Jw0  

Whether you have Parkinson’s or not, you can help move research forward. Join the study that’s changing everything. Find out more at michaeljfox.org/podcast-ppmi.

Mentioned in this episode:

The Role of Inflammation and Immune Responses in Neurodegeneration with Malú Gámez Tansey

Tue, 19 Dec 2023 03:00:00 -0400

A growing body of evidence is expanding our understanding of the links between inflammation, our immune responses, brain health, and neurodegeneration. In particular, several genes associated with Parkinson's (including LRRK2) are known to be involved in inflammation, and peripheral inflammation has been shown to influence brain function and contribute to the development of neurodegenerative diseases. Better understanding the roles of inflammation and our immune responses in Parkinson's disease is important for developing new treatments and strategies to slow or prevent disease progression. In this episode, Dr. Malú Gámez Tansey talks about her research at the intersection of immunology, neuroscience, and genetics. She describes new findings and current projects in her lab, discusses advances in neuroimmunology, and shares her insights on important areas of opportunity in the field. Malú is the Norman and Susan Fixel Chair in Parkinson's Disease, Professor of Neuroscience and Neurology, and Director of the Parkinson's Foundation Research Center of Excellence at the University of Florida College of Medicine. She's also editor-in-chief of Nature Partner Journal Parkinson's Disease.

Mentioned in this episode:

Elucidating the Pathobiology of LRRK2 in Parkinson's Disease with Dario Alessi

Tue, 05 Dec 2023 03:00:00 -0400

Mutations in the LRRK2 gene were first linked to Parkinson's disease (PD) risk in 2004. Since then, researchers from around the world have advanced our understanding of the mechanisms through which LRRK2 may contribute to PD, leading to the development of three potential LRRK2-targeted therapies that are now being evaluated in clinical trials. Along with colleagues and collaborators, Dr. Dario Alessi has pioneered new research and approaches that have aided in the development of drugs to inhibit LRRK2 and potentially treat people with Parkinson's disease. In this episode Dario discusses his work developing the LRRK2 kinase assay, LRRK2 Ser935 dephosphorylation assay, and Rab phosphorylation assay, as well as future directions and opportunities in the field. This year, Dario received the 2023 Robert A. Pritzker Prize for Leadership in Parkinson’s Research for his substantial research contribution and his commitment to mentoring the next generation of Parkinson’s scientists. Dario is the Professor of Signal Transduction and Science Director of the Medical Research Council Protein Phosphorylation and Ubiquitylation Unit at the University of Dundee.

Mentioned in this episode:

A Year Like No Other in Parkinson’s Research: 2023 in Review (Webinar Audio)

Wed, 29 Nov 2023 11:00:00 -0400

In a year of remarkable progress for the Parkinson’s field, we’re entering a new era for better understanding the biology of the disease, with the identification of a breakthrough biomarker accelerating new therapeutics through the clinical pipeline and legislators on Capitol Hill moving toward legislation that unites the federal government on a mission to treat, prevent and cure Parkinson’s disease.

What does this progress mean for researchers studying Parkinson’s and for those living with the disease? And what will come next?

Tune in as scientists and staff from The Michael J. Fox Foundation (MJFF) answer these questions and share insights in our latest Third Thursdays Webinar.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your network. https://apple.co/3p02Jw0 

Join a study today to help speed progress toward better treatments and a cure for Parkinson’s disease. To search for studies in your area, visit Fox Trial Finder at foxtrialfinder.org.

Whether you have Parkinson’s or not, you can help move research forward. Join the study that’s changing everything. Find out more at michaeljfox.org/podcast-ppmi.

Mentioned in this episode:

New Frontiers in Deep Brain Stimulation Research for Parkinson’s disease with Michael Okun

Tue, 21 Nov 2023 03:00:00 -0400

For decades, researchers, clinicians, and industry professionals have continued to study and optimize deep brain stimulation (DBS) with the goal of providing the best possible personalized treatment for Parkinson’s disease (PD) and other neurological conditions. In this episode, Dr. Michael Okun joins us to discuss his research and some of the recent advances in deep brain stimulation and other areas. He draws from his extensive research and clinical experience applying DBS and neuromodulation therapies for patients with PD, Tourette syndrome, tic disorders, dystonia, essential tremor, and obsessive-compulsive disorder. Michael is co-founder and co-director of the Norman Fixel Institute for Neurological Diseases at the University of Florida, as well as Medical Advisor for the Parkinson’s Foundation. He is a board-certified neurologist, movement disorders specialist, neuroscientist, author, and an expert on deep brain stimulation and neuromodulation for movement disorders.

Mentioned in this episode:

Genetics Discovery Underscores Importance of Diversity in Parkinson’s Disease Research

Wed, 15 Nov 2023 12:30:00 -0400

In a groundbreaking discovery earlier this year, a global consortium found a new variant in the GBA gene that is associated with a higher risk of Parkinson’s disease (PD) for people of African ancestry. The finding marks the first African ancestry-specific genetic risk factor for Parkinson’s disease. In this podcast, researchers share the human stories behind the discovery, which underscores the importance of international collaboration and the participation of underrepresented communities in research.

Themes covered in this discussion:

(02:05) – Breaking down the genetic discovery and why it’s important for PD research
(05:27) – More on the genetic samples that resulted in this discovery
(06:53) –Why the GBA1 gene is of interest and its connection to PD
(11:13) – How the Global Parkinson’s Genetics Program (GP2) maintains privacy and confidentiality of data from study participants
(13:15) – How people should think about genetics as a risk factor for PD
(14:55) – Capacity building and building community trust
(19:57) –Why this discovery takes us closer to finding better treatments and a cure for PD
(21:51) – Story behind accidental discovery of GBA1 variant
(22:50) – Background on GP2 and excitement on the GBA1 variant discovery
(33:17) – Ethnicity and health risk factors and other determinants of health
(35:03) – Importance of diversity, equity and inclusion in science and to The Michael J. Fox Foundation’s mission
(36:52) – Research in PD historically focused on people of Northern European ancestry
(38:09) –Why people from underrepresented groups need to lead these studies
(39:30) – Importance of including underrepresented populations across the research pipeline
(40:18) –Why research participation is important and how you can get involved

Like our podcasts? Please consider leaving a rating or review and sharing the series with your network. https://apple.co/3p02Jw0 

Whether you have Parkinson’s or not, you can help move research forward. Join the study that’s changing everything. Find out more at michaeljfox.org/podcast-ppmi

Mentioned in this episode:

Understanding Sleep Differences in Parkinson’s Disease with Dr. Amy Amara

Tue, 07 Nov 2023 03:00:00 -0400

Sleep impacts our lives in many different ways, and Dr. Amy Amara joins us in this episode to discuss her career and findings from her research on sleep in Parkinson’s disease (PD). She shares her insights on the characteristics of sleep in people with Parkinson’s disease, how sleep can be impacted by exercise, medications, and deep brain stimulation, and how studying rapid eye movement (REM) sleep behavior disorder may be important for developing early treatments before PD motor symptoms manifest. Amy is a Professor of Neurology at CU Anschutz School of Medicine who is an expert on quantitative electroencephalography, sleep disorders, and neurodegenerative disease.

This podcast is geared toward researchers and clinicians. If you live with Parkinson’s or have a friend or family member with PD, listen to The Michael J. Fox Foundation Parkinson’s Podcast. Hear from scientists, doctors and people with Parkinson's on different aspects of life with the disease as well as research toward treatment breakthroughs at https://www.michaeljfox.org/podcasts.

Mentioned in this episode:

Ask Us Anything: Answers to Your Questions about Gut Health and Parkinson’s (Webinar Audio)

Wed, 01 Nov 2023 11:00:00 -0400

People with Parkinson’s disease (PD) have lots of questions about probiotics, prebiotics, laxatives and fiber. That’s because constipation and bloating are some of the more bothersome but less talked about symptoms of PD. In this audio from our Third Thursdays Webinar, experts and people with PD discuss effective ways for managing constipation and other gut-related symptoms. You’ll also learn about emerging treatments for constipation, the gut-brain connection and why the gut is linked to Parkinson’s.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your network. https://apple.co/3p02Jw0 

Whether you have Parkinson’s or not, you can help move research forward. Join the study that’s changing everything. Find out more at michaeljfox.org/podcast-ppmi.

Mentioned in this episode:

Industry Contributions and Collaborations in Parkinson's Research with Karoly Nikolich

Tue, 17 Oct 2023 03:00:00 -0400

In this episode, serial entrepreneur Dr. Karoly Nikolich shares his perspectives on the industry side of the state of neuroscience, as well as areas of opportunity and the role of industry in advancing the field. He also discusses recent major breakthroughs, the importance of industry partnerships, including collaborations with The Michael J. Fox Foundation (MJFF), and how he is working to advance Parkinson's disease research through his work at Alkahest and other endeavors. Karoly is a scientific advisor at Bayshore Global Management and at Pivotal Bioventures. In addition, he is Chairman and Executive Advisor at Alkahest Inc., and also an Adjunct Professor of Psychiatry at Stanford University. Karoly has extensive expertise in the biotech and neuro-therapeutics industries, and he also manages his foundation, the Scholar Nikolich Foundation.

Mentioned in this episode:

The Parkinson's Research Landscape and the Role of MJFF with Brian Fiske and Mark Frasier

Thu, 12 Oct 2023 03:00:00 -0400

New research advances are expanding our knowledge of Parkinson's disease and bringing us closer to the ultimate goals of new treatments, effective cures, and disease prevention. In this introductory episode, you'll hear from Dr. Brian Fiske and Dr. Mark Frasier, Co-Chief Scientific Officers at The Michael J. Fox Foundation for Parkinson's Research (MJFF). During the conversation, they provide their perspectives on the state of the field of Parkinson's disease research, describe new advances in biomarkers for Parkinson's disease, and discuss progress in the development of novel therapeutics. They also share insights on resources and tools being developed to advance Parkinson's research, MJFF's research strategy, and what it could mean for your research.

Mentioned in this episode:

Finding Your Way: Working through Emotions in Early Years with Parkinson’s (Webinar Replay)

Wed, 27 Sep 2023 12:00:00 -0400

Shock, doubt, anxiety — a diagnosis of Parkinson’s can trigger these and many other difficult emotions. This replay of audio from our Third Thursdays Webinar features a conversation among people with Parkinson’s about how they processed the emotional aftermath and navigated the early years following their diagnosis. We also hear from a psychologist who specializes in Parkinson’s about what she’s learned about how people deal with this life-changing diagnosis and ways to manage the emotions in a positive way.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your network. https://apple.co/3p02Jw0 

Whether you have Parkinson’s or not, you can help move research forward. Join the study that’s changing everything. Find out more at michaeljfox.org/podcast-ppmi.

Mentioned in this episode:

Too Much or Not Enough: Dyskinesia and “Off” Time in Parkinson's (Webinar Replay)

Wed, 23 Aug 2023 12:00:00 -0400

In this replay of audio from our Third Thursdays Webinar, Michael J. Fox Foundation Patient Council member Larry Gifford leads a discussion on common Parkinson’s issues — dyskinesia and "off" time — and how to treat them.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your network. https://apple.co/3p02Jw0 

Whether you have Parkinson’s or not, you can help move research forward. Join the study that’s changing everything. Find out more at michaeljfox.org/podcast-ppmi.

Mentioned in this episode:

Reporting on Stem Cells for Parkinson’s

Wed, 16 Aug 2023 12:00:00 -0400

Stem cells have grabbed headlines for decades. Now, at last, they are starting to deliver on their therapeutic promise, with multiple stem cell therapies in clinical trials for Parkinson’s disease. This episode of our award-winning “Parkinson’s Science POV” series brings us up to date on these trials, including how scientists are using stem cells to replace dopamine, the chemical that’s lost in Parkinson's disease.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your network. https://apple.co/3p02Jw0 

Join a study today to help speed progress toward better treatments and a cure for Parkinson’s disease. To search for studies in your area, visit Fox Trial Finder at foxtrialfinder.org.

Whether you have Parkinson’s or not, you can help move research forward. Join the study that’s changing everything. Find out more at michaeljfox.com/podcast-ppmi.

Mentioned in this episode:

Digestible Tips: Your Gut and Parkinson’s

Wed, 12 Jul 2023 12:00:00 -0400

How’s this for a dinnertime conversation starter… did you know that what happens in your gut can have an impact on your brain health? Some experts even call the gut “the second brain” because of its huge community of microbes and large nerve network that links the gut to brain disease, like Parkinson’s.

Join our panel of experts who cover the latest research on this link between gut and brain health. And tune in as they discuss common gut symptoms of Parkinson’s and what you can do to manage them.

For more on this topic, visit michaeljfox.org/guthealth.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your network. https://apple.co/3p02Jw0

Mentioned in this episode:

From Low Blood Pressure to Bladder Problems: A Look at Lesser-Known Parkinson’s Symptoms (Webinar Replay)

Wed, 21 Jun 2023 12:00:00 -0400

Many people with Parkinson’s experience autonomic symptoms, like bladder problems, low blood pressure and constipation that can be hard to talk about. In this audio from our Third Thursdays Webinar replay, experts and patients open a dialogue on these issues and share ways to treat them.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your network. https://apple.co/3p02Jw0 

Whether you have Parkinson’s or not, you can help move research forward. Join the study that’s changing everything. Find out more at michaeljfox.com/podcast-ppmi

Mentioned in this episode:

Ask MJFF Anything: Your Questions for Our Scientists

Wed, 14 Jun 2023 12:00:00 -0400

In the latest installment of our award-winning “Parkinson’s Science POV” series, MJFF’s Maggie Kuhl sits down with Mark Frasier and Brian Fiske, Chief Science Officers at MJFF, in an “Ask MJFF Anything” edition of our podcast. These experts cover a variety of questions from our community about Parkinson’s disease (PD) therapies and treatments, the recent biomarker breakthrough and more. Get answers on topics ranging from how exercise helps improve balance, to what the new biomarker breakthrough means for the Parkinson’s community.

Whether you have Parkinson’s or not, you can help move research forward. Join the study that’s changing everything. Find out more at michaeljfox.com/podcast-ppmi

Mentioned in this episode:

Get Moving: Exercising for a Healthy Brain (Webinar Audio)

Wed, 31 May 2023 12:00:00 -0400

Have you ever wondered what’s the best exercise for your brain? Listen as our expert panel breaks down approachable tips to add more movement into your day-to-day, Parkinson’s-friendly exercises to try right now and the science behind the benefits of working up a sweat.

Join hundreds of Parkinson’s community members June 17 weekend for our annual Virtual Run/Walk. Register and learn more at www.michaeljfox.org/runwalk

Like our podcasts? Please consider leaving a rating or review and sharing the series with your network. https://apple.co/3p02Jw0

Mentioned in this episode:

If Not Us, Who? Humans behind a Biomarker Breakthrough

Wed, 24 May 2023 12:00:00 -0400

Faith and science are not often discussed together, but science requires a leap of faith. A few years ago, MJFF staff scientists, Samantha Hutten, PhD and Katie Kopil, PhD never would have guessed that a leap of faith and a cold call to a researcher in Texas would lead to a tool that, for the first time, can detect Parkinson’s in people who have not yet shown symptoms. With the help of the countless community members taking part in the PPMI study, these researchers found a biomarker for Parkinson’s. Hear all about the journey to the breakthrough and what it means to the Parkinson’s community in this rich discussion with some of the humans behind it.

Whether you have Parkinson’s or not, you can help move research forward. Join the study that’s changing everything. michaeljfox.org/podcast-ppmi

Like our podcasts? Please consider leaving a rating or review and sharing the series with your network. https://apple.co/3p02Jw0

Mentioned in this episode:

Major Research Breakthrough: A New Biomarker for Parkinson's (Webinar Audio)

Wed, 26 Apr 2023 12:00:00 -0400

In April, The Michael J. Fox Foundation (MJFF) announced a major biomarker breakthrough, opening a new chapter for Parkinson’s research — with the promise of better drug development and care for all people and families living with the disease. With the new test, validated by MJFF’s Parkinson’s Progression Markers Initiative (PPMI), researchers can objectively define and monitor this pathology for the first time in the living body. Experts explain the promise this research holds for all people living with Parkinson’s.

PPMI is enrolling people with and without Parkinson's disease. Join the study that's changing everything. michaeljfox.org/podcast-ppmi

Like our podcasts? Please consider leaving a rating or review and sharing the series with your network. https://apple.co/3p02Jw0

Mentioned in this episode:

Trouble Sleeping? What to Know about Acting Out Dreams and Other Sleep Issues (Webinar Replay)

Wed, 22 Mar 2023 12:00:00 -0400

Some people act out their dreams while asleep. They may punch, kick, yell or even fall out of bed. This sleep problem can be linked to Parkinson’s and other brain diseases. In this episode, experts share why sleep issues happen and what you can do to manage them.

If you or your bed partner have sleep issues — whether you have Parkinson’s or not — you can play a critical role in research. Join the study that's changing everything at michaeljfox.org/podcast-ppmi

More about The Michael J. Fox Foundation Parkinson’s Podcast:

Scientific, medical and patient experts on Parkinson’s discuss practical tips on living well with the disease, current research headlines and more in this award-winning podcast. Get involved today, and access free resources at michaeljfox.org. 

Like our podcasts? Please consider leaving a rating or review and sharing the series with your network. apple.co/3p02Jw0

Mentioned in this episode:

What You Need to Know about Sleep, Aging and Parkinson's

Wed, 15 Mar 2023 12:00:00 -0400

Did you know that RBD – REM sleep behavior disorder, or acting out dreams -- can be an early indicator of Parkinson’s? Many people develop sleep issues as they age — with and without PD.

Join host Larry Gifford in a rich discussion with expert Stephen Joza, MD, PhD; Allen Dance, recently diagnosed with RBD; and Richie Rothenberg, patient advisor to The Michael J. Fox Foundation (MJFF), with his care partner Julie Merson, on why sleep is important, strategies to tackle sleep problems and the importance of participating in research studies like MJFF’s Parkinson’s Progression Markers Initiative (PPMI).

The PPMI study is learning more about the connection between RBD and Parkinson’s to understand who gets the disease, who doesn’t and why. And those insights could lead to better treatments and cures. For more information on RBD, visit michaeljfox.org/dreams.

More about The Michael J. Fox Foundation Parkinson’s Podcast:

Scientific, medical and patient experts on Parkinson’s discuss practical tips on living well with the disease, current research headlines and more in this award-winning podcast.
Get involved today, and access free resources at michaeljfox.org.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your network. https://apple.co/3p02Jw0

Mentioned in this episode:

One Step at a Time: Managing Gait and Balance Issues in Parkinson's (Webinar Audio)

Wed, 22 Feb 2023 12:00:00 -0400

From freezing to shuffling and everything in between, gait and balance issues can impact people with Parkinson’s at all stages of their journey. In this episode, listen as experts discuss emerging research and tips for people and care partners to improve mobility, prevent falls and maintain independence day to day.

The Michael J. Fox Foundation’s landmark research study is focused on learning more about how Parkinson’s starts, changes over time and how to stop it. Study volunteers are urgently needed. Anyone over age 18 can enroll. Join the study that's changing everything at michaeljfox.org/podcast-ppmi

More about The Michael J. Fox Foundation Parkinson’s Podcast:

Scientific, medical and patient experts on Parkinson’s discuss practical tips on living well with the disease, current research headlines and more in this award-winning podcast.
Get involved today, and access free resources at michaeljfox.org.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your network. https://apple.co/3p02Jw0

Mentioned in this episode:

Food for Thought: Answering Your Questions on Diet, Brain Health and Parkinson's

Wed, 08 Feb 2023 12:00:00 -0400

For many, the word “diet” has negative associations: cutting out the foods you love, not enjoying what you eat or following strict rules about what you can or can’t eat. But diet is a way of life. And you can still boost brain health or manage Parkinson’s with your favorite family recipes, dinner out with friends and even the salty or sweet snacks you crave most. The Michael J. Fox Foundation’s Rachel Dolhun, MD, fellowship-trained movement disorder specialist, board-certified neurologist and lifestyle medicine physician, sits down with expert dietitians Paula Montagna and Vanessa Rissetto, and Parkinson’s community members, Denise and Bernard Coley, to answer your most-asked questions on healthy eating and nutrition.

Want to learn more on this topic? Download our new guide on diet and brain health at michaeljfox.org/dietguide.

And for more easy-to-make recipes from today’s episode, visit michaeljfox.org.

The Michael J. Fox Foundation’s landmark research study is focused on learning more about how Parkinson’s starts, changes over time and how to stop it. Study volunteers are urgently needed. Anyone over age 18 can enroll. Join the study that's changing everything at michaeljfox.org/podcast-ppmi

More about The Michael J. Fox Foundation Parkinson’s Podcast:

Scientific, medical and patient experts on Parkinson’s discuss practical tips on living well with the disease, current research headlines and more in this award-winning podcast.
Get involved today, and access free resources at michaeljfox.org.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your network. https://apple.co/3p02Jw0

Mentioned in this episode:

Eating to Boost Brain Health and Ease Symptoms (Webinar Audio)

Wed, 25 Jan 2023 12:00:00 -0400

What foods are best for you? Whether you have Parkinson’s disease, or are concerned you might develop it, food and nutrition play a critical role in brain health. Our expert panel of Parkinson’s physicians and nutritionists shares effective ways to manage symptoms through nutrition and mobility modifications to make food preparation and eating easier.

Learn more about diet and nutrition in our new free guide, available at michaeljfox.org/guides.

Our landmark research study, the Parkinson’s Progression Markers Initiative, is exploring the connection between smell loss and brain health. If you’re age 60 and up without Parkinson’s in the U.S. or Canada, request a free scratch-and-sniff test at mysmelltest.org/request.

More about The Michael J. Fox Foundation Parkinson’s Podcast:

Scientific, medical and patient experts on Parkinson’s discuss practical tips on living well with the disease, current research headlines and more in this award-winning podcast.
Get involved today, and access free resources at michaeljfox.org.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your network. https://apple.co/3p02Jw0

Mentioned in this episode:

Podcast: What Comes Next? Living with Parkinson’s Years after Diagnosis (Webinar Replay)

Wed, 21 Dec 2022 12:00:00 -0400

There are social, emotional and physical changes you may notice after living with Parkinson’s for some time. In this episode replay, experts discuss tips for managing symptoms, finding support and living well with Parkinson’s disease.

Our landmark Parkinson’s Progression Markers Initiative is open to anyone over age 18 in the U.S. Join the study that could change everything at michaeljfox.org/podcast-ppmi

Like our podcasts? Please consider leaving a rating or review and sharing the series with your network. https://apple.co/3p02Jw0

Mentioned in this episode:

Navegando el Viaje Emocional de un Diagnóstico de Parkinson (seminario virtual: grabación de audio)

Fri, 16 Dec 2022 12:00:00 -0400

Un diagnóstico de Parkinson puede traer muchas emociones diferentes: negación, ira, tristeza, frustración. Es importante saber que no importa qué emociones sientas, no estás solo. Escuche a los expertos, personas con Parkinson y un especialista en trastornos del movimiento, hablar sobre cómo navegar por las emociones y el viaje viviendo con la enfermedad. Este episodio es de nuestro último seminario virtual en español y ofrece reflexiones personales sobre los pasos que las personas y familiares con Parkinson pueden tomar para aceptar y vivir bien con la enfermedad.

Si prefiere escuchar sobre la marcha, suscríbase a nuestro podcast de Parkinson de la Fundación Michael J. Fox en iTunes o a través de cualquier aplicación de podcast en su celular inteligente o tableta. Si le gustó este podcast, compártelo con una amistad o deja una reseña en iTunes. Ayuda a oyentes como usted a encontrar y apoyar nuestra misión.

Mentioned in this episode:

2022 in Review: Progress Toward Better Treatments and Prevention (Webinar Audio)

Wed, 30 Nov 2022 12:00:00 -0400

The Parkinson’s community often asks, “What new treatments are in the pipeline?” In this episode, experts discuss the latest approaches in treating the spectrum of Parkinson’s, from early diagnosis to advancing disease. They also highlight the latest tools to predict and measure Parkinson’s and critical steps toward prevention.

Recently diagnosed with Parkinson’s? You can play a critical role in the Parkinson’s Progression Markers Initiative (PPMI) study. Learn more at michaeljfox.org/podcast-newlydiagnosed

Anyone over age 18 in the U.S. — with or without Parkinson’s, at any stage — can join the online part of PPMI. Get started at michaeljfox.org/podcast-ppmi

Like our podcasts? Please consider leaving a rating or review and sharing the series with your network. apple.co/3p02Jw0

Mentioned in this episode:

Podcast: Deep Brain Stimulation: Is It Right for Me or My Loved One? (Webinar Replay)

Wed, 26 Oct 2022 12:00:00 -0400

Many people and families with Parkinson’s wonder if deep brain stimulation (DBS) — a surgical procedure for Parkinson’s — is a possible treatment option for them. In this episode replay, experts discuss who should consider DBS; potential benefits and risks; and the latest advancements in DBS research.

If you’ve recently been diagnosed with Parkinson’s, you can play a critical role in our landmark Parkinson’s Progression Markers Initiative (PPMI) study. Get started at michaeljfox.org/podcast-newlydiagnosed

Anyone over age 18 in the U.S. — with Parkinson’s, at any stage, or without — can join the online part of PPMI at michaeljfox.org/podcast-ppmi

Like our podcasts? Please consider leaving a rating or review and sharing the series with your network. https://apple.co/3p02Jw0

Mentioned in this episode:

From Diagnosis On: My First Days with Parkinson’s

Wed, 28 Sep 2022 12:00:00 -0400

A Parkinson’s diagnosis can bring many different emotions — denial, anger, sadness, frustration. It’s important to know that no matter what emotions you feel, you’re not alone. Listen as people with Parkinson’s and their loved ones discuss how they’ve navigated emotions in the early years with Parkinson’s disease. This podcast episode offers personal reflections on steps people can take toward acceptance and real-world advice for those recently diagnosed and beyond.

If you’ve been diagnosed with Parkinson’s in the past two years, you can play a critical role in the Parkinson’s Progression Markers Initiative (PPMI) study. Learn more at michaeljfox.org/podcast-newlydiagnosed

The online part of PPMI is open to anyone over age 18 in the U.S. Join the study that could change everything at michaeljfox.org/podcast-ppmi

Like our podcasts? Please consider leaving a rating or review and sharing the series with your network. apple.co/3p02Jw0

Mentioned in this episode:

Podcast: Public Policy and You: How to Become a Parkinson’s Advocate (Webinar Audio)

Wed, 31 Aug 2022 12:00:00 -0400

Public policy plays an important role in speeding a cure for Parkinson’s. In this episode, experts discuss ways to become a Parkinson’s advocate and how you can reach out to your elected officials to help influence change on behalf of the Parkinson’s community. Experts also highlight the first-ever legislation solely dedicated to ending Parkinson’s disease.

Ask your Representative to support The National Plan to End Parkinson’s Act at michaeljfox.org/national-plan

Recently diagnosed with Parkinson’s? You can play a critical role in the Parkinson’s Progression Markers Initiative (PPMI) study. Learn more at michaeljfox.org/podcast-newlydiagnosed

The online part of PPMI is open to anyone over age 18 in the U.S. Join the study that could change everything at michaeljfox.org/podcast-ppmi

Like our podcasts? Please consider leaving a rating or review and sharing the series with your network. apple.co/3p02Jw0

Mentioned in this episode:

Podcast: Virtual Checkup: How Telehealth Brings Parkinson's Care to You (Webinar Audio)

Wed, 27 Jul 2022 12:00:00 -0400

Many people with Parkinson’s consider telehealth a useful tool for getting care. But for some, the technology or visit may be tough to navigate. In this episode, experts discuss how to make the most of a virtual visit with a doctor and the impact of telehealth on research and care.

Recently diagnosed with Parkinson’s? You can play a critical role in the Parkinson’s Progression Markers Initiative (PPMI) study. Connect with the PPMI team at michaeljfox.org/podcast-ppmi-sites

The online part of PPMI is open to anyone over age 18 in the U.S. Join the study that could change everything at michaeljfox.org/podcast-ppmi

Like our podcasts? Please consider leaving a rating or review and sharing the series with your network. apple.co/3p02Jw0

Mentioned in this episode:

Making Strides: Treatments and Technology for Walking Problems in Parkinson's

Wed, 20 Jul 2022 12:00:00 -0400

Walking is a complex skill. So, shares Catherine Kopil, PhD, in the third episode of our “Parkinson’s Science POV” podcast series.

Gait requires a symphony of connections between the brain and body, which makes it one of the hardest Parkinson’s symptoms to treat. Kopil, MJFF Senior Vice President of Clinical Research, and Chief Scientific Officer Mark Frasier, PhD, discuss progress toward understanding the neuroscience of gait challenges, such as walking, balancing, shuffling steps and freezing. They talk about treatments in testing and the use of digital technology to measure and predict gait changes in people with PD.

Much of this work is happening in our landmark Parkinson’s Progression Markers Initiative (PPMI) study. Join today at www.michaeljfox.org/podcast-PPMI to contribute to new discoveries and better measures of disease. PPMI especially needs people recently diagnosed with Parkinson’s or with certain risk factors such as smell loss or acting out dreams.

Anyone over the age of 18 in the United States can join through its online platform. Outside the U.S.? View a list of international recruiting sites at www.michaeljfox.org/ppmi-recruiting-sites.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your network. https://apple.co/3p02Jw0

Mentioned in this episode:

From Low Blood Pressure to Bladder Problems: A Look at Lesser-Known Parkinson’s Symptoms (Webinar)

Wed, 29 Jun 2022 12:00:00 -0400

Parkinson’s can affect the automatic and involuntary functions our bodies perform, like heartbeat and digestion. In this episode, experts discuss common but lesser-known Parkinson’s symptoms — including bladder problems, constipation, low blood pressure and sweating — and what you can do to treat them.

Recently diagnosed with Parkinson’s? You can play a critical role in the Parkinson’s Progression Markers Initiative (PPMI) study. Connect with the PPMI team at michaeljfox.org/podcast-ppmi-sites

The online part of PPMI is open to anyone over age 18 in the U.S. Join the study that could change everything at michaeljfox.org/podcast-ppmi

Like our podcasts? Please consider leaving a rating or review and sharing the series with your network. apple.co/3p02Jw0

Mentioned in this episode:

A Special Conversation in Honor of Father’s Day: Adult Children Reflect on Having a Father with Parkinson’s

Wed, 15 Jun 2022 12:00:00 -0400

In honor of Father’s Day, The Michael J. Fox Foundation (MJFF) is sharing a special podcast episode between three adult children who discuss how they each have navigated having a father with Parkinson’s disease.

This Father’s Day and beyond, MJFF celebrates the experiences of patients, loved ones, researchers, advocates and supporters — speeding progress toward a cure. The Foundation’s landmark study, the Parkinson’s Progression Markers Initiative (PPMI), is enrolling parents, brothers and sisters, and children (over age 60) of people with Parkinson’s. PPMI is open to anyone over age 18 in the U.S. Join the study that could change everything at michaeljfox.org/podcast-ppmi.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your network. apple.co/3p02Jw0

Mentioned in this episode:

What's in Your DNA? Understanding Parkinson's Genetics (Webinar)

Wed, 25 May 2022 12:00:00 -0400

What is the science behind genetic inheritance that increases the chance of getting Parkinson’s disease (PD) later in life? In this episode, experts explain what genetic mutations are, those that are mostly seen in people with PD and the benefits of genetic testing.

Join the study that could change everything at michaeljfox.org/podcast-ppmi.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your network. apple.co/3p02Jw0

Mentioned in this episode:

Your Elected Officials, Your Voice: Coming Together to Speed a Cure

Wed, 18 May 2022 12:00:00 -0400

Did you know the government plays an important role in helping find a cure for Parkinson’s, and in caring for those living with the disease? In this episode, Michael J. Fox Foundation policy experts and grassroots advocates discuss the importance of telling your story and building relationships with elected officials who represent you in the halls of power across the United States.

You can help lawmakers understand what matters to people with Parkinson’s. Join our policy network today at michaeljfox.org/advocacy

Like our podcasts? Please consider leaving a rating or review and sharing the series with your network. Apple.co/3p02Jw0

Mentioned in this episode:

Podcast: New to Parkinson’s? Steps to Take Today (Webinar Replay)

Wed, 27 Apr 2022 12:00:00 -0400

Navigating a Parkinson’s diagnosis can be challenging, but you’re not alone. In this episode replay, experts share practical tips for managing the early years of Parkinson’s disease.

If you’ve recently been diagnosed with Parkinson’s, you can play a critical role in our landmark Parkinson’s Progression Markers Initiative (PPMI) study. Connect with the study team today at michaeljfox.org/podcast-ppmi-sites.

Anyone over age 18 in the U.S. — with Parkinson’s, at any stage, or without — can join the online part of PPMI. Get started at michaeljfox.org/podcast-ppmi.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your network. https://apple.co/3p02Jw0

Mentioned in this episode:

Testing, Testing – How Doctors and Scientists Detect Parkinson’s

Wed, 13 Apr 2022 12:00:00 -0400

How is Parkinson’s diagnosed? Tracked? Importantly, predicted? In the second episode of our “Parkinson’s Science POV” podcast series, MJFF Chief Scientific Officers discuss progress toward better tests for Parkinson’s disease, including a recent report of a brain scan of a key Parkinson’s protein. They discuss imaging, fluid measures and wearable devices and how these objective tools could speed new treatments and improve care.

Much of this work and findings stem from our landmark Parkinson’s Progression Markers Initiative (PPMI) study. Join today at https://michaeljfox.org/podcast-PPMI to contribute to new discoveries and better measures of disease. PPMI especially needs people recently diagnosed with Parkinson’s or with certain risk factors such as a relative with the disease, smell loss or acting out dreams. Anyone over the age of 18 in the United States can join through its online platform. Outside the U.S.? View a list of international recruiting sites at https://www.michaeljfox.org/ppmi-recruiting-sites.

Like our podcasts? Please consider leaving a rating or review and sharing the series with your network. https://apple.co/3p02Jw0

Mentioned in this episode:

Parkinson’s Disease and Acting Out Your Dreams (Ask the MD Podcast)

Wed, 30 Mar 2022 12:00:00 -0400

We all dream when we sleep. Some don’t remember dreams. Others clearly recall what they did, how they felt, and who else was there. Still others unintentionally act out their dreams. They may imagine catching a touchdown pass, running from a wild animal, or fending off an enemy. In this episode, our on-staff movement disorder specialist speaks with a couple about their experience with acting out dreams, called REM sleep behavior disorder.

If you or your bed partner act out your dreams — whether you have Parkinson’s or not — you can play a critical role in research. Join the study that could change everything at michaeljfox.org/podcast-ppmi

Like our podcasts? Please consider leaving a rating or review and sharing the series with your network. apple.co/3p02Jw0

Mentioned in this episode:

Parkinson’s Pillow Talk: An Open Conversation on Sex, Sleep and Intimacy

Wed, 16 Feb 2022 12:00:00 -0400

Sexual problems are common in people with Parkinson's, but they can be difficult to talk about. In this episode, experts discuss how Parkinson’s and associated symptoms like sleep changes impact relationships and they share strategies for improving physical and emotional intimacy.

A deeper understanding of Parkinson’s disease biology could improve every available treatment. You can help us achieve that. Our landmark Parkinson’s Progression Markers Initiative is open to anyone over age 18 in the U.S. Join the study that could change everything at michaeljfox.org/podcast-ppmi

Like our podcasts? Please consider leaving a rating or review and sharing the series with your network. apple.co/3p02Jw0

Mentioned in this episode:

Diet, Exercise and Other Strategies for Living Well as You Age (Webinar)

Wed, 02 Feb 2022 12:00:00 -0400

People with Parkinson's often ask how diet and exercise fit into their overall care plan. In this episode, experts share what you can do today to eat healthier, exercise, boost brain health and live well as you age.

Our landmark Parkinson’s Progression Markers Initiative is open to anyone over age 18 in the U.S. Join the study that could change everything at michaeljfox.org/podcast-ppmi

Like our podcasts? Please consider leaving a rating or review and sharing the series with your network. apple.co/3p02Jw0

Mentioned in this episode:

Three Reasons to Be Optimistic about Parkinson’s Therapies for All Stages of Disease

Wed, 26 Jan 2022 12:00:00 -0400

Parkinson’s disease changes: its biology and symptoms start even before the cardinal movement issues and evolve decades after diagnosis. In the first episode of our new podcast series “Parkinson’s Science POV,” MJFF Chief Scientific Officers discuss strategies to stop disease progression at every stage. This episode covers our Foundation’s approach to preventing cognitive changes and falls and to moving toward a world where no one receives a diagnosis of Parkinson’s disease.

You can play a part in research, too. Our landmark Parkinson’s Progression Markers Initiative is open to anyone over age 18 in the U.S. Join the study that could change everything at michaeljfox.org/podcast-ppmi

Like our podcasts? Please consider leaving a rating or review and sharing the series with your network. https://apple.co/3p02Jw0

Mentioned in this episode:

PPMI: The Study that Could Change Everything (Webinar)

Wed, 29 Dec 2021 12:00:00 -0400

Over the past decade, The Michael J. Fox Foundation’s landmark Parkinson’s Progression Markers Initiative has changed how research is done and what scientists know about the brain. Listen as experts discuss the study’s expansion and why now it needs you.

PPMI is open to anyone over age 18 in the U.S. Join the study that could change everything at michaeljfox.org/podcast-ppmi

Mentioned in this episode:

Recently Diagnosed with Parkinson’s? Why Your Participation in Research Could Speed a Cure

Wed, 22 Dec 2021 12:00:00 -0400

People early in their disease course are valuable partners in research working toward cures. Experts discuss why this is so important for The Michael J. Fox Foundation’s landmark Parkinson’s Progression Markers Initiative (PPMI) and the critical role you can play in research.

Recently diagnosed with Parkinson’s? Connect with the PPMI team today at michaeljfox.org/podcast-ppmi-sites

PPMI is open to anyone over age 18 in the U.S. Join the study that could change everything at michaeljfox.org/podcast-ppmi

Like our podcasts? Please consider leaving a rating or review and sharing the series with your network. https://apple.co/3p02Jw0

Mentioned in this episode:

Podcast: Steps Closer to Stopping Parkinson's: 2021 Research Review (Webinar)

Wed, 24 Nov 2021 12:00:00 -0400

Hear expert panelists discuss the latest advancements in Parkinson’s research for our 2021 research review webinar.

Mentioned in this episode:

“Progress on the Path to the Cure” Research Roundtable Recap

Wed, 17 Nov 2021 12:00:00 -0400

In this podcast, we recap the discussion from our Research Roundtable's expert panel of scientists, program leaders and a person with Parkinson’s.

Mentioned in this episode:

Podcast: Too Much or Not Enough: Dyskinesia and "Off" Time in Parkinson's (Webinar)

Wed, 13 Oct 2021 12:00:00 -0400

Hear our panelists discuss common Parkinson’s issues — "off" time and dyskinesia — and how to treat them.

Mentioned in this episode:

Parkinson’s “Off” Time: What It Looks Like, and How to Manage It

Wed, 22 Sep 2021 12:00:00 -0400

What is an “off” period in Parkinson’s? Why does it look so different from person to person? And how do you manage these episodes? Experts discuss steps to work with your doctor and care partners to manage these times when medication is wearing off between doses.

Mentioned in this episode:

Podcast: Do You Love Someone Who Has Parkinson’s? (Webinar)

Fri, 10 Sep 2021 12:00:00 -0400

Hear our panelists discuss life with Parkinson’s from a loved one’s perspective.

Mentioned in this episode:

The PD Avengers Podcast Takeover: Meet Global Parkinson’s Organizations and How They Can Help You (Part 2)

Wed, 01 Sep 2021 12:00:00 -0400

Tune in to part two of this podcast takeover as the global advocacy group — the PD Avengers — highlights more Parkinson’s organizations from all over the world. Connect with new groups, learn about their mission and find resources that can support you and your family in your journey with the disease.

Mentioned in this episode:

The PD Avengers Podcast Takeover: Meet Global Parkinson’s Organizations and How They Can Help You (Part 1)

Wed, 25 Aug 2021 12:00:00 -0400

Ever wondered why there are so many Parkinson’s organizations around the world? Join the PD Avengers — a global advocacy group — as they take over MJFF’s podcast to understand what sets each organization apart, and how you can get involved today.

Mentioned in this episode:

Podcast: What Comes Next? Living with Parkinson’s Years after Diagnosis (Webinar)

Wed, 21 Jul 2021 12:00:00 -0400

A brief summary of this episode

Mentioned in this episode:

Podcast: Deep Brain Stimulation: Is It Right for Me or My Loved One? (Webinar)

Wed, 23 Jun 2021 12:00:00 -0400

Hear expert panelists discuss who should consider deep brain stimulation, a surgical procedure for Parkinson’s.

Mentioned in this episode:

Will You Be My Buddy? Finding Mentors, Friends and Parkinson's Support

Wed, 16 Jun 2021 12:00:00 -0400

Learn about how you can join the Foundation’s new online community — the Parkinson’s Buddy Network — to build meaningful connections with other people and families navigating the disease.

Mentioned in this episode:

Podcast: You’re Not Alone: Tips for Building Connections in the Parkinson’s Community (Webinar)

Wed, 26 May 2021 12:00:00 -0400

Hear expert panelists offer ways to manage isolation and loneliness and tips for creating meaningful community connections.

Mentioned in this episode:

Podcast: Volunteering for Parkinson’s Research: What to Know and Expect (Webinar)

Wed, 28 Apr 2021 12:00:00 -0400

Hear our expert panelists discuss the benefits and risks of participating in Parkinson’s research.

Mentioned in this episode:

Myths about Levodopa (Ask the MD Podcast)

Wed, 31 Mar 2021 12:00:00 -0400

Hear from our on-staff movement disorder specialist about the latest in Parkinson’s care and research.

Mentioned in this episode:

Podcast: Brain Boost: A Conversation on Thinking, Memory and Parkinson’s (Webinar)

Wed, 24 Mar 2021 12:00:00 -0400

Hear our expert panelists discuss thinking and memory changes that can happen in Parkinson’s.

Mentioned in this episode:

Podcast: New to Parkinson’s? Steps to Take Today (Webinar)

Wed, 24 Feb 2021 12:00:00 -0400

Hear our expert panelists offer practical tips for navigating a new Parkinson’s diagnosis.

Mentioned in this episode:

Experts Discuss: Thinking and Memory, Parkinson's and a Pandemic

Wed, 17 Feb 2021 12:00:00 -0400

Our experts share information, strategies and tips for living with or caring for someone with mild thinking and memory changes.

Mentioned in this episode:

Podcast: Night Fight with Parkinson’s: Acting Out Dreams, Insomnia and Other Sleep Issues (Webinar)

Wed, 27 Jan 2021 12:00:00 -0400

Hear our expert panelists offer practical tips and strategies for managing sleep issues in Parkinson’s disease.

Mentioned in this episode:

Thinking about Cognitive Changes in Parkinson’s (Ask the MD Podcast)

Wed, 27 Jan 2021 12:00:00 -0400

Hear from our on-staff movement disorder specialist about the latest in Parkinson’s care and research.

Mentioned in this episode:

Milestones and Momentum in Parkinson’s Research (Part 2)

Wed, 20 Jan 2021 12:00:00 -0400

Listen to part two of our conversation reviewing research highlights from the 20-year history of The Michael J. Fox Foundation. And learn about the next chapter the Foundation is just beginning to write.

Mentioned in this episode:

Podcast: Calling All Care Partners: Managing Disease and Burnout in 2020 (Webinar)

Tue, 22 Dec 2020 12:00:00 -0400

Hear our panelists offer practical tips and resources for caregiving in Parkinson’s.

Mentioned in this episode:

Milestones and Momentum in Parkinson’s Research (Part 1)

Wed, 09 Dec 2020 12:00:00 -0400

Tune in and walk down memory lane as Foundation leaders reflects on 20 years of milestones and momentum in Parkinson’s research.

Mentioned in this episode:

Podcast: What's Next for Parkinson's: Big Trials, New Treatments and Steps toward Prevention (Webinar)

Wed, 25 Nov 2020 12:00:00 -0400

Our panelists share the momentum happening in Parkinson’s research and what’s on the horizon in 2021.

Mentioned in this episode:

Visiting Loved Ones Who Have Parkinson’s during the Pandemic (Ask the MD Podcast)

Mon, 23 Nov 2020 12:00:00 -0400

Hear from our on-staff movement disorder specialist about the latest in Parkinson’s care and research.

Mentioned in this episode:

Coming Soon (Part 2): Previewing the Foundation’s Virtual Offerings for You and Your Family

Wed, 28 Oct 2020 12:00:00 -0400

Listen to the second part of our fall preview as Foundation staff recap recent events and look forward to what activities and offerings are right around the corner.

Mentioned in this episode:

Podcast: What to Watch This Election Season: A Roll Call of Parkinson’s Policy Priorities (Webinar)

Wed, 21 Oct 2020 12:00:00 -0400

This election season, we review what’s on the ballot and how these decisions impact the Parkinson’s community.

Mentioned in this episode:

Podcast: Pursuing a Game-changing Brain Scan for Parkinson's (Ask the PhD Video)

Wed, 14 Oct 2020 12:00:00 -0400

Michael J. Fox Foundation staff discuss brain scans for Parkinson’s.

Mentioned in this episode:

Podcast: Is Parkinson’s Inherited? (Webinar)

Wed, 23 Sep 2020 12:00:00 -0400

Listen to our panelists discuss what we know about Parkinson’s genetics and how genetic discoveries may lead to new treatments to stop or prevent disease.

Mentioned in this episode:

Podcast: New Technologies to Treat Parkinson’s (Ask the PhD Video)

Wed, 23 Sep 2020 12:00:00 -0400

Michael J. Fox Foundation staff discuss devices in testing to treat gait freezing and swallowing problems.

Mentioned in this episode:

In Conversation with MJFF Board Member Jeff Keefer — “Off” Time, New PD Drugs and Research (Ask the MD Podcast)

Wed, 23 Sep 2020 12:00:00 -0400

Hear from our on-staff movement disorder specialist and her guest, MJFF Board Member Jeff Keefer, diagnosed with Parkinson’s in 2007, about PD care and research.

Mentioned in this episode:

Coming Soon (Part 1): Previewing the Foundation’s Virtual Offerings for You and Your Family

Wed, 16 Sep 2020 12:00:00 -0400

In this episode of The Michael J. Fox Foundation Parkinson's Podcast, we roll out the “orange carpet” so to speak and give you a first look at the virtual activities, events and new resources the Foundation is putting together for the fall.

A virtual run/walk. A fireside chat with Michael J. Fox. And much, much more. Listen as our panelists give you an insider update on what’s coming down the pike and how you and your family can take part. Everyone here at the Foundation looks forward to connecting with the community this fall. Visit michaeljfox.org/here to learn more.

Rather listen on-the-go? Subscribe to our Michael J. Fox Foundation Parkinson's Podcast on iTunes or through any podcast app on your smartphone or tablet. And if you enjoyed what you heard, share it with a friend or leave a review on iTunes. It helps listeners like you find and support our mission.

Expert Panelists:

Host and person with Parkinson's Larry Gifford leads a discussion with:

Rachel Dolhun, MD, vice president of medical communications at MJFF and a board-certified movement disorder specialist
Holly Teichholtz, chief marketing officer at MJFF

Mentioned in this episode:

Exercise and Parkinson’s (Ask the MD Podcast)

Wed, 02 Sep 2020 12:00:00 -0400

Hear from our on-staff movement disorder specialist about the latest in Parkinson’s care and research.

Mentioned in this episode:

Podcast: Environment's Role in Parkinson’s Disease (Webinar)

Tue, 25 Aug 2020 12:00:00 -0400

Listen to our panelists discuss how environmental factors may lead to Parkinson’s and policies to limit those exposures.

Mentioned in this episode:

Inclusivity in Parkinson's Research and Care: Why It Matters in Speeding a Cure

Wed, 19 Aug 2020 12:00:00 -0400

In this episode of The Michael J. Fox Foundation Parkinson's Podcast, we explore the intersection of race and Parkinson’s in both the lived experience of obtaining care for the disease and how that translates to research.

Listen as our panelists have a candid conversation about the value of inclusivity to advance the field’s understanding of the disease and ultimately, more scientific breakthroughs. And learn about how the Foundation is working today to break down barriers to recruit and retain underrepresented communities to participate in research.

Rather listen on-the-go? Subscribe to our Michael J. Fox Foundation Parkinson's Podcast on iTunes or through any podcast app on your smartphone or tablet. And if you enjoyed what you heard, share it with a friend or leave a review on iTunes. It helps listeners like you find and support our mission.

EXPERT PANELISTS

Host and person with Parkinson’s Larry Gifford leads a discussion with:

Jonathan Jackson, PhD, founding director of Community Access, Recruitment, and Engagement (CARE) Research Center at Massachusetts General Hospital and principal investigator of the Fostering Inclusivity in Research Engagement for Underrepresented Populations in Parkinson’s Disease (FIRE-UP PD)

Bernadette Siddiqi, Associate Director of Research Partnerships at MJFF

María L. De León, MD, movement disorder specialist, MJFF Patient Council member and policy advocate

View a transcript of this podcast.

EXTRA READING:

Share Your Story -- The Michael J. Fox Foundation is seeking to grow its community by sharing diverse experiences and perspectives from all who are touched by Parkinson’s disease. If interested, please email your story to shareyourstory@michaeljfox.org along with the best contact information to reach you. We may share your story in future communications.

Get Involved in Research -- Learn more about Parkinson’s clinical research, who can participate and what types of studies are available. Download MJFF’s free guide to Navigating Clinical Trials, which is available in several languages, including Spanish.

Mentioned in this episode:

Why Your Advocacy Is Key to Advancing Parkinson's Priorities

Wed, 29 Jul 2020 12:00:00 -0400

In this episode of The Michael J. Fox Foundation Parkinson's Podcast, we discuss the importance of voicing your Parkinson’s priorities on Capitol Hill and how that might look different during a pandemic. Stepping into his new role as host of the podcast, Foundation Patient Council member Larry Gifford leads a conversation with Ted Thompson, JD, Senior Vice President of Public Policy at MJFF, and Israel Robledo, MJFF Patient Council member and policy advocate, about:

Why what happens in Washington, D.C. matters to people with Parkinson’s

Why grassroots advocacy is important and how members of Congress need to hear from constituents

How you can get involved today to advocate for COVID-19 related telemedicine and mental health policy asks that could impact our community

Interested in Parkinson’s advocacy? We need your help to take action. Sign up here.

Mentioned in this episode:

Podcast: The Pandemic and Parkinson’s: COVID-19 Impact on Disease, Care and Community (Webinar)

Wed, 22 Jul 2020 12:00:00 -0400

Listen to our panelists discuss results from our Fox Insight survey on the coronavirus and Parkinson's disease.

Mentioned in this episode:

Six Tips for Your First Year with Parkinson’s (and Beyond!) (Ask the MD Podcast)

Tue, 30 Jun 2020 12:00:00 -0400

Hear from our on-staff movement disorder specialist about the latest in Parkinson’s care and research.

Mentioned in this episode:

Podcast: Moving with Mood Changes in Parkinson’s: A Look at Depression and Anxiety in PD (Webinar)

Wed, 24 Jun 2020 12:00:00 -0400

Listen to our panelists discuss how depression and anxiety in Parkinson’s impacts life and care.

Mentioned in this episode:

COVID-19 Limited Series: Keeping Connected during the Pandemic When You Have Parkinson’s

Wed, 17 Jun 2020 12:00:00 -0400

Larry Gifford and guests explore ways to stay connected and ease anxiety while living with Parkinson’s in a time of uncertainty.

Mentioned in this episode:

COVID-19 Limited Series: Finding Positivity with Parkinson’s in a Pandemic

Wed, 03 Jun 2020 12:00:00 -0400

Larry Gifford and guests break down the importance of keeping a healthy mind and body after a Parkinson’s diagnosis and especially during COVID-19.

Mentioned in this episode:

COVID-19 Limited Series: The Pandemic and Parkinson’s Research

Wed, 20 May 2020 12:00:00 -0400

Larry Gifford and expert guests discuss how COVID-19 is affecting Parkinson’s research.

Mentioned in this episode:

COVID-19 Limited Series: The Pandemic and Your Parkinson’s Care

Wed, 06 May 2020 12:00:00 -0400

In our first episode, we dive into practical tips for managing your Parkinson’s during COVID-19. Michael J. Fox Foundation Patient Council member Larry Gifford leads a conversation with Rachel Dolhun, MD, a board-certified movement disorder specialist and Vice President of Medical Communications at MJFF, and, Katie Amodeo, a movement disorder specialist at the University of Rochester and a graduate of the Edmond J. Safra Fellowship in Movement Disorders, about:

Getting the most out of telemedicine
The impact of social distancing on those who need in-home care
DBS care
Managing stress and anxiety

Rather listen on-the-go? Subscribe to our Michael J. Fox Foundation Parkinson's Podcast on iTunes or through any podcast app on your smartphone or tablet.

Mentioned in this episode:

Podcast: Living in the Moment when the Moment Is Unprecedented (Webinar)

Wed, 22 Apr 2020 12:00:00 -0400

Listen to our panelists discuss ways to manage stress, anxiety and uncertainty.

Mentioned in this episode:

Information on Coronavirus for the Parkinson's Community (Webinar)

Wed, 25 Mar 2020 12:00:00 -0400

Listen to our panelists discuss how the coronavirus could impact people with Parkinson’s and actions you can take to manage new changes and challenges.

Mentioned in this episode:

Podcast: Love, Sex and Parkinson’s (Webinar)

Wed, 26 Feb 2020 12:00:00 -0400

Listen to our expert panelists discuss sexual changes women and men with Parkinson’s can experience.

Mentioned in this episode:

Pain and Parkinson’s (Ask the MD Podcast)

Wed, 19 Feb 2020 12:00:00 -0400

Hear from our on-staff movement disorder specialist about the latest in Parkinson’s care and research.

Mentioned in this episode:

Podcast: Eating Well with Parkinson’s Disease (Webinar)

Wed, 22 Jan 2020 12:00:00 -0400

Listen to our expert panelists discuss guidelines and considerations for a healthy diet with Parkinson’s.

Mentioned in this episode:

Podcast: Ask Us Anything: Our Doctors Take Your Questions (Webinar)

Thu, 02 Jan 2020 12:00:00 -0400

Listen to our on-staff movement disorder specialist and research leads answer your questions.

Mentioned in this episode:

Podcast: Being a Care Partner in Parkinson’s (Ask the MD Video)

Wed, 13 Nov 2019 12:00:00 -0400

Hear from our on-staff movement disorder specialist about the latest in Parkinson’s care and research.

Mentioned in this episode:

Podcast: Inflammation’s Role in Parkinson’s (Ask the PhD Video)

Thu, 24 Oct 2019 12:00:00 -0400

Foundation staff discuss how inflammation can be both bad and good and how studying its connection to Parkinson’s could help define, measure and treat disease.

Mentioned in this episode:

Podcast: Medical Marijuana and Other Alternative Therapies

Wed, 23 Oct 2019 12:00:00 -0400

Listen to our expert panelists talk about medical marijuana, and other complementary therapies, for Parkinson’s disease.

Mentioned in this episode:

Podcast: Medical Marijuana and Parkinson’s Disease

Wed, 16 Oct 2019 12:00:00 -0400

Hear from our on-staff movement disorder specialist about the latest in Parkinson’s care and research.

Mentioned in this episode:

Podcast: Thinking and Memory Problems in Parkinson’s

Wed, 25 Sep 2019 12:00:00 -0400

Listen to our expert panelists talk about cognitive changes in Parkinson’s, strategies to reduce them and research toward new therapies.

Mentioned in this episode:

Podcast: Update on Stem Cell Therapies for Parkinson’s Disease

Wed, 28 Aug 2019 12:00:00 -0400

Listen to our expert panelists talk about stem cells as a research tool and potential therapy for Parkinson’s.

Mentioned in this episode:

Podcast: Stem Cells and Parkinson’s Disease

Wed, 14 Aug 2019 12:00:00 -0400

Hear from our on-staff movement disorder specialist about the latest in Parkinson’s care and research.

Mentioned in this episode:

Podcast: Young-onset Parkinson’s Disease

Wed, 31 Jul 2019 12:00:00 -0400

Hear from our on-staff movement disorder specialist about the latest in Parkinson’s care and research.

Mentioned in this episode:

Podcast: Immune System’s Role in Parkinson’ s

Wed, 26 Jun 2019 12:00:00 -0400

Panelists discuss how inflammation may play a role in Parkinson’s and treatments using immune system properties against disease.

Mentioned in this episode:

Podcast: Looking Deep into Cells for the Answers to Parkinson's

Wed, 22 May 2019 12:00:00 -0400

Scientists discuss how reading the sequence of genes and proteins can help better define, measure and treat Parkinson's disease.

Mentioned in this episode:

Podcast: Repurposing Disappointments Impact on Parkinson's Drug Development

Wed, 08 May 2019 12:00:00 -0400

MJFF and NINDS leaders discuss results from trials of a dietary supplement and a blood pressure drug for Parkinson's and what is next in the pipeline.

Mentioned in this episode:

Podcast: Vision Problems in Parkinson's Disease

Wed, 24 Apr 2019 12:00:00 -0400

A brief summary of this episode

Mentioned in this episode:

Podcast: Latest in Parkinson's Research

Wed, 17 Apr 2019 12:00:00 -0400

The Michael J. Fox Foundation's Dr. Marco Baptista, Sohini Chowdhury and Dr. Rachel Dolhun talk to Dave Iverson about recent findings and new programs.

Mentioned in this episode:

Podcast: Q&A on Latest in Parkinson's Research

Wed, 17 Apr 2019 12:00:00 -0400

Staff from The Michael J. Fox Foundation answer questions from the audience at a recent panel discussion on progress in Parkinson's research.

Mentioned in this episode:

Podcast: Better Conversations and Care

Wed, 27 Mar 2019 12:00:00 -0400

In this Third Thursdays Webinar, physicians and people with Parkinson's discuss strategies to make doctor visits more effective and efficient.

Mentioned in this episode:

Podcast: Deep Brain Stimulation and Focused Ultrasound

Wed, 27 Feb 2019 12:00:00 -0400

Listen to our expert panelists talk about medical devices that can manage certain Parkinson's symptoms.

Mentioned in this episode:

Podcast: Levodopa Myths

Tue, 12 Feb 2019 12:00:00 -0400

Listen to Dr. Rachel Dolhun tackle widespread myths about levodopa.

Mentioned in this episode:

Addressing Gait and Balance Issues in Parkinson’s

Thu, 24 Jan 2019 12:00:00 -0400

Our panelists in this Third Thursdays Webinar discuss common Parkinson's motor symptoms and emerging treatments to target them.

Mentioned in this episode:

Podcast: Sleeping Well with Parkinson's

Wed, 26 Dec 2018 12:00:00 -0400

https://www.michaeljfox.org/foundation/news-detail.php?new-parkinson-drug-comes-to-market-after-early-investment-from-the-michael-fox-foundation

Mentioned in this episode:

Podcast: Parkinson's Will Double by 2040: Are We Ready?

Wed, 12 Dec 2018 12:00:00 -0400

Hear our panelists and co-authors of the paper "The Parkinson's Pandemic" discuss reasons for this global rise and strategies to contend with the issue.

Mentioned in this episode:

Podcast: Research Year in Review and Look Ahead

Wed, 21 Nov 2018 12:00:00 -0400

Listen to our expert panelists discuss the progress made in PD research over the last year and what to look forward to in 2019.

Mentioned in this episode:

Podcast: Visiting with Family Members Who Have Parkinson's

Fri, 16 Nov 2018 12:00:00 -0400

Listen to Dr. Rachel Dolhun's tips for making the most of holiday visits with family who have Parkinson's.

Mentioned in this episode:

Podcast: Treating Parkinson's 'Off' Episodes

Wed, 24 Oct 2018 12:00:00 -0400

In our latest podcast, listen to our Third Thursday Webinar panelists discuss 'off' times in Parkinson's.

Mentioned in this episode:

Podcast: How Genetic Discoveries Lead to Parkinson's Therapies

Wed, 10 Oct 2018 12:00:00 -0400

Listen to experts discuss the relationship between genetics and Parkinson's disease.

Mentioned in this episode:

Podcast: Dystonia Causes and Care

Wed, 26 Sep 2018 12:00:00 -0400

Listen to experts discuss the causes of dystonia and various treatment options.

Mentioned in this episode:

Podcast: Our MD Talks Muscle Cramps with Parkinson's

Wed, 12 Sep 2018 12:00:00 -0400

Hear from our on-staff movement disorder specialist about dystonia: a symptom of Parkinson's and standalone disorder that causes painful muscle cramps.

Mentioned in this episode:

Podcast: Urinary Problems in Parkinson's Disease

Wed, 22 Aug 2018 12:00:00 -0400

Listen to experts discuss treatments for urinary problems in Parkinson's disease.

Mentioned in this episode:

Podcast: Putting the Parkinson's Puzzle Together

Wed, 08 Aug 2018 12:00:00 -0400

One of our MJFF scientists talks about piecing together the many factors that play a role in Parkinson's and what can help us continue making progress.

Mentioned in this episode:

Podcast: What Is a Protein Anyway?

Fri, 04 May 2018 12:00:00 -0400

MJFF scientist Dr. Brian Fiske talks about what goes wrong with cellular proteins, how we may fix them and if you should eat less protein.

Mentioned in this episode:

Podcast: Addressing a Parkinson's Pandemic

Tue, 13 Mar 2018 12:00:00 -0400

Dr. Ray Dorsey from the University of Rochester discusses the rise in Parkinson's and how we can take steps to prevent onset and get people the care they need.

Mentioned in this episode:

Podcast: 2017 Parkinson's Research Year in Review

Fri, 22 Dec 2017 12:00:00 -0400

Missed our Year in Review webinar? Catch up with this recording and hear our panelists recap new potential Parkinson's treatments in clinical testing.

Mentioned in this episode:

Podcast: Cells' Recycling System

Fri, 15 Dec 2017 12:00:00 -0400

Autophagy is how cells break down and recycle damaged parts. We explain the link to Parkinson's and how treating autophagy may slow or stop disease.

Mentioned in this episode:

Podcast: Your Day Is Our Data

Mon, 13 Nov 2017 12:00:00 -0400

The online study Fox Insight analyzes data on life with disease from tens of thousands of people, with or without PD, to influence research focus and design.

Mentioned in this episode:

Podcast: Sniff Test for Parkinson's Disease

Tue, 17 Oct 2017 12:00:00 -0400

Measuring a person's scent or eye movements could lead to earlier PD diagnosis.

Mentioned in this episode:

Podcast: Measuring Feeling and Functional Impact of Dyskinesia

Wed, 20 Sep 2017 12:00:00 -0400

How does dyskinesia impact people with PD? An MJFF-funded measurement scale captured those perceptions and helped a new drug get approved to treat it.

Mentioned in this episode:

Podcast: Teaching Old Drugs New Tricks

Mon, 17 Jul 2017 12:00:00 -0400

Scientists are testing drugs used for high blood pressure and diabetes for their effects on Parkinson's disease. MJFF CEO Todd Sherer, PhD, discusses this tactic of drug repurposing.

Mentioned in this episode:

Podcast: Is Parkinson's an Autoimmune Disease?

Tue, 11 Jul 2017 12:00:00 -0400

In the latest in our "Getting to a Cure: Science behind the Search" series, we cover the proposed connection between sticky protein alpha-synuclein and the immune system.

Mentioned in this episode:

Podcast: Young-Onset Parkinson's Disease

Wed, 14 Jun 2017 12:00:00 -0400

Nancy Mulhearn, who was diagnosed with Parkinson’s at age 44, shares her experiences with the disease.

Mentioned in this episode:

Podcast: Sleep Disturbances in Parkinson's

Mon, 15 May 2017 12:00:00 -0400

Carlos Singer, MD, of the University of Miami discusses common sleep problems in Parkinson's and how to treat them.

Mentioned in this episode:

Podcast: Urinary Problems in Parkinson's Disease

Mon, 10 Apr 2017 12:00:00 -0400

Urinary function is governed by the body's autonomic nervous system. In Parkinson's, urinary function can be thrown off balance, but urinary problems aren't always recognized by patients.
Learn more at https://www.michaeljfox.org/clinical

Mentioned in this episode:

Podcast: Parkinson's Genetics

Mon, 06 Feb 2017 12:00:00 -0400

Barbara and Jay Robinson discuss their decision to participate in Parkinson's genetics research.

Mentioned in this episode:

Podcast: Gut Bacteria and Parkinson's Connection

Tue, 17 Jan 2017 12:00:00 -0400

Sarkis Mazmanian, PhD, of CalTech discusses what we know about the gut bacteria and Parkinson's connection in our "Getting to a Cure: The Science behind the Search" podcast series.

Mentioned in this episode:

Podcast: Parkinson's Common Denominator -- A Sticky Protein

Fri, 11 Nov 2016 12:00:00 -0400

Dr. Jamie Eberling, PhD, dicusses alpha-synuclein, a protein that clumps in brain cells of nearly everyone with Parkinson's disease.

Mentioned in this episode:

Podcast: Choosing Parkinson's Medications

Thu, 13 Oct 2016 12:00:00 -0400

In this podcast, Thomas Davis, MD, of Vanderbilt University Medical Center, speaks about how doctors and patients work together to create a medication regimen.

Mentioned in this episode:

Blood Pressure and Parkinson's

Thu, 13 Oct 2016 12:00:00 -0400

Dr. Anna Hohler speak to MJFF about blood pressure changes and Parkinson's disease.

Mentioned in this episode:

Podcast: Learning the Language of LRRK2

Tue, 11 Oct 2016 12:00:00 -0400

In this podcast, MJFF staff scientist Marco Baptista, PhD, discusses the genetics and biology of LRRK2 and the role of the Foundation in advancing development of LRRK2 therapeutics.

Mentioned in this episode:

Podcast: Atypical Parkinsonisms

Mon, 15 Aug 2016 12:00:00 -0400

Alex Pantelyat, MD, assistant professor of neurology at Johns Hopkins University, speaks to MJFF about atypical parkinsonisms and their relation to Parkinson’s disease.

Mentioned in this episode:

Podcast: Pain in Parkinson's

Mon, 18 Jul 2016 12:00:00 -0400

In this podcast, Dr. Julie Pilitsis speaks about Parkinson's pain and its connection to fatigue.

Mentioned in this episode:

Podcast: Treating Parkinson's Hallucinations and Delusions

Fri, 13 May 2016 12:00:00 -0400

Dr. Rachel Dolhun explores Parkinson's disease psychosis, including hallucinations and delusions, and discusses treatments for this symptom.

Mentioned in this episode:

Podcast: Parkinson's Personalized Medicine

Thu, 14 Apr 2016 12:00:00 -0400

MJFF's Dr. Brian Fiske discusses how we may be able to target treatments to the "type" of Parkinson's one has, much like is done in cancer care.

Mentioned in this episode:

Podcast: Efforts Toward Earlier Diagnosis

Mon, 14 Mar 2016 12:00:00 -0400

MJFF's Samantha Hutten, PhD, talks about how researchers are developing methods to identify people with PD earlier in the disease process, which could help test therapies to slow or stop Parkinson's.

Mentioned in this episode:

Podcast: Stem Cell-Derived Therapy 2.0

Wed, 17 Feb 2016 12:00:00 -0400

In our latest podcast, Dr. Ole Isacson, MD, PhD, a professor of neurology and neuroscience at Harvard Medical School, discusses stem cells and Parkinson's disease.

Mentioned in this episode:

Podcast: What Causes Dyskinesia?

Mon, 18 Jan 2016 12:00:00 -0400

In our latest podcast, Christopher Bishop, PhD, discusses what may cause involuntary movements called dyskinesia with long-term Parkinson's disease and medication use.

Mentioned in this episode:

Podcast: A Tool to Manage Tremor and Isolation

Wed, 06 Jan 2016 12:00:00 -0400

In our latest podcast the creator of Liftware talks about how he developed his tremor-stabilizing technology and how it helps people with Parkinson's fight isolation.

Mentioned in this episode:

Podcast: Parkinson's Research Roundup - 2015 Year in Review

Mon, 14 Dec 2015 12:00:00 -0400

Mark Frasier, PhD, Senior Vice President of Research Programs at MJFF, discusses Parkinson's disease research highlights from 2015.

Mentioned in this episode:

Podcast: Keeping Step with Parkinson’s: Balance, Posture and Gait

Fri, 13 Nov 2015 12:00:00 -0400

Dr. Chris Hass of the University of Florida explores balance, posture and gait issues and how to best protect from falls.

Mentioned in this episode:

Podcast: The Arts Impact on Parkinson's Disease

Wed, 28 Oct 2015 12:00:00 -0400

In our latest podcast, MJFF Contributing Editor Dave Iverson speaks with guest panelists about what dance offers people living with Parkinson's.

Mentioned in this episode:

Podcast: Therapies that May Slow or Stop Parkinson’s

Mon, 12 Oct 2015 12:00:00 -0400

MJFF CEO Todd Sherer, PhD, discusses therapies in human testing that have potential to slow or stop Parkinson's disease.

Mentioned in this episode:

Podcast: The Dystopian Experience of Dystonia

Wed, 30 Sep 2015 12:00:00 -0400

In our latest podcast Allison London shares how her dystonia has impacted her life and why she's on a mission to raise awareness.

Mentioned in this episode:

Podcast: Journalist Explores the Paths of Parkinson’s Research after His Own Diagnosis

Tue, 15 Sep 2015 12:00:00 -0400

Jon Palfreman has a new book exploring the history of Parkinson's research. He was diagnosed with PD in 2011 after spending years investigating rare cases of the disease for a documentary and book.

Mentioned in this episode:

Podcast: Parkinson’s Cognitive Issues and Treatment

Thu, 13 Aug 2015 12:00:00 -0400

MJFF's Dr. Jamie Eberling talks to Dave Iverson about what cognitive symptoms people with PD may experience and what new therapies are in development.

Mentioned in this episode:

Podcast: Complementary and Alternative Approaches for Parkinson’s

Mon, 11 May 2015 12:00:00 -0400

Dr. Laurie Mischley discusses some of the challenges that research into complementary and alternative approaches to managing Parkinson's face.

Mentioned in this episode:

Podcast: "Find Your Own Summit"

Fri, 03 Apr 2015 12:00:00 -0400

MJFF Contributing Editor Dave Iverson recently sat down with Sam to talk about how he turned his athletic talents into a career that honors his mother and the millions of others affected by PD.

Mentioned in this episode:

Podcast: Improving Deep Brain Stimulation

Mon, 16 Mar 2015 12:00:00 -0400

Our latest podcast covers how researchers are investigating ways to expand the current capabilities of deep brain stimulation.

Mentioned in this episode:

Podcast: How Genetics Has Transformed Parkinson’s Study

Wed, 11 Feb 2015 12:00:00 -0400

Geneticist Dr. Tatiana Foroud explains how the study of Parkinson's genetics can help develop new therapies.

Mentioned in this episode:

Podcast: How Can Exercise Help Manage Parkinson’s?

Fri, 09 Jan 2015 12:00:00 -0400

Dr. Lisa Shulman from the University of Maryland discusses how exercise may help manage Parkinson's motor and non-motor symptoms in our latest podcast.

Mentioned in this episode:

Podcast: Parkinson’s Research Year in Review

Mon, 15 Dec 2014 12:00:00 -0400

In our latest podcast. MJFF CEO Dr. Todd Sherer discusses the progress in Parkinson's research seen this year.

Mentioned in this episode:

Podcast: Strategies for Stopping Parkinson’s

Wed, 12 Nov 2014 12:00:00 -0400

We say Parkinson’s disease is different for each person, but there are a couple things all people with PD share: Lewy bodies and dopamine loss.

Mentioned in this episode:

Podcast: What Is Dystonia?

Tue, 14 Oct 2014 12:00:00 -0400

Dystonia is the third most common movement disorder and a symptom of Parkinson's disease. Bonnie Strauss talks about her experience, and Dr. Rachel Dolhun shares what we know about dystonia.

Mentioned in this episode:

Podcast: Meet the Newest Member of Your Care Team: The Smartwatch

Mon, 18 Aug 2014 12:00:00 -0400

Dr. William Marks talks to Dave Iverson about how wearable devices may help people with Parkinson's monitor their disease and help researchers test new therapies.

Mentioned in this episode:

Podcast: Six New Genetic Risk Factors for Parkinson's Identified

Wed, 30 Jul 2014 12:00:00 -0400

Scientists have found six new gene variants associated with Parkinson's, which could point to new treatment paths.

Mentioned in this episode:

Podcast: What Causes "Off" Episodes?

Mon, 16 Jun 2014 12:00:00 -0400

CEO Todd Sherer, PhD, talks to Dave Iverson about why levodopa loses efficacy over time and new therapies in development to even out on/off cycles.

Mentioned in this episode:

Podcast: Alzheimer’s and Parkinson’s, What’s the Connection?

Tue, 06 May 2014 12:00:00 -0400

Mark Frasier, PhD, VP of research programs at MJFF, discusses what we know about the overlap between Alzheimer's and Parkinson's diseases.

Mentioned in this episode:

Podcast: How Parkinson’s Variability Could Point to Personalized Treatments

Mon, 07 Apr 2014 12:00:00 -0400

The experience of Parkinson's disease is different for each patient. Studying that variability may allow researchers to develop personalized treatments for different subtypes of PD.

Mentioned in this episode:

Podcast: Drug That May Slow Parkinson’s Progression Granted $23 Million from NIH for Phase III Testing

Mon, 31 Mar 2014 12:00:00 -0400

Tanya Simuni, MD, principal investigator of the STEADY-PD, and MJFF CEO Todd Sherer talk about the study of isradipine, recently granted $23 million from the NIH for Phase III testing.

Mentioned in this episode:

Podcast: What Do Other Movement Disorders and Parkinson's Have in Common?

Wed, 12 Mar 2014 12:00:00 -0400

Biological commonalities between Parkinson's disease and other movement disorders could help researchers develop therapies that could apply across diagnostic barriers.

Mentioned in this episode:

Podcast: Parkinson’s Disease: What Else Goes Wrong?

Wed, 05 Feb 2014 12:00:00 -0400

Charles Adler, MD, PhD, talks to Dave Iverson about autonomic dysfunction symptoms and their place in research in our latest podcast.

Mentioned in this episode:

Podcast: The Long Road to Diagnosis

Tue, 31 Dec 2013 12:00:00 -0400

Dr. Kathleen Shannon of Rush University talks to Dave Iverson about the need for a definitive Parkinson's diagnostic test, what researchers are doing to develop one and how patients can help.

Mentioned in this episode:

Podcast: Inosine May Hold Potential for Parkinson’s Disease, but Patients Urged to Act with Caution

Mon, 23 Dec 2013 12:00:00 -0400

The SURE-PD study published in JAMA Neurology reports that with medical supervision, it is possible to safely raise levels of the antioxidant urate by taking the urate precursor inosine.

Mentioned in this episode:

Podcast: Research Year in Review

Tue, 26 Nov 2013 12:00:00 -0400

The Michael J. Fox Foundation Contributing Editor Dave Iverson speaks with Kalpana Merchant, PhD of Eli Lilly and Company about the latest in Parkinson's disease research.

Mentioned in this episode:

Podcast: Refining Deep Brain Stimulation

Mon, 18 Nov 2013 12:00:00 -0400

Researchers are improving on the existing DBS technology—an implanted electrode delivers electrical pulses to stimulate or block brain signals—and how we use it.

Mentioned in this episode:

Podcast: Pursuing a Tool to Visualize Alpha-Synuclein in the Brain

Fri, 08 Nov 2013 12:00:00 -0400

Levels of alpha-synuclein in the brain—measured through imaging tools—could be a biomarker that would help researchers diagnose the disease better and test potential therapies faster.

Mentioned in this episode:

Podcast: Whatever Happened to Stem Cells?

Tue, 29 Oct 2013 12:00:00 -0400

Contributing Editor Dave Iverson reports on the new technology that partnership will employ and the current state of stem cell research in Parkinson’s disease. He speaks

Mentioned in this episode:

Podcast: Prescribing Exercise to Treat Parkinson’s

Mon, 21 Oct 2013 12:00:00 -0400

While much research into Parkinson’s disease (PD) focuses on improving dopamine supply, there is an emerging scientific understanding that Parkinson’s goes well beyond the dopamine system.

Mentioned in this episode:

Podcast: Quicker Progress in Genetics

Mon, 09 Sep 2013 12:00:00 -0400

The evolution of our understanding of genetics’ role in Parkinson’s disease (PD) and how that understanding will translate into drug discovery is the topic of a new podcast and upcoming Webinar.

Mentioned in this episode:

Podcast: As Fox Trial Finder Reaches 20,000 Volunteers, One Volunteer Shares Her Story

Mon, 29 Jul 2013 12:00:00 -0400

Fox Trial Finder volunteer Gwen Schroeder recounts her first clinical trial experience to MJFF contributing editor Dave Iverson.

Mentioned in this episode:

Podcast: Improved Levodopa Delivery with Inhaled Formulation

Tue, 18 Jun 2013 12:00:00 -0400

Dave Iverson speaks with the CEO of Civitas, Glenn Batchelder, and MJFF staffer Maurizio Facheris, MD, MSc to learn more about how the drug works, as well as next steps.

Mentioned in this episode:

Podcast: PPMI Preliminary Research Begins to Provide Clues in Biomarker Search

Thu, 06 Jun 2013 12:00:00 -0400

Dave Iverson speaks with Foundation staffer Mark Frasier to learn more about some of the early findings from the study.

Mentioned in this episode:

Podcast: Discussing the Ceregene Clinical Trial Results

Fri, 26 Apr 2013 12:00:00 -0400

Dave Iverson reports on recent disappointing clinical trial results of Ceregene’s trophic factor therapy CERE-120.

Mentioned in this episode:

Podcast: Could a Nicotine Patch Slow the Progression of Parkinson’s Disease?

Wed, 06 Mar 2013 12:00:00 -0400

Studies have long suggested that smokers may be less likely to get Parkinson's. Here, Dave Iverson speaks with a researcher investigating the potential of nicotine patches as a PD treatment.

Mentioned in this episode:

Podcast: The State of Parkinson’s Disease Research

Tue, 12 Feb 2013 12:00:00 -0400

2013 could be a pivotal year in PD research, with expected developments on a variety of fronts. In this podcast, Dave Iverson speaks with Foundation staffers about some of that lies ahead.

Mentioned in this episode:

Podcast: The Decision to Get Genetically Tested

Wed, 22 Aug 2012 12:00:00 -0400

Emerging evidence over the past 15 years has led researchers to believe that genetics plays a far greater role in Parkinson’s disease (PD) than was once thought.

Mentioned in this episode:

Podcast: Engaged Parkinson's Patients Are the Answer to a Cure

Wed, 28 Mar 2012 12:00:00 -0400

Patients have always been at the heart of what we do at The Michael J. Fox Foundation. Our dedication to improving patients’ quality of life has shaped our research priorities.

Mentioned in this episode:

Podcast: Limiting On-Off Periods in Parkinson's Medications

Fri, 09 Mar 2012 12:00:00 -0400

While levodopa is the gold standard therapy for Parkinson's disease (PD), current delivery methods have their limitations.

Mentioned in this episode:

Podcast: What is the Connection Between Genetics and Environment in Parkinson's?

Thu, 08 Mar 2012 12:00:00 -0400

Understanding the genetics of Parkinson’s disease could be a game changer in developing new treatments for the disease. Especially when it comes to two genetic targets: LRRK2 and alpha-synuclein.

Mentioned in this episode:

Podcast: Teva Seeks Label Change for Azilect

Mon, 02 Jan 2012 12:00:00 -0400

This fall, The FDA recommended that Teva Neuroscience’s drug rasagiline, brand name Azilect, should not be granted status “to slow the clinical progression of PD.”

Mentioned in this episode:

Podcast: A Vaccine Approach to Treating Parkinson's Disease

Sun, 18 Dec 2011 12:00:00 -0400

This past October, Austrian biotech AFFiRiS announced $1.5 million in funding from MJFF for an early stage clinical trial of a first-of-its-kind vaccine approach to treating Parkinson's disease (PD).

Mentioned in this episode: